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Search suggestions for "54-31-9".

  1. CEBS Data Related to Furosemide (54-31-9) https://cebs.niehs.nih.gov/cebs/test_article/54-31-9


89 results found for "54-31-9".

  1. TR-356: Furosemide (CASRN 54-31-9) in F344/N Rats and B6C3F1Mice... 11.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr356.pdf

    6 TOXICOLOGY AND CARCINOGENESIS STUDIES OF FUROSEMIDE (CAS NO. 54-31-9) IN F344/N RATS AND B6C3F1 MICE (FEED STUDIES) U.S. DEPARTMENT O F HEALTH AND HUMAN SERVICES Public Health ...

  2. Abstract for TR-356 68KB

    https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr356

    Abstract for TR-356 Toxicology and Carcinogenesis Studies of Furosemide in F344/N Rats and B6C3F1 Mice (Feed Studies) CASRN: 54-31-9 Chemical Formula: C12H11ClN2O5S Molecular ...

  3. Target Organs and Levels of Evidence for TR-356 58KB

    https://ntp.niehs.nih.gov/data/tr/300s/tr356levels

    Target Organs and Levels of Evidence for TR-356 Toxicology and Carcinogenesis Studies of Furosemide (CASRN 54-31-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) Chemical (Study ...

  4. Minutes: BSC TRRS; April 18, 1988 4.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1988/apr/88apr18trrsmins_508.pdf

    Hart, (919) 541-3971; FTS1 629-3971. ~TENTS Tecmical Reports CAS No. p-Chloroan!Une !06-47-8 2,4-0ichlorophenol 120-83-2 Furosemide 54-31-9 Hydrochlorothiazide 58-93-5 d-Umonene ...

  5. Minutes: BSC TRRS; Oct. 3, 1988 964KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1988/oct/88oct3-4trrsmins_508.pdf

    Previously Approved Study - N e w Data Furosemide: Further Pathology Findings From ... Furosemide: Further Pathology Findings from Kidneys of Male Rats. The NTP toxicology and ...

  6. TR-402: Furan (CASRN 110-00-9) in F344 Rats and B6C3F1 Mice(Gavage... 31.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr402.pdf

    ... amine to incubation mixtures containing furosemide and mouse liver microsomes ... In the same experimental system, furosemide was more toxic to the liver than to the ...

  7. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... No Evidence NE No Evidence EE Equivocal Evidence NE No Evidence TR-356 04/18/88 Furosemide 54-31-9 EE Equivocal Evidence NE No Evidence NE No Evidence SE Some Evidence TR-355 10/...

  8. RoC Background Document: Furan; Nov. 18-19, 1996 3.0MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/furan1_508.pdf

    ... This has been demonstrated in vitro for furosemide (for reviews see Burka and Boyd, 1985; ... 3-methylfuran, 4-ipomeanol, furamide, furosemide, and ngaione require P-450-mediated ...

  9. TR-357: Hydrochlorothiazide (CASRN 58-93-5) in F344/N Rats and... 12.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr357.pdf

    ... Prostaglandin biosynthesis is thought to be involved in the in- crease in renal renin release in response to loop diuretics such as furosemide (Gerber, 19831, but 15 ...

  10. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... Report TR-356 PDF (11.65 MB) Toxicology and Carcinogenesis Studies of Furosemide (CASRN 54-31-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1989 Technical Report TR-355 ...

  11. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... TR-356 PDF (11.65 MB) Toxicology and Carcinogenesis Studies of Furosemide (CASRN 54-31-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1989 Long-Term Carcinogenicity ...

  12. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... Report TR-356 PDF (11.65 MB) Toxicology and Carcinogenesis Studies of Furosemide (CASRN 54-31-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1989 Technical Report TR-355 ...

  13. TR-411: C.I. Pigment Red 23 (CASRN 6471-49-4) in F344 Rats and... 15.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr411.pdf

    ... as nitrofurantoin (NTF', 1989a), furosemide (1989c), and hydroquinone ( N T P , 1989e). ... Toxicology and Carcinogenesis Studies o f Furosemide (CAS No. 54-31-9) in F344/N Rats and ...

  14. Background Document: RoC: Aristolochic Acids ; 2010 2.7MB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/aristolochic_acids_final_508.pdf

    ... All rats received a single intraperitoneal (i.p.) injection of furosemide at a dose of 4 ... on day 35 salt depletion induced by furosemide and low-salt, normal protein diet ...

  15. TR-420: Triamterene (CASRN 396-01-0) in F344/N Rats and B6C3F1Mice... 20.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr420.pdf

    ... Pharmacokinetic and pharmacodynamicstudy of the combination o f furosemide retard and ... 355 Diphenhydramine Hydrochloride 356 Furosemide 357 Hydrochlorothiazide 358 Ochratoxin ...

  16. TR-442: p-Nitrobenzoic Acid (CASRN 62-23-7) in F344/N Rats and... 15.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr442.pdf

    ... a-Methylbenzyl Alcohol Phenylbutazone Furosemide 0160 1/49 2/50 2/50 5/60 1/49 0150 2/50 ... Study Single and Step Sections Combined Nitrofurantoin Furosemide Phenylbutazone ...

  17. TR-236: D-Mannitol (CASRN 69-65-8) in F344/N Rats and B6C3F1Mice... 6.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr236.pdf

    ... Squire, R.; Levitt, M., Report of a workshop on classification of specific hepatocellular lesions in rats. Cancer Res. 35:3214; 1975. Sonnenberg, H., Effects of furosemide, ...

  18. TR-370: Benzofuran (CASRN 271-89-6) in F344/N Rats and B6C3F1Mice... 12.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr370.pdf

    ... Mutagen. 11:91-118. 27. McMurtry, R.J.; Mitchell, J.R. (1977) Renal and hepatic necrosis after metabolic activation of 2-substituted furans and thiophenes, includ- ing furosemide ...

  19. TR-382: Furfural (CASRN 98-01-1) in F344/N Rats and B6C3F1Mice... 11.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr382.pdf

    ... R.J.; Mitchell, J.R. (1977) Renal and hepatic necrosis after metabolic activation of 2-substituted furans and thiophenes, includ- ing furosemide and cephaloridine. Toxicol. Appl. ...

  20. RoC Background Document: Cyclosporin A; Nov. 18-19, 1996 4.9MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/cyclosporin_a1_508.pdf

    ... (3.6 mg/kg/day), minoxidil, propranolol, furosemide, nifedipine, and prednisone. ... (2.6 mg/kg/day), minoxidil, captopril, furosemide, prednisone, and theophylline. ...

  21. TR-367: Phenylbutazone (CASRN 50-33-9) in F344/N Rats and B6C3F1Mice... 10.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr367.pdf

    ... IN SELECTED CONTROL GROUPS OF MALE F344/N RATS IN NTP STUDIES Nitrofurantoin (a) Furosemide (b) Toluene (c) Phenilbutazone (d) Total Lesion Single (e) Number of animals 50 ...

  22. Report: International Workshop on In Vitro Methods for Assessing... 25.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf

    ... 18.2 NA NA 346.41 18.2 109 Frusemide 54-31-9 770.67 2.33 2599.8 7.86 4597.6 13.9 ... 3700.9 13.3 278.26 9.34 109 Frusemide 54-31-9 770.67 2.33 2599.8 7.86 4597.6 13.9 ...

  23. ICCVAM Background Review Document: Validation Status of Five... 10.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/pyrogen/brd/pyrobrd2008.pdf

    ... Ranitidine - 25 mg/mL 1 <6 1.2-2.4 Pass Pantoprazol - 40 mg/10 mL 1 <6 <0.06 Pass Furosemide - 10 mg/mL 2 <0.6 <0.06 Pass rec-hGH - 4 IU/vial A 2 <0.2 <0.06 Pass rec-hGH - 4 IU/...

  24. TR-371: Toluene (CASRN108-88-3) in F344/N Rats and B6C3F1Mice... 15.6MB

    https://ntp.niehs.nih.gov/go/tr371

    ... NTP, 1 9 8 9 ~ ) or an increase of two (furosemide, 1/50 to 3/50; NTP, 1989d) or three ... Toxicology and Carcinogenesis Studies of Furosemide in F344/N Rats and B6C3F1 Mice. ...

  25. TR-597: 2-Hydroxy-4-methoxybenzophenone (CASRN 131-57-7) Administered... 3.2MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr597_508.pdf

    ... and Carcinogenesis Studies of Furosemide) that found three meningiomas, all in ... NTP techical report on the toxicology and carcinogenesis studies of furosemide (CAS No. ...

  26. TR-573: Styrene-acrylonitrile trimer in F344/N Rats (Perinatal... 5.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr573_508.pdf

    ... 0/49 0/49 4/50 (8%) Glioma 1/49 (2%) 0/49 1/50 (2%) TR 356: 2-Year Feed Study of Furosemide 0 ppm 350 ppm 700 ppm Male (Equivocal Evidence) Astrocytoma 1/50 (2%) 1/50 (2%) 0/50 ...

  27. TR-417: p-Nitrophenol (CASRN 100-02-7) in Swiss Webster Mice... 7.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr417.pdf

    ... Dimethoxane 394 Acetaminophen 355 Diphenhydramine Hydrochloride 395 Probenecid 356 Furosemide 3% Monochloroacetic Acid 357 Hydrochlorothiazide 397 C.I. Direct Blue 15 358 ...

  28. TR-444: Initiation/Promotion Study of o-Benzyl-p-Chlorophenol... 6.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr444.pdf

    ... N-Methylolacrylamide 2,4-Dichlorophenol Dimethoxane Diphenhydramine Hydrochloride Furosemide Hydrochlorothiazide Ochratoxin A 8-Methoxypsoralen N,N-Dimethylaniline ...

  29. TR-410: Naphthalene (CASRN 91-20-3) in B6C3F1Mice (Inhalation... 8.6MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr410.pdf

    ... Epinephrine Hydrochloride 2-Chloroacetophenone Benzaldehyde 356 355 354 353 352 351 Furosemide Diphenhydramine Hydrochloride Dimethaxane 2,4-Dichlorophenol N-Methylohcryhmide ...

  30. TR-389: Sodium Azide (CASRN 26628-22-8) in F344 Rats (Gavage... 8.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr389.pdf

    ... 353 2,4-Dichlorophenol 354 Dimethoxane 355 Diphenhydramine Hydrochloride 356 Furosemide 357 Hydrochlorolhiazide 358 Ochratoxin A 359 8-Methoxypsoralen 360 ...

  31. TR-278: 2,6-Xylidine (2,6-Dimethylaniline) (CASRN 87-62-7) in... 9.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr278.pdf

    ... Roxarsonu a-Methyldopa Sesquihydrate Pentachlorophenol Tribromomethane 2,4-Dichlorophenol Furosemide Hydrochlorothiazide OchratoxinA 8-Methoxypsoralen Hexachloroethane These NTP ...

  32. TR-399: Titanocene Dichloride (CASRN 1271-19-8) in F344/N Rats... 8.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr399.pdf

    ... Dimethoxane Diphenhydramine Hydrochloride Furosemide Hydrochlorothiazide Ochratoxin A 8-Methoxypmralen N,N-Dimethylaniline Hexachloroethane 4-Vinyl-1-Cyclohexene Diepoxide TR No. ...

  33. TR-413: Ethylene Glycol (CASRN 107-21-1) in B6C3F1Mice (Feed... 11.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr413.pdf

    ... 393 Sodium Fluoride 355 Diphenhydramine Hydrochloride 394 Acetaminophen 356 Furosemide 395 Probenecid 357 Hydrochlorothiazide 396 Monochloroacetic Acid 358 Ochratoxin A ...

  34. TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB

    https://ntp.niehs.nih.gov/go/tr518

    ... Thiourea Eugenol FD&C Yellow No. 6 Fumonisin B 1 Furan Furfural Furfuryl Alcohol Furosemide Gallium Arsenide Geranyl Acetate Glutaraldehyde Glycidol Guar Gum Gum Arabic HC Blue ...

  35. TR-373: Succinic Anhydride (CASRN 108-30-5) in F344/N Rats and... 21.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr373.pdf

    ... a-Methyldopa Sesquihydrate Pentachlorophenol Tribromomethane 2,4-Dichlorophenol Furosemide Hydrochlorothiazide Ochratoxin A 8-Methoxypsoralen Hexachloroethane These NTP ...

  36. TR-387: dl-Amphetamine Sulfate (CASRN 60-13-9) in F344/N Rats... 10.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr387.pdf

    ... Ether o-Chlorobenzalmalononitnle Benzaldehyde 355 356 Diphenhydramine Hydrochloride Furosemide 379 380 2-Chloroacetophenone Epinephrine Hydrochloride 357 358 Hydrochlorothiazide ...

  37. TR-368: Nalidixic Acid (CASRN 389-08-2) in F344/N Rats and B6C3F1Mice... 13.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr368.pdf

    ... Roxarsone a-Methyldopa Sesquihydrate Pentachlorophenol Tribromomethane 2,4-Dichlorophenol Furosemide Hydrochlorothiazide Ochratoxin A 8-Methoxypsoralen Hexachloroethane These NTP ...

  38. TR-391: Tris(2-chloroethyl) Phosphate (CASRN 115-96-8) in F344... 11.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr391.pdf

    ... Benzaldehyde o-Chlorobenzalmalononitrile AllylGlycidyl Ether VinylToluene 356 355 Furosemide Diphenhydramine Hydrochloride 380 379 Epinephrine Hydrochloride 2-Chloroacetophenone ...

  39. TR-400: 2,3-Dibromo-1-Propanol (CASRN 96-13-9) in F344/N Rats... 11.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr400.pdf

    ... 2,4-Diaminophenol Dihydrochloride 355 Diphenhydramine Hydrochloride 402 Furan 356 Furosemide 403 Resorcinol 357 Hydrochlorothiazide 404 5,S-Diphenylhydantoin 358 Ochratoxin A ...

  40. TR-401: 2,4-Diaminophenol Dihydrochloride (CASRN 137-09-7) in... 12.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr401.pdf

    ... Epinephrine Hydrochloride 2-Chlomcetophenone Benzaldehyde 356 355 354 353 352 3 5 1 Furosemide Diphenhydramine Hydrochloride Dimethoxane 2.4-Dichiorophenol N-MethybLauylamide ...

  41. TR-502: Chloral Hydrate (CASRN 302-17-0) in B6C3F1Mice (Gavage... 8.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr502.pdf

    ... Ethylene Glycol Ethylene Glycol Monobutyl Ether Ethylene Oxide Ethylene Thiourea Eugenol FD&C Yellow No. 6 Fumonisin B 1 Furan Furfural Furfuryl Alcohol Furosemide Gallium Arsenide ...

  42. TR-385: Methyl Bromide (CASRN 74-83-9) in B6C3F1Mice (Inhalation... 7.3MB

    https://ntp.niehs.nih.gov/go/tr385

    ... d-Carvone Furfural 355 356 357 358 359 360 361 Diphenhydramine Hydrochloride Furosemide Hydrochlorothiazide Ochratoxin A 8-Methoxypsoralen N,N-Dimethylaniline ...

  43. TR-388: Ethylene Thiourea (CASRN 96-45-7) in F344 Rats and B6C3F1Mice... 13.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr388.pdf

    ... Epinephrine Hydrochloride d-Cawone Furfural 355 356 Diphenhydramine Hydrochloride Furosemide 386 387 Tetranitromethane Amphetamine Sulfate 357 358 Hydrochlorothiazide Ochratoxin ...

  44. TR-390: 3,3'-Dimethylbenzidine Dihydrochloride (CASRN 612-82... 12.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr390.pdf

    ... 378 Benzaldehyde 355 Diphenhydramine Hydrochloride 379 2-Chloroacetophenone 356 Furosemide 380 Epinephrine Hydrochloride 357 Hydrochlorothiazide 381 d-Carvone 358 Ochratoxin A ...

  45. TR-394: Acetaminophen (CASRN 103-90-2) in F344 Rats and B6C3F1Mice... 14.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr394.pdf

    ... and Chloraminated Water 355 Diphenhydramine Hydrochloride 393 Sodium Fluoride 356 Furosemide 395 Probenecid 357 Hydrochlorothiazide 3% Monochloroacetic Acid 358 Ochratoxin A 397 ...

  46. TR-395: Probenecid (CASRN 57-66-9) in F344/N Rats and B6C3F1Mice... 16.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr395.pdf

    ... 355 Diphenhydramine Hydrochloride 380 Epinephrine Hydrochloride 356 Furosemide 381 d-Carvone 357 Hydrochlorothiazide 382 Furfural 358 Ochratoxin A 386 ...

  47. TR-397: C.I. Direct Blue 15 (CASRN 2429-74-5) in F344 Rats (Drinking... 13.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr397.pdf

    ...3'-Dimethoxybenzidine Dihydrochhide 358 357 356 355 Ochratoxin A Hydrochlorothiazide Furosemide Diphenhydramine Hydrochloride 393 392 391 390 Sodium Fluoride Chlorinated Water and ...

  48. TR-405: C.I. Acid Red 114 (CASRN 6459-94-5) in F344/N Rats (Drinking... 12.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr405.pdf

    ... 353 2,4-Dichlorophenol 354 Dimethoxane 355 Diphenhydramine Hydrochloride 356 Furosemide 357 Hydrochlorothiazide 358 Ochratoxin A 359 8-Methcorypsoralen 360 ...

  49. TR-408: Mercuric Chloride (CASRN 7487-94-7) in F344 Rats and... 12.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr408.pdf

    ... N-Methylolacrylamide 2,4-Dichlorophenol Dimethoxane Diphenhydramine Hydrochloride Furosemide Hydrochlorothiazide Ochratoxin A 8-Methaxypsoralen N,N-Dimethylaniline ...

  50. TR-414: Pentachloroanisole (CASRN 1825-21-4) in F344 Rats and... 15.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr414.pdf

    ... Dimethoxane 394 Acetaminophen 355 Diphenhydramine Hydrochloride 395 Probenecid 356 Furosemide 3% Monuchloroacetic Acid 357 Hydmhlorothiazide 397 C.I. Direct Blue IS 358 ...

 
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