-
TR-338: Erythromycin Stearate (CASRN 643-22-1) in F344/N Rats... 10.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr338.pdf
8 TOXICOLOGY AND CARCINOGENESIS STUDIES OF ERYTHROMYCIN STEARATE (CAS NO. 643-22-1) IN F344/N RATS AND B6C3F1 MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES ...
-
Abstract for TR-338 65KB
https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr338
8abs Abstract for TR-338 Toxicology and Carcinogenesis Studies of Erythromycin Stearate in F344/N Rats and B6C3F1 Mice (Feed Studies) CASRN: 643-22-1 Chemical Formula: C37H67NO13 ...
-
Target Organs and Levels of Evidence for TR-338 57KB
https://ntp.niehs.nih.gov/data/tr/300s/tr338levels
2 Target Organs and Levels of Evidence for TR-338 Toxicology and Carcinogenesis Studies of Erythromycin Stearate (CASRN 643-22-1) in F344/N Rats and B6C3F1 Mice (Feed Studies) ...
-
Minutes: BSC TRRS; July 14, 1987 821KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1987/july/87july14trrsmin_508.pdf
/9.2 - Board of Scientific Counselors National Toxicology Progra m Summary Minutes fro m Peer Reviews of Draft Technical Reports of Long-Term Toxicology and Carcinogenesis Studies ...
-
RoC Background Document: Cadmium; Oct. 30-31, 1997 13.0MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/cadmium_508.pdf
CADMIUM FINAL MARCH 1999 Prepared for the October 30-31, 1997, Meeting of the Report on Carcinogens Subcommittee of the NTP Board of Scientific Counselors Prepared by Integrated ...
-
RoC Profile: Cobalt-Related Exposures; 15th RoC 2021 409KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/cobalt.pdf
Genomic stability Oxidative damage Hypoxia-responsive target genes Resistance to apoptosis Accumulation of critical mutations Dysregulation of cell growth and proliferation Tumor ...
-
RoC Profile: Lead and Lead Compounds; 15th RoC 2021 190KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/lead.pdf
Lead and Lead Compounds CAS No. 7439-92-1 (Lead) No separate CAS No. assigned for lead compounds as a class Reasonably anticipated to be human carcinogens First listed in the ...
-
Revised Draft RoC Monograph Cobalt: RoC Peer Review; July 22... 3.0MB
https://ntp.niehs.nih.gov/ntp/roc/draftmono/revised_cobalt.pdf
Monograph on Cobalt and Cobalt Compounds That Release Cobalt Ions In Vivo November 6, 2015 Office of the Report on Carcinogens Division of the National Toxicology Program National ...
-
Cobalt Literature Search StrategyRoC Peer Review; July 22, 2015 374KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_litsearchstrategy_508.pdf
Literature Search Strategy for Preparing the Report on Carcinogens Monograph on Cobalt and Certain Cobalt Compounds Introduction and objective The objective of the literature ...
-
TR-591: TRIM VX in Wistar Han [Crl:WI (Han)] Rats and B6C3F1... 7.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr591_508.pdf
sTudies of TRiM ® Vx iN WisTaR haN [cRl:Wi(haN)] RaTs aNd B6c3f1/N Mice (iNhalaTioN sTudies) NTP TR 591 NOVEMBER 2016 NTP Technical Report on the Toxicology and Carcinogenesis ...
-
RoC Profile: Cadmium and Cadmium Compounds; 15th RoC 2021 162KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/cadmium.pdf
Cadmium and Cadmium Compounds CAS No. 7440-43-9 (Cadmium) No separate CAS No. assigned for cadmium compounds as a class Known to be human carcinogens First listed in the First ...
-
RoC Monograph: Cobalt and Cobalt Compounds; April 2016 3.5MB
https://ntp.niehs.nih.gov/ntp/roc/monographs/cobalt_final_508.pdf
Cobalt and Cobalt CoMpounds that Release Cobalt ions in ViVo ROC MONOGRAPH 06 APRIL 2016 Report on Carcinogens Monograph on Cobalt and Cobalt Compounds That Release Cobalt Ions In ...
-
RoC Background Document for Lead and Lead Compounds - May 8,... 3.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/lead-public_508.pdf
FINAL Report on Carcinogens Background Document for Lead and Lead Compounds May 8, 2003 Prepared for the: U.S. Department of Health and Human Services Public Health Service ...
-
CERHR Monograph: Methylphenidate 11.6MB
https://ntp.niehs.nih.gov/ntp/ohat/stimulants/methylphenidate/methylphenidatemonograph.pdf
Methylphenidate August 2005 NIH Publication No. 05 - 4473 iii Table of ConTenTs Preface......
-
Draft RoC Monograph Cobalt: RoC Peer Review; July 22, 2015 2.8MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_draftmonograph.pdf
Cobalt and Certain Cobalt Compounds June 5, 2015 Office of the Report on Carcinogens Division of the National Toxicology Program National Institute of Environmental Health ...
-
Nomination Background: d-Pseudoephedrine (CASRN: 90-82-4) 388KB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/ephedrinealkaloids_508.pdf
SUMMARY OF DATA FOR CHEMICAL SELECTION Dietary Supplements Containing Ephedrine Alkaloids BASIS OF NOMINATION Dietary supplements containing ephedrine alkaloids from herbal ...
-
TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB
https://ntp.niehs.nih.gov/go/tr518
THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF TRIETHANOLAMINE (CAS NO. 102-71-6) IN B6C3F 1 MICE (DERMAL STUDY) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC ...
-
TR-368: Nalidixic Acid (CASRN 389-08-2) in F344/N Rats and B6C3F1Mice... 13.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr368.pdf
PROGRAM Technical Report Series No. 368 *<»vdia TOXICOLOGY AND CARCINOGENESIS STUDIES OF NALIDIXIC ACID (CAS NO. 389-08-2) IN F344/N RATS AND B6C3Fi MICE (FEED STUDIES) U.S. ...
-
CERHR Monograph: Amphetamines 4.1MB
https://ntp.niehs.nih.gov/ntp/ohat/stimulants/amphetamines/amphetaminemonograph.pdf
Amphetamines July 2005 NIH Publication No. 05 - 4474 iii Table of Contents Preface......
-
CERHR Monograph: Potential Human Reproductive and Developmental... 1.4MB
https://ntp.niehs.nih.gov/ntp/ohat/egpg/propylene/pg_monograph.pdf
NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Propylene Glycol March 2004 NIH Publication No. 04-4482 iii Table of Contents Preface ...
-
Monograph on Potential Human Reproductive and Developmental Effects... 2.4MB
https://ntp.niehs.nih.gov/ntp/ohat/fluoxetine/fluoxetine_monograph.pdf
NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Fluoxetine November 2004 NIH Publication No. 05 - 4471 iii Table of Contents Preface ...
-
TR-484: 2-Butoxyethanol (CASRN 111-76-2) in F344/N Rats and B6C3F1Mice... 11.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr484.pdf
2-BUTOXYETHANOL (CAS NO. 111-76-2) IN F344/N RATS AND B6C3F 1 MICE (INHALATION STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 March 2000 NTP ...
-
TR592: Dietary Zinc (CASRN 5263-02-5) In Sprague Dawley Rats... 2.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr592_508.pdf
oN The Toxicology aNd caRciNogeNesis sTudy of dieTaRy ZiNc (casRN 5263-02-5) iN sPRague dawley (hsd:sPRague dawley ® sd ® ) RaTs (feed sTudy) NTP TR 592 JANUARY 2019 NTP ...
-
RR-11: The Chemical and Physical Characterization of Recycled... 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr11_508.pdf
The chemical aNd Physical chaRacTeRizaTioN of Recycled TiRe cRumb RubbeR NTP RR 11 JULY 2019 NTP Research Report on the Chemical and Physical Characterization of Recycled Tire ...
-
NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
9433 Conclusion by Sex/Species Report No. Peer Review Date/Target Organs Substance Name CASRN Male Rats Female Rats Male Mice Female Mice TR-603 01/01/23 Black Cohosh 84776-26-1 NE ...
-
Minutes: BSC TRRS; Jun 27, 1989 1.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1989/june/89jun27trrsmins_508.pdf
of Scientific Counselors National Toxicology Program Summary Minutes from Peer Reviews of Draft Technical Reports of Long-Term Toxicology and Carcinogenesis Studies and Short-Term ...
-
Technical Reports 903KB
https://ntp.niehs.nih.gov/publications/reports/tr
TR-603 PDF (3.02 MB) Toxicology and Carcinogenesis Studies of Black Cohosh Root Extract (CASRN 84776-26-1) Administered by Gavage to Sprague Dawley (Hsd:Sprague Dawley SD) Rats and ...
-
CERHR Monograph: Hydroxyurea 3.6MB
https://ntp.niehs.nih.gov/ntp/ohat/hydroxyurea/humonograph20090401.pdf
National Toxicology Program U.S. Department of Health and Human Services Center for The Evaluation of Risks To Human Reproduction NTP-CERHR MoNogRaPH oN THE PoTENTial HuMaN ...
-
Study Reports 1.1MB
https://ntp.niehs.nih.gov/publications/reports
750897 About Technical Reports Long-term NTP toxicology and carcinogenicity studies usually involve exposing laboratory animals (rats and mice) to a substance for a period of two ...
-
TR-449: Triethanolamine (CASRN 102-71-6) in F344 Rats and B6C3F1Mice... 10.1MB
https://ntp.niehs.nih.gov/go/tr449
NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF TRIETHANOLAMINE (CAS NO. 102-71-6) IN F344/N RATS AND B6C3F MICE 1 (DERMAL STUDIES) NATIONAL TOXICOLOGY PROGRAM ...
-
Toxicology/Carcinogenicity 1.1MB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox
ba Toxicology/Carcinogenicity Female scientist looking through a microscope in a laboratory Study Overview Study: Short-term toxicity, long-term carcinogenicity Species: Rats, mice ...
-
NTP Monograph on Health Effects of Low-Level Lead Appendix B... 873KB
https://ntp.niehs.nih.gov/ntp/ohat/lead/final/leadappendixb_final_508.pdf
B: HUMAN STUDIES OF IMMUNE EFFECTS OF LEAD CONSIDERED IN DEVELOPING CONCLUSIONS Appendix B: Human Studies of Immune Effects of Pb Considered in Developing Conclusions NTP Monograph ...
-
RoC Background Document: Beryllium Compounds; Dec. 16-17, 1999 5.3MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/be_no_appendices_508.pdf
FINAL Report on Carcinogens Background Document for Beryllium and Beryllium Compounds December 16 - 17, 1999 Meeting of the NTP Board of Scientific Counselors Report on ...
-
TR-213: Butyl Benzyl Phthalate (CASRN 85-68-7) in F344/N Rats... 4.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr213.pdf
NATIpNAL TOXICOLOGY PROGRAM Technical Report Series No. 213 CARCINOGENESIS BIOASSAY OF BUTYL BENZYL PHTHALATE (CAS NO. 85-68-7) IN F344/N RATS AND BGCSFj MICE (FEED STUDY) U.S. ...
-
TR-370: Benzofuran (CASRN 271-89-6) in F344/N Rats and B6C3F1Mice... 12.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr370.pdf
70 TOXICOLOGY AND CARCINOGENESIS STUDIES OF BENZOFURAN (CAS NO. 271-89-6) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health ...
-
TR-586: CIMSTAR 3800 in F344/NTac Rats and B6C3F1/N Mice and... 2.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr586_508.pdf
NTP TECHNICAL REPORT ON THE TOXICOLOGY STUDIES OF CIMSTAR 3800 IN F344/NTAC RATS AND B6C3F1/N MICE AND TOXICOLOGY AND CARCINOGENESIS STUDIES OF CIMSTAR 3800 IN WISTAR HAN ...
-
ICCVAM Report: Corrositex: An In Vitro Method for Assessing Dermal... 5.1MB
https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/corprrep.pdf
i Corrositex ® : An In Vitro Test Method for Assessing Dermal Corrosivity Potential of Chemicals The Results of an Independent Peer Review Evaluation Coordinated by the ...
-
TR-415: Polysorbate 80 (CASRN 9005-65-6) in F344/N Rats and B6C3F1Mice... 12.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr415.pdf
FOREWORD The National Toxicology Program ( N T P ) is made up o f four charter agencies of the U.S. Department o f Health and Humin Services (DHHS): the National Cancer Institute ...
-
ICCVAM Test Method Evaluation Report: In Vitro Test Methods for... 42.0MB
https://ntp.niehs.nih.gov/iccvam/docs/ocutox_docs/invitro-2010/tmer-vol1.pdf
ICCVAM Test Method Evaluation Report: Current Validation Status of In Vitro Test Methods Proposed for Identifying Eye Injury Hazard Potential of Chemicals and Products Interagency ...
-
Draft TR-600: Di-n-butyl Phthalate (CASRN 84-74-2) Administered... 2.0MB
https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/april/tr600_508.pdf
Di-n-butyl Phthalate (CASRN 84-74-2) 3 Administered in Feed to Sprague Dawley 4 (Hsd:Sprague Dawley ® SD ® ) Rats 5 and B6C3F1/N Mice 6 Technical Report 600 7 February 2021 8 ...
-
TR-600: Di-n-butyl Phthalate Administered in Feed to Sprague... 3.4MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr600_508.pdf
di-N-buTyl PhThalaTe (casRN 84-74-2) admiNisTeRed iN feed To sPRague dawley (hsd:sPRague dawley ® sd ® ) RaTs aNd b6c3f1/N mice NTP TR 600 NOVEMBER 2021 NTP Technical Report on ...
-
TR-417: p-Nitrophenol (CASRN 100-02-7) in Swiss Webster Mice... 7.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr417.pdf
FOREWORD The National Toxicology Program (NTP)is made up o f four charter agencies of the U.S. Department of Health and Human Services (DHHS): the National Cancer Institute (NCI), ...
-
TR-444: Initiation/Promotion Study of o-Benzyl-p-Chlorophenol... 6.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr444.pdf
NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 444 ONE-YEAR INITIATION/PROMOTION STUDY OF O-BENZYL-p-CHLOROPHENOL (CAS NO. 120-32-1) IN SWISS (CD-l@) MICE (MOUSE SKIN ...
-
TOX-30: Dibutyl Phthalate (CASRN 84-74-2) 3.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox030.pdf
0 NTP Technical Report on Toxicity Studies of Dibutyl Phthalate (CAS No. 84-74-2) Administered in Feed to F344/N Rats and B6C3F Mice 1 Daniel S. Marsman, D.V.M., Ph.D., Study ...
-
TR-389: Sodium Azide (CASRN 26628-22-8) in F344 Rats (Gavage... 8.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr389.pdf
89 TOXICOLOGY AND CARCINOGENESIS STUDIES OF SODIUM AZIDE (CAS NO. 26628-22-8) IN F344/N RATS (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service ...
-
TR-410: Naphthalene (CASRN 91-20-3) in B6C3F1Mice (Inhalation... 8.6MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr410.pdf
TOXICOLOGY PROGRAM Technical Report Series No. 410 TOXICOLOGY AND CARCINOGENESIS STUDIES OF NAPHTHALENE (CAS NO. 91-20-3) IN B6C3Fl MICE (INHALATION STUDIES) U . S . DEPARTMENT OF ...
-
TR-278: 2,6-Xylidine (2,6-Dimethylaniline) (CASRN 87-62-7) in... 9.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr278.pdf
8 TOXICOLOGY AND CARCINOGENESIS STUDIES OF 2,6=XYLIDINE (2,6-DIMETHY LANILINE) (CAS NO. 87-62-7) IN CHARLES RIVER CD RATS (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN ...
-
TR-359: 8-Methoxypsoralen (CASRN 298-81-7) in F344/N Rats (Gavage... 7.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr359.pdf
NQ. 359 TOXICOLOGY AND CARCINOGENESIS STUDIES OF 8-METHOXYPSORALEN (CAS NO. 298-81-7) IN F344/N RATS (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health ...
-
TR-399: Titanocene Dichloride (CASRN 1271-19-8) in F344/N Rats... 8.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr399.pdf
399 TOXICOLOGY AND CARCINOGENESIS STUDIES OF TITANOCENEDICHLORIDE (CAS NO. 1271-19-8) IN F344/N RATS (GAVAGESTUDIES) U.S.DEPARTMENT OF HEALTHANDHUMANSERVICES Public Health Service ...
-
TR-413: Ethylene Glycol (CASRN 107-21-1) in B6C3F1Mice (Feed... 11.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr413.pdf
I FOREWORD The National Toxicology Program (NTP) is made up of four charter agencies o f the US. Department o f Health and Human Services (DHHS): the National Cancer Institute ...