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GMM-02: Genetically Modified Model Report on Acesulfame Potassium... 2.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm02_508.pdf
ToxiciTy STudieS of aceSulfaMe PoTaSSiuM (caSRN 55589-62-3) iN fVB/N-TGN(V-ha-RaS)led ... OF ACESULFAME POTASSIUM (CAS NO. 55589-62-3) IN FVB/N-TgN(v-Ha-ras)Led (Tg.AC) ...
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TOX-11: Antimony Potassium Tartrate (CASRN 28300-74-5) 2.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox011.pdf
N N N NT T T TP P P P R R R RE E E EP P P PO O O OR R R RT T T T O O O ON N N N T T T TH H H HE E E E T T T TO O O OX X X XI I I IC C C CI I I IT T T TY Y Y Y S S S ST T T TU U U ...
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TOX-96: Toxicity Studies of Perfluoroalkyl Sulfonates (Perfluorobutane... 6.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox096_508.pdf
SulfoNaTeS (PeRfluoRobuTaNe SulfoNic acid, PeRfluoRohexaNe SulfoNaTe PoTaSSium SalT, aNd PeRfluoRoocTaNe SulfoNic acid) admiNiSTeRed by GavaGe To SPRaGue dawley (hSd:SPRaGue dawley ...
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Transgenic Model Evaluation II (Acesulfame Potassium): Target... 58KB
https://ntp.niehs.nih.gov/data/gmm/gmm02levels
Toxicity Studies of Acesulfame Potassium (CASRN 55589-62-3) in FVB/N-TgN(v-Ha-ras)Led ... evaluation II (Acesulfame potassium) 55589-62-3 05/22/2003 Dosed-Feed 0, 0.3, 1, or 3%; ...
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Abstract for GMM-2 64KB
https://ntp.niehs.nih.gov/publications/reports/gmm/gmm02
CASRN: 55589-62-3 Chemical Formula: C4H4KNO4S Molecular Weight: 201.25 Synonyms/Common Names: ASK; HOE-095K; 6-methyl-1,2,3-oxathiazine-4(3-H)-one-2,2-dioxide potassium salt Report ...
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Abstract for TOX-11 62KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox011
1abs Abstract for TOX-11 Toxicity Studies of Antimony Potassium Tartrate in F344/N Rats and B6C3F1 Mice (Drinking Water and Intraperitoneal Injection Studies) CASRN: 28300-74-5 ...
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Abstract for RACB95001 59KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb95001
1abs Abstract for RACB95001 Reproductive Toxicity of Potassium Dichromate (Hexavalent) Administered in Diet to SD Rats CASRN: 7778-50-9 Chemical Formula: Cr2H2O7.2K Molecular ...
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Abstract for RACB95002 60KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb95002
2abs Abstract for RACB95002 Reproductive Toxicity (Testicular) of Potassium Dichromate (Hexavalent) Administered in Diet to BALB/c Mice CASRN: 7778-50-9 Chemical Formula: ...
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Abstract for RACB94014 61KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb94014
4abs Abstract for RACB94014 Reproductive Toxicity of Potassium Dichromate (Hexavalent) (CAS 7778-50-9) Administered in Diet to BALB/c Mice CASRN: 7778-50-9 Chemical Formula: ...
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Abstract for TR-420 72KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr420
0abs Abstract for TR-420 Toxicology and Carcinogenesis Studies of Triamterene in F344/N Rats and B6C3F1 Mice (Feed Studies) CASRN: 396-01-0 Chemical Formula: C12H11N7 Molecular ...
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GMM-02: PATHOLOGY TABLES AND CURVES 60KB
https://ntp.niehs.nih.gov/data/tables/gmm/gmm02
9150 GMM-02: PATHOLOGY TABLES AND CURVES GMM-02 - Transgenic Model Evaluation II (Acesulfame Potassium) Pathology Tables - TG.AC P02 - Incidence Rates of Neoplastic by Anatomic ...
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Monograph: Antimony Trioxide; Appendices; Aug. 15, 2018 1.6MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/january/antimonydraftmonograph_appendices_revised.pdf
Revised Draft Report on Carcinogens Monograph on Antimony Trioxide: Appendices August 15, 2018 Office of the Report on Carcinogens Division of the National Toxicology Program ...
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Monograph: Antimony Trioxide; Appendices; Nov. 29, 2017 1.2MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/january/antimonydraftmonograph_appendices.pdf
Draft Report on Carcinogens Monograph on Antimony Trioxide: Appendices Peer-Review Draft November 29, 2017 Office of the Report on Carcinogens Division of the National Toxicology ...
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GMM-06: Genetically Modified Model Report on Sodium Bromate ... 1.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm06_508.pdf
SodiuM BRoMaTe (caSRN 7789-38-0) iN GeNeTically Modified (fVB TG.ac heMizyGouS) Mice (deRMal aNd dRiNkiNG WaTeR STudieS) aNd caRciNoGeNiciTy STudieS of SodiuM BRoMaTe iN ...
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Minutes: BSC TRRS; May 22, 2003 842KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2003/may/trrs22may2003mins_508.pdf
... mice. 5 Acesulfame Potassium 55589-62-3. NEW02 Artificial sweetener ...... Richard Irwin Dr. Richard Storer 55589-62-3 Dr. David Malarkey Dr. Michael Elwell feed Dr. ...
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Abstract for TOX-96 85KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox096
96abs Abstract for TOX-96 Toxicity Studies of Perfluoroalkyl Sulfonates Administered by Gavage to Sprague Dawley (Hsd:Sprague Dawley SD) Rats (Revised) Substances: Perfluorobutane ...
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RoC Profile: Chromium Hexavalent Compounds; 15th RoC 2021 174KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/chromiumhexavalentcompounds.pdf
Chromium Hexavalent Compounds CAS No. 18540-29-9 Known to be human carcinogens First listed in the First Annual Report on Carcinogens (1980) Carcinogenicity Chromium hexavalent ...
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RoC Monograph: Antimony Trioxide; October 2018 2.6MB
https://ntp.niehs.nih.gov/ntp/roc/monographs/antimony_final20181019_508.pdf
RepoRt on CaRCinogens MonogRaph on antiMony tRioxide ROC MONOGRAPH 13 OCTOBER 2018 Report on Carcinogens Monograph on Antimony Trioxide RoC Monograph 13 October 2018 National ...
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Japanese Minimum Requirements for Biological Products 2.0MB
https://ntp.niehs.nih.gov/iccvam/methods/biologics/vaccine/japan-minreqs.pdf
MINIMUM REQUIREMENTS FOR BIOLOGICAL PRODUCTS National Institute of Infectious Diseases Japan, 2006 - 1 - MINIMUM REQUIREMENTS FOR BIOLOGICAL PRODUCTS Notice: This English version ...
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Abstract for GMM-6 79KB
https://ntp.niehs.nih.gov/publications/reports/gmm/gmm06
6abs Abstract for GMM-6 Toxicology Studies of Sodium Bromate in Genetically Modified (FVB Tg.AC Hemizygous) Mice (Dermal and Drinking Water Studies) and Carcinogenicity Studies of ...
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Abstract for TOX-80 65KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox080
0abs Abstract for TOX-80 Toxicity Studies of Sodium Thioglycolate Administered Dermally to F344/N Rats and B6C3F1/N Mice CASRN: 367-51-1 Chemical Formula: C2H4O2S.Na Molecular ...
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RoC Background Document: Nickel Compounds; Dec. 2-3, 1998 6.7MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/nickelcompds1_oneapp_508.pdf
NICKEL COMPOUNDS FINAL MARCH 1999 Prepared for the December 2-3, 1998, Meeting of the Report on Carcinogens Subcommittee of the NTP Board of Scientific Counselors Prepared by ...
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Mechanistic and Other Relevant Data; Amy Wang; RoC; Jan. 24,... 1.5MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/january/presentations/mechanistic_508.pdf
Mechanistic and Other Relevant Data Amy Wang, PhD Office of the Report on Carcinogens National Institute of Environmental Health Sciences January 24, 2018 Draft RoC Monograph on ...
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Per- and Polyfluoroalkyl Substances (PFAS) 80KB
https://ntp.niehs.nih.gov/whatwestudy/topics/pfas
PFAS Per- and Polyfluoroalkyl Substances (PFAS) The revised reports TR-598, TOX-96, and TOX-97 are now available. Person filling glass with water from a faucet Research Overview ...
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Abstract for TR-336 64KB
https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr336
6abs Abstract for TR-336 Toxicology and Carcinogenesis Studies of Penicillin VK in F344/N Rats and B6C3F1 Mice (Gavage Studies) CASRN: 132-98-9 Chemical Formula: C16H17KN2O5S ...
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TR-420: Triamterene (CASRN 396-01-0) in F344/N Rats and B6C3F1Mice... 20.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr420.pdf
Program (NTP) is made up of four charter agencies o f the U.S. Department of Health and Human Services (DHHS): the National Cancer Institute (NCI), National Institutes o f Health; ...
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TR-336: Penicillin VK (CASRN 132-98-9) in F344/N Rats and B6C3F1Mice... 9.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr336.pdf
PROGRAM Technical Report Series No. 336 1,1 K * ' t I " * cs TOXICOLOGY AND CARCINOGENESIS STUDIES OF PENICILLIN VK (CAS NO. 132-98-9) IN F344/N RATS AND B6C3Fi MICE (GAVAGE ...
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RoC Profile: Arsenic and Inorganic Arsenic Compounds; 15th RoC... 152KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/arsenic.pdf
Arsenic and Inorganic Arsenic Compounds CAS No. 7440-38-2 (Arsenic) No separate CAS No. assigned for inorganic arsenic compounds Known to be human carcinogens First listed in the ...
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TOX-72: Sodium Dichromate Dihydrate (CASRN 7789-12-0) 14.9MB
https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox072.pdf
72 NTP Technical Report on the Toxicity Studies of Sodium Dichromate Dihydrate (CAS No. 7789-12-0) Administered in Drinking Water to Male and Female F344/N Rats and B6C3F 1 Mice ...
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Abstract for TR-115 62KB
https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr115
5abs Abstract for TR-115 Bioassay of Sulfallate for Possible Carcinogenicity CASRN: 95-06-7 Chemical Formula: C8H14Cl N S2 Molecular Weight: 95-06-7 Synonyms/Common Names: ...
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RoC Background Document: Saccharin; Oct. 30-31, 1997 8.9MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/saccharin1_3apps_508.pdf
BACKGROUND DOCUMENT for SACCHARIN FINAL MARCH 1999 Prepared for the October 30-31, 1997, Meeting of the Report on Carcinogens Subcommittee of the NTP Board of Scientific Counselors ...
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Antimony Draft Monograph; Nov. 29, 2017 3.5MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/january/antimonydraftmonograph.pdf
Draft Report on Carcinogens Monograph on Antimony Trioxide Peer-Review Draft November 29, 2017 Office of the Report on Carcinogens Division of the National Toxicology Program ...
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Historical Controls: Pathology Tables by All Routes/Vehicles... 224KB
https://ntp.niehs.nih.gov/ntp/historical_controls/historicalratesgmm_508.pdf
Historical control rates for NTP Tg.AC and p53 mice G. E. Kissling 1/31/08 Tg.AC Females, 6 months Trimethlolpropane triacrylate Pentaerythritol triacrylate Bromodichloromethane ...
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Abstract for TOX-97 125KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox097
7abs Abstract for TOX-97 Toxicity Studies of Perfluoroalkyl Carboxylates Administered by Gavage to Hsd: Sprague Dawley SD Rats (Revised) Substances: Perfluorohexanoic acid (CASRN ...
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Agenda: BSC TRRS; May 22, 2003 89KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2003/may/trrs22may2003agenda_508.pdf
John French transgenic mouse models for short-term cancer bioassays Aspartame 22839-47-0 GMM 1 artificial sweetener feed p53 mice Acesulfame K GMM 2 artificial sweetener 55589-62-3 ...
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Antimony Draft Monograph (Revised); Aug. 15, 2018 2.8MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/january/antimonydraftmonograph_revised.pdf
Revised Draft: Report on Carcinogens Monograph on Antimony Trioxide August 15, 2018 Office of the Report on Carcinogens Division of the National Toxicology Program National ...
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National Toxicology Program Toxicity Report Series 590KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox037.pdf
7 NTP Technical Report on Toxicity Studies of Sodium Cyanide (CAS No. 143-33-9) Administered in Drinking Water to F344/N Rats and B6C3F 1 Mice Charles D. Hébert, Ph.D., Study ...
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TR-546: Sodium Dichromate Dihydrate (CASRN 7789-12-0) in F344... 8.9MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr546.pdf
TOXICOLOGY AND CARCINOGENESIS STUDIES OF SODIUM DICHROMATE DIHYDRATE (CAS NO. 7789-12-0) IN F344/N RATS AND B6C3F1 MICE (DRINKING WATER STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. ...
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TOX-74: Cellulose Insulation 7.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox074_rev.pdf
4 NTP Toxicity Study Report on the Atmospheric Characterization, Particle Size, Chemical Composition, and Workplace Exposure Assessment of Cellulose Insulation (CELLULOSEINS) ...
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RoC Profile: Antimony Trioxide; 15th RoC 2021 197KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/antimony.pdf
Report on Carcinogens, Fifteenth Edition National Toxicology Program, Department of Health and Human Services For Table of Contents, see home page: http://ntp.niehs.nih.gov/go/roc ...
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Reproductive Abstracts 202KB
https://ntp.niehs.nih.gov/publications/abstracts/repro
RACB93156 Pentamidine Isethionate Reproductive, Developmental and General Toxicity Study of Pentamidine Isethionate (CASRN: 140-64-7) in Swiss Mice 1993 Reproductive RDGT97002 ...
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Short-Term Toxicity Reports 224KB
https://ntp.niehs.nih.gov/publications/reports/tox
TOX-106 PDF (2.68 MB) Toxicity Studies of Sodium Metavanadate (CASRN 13718-26-8) and Vanadyl Sulfate (CASRN 27774-13-6) Administered in Drinking Water to Sprague Dawley ...
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ICCVAM Test Method Evaluation Report on the LLNA: DA 30.4MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-da/tmer.pdf
ICCVAM Test Method Evaluation Report on the Murine Local Lymph Node Assay: DA A Nonradioactive Alternative Test Method to Assess the Allergic Contact Dermatitis Potential of ...
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Study Abstracts 375KB
https://ntp.niehs.nih.gov/publications/abstracts
RDGT94003 Chlordibromomethane Short-Term Reproductive Developmental Toxicity of Chlorodibromomethane (CASRN: 124-48-1) Administered in Drinking Water to Sprague Dawley Rats 1996 ...
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ICCVAM Test Method Evaluation Report on the Reduced LLNA 21.6MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ld/tmer.pdf
ICCVAM Test Method Evaluation Report The Reduced Murine Local Lymph Node Assay: An Alternative Test Method Using Fewer Animals to Assess the Allergic Contact Dermatitis Potential ...
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Presentation: The Many Faces of Pertussis Toxin: Workshop on... 1.0MB
https://ntp.niehs.nih.gov/iccvam/meetings/histwksp-2012/present/carbonetti-508.pdf
The Many Faces of Pertussis Toxin Nicholas Carbonetti, PhD University of Maryland Medical School NICEATM-ICCVAM HIST Workshop, November 2012 Historical names . Histamine ...
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RoC Profile: Tetranitromethane; 15th RoC 2021 125KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/tetranitromethane.pdf
Tetranitromethane CAS No. 509-14-8 Reasonably anticipated to be a human carcinogen First listed in the Seventh Annual Report on Carcinogens (1994) NO 2 C O 2 N NO 2 O 2 N ...
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TR-227: Gum Arabic (CASRN 9000-01-5) in F344 Rats and B6C3F1Mice... 4.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr227.pdf
7 CARCINOGENESIS BIOASSAY OF GUM ARABIC (CAS NO. 9000-01-5) IN F344 RATS AND B6C3F1 MICE (FEED STUDY) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service National ...
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Abstract for TOX-74 66KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox074
4abs Abstract for TOX-74 Toxicity Study Report on the Atmospheric Characterization, Particle Size, Chemical Composition, and Workplace Exposure Assessment of Cellulose Insulation ...
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In Vitro Cardiotoxicity Screening Approaches 63KB
https://ntp.niehs.nih.gov/whatwestudy/niceatm/test-method-evaluations/cardio
cardio In Vitro Cardiotoxicity Screening Approaches Cardiotoxicity, or toxicity to the heart, is a major cause of failure of new drugs in mid- to late-stage development. Most ...
