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Search suggestions for "5392-40-5".

  1. CEBS Data Related to Citral (5392-40-5) https://cebs.niehs.nih.gov/cebs/test_article/5392-40-5


62 results found for "5392-40-5".

  1. TR-505: Citral (Microencapsulated) (CASRN 5392-40-5) in F344... 10.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr505.pdf

    THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF CITRAL (MICROENCAPSULATED) (CAS NO. 5392-40-5) IN F344/N RATS AND B6C3F 1 MICE (FEED STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box ...

  2. Abstract for TR-505 71KB

    https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr505

    Abstract for TR-505 Toxicology and Carcinogenesis Studies of Citral (Microencapsulated) in F344/N Rats and B6C3F1 Mice (Feed Studies) CASRN: 5392-40-5 Chemical Formula: C10H16O ...

  3. Target Organs and Levels of Evidence for TR-505 57KB

    https://ntp.niehs.nih.gov/data/tr/500s/tr505levels

    Target Organs and Levels of Evidence for TR-505 Toxicology and Carcinogenesis Studies of Citral (Microencapsulated) (CASRN 5392-40-5) in F344/N Rats and B6C3F1 Mice (Feed Studies) ...

  4. Minutes: BSC TRRS; May 3, 2001 62KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2001/may/trrs3may2001mins_508.pdf

    107-13-1 Gavage, mice 5 Methacrylonitrile 126-98-7 Gavage Rats, Mice 6 Citral 5392-40-5 Feed Rats, Mice 7 2 Summary Minutes NTP Board of Scientific Counselors Technical ...

  5. Historical Controls: All Routes and Vehicles for Mice; Studies... 255KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2006/m_hcrpt_allrte2006_508.pdf

    06/19/96 727 100(1) 91(707) 48.4 Citral Battelle Northwest 059601106 06/11/01 729 ... 055634804 06/20/96 733 99(5) 81(695) 47.7 Citral Battelle Northwest 059601106 06/11/01 731 ...

  6. Historical Controls: All Routes and Vehicles for Rats; Studies... 270KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2006/r_hcrpt_allrte2006_508.pdf

    06/06/96 726 100(3) 52(681) 491.2 Citral Battelle Northwest 059601105 06/04/01 729 ... 06/07/96 732 100(5) 75(705) 335.0 Citral Battelle Northwest 059601105 06/04/01 731 ...

  7. Vagina - Dilation - Nonneoplastic Lesion Atlas 287KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/vagina/Dilation

    National Toxicology Program. 2003. NTP TR-505. Toxicology and Carcinogenesis Studies of Citral (Microencapsulated) (CAS No. 5392-40-5) in F344/N Rats and B6C3F1 Mice (Feed ...

  8. Vagina - Dilation 230KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/female_reproductive/vagina/dilat/vagina-dilation-pdf-508.pdf

    Program. 2003. NTP TR-505. Toxicology and Carcinogenesis Studies of Citral (Microencapsulated) (CAS No. 5392-40-5) in F344/N Rats and B6C3F 1 Mice (Feed Studies). NTP, Research ...

  9. Spleen - Adipocyte Metaplasia - Nonneoplastic Lesion Atlas 288KB

    https://ntp.niehs.nih.gov/atlas/nnl/immune-system/spleen/AdipocyteMetaplasia

    National Toxicology Program. 2003. NTP TR-505. Toxicology and Carcinogenesis Studies of Citral (Microencapsulated) (CAS No. 5392-40-5) in F344/N Rats and B6C3F1 Mice (Feed ...

  10. Spleen - Adipocyte Metaplasia 314KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/immune/spleen/admetap/spleen-adipocyte-metaplasia-pdf_508.pdf

    Toxicology Program. 2003. NTP TR-505. Toxicology and Carcinogenesis Studies of Citral (Microencapsulated) (CAS No. 5392-40-5) in F344/N Rats and B6C3F1 Mice (Feed Studies). ...

  11. Cover Letter for Nomination of IVSA to ICCVAM (2012) 531KB

    https://ntp.niehs.nih.gov/iccvam/methods/immunotox/ivsa/ivsa-iccvamsubmissionletter-092712-508.pdf

    .../19/12 EtOH, H 2 O C 9 H 10 O 134.18 solid Weak EtOH 5% 0.40 - 14.0% 04/19/12 4 Citral CIT 5392-40-5 Aldrich EtOH 1% 0.60 - 2.1% 04/19/12 EtOH, H 2 O C 10 H 16 O 152.23 liquid Weak ...

  12. ICCVAM Test Method Evaluation Report on the LLNA: DA 30.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-da/tmer.pdf

    ... Compounds; Lipids 8.080 (8.9) 1.640 (3.4) Citral 5 Fragrance agent Hydrocarbons, Other ... 13.00, 13.10, 16.10, 16.10, 19.10, 33.60 Citral (1, 4) AOO 4.40 4.70, 6.20, 9.30, 20.50 ...

  13. Recommended Performance Standards for the LLNA 2.2MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf

    ... AS, Schwoeppe EA, et al. 1980. Citral: a survey of consumer patch-test sensitization. ... Sol DMF 1.7 1 0.85-3.4 NC +/+ +/+ 7 Citral 5392-40-5 Liq AOO 9.2 6 4.6-18.3 5.1-13 ...

  14. ICCVAM Test Method Evaluation Report: LLNA BrdU-ELISA 35.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-elisa/tmer.pdf

    ... Compounds; Lipids 8.1 (8.9) 13.334 (2.6) Citral * Fragrance agent Hydrocarbons, Other 9.2 ... DMF 1.62 4.60, 9.10, 9.50, 10.80, 17.10 Citral (1,4) AOO 16.40 4.70, 6.20, 9.30, 20.50 ...

  15. Advancing Flexibility for Defined Approach Guidelines: Developing... 1.2MB

    https://ntp.niehs.nih.gov/sites/default/files/2024-03/SOT2024-Sullivan-poster.pdf

    ... 1A 1 1A Bromothalonil 35691-65-7 Y N/A 1A 1 1A Butan-1-ol 71-36-3 Y N/A NC NC NC Citral 5392-40-5 N N/A 1B 1 1A EGDMA 97-90-5 Y N/A 1B 1 1B Ethylene diamine (free base) 107-15-3 N ...

  16. Presentation: The Murine Local Lymph Node Assay: BrdU-ELISA 889KB

    https://ntp.niehs.nih.gov/iccvam/meetings/implement-2011/acd-present/6-strickland.pdf

    ... isothiazolin-3-one Cinnamic alcohol Cinnamic aldehyde trans-Cinnamic aldehyde Citral Cobalt chloride Cyclamen aldehyde Diethyl maleate 2,4- Dinitrochlorobenzene ...

  17. Presentation: The Murine Local Lymph Node Assay: DA 1010KB

    https://ntp.niehs.nih.gov/iccvam/meetings/implement-2011/acd-present/7-salicru.pdf

    ... Abietic acid 3-Aminophenol Benzalkonium chloride p-Benzoquinone Butyl glycidyl ether 5-Chloro-2-methyl-4- isothiazolin-3-one Cinnamic alcohol Cinnamic aldehyde Citral Cobalt ...

  18. Reproducing the ITS-2 Model Using R 472KB

    https://ntp.niehs.nih.gov/iccvam/methods/immunotox/its-os/its2_r_version-508.pdf

    ... 0.828779 0.001618 0.001438 0.168164 5392-40-5 0.005458 0.065849 0.906857 0.021835 ... 0.828779 0.001618 0.001438 0.168164 5392-40-5 0.005458 0.065849 0.906857 0.021835 ...

  19. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... Not Tested in Species/Sex P Clear Evidence P Clear Evidence TR-505 05/03/01 Citral 5392-40-5 NE No Evidence NE No Evidence NE No Evidence EE Equivocal Evidence TR-504 05/03/...

  20. TR-570: Alpha,Beta-Thujone (CASRN 76231-76-0) in F344/N Rats... 15.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr570.pdf

    ... pinocamphone from hyssop, fenchone from fennel, and citral from lemon balm (Arnold, 1989). ... 2010). Furthermore, camphor, 1,8-cineole, citral, and citronellal (all monoterpenes) were ...

  21. Usefulness and Limitations of the LLNA for Potency Categorization... 25.3MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-pot/tmer.pdf

    ... 1.67 2 0.56 2 1.09 1.36 1.06 2 0.42 2 + + Citral 8.48 2 4.94 2 2.75 2 + + Coumarin NC ... 732 b 550 Dihydrocoumarin b 769 1402 Citral a,f 775 3300 Benzoyl peroxide b 895 41 ...

  22. Minutes: BSC; Sept. 27, 1983 638KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1983/september/bsc_mins19830927_508.pdf

    ... Six were nitropyrenes and the seventh was 2,4,7-trinitrofluoren-9-one (TNF) . The other five com- pounds were aliphatic aldehydes, namely formaldehyde, citral, butyralde hyde, ...

  23. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... TR-505 PDF (10.89 MB) Toxicology and Carcinogenesis Studies of Citral (Microencapsulated) (CASRN 5392-40-5) in F344/N Rats and B6C3F1 Mice (Feed Studies) 2003 Technical ...

  24. TR-514: trans-Cinnamaldehyde (Microencapsulated) (CASRN 14371... 8.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr514.pdf

    ... Furthermore, in the citral (CAS No. 5392-40-5) study where microcapsules were used as a vehicle, none of these lesions differed significantly between the untreated and vehicle ...

  25. TR-504: o-Nitrotoluene (CASRN 88-72-2) in F344/N Rats and B6C3F1... 14.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr504.pdf

    ... in Controls Given NTP-2000 Diet a Citral (feed) 4/100 p,pN-Dichlorodiphenyl ... in Controls Given NTP-2000 Diet a Citral (feed) 0/100 2/100 2/100 4/100 ...

  26. Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf

    ... Irritant (60/1048) & sensitizer (62/1048) in dermatitis patients. Citral// 3,7-Dimethyl-2,6- octadienal// Geranial-Neral mixture 5392-40-5 terpene alcohol// potential Michael- ...

  27. OECD Test Guideline 429: Skin Sensitisation: Local Lymph Node... 291KB

    https://ntp.niehs.nih.gov/iccvam/suppdocs/feddocs/oecd/oecd-tg429-2010.pdf

    ... +/+ +/+ 6 2-Mercaptobenzothiazole 149-30-4 Sol DMF 1.7 1 0.85-3.4 NC +/+ +/+ 7 Citral 5392-40-5 Liq AOO 9.2 6 4.6-18.3 5.1-13 +/+ +/+ 8 HCA 101-86-0 Liq AOO 9.7 21 4.8-19.5 ...

  28. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... TR-505 PDF (10.89 MB) Toxicology and Carcinogenesis Studies of Citral (Microencapsulated) (CASRN 5392-40-5) in F344/N Rats and B6C3F1 Mice (Feed Studies) 2003 Long-Term ...

  29. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... TR-505 PDF (10.89 MB) Toxicology and Carcinogenesis Studies of Citral (Microencapsulated) (CASRN 5392-40-5) in F344/N Rats and B6C3F1 Mice (Feed Studies) 2003 Technical ...

  30. TR-508: Riddelliine (CASRN 23246-96-0) in F344/N Rats and B6C3F1Mice... 9.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr508.pdf

    ... in Controls Given NTP-2000 Diet a Citral (feed) 0/100 0/100 p,pN-Dichlorodiphenyl ... in Controls Given NTP-2000 Diet a Citral (feed) 68/100 p,pN-Dichlorodiphenyl ...

  31. TR-498: p-Nitrotoluene (CASRN 99-99-0) in F344/N Rats and B6C3F1Mice... 10.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr498.pdf

    ... in Controls Given NTP-2000 Diet a Citral (feed) 2/100 2/100 4/100 ... in Controls Given NTP-2000 Diet a Citral (feed) 68/100 p,pN-Dichlorodiphenyl ...

  32. National Toxicology Program, Board of Scientific Counselors 106KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2001/may/2001052501bscsummmins_508.pdf

    ... Citral (TR-505) - lemon flavoring and fragrance used widely in foods, cosmetics, and other consumer products - exposure by microcapsules mixed in animals' feed - equivocal evidence ...

  33. TR-516: 2-Methylimidazole (CASRN 693-98-1) in F344/N Rats and... 9.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr516.pdf

    ... trans-Cinnamaldehyde 1/50 1/50 2/50 Citral 3/50 1/50 4/50 p,pN-Dichlorodiphenyl ... trans-Cinnamaldehyde 1/50 0/50 1/50 Citral 0/50 0/50 0/50 p,pN-Dichlorodiphenyl ...

  34. TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB

    https://ntp.niehs.nih.gov/go/tr518

    ... (feed) 0/100 0/100 0/100 Citral (feed) 0/100 2/100 0/100 Decalin ... (feed) 3/100 2/100 5/100 Citral (feed) 2/100 3/100 5/100 Decalin ...

  35. TR-506: Acrylonitrile (CASRN 107-13-1) in B6C3F1Mice (Gavage... 7.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr506.pdf

    ... a Acrylonitrile (gavage) 3/50 0/50 3/50 Citral (feed) 0/100 0/100 0/100 ... a Acrylonitrile (gavage) 5/50 1/50 6/50 Citral (feed) 4/100 0/100 4/100 ...

  36. TR-509: 2,4-Hexadienal (89% trans,trans Isomer, CASRN 142-83... 10.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr509.pdf

    ... in Controls Given NTP-2000 Diet a Citral (feed) 0/100 0/100 0/100 ... in Controls Given NTP-2000 Diet a Citral (feed) 0/100 0/100 0/100 ...

  37. TR-513: Decalin (CASRN 91-17-8) in F344/N Rats and B6C3F1Mice... 11.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr513.pdf

    ... (feed) 0/100 0/100 0/100 Citral (feed) 0/100 0/100 0/100 Decalin ... (feed) 5/100 0/100 5/100 Citral (feed) 10/100 0/100 10/100 Decalin ...

  38. TR-533: Benzophenone (CASRN 119-61-9) in F344/N Rats and B6C3F1Mice... 10.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr533.pdf

    ... Given NTP-2000 Diet Benzophenone 1/50 Citral 0/100 p,pN-Dichlorodiphenyl sulfone 0/50 ... Given NTP-2000 Diet Benzophenone 27/50 Citral 68/100 p,pN-Dichlorodiphenyl sulfone 27/...

  39. ICCVAM Test Method Evaluation Report on the Reduced LLNA 21.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ld/tmer.pdf

    ... - 2277-19-2 140.23 2.29 Liquid Aldehydes Gerberick Citral 3,7-Dimethyl-2,6- octadienal; Geranial- Neral mixture 5392-40-5 152.23 2.54/ 3.45 Liquid Hydrocarbons, Other Lalko & ...

  40. TOX-81: α-Pinene (CASRN 80-56-8) Administered by Inhalation... 2.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox081_508.pdf

    ... by the NTP, including β-myrcene 77 , d-limonene 78 , citral 79 , geranyl acetate 80 and α,β-thujone 81 . α-Pinene, citral, and d-limonene elicited kidney lesions in male rats ...

  41. Minutes: BSC; May 24, 2000 495KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2000/may/2000052400bscsummmins_508.pdf

    ... This includes acrylonitrile (mouse), methacrylonitrile, o-nitrotoluene, p-nitrotoluene, citral, vanadium pentoxide, riddelliine (seven doses), and urethane/ethanol Discussion: Dr. ...

  42. Minutes: BSC; Feb. 5, 1998 713KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1998/february/19980205bscmins_508.pdf

    ... citral and b- myrcene because of similarity of structures Linalool [78-70-6] NCI mechanistic studies; metabolism; carcinogenicity; mutagenicity await results from testing citral ...

  43. TOX-55: trans-1,2-Dichloroethylene (CASRN 156-60-5) 3.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox055.pdf

    ... Comparison of the toxicity of citral in F344 rats and B6C3F 1 mice when administered by ... Toxicology and Carcinogenesis Studies of Citral (Microencapsulated) (CAS No. 5392-40-5) in ...

  44. TR-507: Vanadium Pentoxide (CASRN 1314-62-1) in F344/N Rats and... 6.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr507.pdf

    ... in Controls Given NTP-2000 Diet a Citral (feed) 3/100 0/100 3/100 ... in Controls Given NTP-2000 Diet a Citral (feed) 2/100 1/100 3/100 ...

  45. TOX-14: p-Chloro-a,a,a-Trifluorotoluene (CASRN 98-56-6) 2.2MB

    https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox014.pdf

    ... and volatile chemicals such as trichloroethane, 2-ethylhexanol, cinnamaldehyde, and citral were successfully encapsulated using a starch-and-geletin mixture as the shell material. ...

  46. TR-512: Elmiron (CASRN 37319-17-8) in F344/N Rats and B6C3F1Mice... 12.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr512.pdf

    ... (feed) 0/100 14/100 13/100 26/100 Citral (feed) 2/100 20/100 13/100 28/100 Decalin ... (feed) 4/100 1/100 5/100 Citral (feed) 1/99 0/99 1/99 Decalin ...

  47. TR-535: 4-Methylimidazole (CASRN 822-36-6) in F344/N Rats and... 10.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr535.pdf

    ... 19/50 trans-Cinnamaldehyde 21/100 Citral 24/100 p,p´-Dichlorodiphenyl sulfone 8/... trans-Cinnamaldehyde 9/100 7/100 14/100 Citral 12/100 9/100 20/100 p,p´-Dichlorodipheny...

  48. TR-523: Diisopropylcarbodiimide (CASRN 693-13-0) in F344/N Rats... 10.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr523.pdf

    ... (feed) 5/100 0/100 0/100 5/100 Citral (feed) 10/100 1/100 0/100 11/100 Decalin ... 1/50 trans-Cinnamaldehyde (feed) 2/100 Citral (feed) 6/99 Decalin (inhalation) 6/49 ...

  49. Peer Review Panel Report: Updated Validation Status of the LLNA... 807KB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llnaprprept2009.pdf

    ... 1 11.94 +/+ +/+ +/+ 12 Cinnamic alcohol 104-54-1 Sol AOO 1 12.20 +/+ +/+ +/+ 13 Citral 5392-40-5 Liq AOO 1 12.46 +/+ +/+ +/+ 14 Diethyl phthalate 84-66-2 Liq AOO 1 NA -/- -/- -/- ...

  50. Nomination Background: p-Synephrine (CASRN: 94-07-5) 1.3MB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/bitterorange_508.pdf

    ... Plant CAPRINALDEHYDE Plant CARVONE Plant CARYOPHYLLENE Plant CINNAMIC-ACID Plant CITRAL Plant CITRIC-ACID Plant 54 CITRONELLAL Plant CITRONELLOL Plant CRYPTOXANTHIN Plant ...

 
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