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Search suggestions for "56-40-6".

  1. CEBS Data Related to Glycine (56-40-6) https://cebs.niehs.nih.gov/cebs/test_article/56-40-6


378 results found for "56-40-6".

  1. Abstract for TOX-16 61KB

    https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox016

    CASRN: 1071-83-6 Chemical Formula: C3H8NO5P Molecular Weight: 169.1 Synonyms/Common Names: Glyphosate, technical grade; glycine, N-(phosphonomethyl); N-phosphono-methyl glycine; ...

  2. TOX-16: Glyphosate (CASRN 1071-83-6) 1.9MB

    https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox016.pdf

    ... Weight: 169.1 Synonyms: Glyphosate, technical grade; Glycine, N-(phosphonomethyl); N-phosphono- methyl glycine; N-(phosphonomethyl)glycine; MON 0573; MON 2139. ABSTRACT ...

  3. TR-554: 5-(Hydroxymethyl)-2-furfural (CASRN 67-47-0) in F344... 7.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr554.pdf

    ... furoic acid metabolite was 20- to 30-fold greater than the glycine conjugate; however, administration of 3 g of glycine prior to administration of 330 mg/kg 5-(hydroxy- ...

  4. Lung - Emphysema - Nonneoplastic Lesion Atlas 292KB

    https://ntp.niehs.nih.gov/atlas/nnl/respiratory-system/lung/Emphysema

    ... Pires KM, Bezerra FS, Machado MN, Zin WA, Porto LC, Valença SS. 2011. N-(2-mercaptopropionyl)-glycine but not allopurinol prevented cigarette smoke-induced alveolar enlargement in ...

  5. Stomach, Glandular Stomach, Epithelium - Hyperplasia 285KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/respiratory/lung/emphysem/lung-emphysema-508.pdf

    ... Thorax 57:908-914. Full-Text: http://thorax.bmj.com/content/57/10/908.full Pires KM, Bezerra FS, Machado MN, Zin WA, Porto LC, Valença SS. 2011. N-(2-mercaptopropionyl)- glycine ...

  6. TR-375: Vinyl Toluene (Mixed Isomers) (65%meta-isomer and 32... 20.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr375.pdf

    ... p-meth- ylmandelic acid (5.7%), p-methylphenylgly- oxylic acid (11.9%), p-methylbenzoyl glycine (9.3%), p-methylphenylacetyl glycine (2.5%), and p-vinylbenzoyl glycine (1 %). ...

  7. Slide 1 719KB

    https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-15444/stemina/sekowskiposter.pdf

    ... Figure 2. The glycine, serine, and threonine metabolism pathway also appears involved based on our data which showed that 5- aminolevulinic acid, choline and L-cystathionine were ...

  8. Development of a Rapid Risk Assessment Process and Software Tools... 3.5MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2022/ppt/18_clewell_508.pdf

    ... ligand binding to neurotransmitter receptors Neuro targets . Acetylcholine . AChE . AMPA . CHAT . GABA . Glutamate . Glycine . DRD2,3&4 . Kinate . PX2 . Serotonin Rahim et al. ...

  9. TR-382: Furfural (CASRN 98-01-1) in F344/N Rats and B6C3F1Mice... 11.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr382.pdf

    ... in each species is furoyl- glycine, suggesting that oxidation of furfural to furoic acid, followed by conjugation with glycine and excretion, is the major pathway of elimina- tion. ...

  10. TR-482: Furfural Alcohol (CASRN 98-00-0) in F344/N Rats and B6C3F1... 27.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr482.pdf

    ... is then further oxidized to furoic acid and conjugated with glycine to form furoylglycine. ... to was furanacryloylglycine, the glycine conjugate of furfural, which is then ...

  11. TR-378: Benzaldehyde (CASRN 100-52-7) in F344/N Rats and B6C3F1Mice... 14.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr378.pdf

    ... to benzoic acid, with subsequent glycine conjugation and excretion as hippuric ... that the predominant urinary metabolite (65%-70%) was the glycine conjugate hippuric acid. ...

  12. TR-572: Methyl trans-styryl ketone (CASRN 1896-62-4) in F344... 8.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr572_508.pdf

    ... These pathways produced the observed metabolites N-phenylacetyl-L-glycine, N-benzyl-L-glycine and N-acetyl-S-(4-phenyl-2-butanone)-L-cysteine. One oxi- dized metabolite, ...

  13. Minutes: BSC; March 13, 1990 1.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1990/march/19900313-14bsc_minutes_508be.pdf

    ... fractions from kidney but not from liver due to the activity of the enzyme gamma-glutamyl transpeptidase (GGT) with the cysteinyl glycine formed being the mutagenic species. ...

  14. TR-355: Diphenhydramine Hydrochloride (CASRN 147-24-0) in F344... 10.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr355.pdf

    ... glutamine in rhesus mon- keys or with glycine in dogs (Drach and Howell, 1968; Drach et ... p o x a n t h i n e , methotrexate, and glycine for 1 day, to thymi- dine, hypoxanthine, ...

  15. TR-498: p-Nitrotoluene (CASRN 99-99-0) in F344/N Rats and B6C3F1Mice... 10.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr498.pdf

    ... conjugation with glycine to form the hippuric acid, or nitro reduction and acylation. ... hypoxanthine, methotrexate, and glycine for 1 day; to medium containing ...

  16. Nomination Background: d-Pseudoephedrine (CASRN: 90-82-4) 388KB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/ephedrinealkaloids_508.pdf

    ... root, goldenseal, nettle leaf, gotu kola, spirulina, Royal jelly, citric acid, glycine, caffeine, croscarmellose sodium, protein hydrolysate, silica, modified cellulose, ...

  17. TR-578: Ginkgo biloba Extract (CASRN 90045-36-6) in F344/N Rats... 7.9MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr578_508.pdf

    ... receptors of the central nervous system, glycine, and GABA receptors (Kondratskaya et al., ... Structure-activity analysis of ginkgolide binding in the glycine receptor pore. J. ...

  18. TR-431: Benzyl Acetate (CASRN 140-11-4) in F344/N Rats and B6C3F1Mice... 15.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr431.pdf

    ... both gavage and dosed feed administration due to the depletion of the glycine supply pool. ... gavage and dosed feed adminis- tration due to the depletion o f the glycine supply pool. ...

  19. Draft ROC Monograph: Haloacetic Acids; June 6, 2017 3.1MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2017/july/haadraftmonograph.pdf

    ... detergents, food, and pharmaceuticals), glycine, thioglycolic acid, dyes, synthetic ... Glyoxylate can be further metabolized to glycolate, oxylate, glycine, and CO 2 (Figure ...

  20. Revised Draft ROC Monograph: Haloacetic Acids; Oct. 30, 2017 4.2MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2017/july/haadraftmonograph20171030.pdf

    ... detergents, food, and pharmaceuticals), glycine, thioglycolic acid, dyes, synthetic ... Glyoxylate can be further metabolized to glycolate, oxylate, glycine, and CO2 (Figure ...

  21. RoC Profile: Haloacetic Acids; 15th RoC 2021 382KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/haloacetic_acids.pdf

    ... For definitions of technical terms, see the Glossary. sults in formation of the metabolites glyoxylate, glycolate, oxylate, glycine, and carbon dioxide. The three trihaloacetic ...

  22. Genetic Toxicology 88KB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/genetic

    ... To limit random mutations, cultures were treated with thymidine, hypoxanthine, methotrexate, and glycine. Each culture contained 6 x 106 cells and 10 mL of medium dosed with the ...

  23. TR-343: Benzyl Alcohol (CASRN 100-51-6) in F344/N Rats and B6C3F1Mice... 8.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr343.pdf

    ... acid, which is conjugated with glycine and ex- creted as hippuric acid in the ... At lower doses, benzoic acid is then conjugated with glycine and excreted in the urine as ...

  24. Template Copyright 2014 © Clean Production Action 1.9MB

    https://ntp.niehs.nih.gov/ntp/ohat/publiccomms/2016/attachment-1.pdf

    ... This metabolite is further metabolized via glutathione conjugation and glycine conjugation. The second proposed metabolic pathway involves hydroxylation followed by elimination of ...

  25. CERHR Monograph: Potential Human Reproductive and Developmental... 4.3MB

    https://ntp.niehs.nih.gov/ntp/ohat/egpg/ethylene/eg_monograph.pdf

    ... Acid Acetate Formic Acid Oxalic Acid Glycine Malate CO 2 CO 2 Krebs Cycle O==C O Ca O ... is metabolized to formate and then respiratory CO 2 , and to urinary oxalate and glycine. ...

  26. CERHR Monograph: Amphetamines 4.1MB

    https://ntp.niehs.nih.gov/ntp/ohat/stimulants/amphetamines/amphetaminemonograph.pdf

    ...be.conjugated.with.glycine.to.form.hippuric.acid.(reviewed.in.(24, 31))..According.to.the. ... NH 2 CH 3 NH 2 CH 3 OH COOH Benzoic Acid Glycine NH 2 CH 3 HO NH 2 CH 3 HO OH N H COOH O ...

  27. TR-342: Dichlorvos (CASRN 62-73-7) in F344/N Rats and B6C3F1... 29.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr342.pdf

    ... acid, urea, carbon di- oxide, or other endogenous chemicals such as glycine and serine. ... administered dichlorvos is present as glycine, serine, and other nor- mal body ...

  28. TR-516: 2-Methylimidazole (CASRN 693-98-1) in F344/N Rats and... 9.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr516.pdf

    ... During cooking, 2-methylimidazole may be formed when ammonium hydroxide, glycine, and ... 8 Cystine 0.224 ± 0.012 0.210 - 0.240 8 Glycine 0.684 ± 0.041 0.620 - 0.740 8 Histidine ...

  29. TOX-82: 3-Month Estragole (CASRN 140-67-0) 3.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox082.pdf

    ... O-Demethylation Hydroxylation glucur onate, or glycine p-hydroxyallylbenzene estragole ... Hydroxylation Hydroxylation, then conjugation with sulfate, glucuronate, or glycine DNA ...

  30. TR-504: o-Nitrotoluene (CASRN 88-72-2) in F344/N Rats and B6C3F1... 14.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr504.pdf

    ... RTI, 1995, 1996a,b glycine to form the hippuric acid, or nitro reduc- tion and acylation. ... 8 Cystine 0.224 ± 0.012 0.210 - 0.240 8 Glycine 0.684 ± 0.041 0.620 - 0.740 8 Histidine ...

  31. TR-344: Tetracycline Hydrochloride (CASRN 64-75-5) in F344/N... 10.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr344.pdf

    ... con- stants, which indicate avidity similar to that of glycine for divalent metallic ions. ... 1.323 f 0.830 Cystine 0.310 f 0.099 Glycine 1.155 f 0.069 Histidine 0.572 f 0.030 ...

  32. TOX-26: Ethylene Glycol Ethers 2-Methoxyethanol, 2-Ethoxyethanol... 8.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox026.pdf

    ... The acid metabolites were found in the urine; in the case of 2-ethoxyethanol, some of the ethoxyacetic acid was conjugated with glycine to form N-ethoxyacetyl glycine (Jonsson et ...

  33. TOX-46: Hepathe Liver Carcinogen Methapyrilene Hydrochloride... 1.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox046.pdf

    ... San Francisco, CA) with Tris/glycine/SDS tank buffer at 10E C and 300 V for 30 minutes. ... hypoxanthine, methotrexate, and glycine for 1 day; to medium containing ...

  34. TOX-77: Hexachlorobenzene (CASRN 118-74-1) Administered by Gavage... 2.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox077_508.pdf

    ... further metabolized by cleavage of the glycine and glutamate residues resulting in ... 22 Cystine 0.220 ± 0.024 0.150-0.250 22 Glycine 0.701 ± 0.041 0.620-0.800 22 Histidine ...

  35. Workshop Report: Alternative Methods to Replace Animal Use for... 10.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/biologics-docs/bontwkshprept.pdf

    ... of a product from inside of the cell (e.g., 3 H-glycine, various neurotransmitters) . ... on dose response of inhibition of 3H glycine release following incubation with ...

  36. Background: Dimethylethanolamine (DMAE) [108-01-0] and Selected... 1.3MB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/dmae_update_110002_508.pdf

    ... Ethanolamine is methylated to choline, metabolized to form serine and glycine, and ... Ethanolamine is also methylated to choline and metabolized to form serine and glycine ...

  37. TR-537: Dibromoacetic Acid (CASRN 631-64-1) in F344/N Rats and... 9.3MB

    https://ntp.niehs.nih.gov/go/tr537

    ... Glyoxylate can undergo transamination to glycine, decarboxylation to form carbon dioxide, ... Cystine 0.223 ± 0.027 0.150 - 0.250 12 Glycine 0.702 ± 0.043 0.620 - 0.750 12 Histidine ...

  38. TR-549: Bromochloroacetic Acid (CAS 5589-96-8) in F344/N Rats... 20.0MB

    https://ntp.niehs.nih.gov/go/tr549

    ... Glyoxylate can undergo transamination to glycine, decarboxyla- tion to form carbon ... Cystine 0.225 ± 0.025 0.150 - 0.250 15 Glycine 0.701 ± 0.039 0.620 - 0.750 15 Histidine ...

  39. TR-442: p-Nitrobenzoic Acid (CASRN 62-23-7) in F344/N Rats and... 15.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr442.pdf

    ... Acid, NTP TR 442 group with glycine or glucuronic acid and reduction to ... Amino Acids (% of total diet) Arginine Cystine Glycine Histidine Isoleucine Leucine Lysine ...

  40. DART-06: Modified One-Generation Study of 2-Ethylhexyl p-Methoxycinnam... 5.2MB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart06_508.pdf

    ... p-methoxycinnamate glucuronide; (4) p-methoxycinnamate glycine; (5) hydroxycinnamate sulfate; (6) hydroxycinnamate glycine; (7) hydroxy methoxycinnamate; (8) hydroxy ...

  41. 15th RoC: Appendix F 174KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf

    ... N-methyl-N-nitroso-glycine see N-Nitrosamines: 15 Listings, N-Nitrososarcosine ... N,N-bis(carboxymethyl)glycine see Nitrilotriacetic Acid N,N'-bis(2-chloroethyl)-N-nitrosou...

  42. RoC Profile: Heterocyclic Amines (Selected); 15th RoC 2021 184KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/heterocyclicamines.pdf

    ... C, Wakabayashi K, Tsuda M, Sato S, Sugimura T. 1984. Formation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in a model system by heating creatinine, glycine and glucose. ...

  43. TR-340: Iodinated Glycerol (Organidin) (CASRN 5634-39-9) in F344... 9.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr340.pdf

    ... once to me- dium containing thymidine, hypoxanthine, methotrexate, and glycine for 1 day, to thymi- dine, hypoxanthine, and glycine for 1day, and to normal medium for 3-5 days. ...

  44. TR-364: Rhodamine 6G (C.I. Basic Red 1) (CASRN 989-38-8) in F344... 11.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr364.pdf

    ... once to me- dium containing thymidine, hypoxanthine, methotrexate, and glycine for 1 day, to thymi- dine, hypoxanthine, and glycine for 1day, and to normal medium for 3-5 days. ...

  45. TR592: Dietary Zinc (CASRN 5263-02-5) In Sprague Dawley Rats... 2.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr592_508.pdf

    ... triglyceride levels were seen in men taking 0.43 mg per day as zinc glycine chelate 139 . ... Ghani NA. A preliminary study of the bioavailability of iron- and zinc-glycine chelates. ...

  46. TOX-23: o-,m-, and p- Nitrotoluenes (CASRNs 88-72-2, 99-08-1... 15.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox023.pdf

    ... corresponding benzyl alcohol and to benzoic acid in the liver; the m- and p-isomers underwent conjugation with glycine to form the hippuric acid, or nitro reduction and acylation. ...

  47. TOX-41: 1,1,1-Trichloroethane (CASRN 71-55-6) 2.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox041.pdf

    ... containing thymidine, hypoxanthine, methotrexate, and glycine for 1 day; to medium containing thymidine, hypoxanthine, and glycine for 1 day; and to normal medium for 3 to 5 days. ...

  48. TR-351: para-Chloroaniline Hydrochloride (CASRN 20265-96-7) in... 12.2MB

    https://ntp.niehs.nih.gov/go/tr351

    ... once to medium containing thymidine, hypoxanthine, methotrexate, and glycine for 1 day, to thymi- dine, hypoxanthine, and glycine for 1 day, and to normal medium for 3-5 days. ...

  49. TR-371: Toluene (CASRN108-88-3) in F344/N Rats and B6C3F1Mice... 15.6MB

    https://ntp.niehs.nih.gov/go/tr371

    ... then to Phase II conjugation via mainly glycine (hip- puric acid) and, to a lesser ... to benzoic, phenylacetic, and mandelic acids, these are ex- creted as glycine conjugates. ...

  50. Draft DART-06: Modified One-Generation Study of 2-Ethylhexyl... 2.7MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/october/dart06_508.pdf

    ... glucuronide; (4) p-methoxycinnamate 3 glycine; (5) hydroxycinnamate sulfate; (6) hydroxycinnamate glycine; (7) hydroxy methoxycinnamate; (8) hydroxy 4 ...

 
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