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Search suggestions for "56-53-1".

  1. CEBS Data Related to Diethylstilbestrol (56-53-1) https://cebs.niehs.nih.gov/cebs/test_article/56-53-1
  2. Report on Carcinogens Diethylstilbestrol https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/diethylstilbestrol.pdf


232 results found for "56-53-1".

  1. RoC Profile: Diethylstilbestrol; 15th RoC 2021 141KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/diethylstilbestrol.pdf

    Diethylstilbestrol CAS No. 56-53-1 Known to be a human carcinogen First listed in the First Annual Report on Carcinogens (1980) Also known as DES, diethylstilboestrol, or ...

  2. Abstract for TER93137 65KB

    https://ntp.niehs.nih.gov/publications/abstracts/dev/ter93137

    Developmental Toxicity of Diethystilbestrol in Swiss (CD-1) Mice CASRN: 56-53-1 Chemical ... This study evaluated the potential for diethylstilbestrol to alter the skeletal morphology ...

  3. Abstract for RACB83046 61KB

    https://ntp.niehs.nih.gov/publications/abstracts/repro/racb83046

    46abs Abstract for RACB83046 Diethylstilbestrol: Fertility Assessment in CD-1 Mice When Administered in Feed CASRN: 56-53-1 Chemical Formula: C18H20O2 Molecular Weight: 268.35 ...

  4. Abstract for RACB83094 60KB

    https://ntp.niehs.nih.gov/publications/abstracts/repro/racb83094

    Abstract for RACB83094 Reproductive and Fertility Assessment of Trans-Diethylstilbestrol (DES) in CD-1 Mice When Administered in the Feed CASRN: 56-53-1 Chemical Formula: C18H20O2 ...

  5. Endocrine Disruptors Low-Dose Peer Review, October 10-12, 2000 17.3MB

    https://ntp.niehs.nih.gov/ntp/pressctr/mtgs_wkshps/2000/lowdosepeerfinalrpt.pdf

    ... The selected studies included treatments with bisphenol A, diethylstilbestrol, ethinyl ... For those studies that included DES exposure groups, those that showed an effect with ...

  6. BG1Luc ER TA Protocol Standardization Study Report (Annex C of... 2.9MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexc/c0-prot-stand.pdf

    ... C-73 10.2.6 N0006 - Diethylstilbestrol ......C-159 15.2.3 N0006 - Diethylstilbestrol ......

  7. CERHR Monograph: Soy Infant Formula 122.6MB

    https://ntp.niehs.nih.gov/ntp/ohat/genistein-soy/soyformula/soymonograph2010_508.pdf

    ... exposure to the synthetic estrogen diethylstilbestrol is also associated with fbroid ... and Newbold, R. (2005). Prenatal diethylstilbestrol (DES) exposure is associated with ...

  8. CERHR Monograph: Potential Human Reproductive and Developmental... 6.3MB

    https://ntp.niehs.nih.gov/ntp/ohat/bisphenol/bisphenol.pdf

    ...of.the.potent.estrogen. diethylstilbestrol.(63, 65). are the in vivo effects reproducible? ...studies,.potent.estrogens,. such.as.diethylstilbestrol,.ethinyl.estradiol,.17β- ...

  9. Coagulating gland - Hyperplasia - Nonneoplastic Lesion Atlas 291KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/coagulating-gland/Hyperplasia

    Feminization from prenatal exposure to estrogenic agents, including diethylstilbestrol, ... the reproductive tract of male rats induced by neonatal treatment with diethylstilbestrol. ...

  10. Uterus, Endometrium - Metaplasia, Squamous - Nonneoplastic Lesion... 295KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/uterus/Endometrium-MetaplasiaSquamous

    changes following administration of compounds with estrogenic activity, such as genistein, diethylstilbestrol, and dioxins. Vitamin A deficiency also causes squamous metaplasia. ...

  11. Coagulating Gland - Hyperplasia 760KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/male_reproductive/coagulating_gland/hyperpl/coagulating-gland-hyperplasia-pdf_508.pdf

    Feminization from prenatal exposure to estrogenic agents, including diethylstilbestrol, ... the reproductive tract of male rats induced by neonatal treatment with diethylstilbestrol. ...

  12. Listed Substances; 15th RoC 2021 76KB

    https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf

    Tars and Coal-Tar Pitches Coke-Oven Emissions Cyclophosphamide Cyclosporin A Diethylstilbestrol Dyes Metabolized to Benzidine (Benzidine Dye Class) (see Benzidine and Dyes ...

  13. XDS Submission of the LUMI-CELL ER Test Method 3.2MB

    https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/iccvamsubmission28jan05.pdf

    ... to that of 17b-estradiol 45. pg - pico grams 46. ug or mg - micro grams 47. DES - Diethylstilbestrol 48. BPA - Bisphenol A 11 Submission of XDS's LUMI-CELL ER High-Throughput ...

  14. Submission of XDS's LUMI-CELL ER High-Throughput System for Screening... 2.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexa/xds-sub.pdf

    ... to that of 17b-estradiol 45. pg - pico grams 46. ug or mg - micro grams 47. DES - Diethylstilbestrol 48. BPA - Bisphenol A 11 Submission of XDS's LUMI-CELL ER High-Throughput ...

  15. Appendix G; 15th RoC 2021 73KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf

    see 1,4-Butanediol Dimethanesulfonate 56-23-5 see Carbon Tetrachloride 56-53-1 see Diethylstilbestrol 56-55-3 (benz[a]anthracene) see Polycyclic Aromatic Hydrocarbons: 15 ...

  16. TOX-79: Genistein (CASRN 446-72-0) 2.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox079.pdf

    ... the potent estrogen diethylstilbesterol (DES) has underlined the potential consequences ... While the association between exposure to pharmacological doses of DES at critical ...

  17. Health Canada Lot Release Program for Biologic Drugs 308KB

    https://ntp.niehs.nih.gov/iccvam/methods/biologics/vaccine/canada-lotreleaseprgm.pdf

    Ligne directrice à l'intention des promoteurs: Programme d'Autorisation de Mise en Circulation des Lots de Drogues Visées à l'Annexe D (Produits Biologiques) Catalogue No. ...

  18. Bone - Fibro-osseous Lesion - Nonneoplastic Lesion Atlas 294KB

    https://ntp.niehs.nih.gov/atlas/nnl/musculoskeletal-system/bone/Fibro-osseousLesion

    ... Greenman DL, Delongchamp RR. 1986. Interactive response to diethylstilbestrol in C3H mice. ... in mice continuously fed diets containing diethylstilbestrol or 17 beta-estradiol. ...

  19. Bone - Fibro-osseous Lesion 486KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/musculoskeletal/bone/fiboss/bone-fibro-osseous-lesion-pdf_508.pdf

    ... Greenman DL, Delongchamp RR. 1986. Interactive response to diethylstilbestrol in C3H mice. ... in mice continuously fed diets containing diethylstilbestrol or 17 beta-estradiol. ...

  20. Testis - Rete Hyperplasia - Nonneoplastic Lesion Atlas 289KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/testis/ReteHyperplasia

    Bullock BC, Newbold RR, McLachlan JA. 1988. Lesions of testis and epididymis associated with prenatal diethylstilbestrol exposure. Environ Health Perspect 77:29-31. Abstract: ...

  21. Reproductive Abstracts 202KB

    https://ntp.niehs.nih.gov/publications/abstracts/repro

    ... Mice When Administered via the Diet 1984 Reproductive RACB83046 Diethylstilbestrol (EHRT) Diethylstilbestrol (CASRN: 56-53-1): Fertility Assessment in CD-1 Mice When ...

  22. ICCVAM Test Method Evaluation Report on the BG1Luc ER TA Test... 17.5MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/bg1lucer-ta-tmer-combined.pdf

    ... (1/1) POS (1/1) Dicofol 115-32-2 POS POS POS (1/1) NEG (1/1) POS (1/1) Diethylstilbestrol 56-53-1 POS POS POS (3/3) POS (3/3) POS (3/3) Estrone 53-16-7 POS POS POS (1/1) POS (1/...

  23. Uterus, Endometrium - Metplasia, Squamous 482KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/female_reproductive/uterus/enmetapsq/uterus-endometrium-metaplasia-squamous-pdf-508.pdf

    changes following administration of compounds with estrogenic activity, such as genistein, diethylstilbestrol, and dioxins. Vitamin A deficiency also causes squamous metaplasia. ...

  24. Testis, Rete Testis - Hyperplasia 597KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/male_reproductive/testis/rethyperpl/testis_rete_testis-hyperplasia_508.pdf

    http://www.ncbi.nlm.nih.gov/nlmcatalog/9002563 Bullock BC, Newbold RR, McLachlan JA. 1988. Lesions of testis and epididymis associated with prenatal diethylstilbestrol exposure. ...

  25. Presentation: Adverse Outcome Pathway for Effects of Anticoagulant... 3.2MB

    https://ntp.niehs.nih.gov/iccvam/meetings/aop-wksp-2014/presentations/rattner-508.pdf

    ... of Coagulopathy Clearance of "functional" clotting factors in humans Appearance of "des-carboxy dysfunctional" factors Clotting Factor II VII IX X Half-Life 48-120 hr 2-6 hr ...

  26. 15th RoC: Appendix F 174KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf

    ... DEHP see Di(2-ethylhexyl) Phthalate DEN see N-Nitrosamines: 15 Listings, N-Nitrosodiethylamine DES see Diethylstilbestrol DMN see N-Nitrosamines: 15 Listings, N-Nitrosodimethylamin...

  27. Study Abstracts 375KB

    https://ntp.niehs.nih.gov/publications/abstracts

    ... Mice When Administered via the Diet 1984 Reproductive RACB83046 Diethylstilbestrol (EHRT) Diethylstilbestrol (CASRN: 56-53-1): Fertility Assessment in CD-1 Mice When ...

  28. Coagulating gland - Inflammation - Nonneoplastic Lesion Atlas 292KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/coagulating-gland/Inflammation

    Arai Y, Mori T, Suzuki Y, Bern HA. 1983. Long-term effects of perinatal exposure to sex steroids and diethylstilbestrol on the reproductive system of male mammals. Int Rev Cytol ...

  29. Addendum to ICCVAM Evaluation of In Vitro Test Methods for Detecting... 2.9MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edaddendfinal.pdf

    ... 1 3 Amin es 2 1 Amino Acids 1 P 6 P P Azi des 1 P P P Carboxylic Acids 5 1 1 1 1 1 1 1 ... ### ## # #- - Amid es 1 1 Amin es 1 1 Azi des 1 P P P 6 Carboxylic Acids 5 1 1 1 1 1 1 1 ...

  30. Epididymis - Inflammation - Nonneoplastic Lesion Atlas 293KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/epididymis/Inflammation

    ... Atanassova N, McKinnell C, Fisher J, Sharpe RM. 2005. Neonatal treatment of rats with diethylstilbestrol (DES) induces stromal-epithelial abnormalities of the vas deferens and ...

  31. Coagulating Gland - Inflammation 771KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/male_reproductive/coagulating_gland/inflamm/coagulating-gland-inflammation-pdf_508.pdf

    ... References: Arai Y, Mori T, Suzuki Y, Bern HA. 1983. Long-term effects of perinatal exposure to sex steroids and diethylstilbestrol on the reproductive system of male mammals. ...

  32. RoC Profile: Safrole; 15th RoC 2021 130KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/safrole.pdf

    ... Safrole has also been used in the illicit pro- duction of the drug 3,4-methylenedioxymethamphetamine (MDMA, or ecstasy), and the U.S. Drug Enforcement Administration has des- ...

  33. Submission of the CertiChem Cell Proliferation Test Method for... 3.1MB

    https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/submdoc.pdf

    ... by examining 10 test chemicals, some with strong EA (17β-estradiol (E2), diethylstilbestrol (DES), 17α-ethinyl estradiol EE), some with moderate EA (GEN, BPA), some with weak EA ...

  34. Epididymis - Inflammation 1.2MB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/male_reproductive/epididymis/inflamm/epididymis_inflammation_508_pdf.pdf

    ... References: Atanassova N, McKinnell C, Fisher J, Sharpe RM. 2005. Neonatal treatment of rats with diethylstilbestrol (DES) induces stromal-epithelial abnormalities of the vas ...

  35. Session 3 Presentation Abstracts and Background Materials: SACATM... 224KB

    https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2020/september/session_3_abstracts_sacatm2020_508.pdf

    ... This abstract des not necessarily reflect U.S. EPA policy. Background . Variability in In Vivo Studies: Defining the Upper Limit of Performance for Predictions of Systemic Effect ...

  36. TR-235: Zearalenone (CASRN 17924-92-4) in F344/N Rats and B6C3F1Mice... 6.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr235.pdf

    ... In the immature mouse uterus, zeranol was the strongest competitor for cytoplasmic estradiol receptor sites, stronger than either zea- ralenone or diethylstilbestrol (DES) ...

  37. ICCVAM Authorization Act of 2000 73KB

    https://ntp.niehs.nih.gov/iccvam/docs/about_docs/pl106545.pdf

    ... as nonvoting ex officio members the agency heads specified in subsection (c) (or their des- ignees). (e) DUTIES.-The ICCVAM shall, consistent with the purposes described in ...

  38. Literature Search Results: Systematic Review of Long-term Neurological... 260KB

    https://ntp.niehs.nih.gov/ntp/ohat/sarin/literature_results_508.pdf

    ... A clinical experience in Japan Self Defense Force (JSDF) Central Hospital. Revue Internationale Des Services De Sante Des Forces Armees 69(4-6): 97-102. Okudera H. 2002. Clinical ...

  39. Minutes: BSC; Feb. 5, 1998 713KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1998/february/19980205bscmins_508.pdf

    ... There were four human carcinogens chosen for study: diethylstilbestrol (DES), melphalan, cyclosporin A, and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). He described the ...

  40. TR-547: Ethinyl Estradiol (multigenerational) (CASRN 57-63-6... 8.3MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr547.pdf

    ... Diethylstilbestrol is an orally bioavailable syn- thetic estrogen that has an estrogen ... receptor "-selective potency than diethylstilbestrol in some transcriptional activation ...

  41. NICEATM Validation Study Report on the MCF-7 Cell Proliferation... 1.8MB

    https://ntp.niehs.nih.gov/iccvam/methods/endocrine/mcf7/mcf7-valstudyreport-19jun12-wcv2-draft.pdf

    ... NEG (3/3) NEG (1/1) NT NEG NEG 2 Diethylstilbestrol POS (3/3) POS (3/3) POS (1/1) POS ... 2 Corticosterone NEG (3/3) NT NEG 2 Diethylstilbestrol POS (7/7) POS (1/1) POS 2 Flavone ...

  42. TR-412: 4,4'-Diamino-2,2'-Stilbenedisulfonic Acid Disodium Salt... 11.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr412.pdf

    ... disodium salt, and DNS are related structurally to the synthetic hormone diethylstilbestrol (DES) (Hammond et aL, 1987), and in some studies 4,4'-diamino-2,2'-stilbenedisulfonic ...

  43. Protocol: Evidence Map of Inflammation-Based Atherosclerosis... 643KB

    https://ntp.niehs.nih.gov/sites/default/files/2023-07/protocol_atherosclerosis_supplementaljuly2023_508.pdf

    ... OR dichlorvos[tiab] OR dieldrin[tiab] OR diesel[tiab] OR Diethylstilbestrol[mh] OR diethylstilbestrol[tiab] OR dimethyl-phthalate[tiab] OR dioxane*[tiab] OR ...

  44. Public Comment: 2-Butoxyethanol (Attachment); Seth Barna; RoC... 758KB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2013/publiccomm/barna_attachmentacc_508be.pdf

    ... P. c. F. (2010). "EGBE kidney toxicity and ethyl acetate reproductive toxicity." Archives des Maladies Professionnelles et de l'Environnement 71(4): 703. Attachment 2 Page 6 of 56 ...

  45. Appendices A-G; 15th RoC 2021 448KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf

    ... DEHP see Di(2-ethylhexyl) Phthalate DEN see N-Nitrosamines: 15 Listings, N-Nitrosodiethylamine DES see Diethylstilbestrol DMN see N-Nitrosamines: 15 Listings, N-Nitrosodimethylamin...

  46. RoC Profile: Arsenic and Inorganic Arsenic Compounds; 15th RoC... 152KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/arsenic.pdf

    ... Exports classified as arsenic metal may include arse- nic-containing e-waste, such as computers and other electronics des- tined for reclamation and recycling in other countries. ...

  47. Nomination of MAT Test for Pyrogen Detection (April 2011) 1.4MB

    https://ntp.niehs.nih.gov/iccvam/methods/pyrogen/mat-2011/iccvamnom-pyrodetecthk290311f-508.pdf

    ... Curr Pharm Des. 12 , 4163-4172 (2006 ) 8 Kern J. A. , R.J . Lamb , J.C. Reed , R.P . Daniele , and P.C . Nowell: Dexamethasone Inhibition of lnterleukin 1 Beta Production by Human ...

  48. CERHR Monograph: Amphetamines 4.1MB

    https://ntp.niehs.nih.gov/ntp/ohat/stimulants/amphetamines/amphetaminemonograph.pdf

    ...y.Shire.Pharmacueticals..d-Methamphetamine. hydrochloride.is.marketed.under.the.name.Des- oxyn£¨.by.Abbott.Laboratories..Generic.versions. of.these.two.drugs.are.also.manufactured. ...

  49. TR-539: Multigenerational Reproductive Toxicology Study of Genistein... 24.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr539.pdf

    ... to hormonally active agents such as diethylstilbestrol during development (Bern, 1992; ... and altered morphology induced by 75 ppb diethylstil- bestrol (DES) (Fritz et al., 2003). ...

  50. Mining Potential Chemical Co-exposures from Consumer Product... 3.3MB

    https://ntp.niehs.nih.gov/iccvam/meetings/commprac-2021/20210126-iccvam-cop-isaacs-508.pdf

    ... Arnot Research and Consulting Jon Arnot Johnny Westgate Institut National de l'Environnement et des Risques (INERIS) Frederic Bois Integrated Laboratory Systems Kamel Mansouri ...

 
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