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Search suggestions for "56-53-1".

  1. Report on Carcinogens Diethylstilbestrol https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/diethylstilbestrol.pdf
  2. CEBS Data Related to Diethylstilbestrol (56-53-1) https://cebs.niehs.nih.gov/cebs/test_article/56-53-1


207 results found for "56-53-1".

  1. Validation, qualification et acceptation réglementaire des nouvelles... 2.3MB

    https://ntp.niehs.nih.gov/sites/default/files/2025-05/VWG_Report_French_FR-FR_508.pdf

    réglementaire des nouvelles méthodes d'approche (NAM) Mars 2024 doi:10.22427/NICEATM-2 Validation, qualification et acceptation réglementaire des NAM Mars 2024 ii Table ...

  2. RoC Profile: Diethylstilbestrol; 15th RoC 2021 141KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/diethylstilbestrol.pdf

    Diethylstilbestrol CAS No. 56-53-1 Known to be a human carcinogen First listed in the First Annual Report on Carcinogens (1980) Also known as DES, diethylstilboestrol, or ...

  3. Abstract for TER93137 59KB

    https://ntp.niehs.nih.gov/publications/abstracts/dev/ter93137

    Developmental Toxicity of Diethystilbestrol in Swiss (CD-1) Mice CASRN: 56-53-1 Chemical ... This study evaluated the potential for diethylstilbestrol to alter the skeletal morphology ...

  4. Abstract for RACB83046 55KB

    https://ntp.niehs.nih.gov/publications/abstracts/repro/racb83046

    46abs Abstract for RACB83046 Diethylstilbestrol: Fertility Assessment in CD-1 Mice When Administered in Feed CASRN: 56-53-1 Chemical Formula: C18H20O2 Molecular Weight: 268.35 ...

  5. Abstract for RACB83094 53KB

    https://ntp.niehs.nih.gov/publications/abstracts/repro/racb83094

    Abstract for RACB83094 Reproductive and Fertility Assessment of Trans-Diethylstilbestrol (DES) in CD-1 Mice When Administered in the Feed CASRN: 56-53-1 Chemical Formula: C18H20O2 ...

  6. BG1Luc ER TA Protocol Standardization Study Report (Annex C of... 2.9MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexc/c0-prot-stand.pdf

    ... C-73 10.2.6 N0006 - Diethylstilbestrol ......C-159 15.2.3 N0006 - Diethylstilbestrol ......

  7. CERHR Monograph: Soy Infant Formula 122.6MB

    https://ntp.niehs.nih.gov/go/soy_monograph

    ... exposure to the synthetic estrogen diethylstilbestrol is also associated with fbroid ... and Newbold, R. (2005). Prenatal diethylstilbestrol (DES) exposure is associated with ...

  8. CERHR Monograph: Potential Human Reproductive and Developmental... 6.3MB

    https://ntp.niehs.nih.gov/go/bisphenol_monograph

    ...of.the.potent.estrogen. diethylstilbestrol.(63, 65). are the in vivo effects reproducible? ...studies,.potent.estrogens,. such.as.diethylstilbestrol,.ethinyl.estradiol,.17β- ...

  9. Coagulating gland - Hyperplasia - Nonneoplastic Lesion Atlas 283KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/coagulating-gland/Hyperplasia

    Feminization from prenatal exposure to estrogenic agents, including diethylstilbestrol, ... the reproductive tract of male rats induced by neonatal treatment with diethylstilbestrol. ...

  10. Uterus, Endometrium - Metaplasia, Squamous - Nonneoplastic Lesion... 289KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/uterus/Endometrium-MetaplasiaSquamous

    changes following administration of compounds with estrogenic activity, such as genistein, diethylstilbestrol, and dioxins. Vitamin A deficiency also causes squamous metaplasia. ...

  11. Coagulating Gland - Hyperplasia 760KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/male_reproductive/coagulating_gland/hyperpl/coagulating-gland-hyperplasia-pdf_508.pdf

    Feminization from prenatal exposure to estrogenic agents, including diethylstilbestrol, ... the reproductive tract of male rats induced by neonatal treatment with diethylstilbestrol. ...

  12. Listed Substances; 15th RoC 2021 76KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/listed_substances_508.pdf

    Tars and Coal-Tar Pitches Coke-Oven Emissions Cyclophosphamide Cyclosporin A Diethylstilbestrol Dyes Metabolized to Benzidine (Benzidine Dye Class) (see Benzidine and Dyes ...

  13. XDS Submission of the LUMI-CELL ER Test Method 3.2MB

    https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/iccvamsubmission28jan05.pdf

    ... to that of 17b-estradiol 45. pg - pico grams 46. ug or mg - micro grams 47. DES - Diethylstilbestrol 48. BPA - Bisphenol A 11 Submission of XDS's LUMI-CELL ER High-Throughput ...

  14. Submission of XDS's LUMI-CELL ER High-Throughput System for Screening... 2.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexa/xds-sub.pdf

    ... to that of 17b-estradiol 45. pg - pico grams 46. ug or mg - micro grams 47. DES - Diethylstilbestrol 48. BPA - Bisphenol A 11 Submission of XDS's LUMI-CELL ER High-Throughput ...

  15. Appendix G; 15th RoC 2021 69KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/appendix_g.pdf

    see 1,4-Butanediol Dimethanesulfonate 56-23-5 see Carbon Tetrachloride 56-53-1 see Diethylstilbestrol 56-55-3 (benz[a]anthracene) see Polycyclic Aromatic Hydrocarbons: 15 ...

  16. Bone - Fibro-osseous Lesion - Nonneoplastic Lesion Atlas 287KB

    https://ntp.niehs.nih.gov/atlas/nnl/musculoskeletal-system/bone/Fibro-osseousLesion

    ... Greenman DL, Delongchamp RR. 1986. Interactive response to diethylstilbestrol in C3H mice. ... in mice continuously fed diets containing diethylstilbestrol or 17 beta-estradiol. ...

  17. TOX-79: Reproductive Dose Range-Finding Toxicity Study of Genistein... 1.4MB

    https://ntp.niehs.nih.gov/go/tox079

    ... the potent estrogen diethylstilbesterol (DES) has underlined the potential consequences ... While the association between exposure to pharmacological doses of DES at critical ...

  18. Bone - Fibro-osseous Lesion 486KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/musculoskeletal/bone/fiboss/bone-fibro-osseous-lesion-pdf_508.pdf

    ... Greenman DL, Delongchamp RR. 1986. Interactive response to diethylstilbestrol in C3H mice. ... in mice continuously fed diets containing diethylstilbestrol or 17 beta-estradiol. ...

  19. Testis - Rete Hyperplasia - Nonneoplastic Lesion Atlas 282KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/testis/ReteHyperplasia

    Bullock BC, Newbold RR, McLachlan JA. 1988. Lesions of testis and epididymis associated with prenatal diethylstilbestrol exposure. Environ Health Perspect 77:29-31. Abstract: ...

  20. Uterus, Endometrium - Metplasia, Squamous 482KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/female_reproductive/uterus/enmetapsq/uterus-endometrium-metaplasia-squamous-pdf-508.pdf

    changes following administration of compounds with estrogenic activity, such as genistein, diethylstilbestrol, and dioxins. Vitamin A deficiency also causes squamous metaplasia. ...

  21. Testis, Rete Testis - Hyperplasia 597KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/male_reproductive/testis/rethyperpl/testis_rete_testis-hyperplasia_508.pdf

    http://www.ncbi.nlm.nih.gov/nlmcatalog/9002563 Bullock BC, Newbold RR, McLachlan JA. 1988. Lesions of testis and epididymis associated with prenatal diethylstilbestrol exposure. ...

  22. Reproductive Abstracts 196KB

    https://ntp.niehs.nih.gov/publications/abstracts/repro

    ... Mice When Administered via the Diet 1984 Reproductive RACB83046 Diethylstilbestrol (EHRT) Diethylstilbestrol (CASRN: 56-53-1): Fertility Assessment in CD-1 Mice When ...

  23. 15th RoC: Appendix F 165KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/appendix_f.pdf

    ... DEHP see Di(2-ethylhexyl) Phthalate DEN see N-Nitrosamines: 15 Listings, N-Nitrosodiethylamine DES see Diethylstilbestrol DMN see N-Nitrosamines: 15 Listings, N-Nitrosodimethylamin...

  24. Coagulating gland - Inflammation - Nonneoplastic Lesion Atlas 285KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/coagulating-gland/Inflammation

    Arai Y, Mori T, Suzuki Y, Bern HA. 1983. Long-term effects of perinatal exposure to sex steroids and diethylstilbestrol on the reproductive system of male mammals. Int Rev Cytol ...

  25. ICCVAM Test Method Evaluation Report on the BG1Luc ER TA Test... 17.5MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/bg1lucer-ta-tmer-combined.pdf

    ... (1/1) POS (1/1) Dicofol 115-32-2 POS POS POS (1/1) NEG (1/1) POS (1/1) Diethylstilbestrol 56-53-1 POS POS POS (3/3) POS (3/3) POS (3/3) Estrone 53-16-7 POS POS POS (1/1) POS (1/...

  26. QIVIVE and Variability Distributions in Elimination Using TKPlate 4.0MB

    https://ntp.niehs.nih.gov/sites/default/files/2025-01/2b_3_Dorne_EPAWksp2024_508.pdf

    APCRA Case Study 6 EFSA NAMS CASE STUDY ON ESSENTIAL OILS Des ign a nd conduct a s eries of NAM-bas ed experimental s tudies for a s s es s ing qua lita tive a nd qua ntita tive ...

  27. Study Abstracts 370KB

    https://ntp.niehs.nih.gov/publications/abstracts

    ... Mice When Administered via the Diet 1984 Reproductive RACB83046 Diethylstilbestrol (EHRT) Diethylstilbestrol (CASRN: 56-53-1): Fertility Assessment in CD-1 Mice When ...

  28. Epididymis - Inflammation - Nonneoplastic Lesion Atlas 286KB

    https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/epididymis/Inflammation

    ... Atanassova N, McKinnell C, Fisher J, Sharpe RM. 2005. Neonatal treatment of rats with diethylstilbestrol (DES) induces stromal-epithelial abnormalities of the vas deferens and ...

  29. Coagulating Gland - Inflammation 771KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/male_reproductive/coagulating_gland/inflamm/coagulating-gland-inflammation-pdf_508.pdf

    ... References: Arai Y, Mori T, Suzuki Y, Bern HA. 1983. Long-term effects of perinatal exposure to sex steroids and diethylstilbestrol on the reproductive system of male mammals. ...

  30. RoC Profile: Safrole; 15th RoC 2021 130KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/safrole.pdf

    ... Safrole has also been used in the illicit pro- duction of the drug 3,4-methylenedioxymethamphetamine (MDMA, or ecstasy), and the U.S. Drug Enforcement Administration has des- ...

  31. Addendum to ICCVAM Evaluation of In Vitro Test Methods for Detecting... 2.9MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edaddendfinal.pdf

    ... 1 3 Amin es 2 1 Amino Acids 1 P 6 P P Azi des 1 P P P Carboxylic Acids 5 1 1 1 1 1 1 1 ... ### ## # #- - Amid es 1 1 Amin es 1 1 Azi des 1 P P P 6 Carboxylic Acids 5 1 1 1 1 1 1 1 ...

  32. Epididymis - Inflammation 1.2MB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/male_reproductive/epididymis/inflamm/epididymis_inflammation_508_pdf.pdf

    ... References: Atanassova N, McKinnell C, Fisher J, Sharpe RM. 2005. Neonatal treatment of rats with diethylstilbestrol (DES) induces stromal-epithelial abnormalities of the vas ...

  33. 15th Report on Carcinogens 92KB

    https://ntp.niehs.nih.gov/research/assessments/cancer/roc

    ... Grade) Diepoxybutane Diesel Exhaust Particulates Di(2-ethylhexyl) Phthalate Diethylstilbestrol Diethyl Sulfate Diglycidyl Resorcinol Ether 3,3'-Dimethoxybenzidine and Dyes ...

  34. Submission of the CertiChem Cell Proliferation Test Method for... 3.1MB

    https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/submdoc.pdf

    ... by examining 10 test chemicals, some with strong EA (17β-estradiol (E2), diethylstilbestrol (DES), 17α-ethinyl estradiol EE), some with moderate EA (GEN, BPA), some with weak EA ...

  35. Validation, Qualification, and Regulatory Acceptance of New Approach... 2.3MB

    https://ntp.niehs.nih.gov/sites/default/files/2025-05/VWG_Report_Portuguese_PT-BR_508.pdf

    ... teste integradas e dados gerados a partir desses métodos para fundamentar os requisitos ... ampla de aplicações de NAM. Cada um desses conceitos-chave é apresentado de forma ...

  36. TR-235: Zearalenone (CASRN 17924-92-4) in F344/N Rats and B6C3F1Mice... 6.8MB

    https://ntp.niehs.nih.gov/go/tr235

    ... In the immature mouse uterus, zeranol was the strongest competitor for cytoplasmic estradiol receptor sites, stronger than either zea- ralenone or diethylstilbestrol (DES) ...

  37. ICCVAM Authorization Act of 2000 73KB

    https://ntp.niehs.nih.gov//sites/default/files/iccvam/docs/about_docs/pl106545.pdf

    ... as nonvoting ex officio members the agency heads specified in subsection (c) (or their des- ignees). (e) DUTIES.-The ICCVAM shall, consistent with the purposes described in ...

  38. TR-547: Multigenerational Reproductive Toxicology Study of Ethinyl... 4.7MB

    https://ntp.niehs.nih.gov/go/tr547

    ... Diethylstilbestrol is an orally bioavailable syn- thetic estrogen that has an estrogen ... receptor "-selective potency than diethylstilbestrol in some transcriptional activation ...

  39. Literature Search Results: Systematic Review of Long-term Neurological... 260KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/sarin/literature_results_508.pdf

    ... A clinical experience in Japan Self Defense Force (JSDF) Central Hospital. Revue Internationale Des Services De Sante Des Forces Armees 69(4-6): 97-102. Okudera H. 2002. Clinical ...

  40. TR-412: 4,4'-Diamino-2,2'-Stilbenedisulfonic Acid Disodium Salt... 11.2MB

    https://ntp.niehs.nih.gov/go/tr412

    ... disodium salt, and DNS are related structurally to the synthetic hormone diethylstilbestrol (DES) (Hammond et aL, 1987), and in some studies 4,4'-diamino-2,2'-stilbenedisulfonic ...

  41. NICEATM Validation Study Report on the MCF-7 Cell Proliferation... 1.8MB

    https://ntp.niehs.nih.gov/iccvam/methods/endocrine/mcf7/mcf7-valstudyreport-19jun12-wcv2-draft.pdf

    ... NEG (3/3) NEG (1/1) NT NEG NEG 2 Diethylstilbestrol POS (3/3) POS (3/3) POS (1/1) POS ... 2 Corticosterone NEG (3/3) NT NEG 2 Diethylstilbestrol POS (7/7) POS (1/1) POS 2 Flavone ...

  42. Appendices A-G; 15th RoC 2021 433KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/appendices_508.pdf

    ... DEHP see Di(2-ethylhexyl) Phthalate DEN see N-Nitrosamines: 15 Listings, N-Nitrosodiethylamine DES see Diethylstilbestrol DMN see N-Nitrosamines: 15 Listings, N-Nitrosodimethylamin...

  43. TR-539: Multigenerational Reproductive Toxicology Study of Genistein... 5.6MB

    https://ntp.niehs.nih.gov/go/tr539

    ... to hormonally active agents such as diethylstilbestrol during development (Bern, 1992; ... and altered morphology induced by 75 ppb diethylstil- bestrol (DES) (Fritz et al., 2003). ...

  44. EPA Health Effects Test Guidelines: Estrogen Receptor Transcriptional... 431KB

    https://ntp.niehs.nih.gov/iccvam/suppdocs/feddocs/epa/epa-890-1300.pdf

    ... Table 2. List of Proficiency Chemicals. Compound CAS No. Class 2 Test concentration range Note Diethylstilbestrol (DES) 56-53-1 Positive 10 -14 - 10 -8 M 17α-Ethynyl estradiol ...

  45. RoC Profile: Arsenic and Inorganic Arsenic Compounds; 15th RoC... 152KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/arsenic.pdf

    ... Exports classified as arsenic metal may include arse- nic-containing e-waste, such as computers and other electronics des- tined for reclamation and recycling in other countries. ...

  46. CERHR Monograph: Amphetamines 4.1MB

    https://ntp.niehs.nih.gov/go/amphetamine_monograph

    ...y.Shire.Pharmacueticals..d-Methamphetamine. hydrochloride.is.marketed.under.the.name.Des- oxyn£¨.by.Abbott.Laboratories..Generic.versions. of.these.two.drugs.are.also.manufactured. ...

  47. Nomination of MAT Test for Pyrogen Detection (April 2011) 1.4MB

    https://ntp.niehs.nih.gov/iccvam/methods/pyrogen/mat-2011/iccvamnom-pyrodetecthk290311f-508.pdf

    ... Curr Pharm Des. 12 , 4163-4172 (2006 ) 8 Kern J. A. , R.J . Lamb , J.C. Reed , R.P . Daniele , and P.C . Nowell: Dexamethasone Inhibition of lnterleukin 1 Beta Production by Human ...

  48. Mining Potential Chemical Co-exposures from Consumer Product... 3.3MB

    https://ntp.niehs.nih.gov/iccvam/meetings/commprac-2021/20210126-iccvam-cop-isaacs-508.pdf

    ... Arnot Research and Consulting Jon Arnot Johnny Westgate Institut National de l'Environnement et des Risques (INERIS) Frederic Bois Integrated Laboratory Systems Kamel Mansouri ...

  49. NTP-CERHR Monograph: Potential Human Reproductive and Developmental... 5.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/phthalates/bb-phthalate/bbp_monograph_final.pdf

    ... total pups/ group) in the 1 and 3 mg/L BBP groups and the DES-positive control (Table 2). ... testes to body weight ratio (8%). 6 0.0011 DES b ↓Body weight on pnd 22. ↓Absolute ...

  50. RoC Profile: Nitrosourea Chemotherapeutic Agents; 15th RoC 2021 215KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/nitrosoureachemotherapeuticagents.pdf

    ... It has also been applied to the skin to treat mycosis fungoi- des and psoriasis. Production CCNU was first synthesized in 1966 (IARC 1981). In 2009, it was pro- duced by two ...

 
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