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Search suggestions for "56-75-7".

  1. Report on Carcinogens Chloramphenicol sodium succinate https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/chloramphenicol.pdf


39 results found for "56-75-7".

  1. RoC Background Document: Chloramphenicol; Dec. 13-14, 2000 751KB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/chl_no_appendices_508.pdf

    FINAL Report on Carcinogens Background Document for Chloramphenicol December 13 - 14, 2000 ... 2000 RoC Background Document for Chloramphenicol Criteria for Listing Agents, ...

  2. RoC Profile: Chloramphenicol; 15th RoC 2021 144KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/chloramphenicol.pdf

    Chloramphenicol CAS No. 56-75-7 Reasonably anticipated to be a human carcinogen First listed in the Tenth Report on Carcinogens (2002) HO CH 2 CH CH C H N O 2 N CH O Cl Cl OH ...

  3. Minutes: BSC RoC; Dec. 13-15, 2000 205KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/draftbackgrounddocs/minutes20001213.pdf

    Chloramphenicol......Chloramphenicol -- Dr. Haseman presented the nomination and said that chloramphenicol was ...

  4. 15th RoC: Appendix B 103KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_b.pdf

    Substance Name CAS Number Last Listing Reason for Delisting Chloramphenicol 56-75-7 known First RoC (1980) Human data considered inadequate Aramite 140-57-8 reasonably anticipated ...

  5. Validation of In Vitro Cytotoxicity Test Methods: Test Chemicals 188KB

    https://ntp.niehs.nih.gov/iccvam/methods/acutetox/invitrocyto/ivcytodocs/valstdchm.pdf

    289116-100ml > 99.5 Chloral hydrate 302-17-0 165.40 SIGMA C8383 100.1 Chloramphenicol 56-75-7 323.14 FLUKA 23275 > 99 Citric Acid 77-92-9 192.10 SIGMA C0759 98 Colchicine ...

  6. Appendix G; 15th RoC 2021 73KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf

    56-55-3 (benz[a]anthracene) see Polycyclic Aromatic Hydrocarbons: 15 Listings 56-75-7 see Chloramphenicol 57-14-7 see 1,1-Dimethylhydrazine 57-41-0 (phenytoin) see Phenytoin and ...

  7. ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential... 10.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edfinalrpt0503/edfinrpt.pdf

    ... Service Registry Number CAT Chloramphenicol acetyl transferase (protein) cDNA ... The reporter genes used in these test methods included: . luciferase and chloramphenicol ...

  8. Appendices A-G; 15th RoC 2021 448KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf

    ... Substance Name CAS Number Last Listing Reason for Delisting Chloramphenicol 56-75-7 known First RoC (1980) Human data considered inadequate Aramite 140-57-8 reasonably anticipated ...

  9. Listed Substances; 15th RoC 2021 76KB

    https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf

    ... Hydroxyanisole Captafol Carbon Tetrachloride Ceramic Fibers (Respirable Size) Chloramphenicol Chlorendic Acid Report on Carcinogens, Fifteenth Edition National Toxicology ...

  10. Completed RoC Evaluations 119KB

    https://ntp.niehs.nih.gov/whatwestudy/assessments/cancer/completed/roc

    ... Ceramic Fibers (Respirable Size) Reasonably anticipated to be a human carcinogen Request Archived Materials Chloramphenicol Delisted Background Document Appendix Request Archived ...

  11. 15th RoC: Appendix F 174KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf

    ...phenyl)ethyl]acetamide see Chloramphenicol [R-(R*,R*)]-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4- nitrophenyl)ethyl]acetamide see Chloramphenicol 2,4-dichloro-1-(4-nitrophen...

  12. RoC Profile: Azathioprine; 15th RoC 2021 123KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/azathioprine.pdf

    .../pims/pharm/azathiop.htm. Jeebhay M, Mbuli S, Uebel R. 1993. Assessment of exposure to chloramphenicol and azathioprine among workers in a South African pharmaceutical plant. ...

  13. Expert Panel Evaluation of the Validation Status of In Vitro... 1.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/expertpanfinalrpt/panelrpt1102.pdf

    ... The luciferase and chloramphenicol acetyltransferase reporter genes were used in the ... The luciferase and chloramphenicol acetyltransferase reporter genes were used in the ...

  14. ICCVAM Background Review Document (Vol 1): In Vitro Cytotoxicity... 16.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol1_nov2006.pdf

    ... Chemical Class 6 Molecular Structure Chloramphenicol 3393 MEIC, RC, NTP Pharmaceutical ... chloride 7447-40-7 346 50 2602 0.085 Chloramphenicol 56-75-7 91 45 3393 0.441 LD 50 >5000 ...

  15. Presentation: Fundamentals of QSAR Modeling: Basic Concepts and... 7.7MB

    https://ntp.niehs.nih.gov/iccvam/meetings/commprac-2016/tropsha-508.pdf

    ... Bendazac Toxic 0.790 Phenytoin Non-toxic 0.813 Flutamide Toxic 0.783 Pemoline Non-toxic 0.766 Chloramphenicol Toxic 0.776 Phenylbutazone Non-toxic 0.737 Disulfiram Toxic 0.770 ...

  16. ICCVAM Background Review Document (Vol 2): In Vitro Cytotoxicity... 61.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol2_nov2006.pdf

    ... 11.8-7000 Chloral hydrate 302-17-0 100.1 Sigma 8.4 4.7-1000 7.6 4.7-1000 Chloramphenicol 56-75-7 > 99 Fluka 8.3 4.7-2500 7.8 9.15-2500 Citric acid 77-92-9 98 Sigma 2.9 ...

  17. TR-338: Erythromycin Stearate (CASRN 643-22-1) in F344/N Rats... 10.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr338.pdf

    ... Eryth- romycin competes with chloramphenicol for the same binding site. Binding is ... Tetracyclines, chloramphenicol, erythromycin, and miscellaneous antibacterial agents. ...

  18. TR-364: Rhodamine 6G (C.I. Basic Red 1) (CASRN 989-38-8) in F344... 11.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr364.pdf

    ... Ziegler and Davidson (1981) used chloramphenicol-resistant Chinese hamster fibroblast and mouse 3T3-4E cell lines and alternate pretreatment with rhodamine 6G to demonstrate ...

  19. TR-508: Riddelliine (CASRN 23246-96-0) in F344/N Rats and B6C3F1Mice... 9.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr508.pdf

    ... Pretreatment of the animal with phenobarbital increases the rate of metabolic conversion, while chloramphenicol or SKF 525A reduces it (Allen et al., 1972; White et al., 1983). The ...

  20. National Toxicology Program, Board of Scientific Counselors 106KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2001/may/2001052501bscsummmins_508.pdf

    ... recommended for listing as reasonably anticipated to be a human carcinogen; (2) Chloramphenicol was recommended for listing as reasonably anticipated to be a human carcinogen; ...

  21. Report: International Workshop on In Vitro Methods for Assessing... 25.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf

    ... 90 Iproniazid 54-92-2 141.61 0.79 365.7 2.04 681.2 3.8 179.25 2.04 91 45 Chloramphenicol 56-75-7 255.29 0.79 3393.1 10.5 2640.1 8.17 323.15 10.5 245 Resorcinol 108-46-3 88.10 ...

  22. RoC Background Document: Solar Radiation & Exposure to Sunlamps... 3.7MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/solar_rad_sunlamps_2apps_508.pdf

    ... UVR. The reporter gene was the enzyme chloramphenicol acetyltransferase (CAT) contained within the plasmid; repair of damaged genes was dependent on host cell DNA repair capacity. ...

  23. Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf

    ... 90 Iproniazid 0.79 2.04 365.7 91 45 Chloramphenicol 0.79 10.5 3393.1 245 Resorcinol 0.8 ... Acetic acid 24.3 55.1 3309.3 91 45 Chloramphenicol 0.79 10.5 3393.1 201 13-cis-Retinoic ...

  24. Minutes: BSC; July 14, 1987 1.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1987/december/19871214bsc_minutes_508be.pdf

    ... sequences of murine @A crystallin, murine @2(I) collagen or of avian sarcoma (lirus genes linked t o the bacterial chloramphenicol acetyl transferase expresrlon ~n transgenic mice. ...

  25. Minutes: BSC; May 24, 2000 495KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2000/may/2000052400bscsummmins_508.pdf

    ... The tentative list of remaining nominations for the 10 th Report includes chloramphenicol; estrogens, steroidal; human papillomaviruses (HPVs); lead and lead compounds; ...

  26. Background Review Document: In Vitro Test Methods for Assessing... 2.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/epis_brd0801.pdf

    ... penicillin, chloramphenicol and amphotericin B to 1 litre of luke-warm deionised water. ... 800µgml -1 penicillin; 10µgml -1 chloramphenicol; and 10µgml -1 amphotericin B. ...

  27. 21 CFR 610: FDA General Biological Products Standards 404KB

    https://ntp.niehs.nih.gov/iccvam/methods/biologics/vaccine/2008-21cfrpart610.pdf

    ... Fibrinolysin and Desoxyribonuclease Com- bined (Bovine). Fibrinolysin and Desoxyribonuclease Com- bined (Bovine) with Chloramphenicol. Hepatitis B Surface Antigen: 1. Unlyophilized ...

  28. NTP Monograph: Systematic Review of Occupational Exposure to... 6.2MB

    https://ntp.niehs.nih.gov/ntp/ohat/oeccaaho/mgraph/occchemo_final20190300_508.pdf

    ... R. 1993. Assessment of exposure to chloramphenicol and azathioprine among workers in a ... R. 1993. Assessment of exposure to chloramphenicol and azathioprine among workers in a ...

  29. ICCVAM Evaluation of In Vitro Test Methods for Assessing Dermal... 3.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/cwgfinal02/cwgfinal.pdf

    ... penicillin, chloramphenicol and amphotericin B to 1 litre of luke-warm deionised water. ... 800µgml -1 penicillin; 10µgml -1 chloramphenicol; and 10µgml -1 amphotericin B. ...

  30. OECD Guidance Document 129: Using Cytotoxicity Tests to Estimate... 1.4MB

    https://ntp.niehs.nih.gov/iccvam/suppdocs/feddocs/oecd/oecd-gd129.pdf

    ... hydrocarbon Chloral hydrate 302-17-0 183 133 638 Organic compound; Alcohol Chloramphenicol 56-75-7 128 348 3491 Organic compound; Alcohol; Cyclic hydrocarbon; Nitro compound ...

  31. ICCVAM Test Method Evaluation Report: In Vitro Cytotoxicity Test... 14.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/at-tmer-complete.pdf

    ... 518.0 3.426 Potassium chloride 7447-40-7 2602 34.90 3555 47.68 2237 30.01 Chloramphenicol 56-75-7 3393 10.50 130.2 0.4029 345.0 1.068 Lactic acid 50-21-5 3730 41.41 3044 33.79 ...

  32. TR-344: Tetracycline Hydrochloride (CASRN 64-75-5) in F344/N... 10.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr344.pdf

    ... doses of aureomycin, terramycin, and chloramphenicol on livers of mice and dogs. Arch. ... agents, Tetracyclines, chloramphenicol, erythromycin and miscellaneous antibiotic agents. ...

  33. TR-327: Xylenes (Mixed) (60%m-Xylene, 14%p-Xylene, 9%o-Xylene... 8.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr327.pdf

    ... Exp. Ther. 223:736-742. 98. Speck, B.;Moeschlin, S. (1968) Effect of toluene, xylene, chloramphenicol, and thiouracil on bone marrow. Experimental autoradio- graphic study with ...

  34. Performance Standards for In Vitro Test Methods for Skin Corrosion 6.3MB

    https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/ps/ps044510.pdf

    ... Then, the animals are washed by careful wiping, while submerging the clipped area in antibiotic solution (containing, for example, streptomycin, penicillin, chloramphenicol, and ...

  35. RoC Background Document: Ultraviolet (UV) Radiation, Broad Spectrum... 3.0MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/uv_no_appendices_508.pdf

    ... to repair damaged DNA. Plasmids containing UVR-irradiated (0, 350, or 700 J/m 2 ) chloramphenicol acetyl transferase (CAT) reporter genes were transfected into lymphocytes, and the ...

  36. TOX-35: Chemical Mixture of 25 Groundwater Contaminants 11.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox35.pdf

    ... colony-forming cells (CFUs) with respect to their sensitivity of chloramphenicol . Exp . ... with respect to their sensitivity to chloramphenicol . Exp Hernatol 1980 ; 8 :236. 41 . ...

  37. Background Document for Selected Heterocyclic Amines: PhIP, MeIQ... 3.3MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/hcaspub_508.pdf

    ... Rescued phages are transfected into E. coli and converted into plasmid pYG142 carrying a chloramphenicol resistance gene, the gpt gene of E. coli and a chi site along with the red ...

  38. CERHR Monograph: Soy Infant Formula 122.6MB

    https://ntp.niehs.nih.gov/ntp/ohat/genistein-soy/soyformula/soymonograph2010_508.pdf

    ... Human ERα-LacZ reporter-transfected yeast i 0.02 - 0.044 0.00045 hER-Chloramphenicol acetyltransferase reporter-transfected Le42 0.04 0.003 TATA-Luciferase-reporter transfected ...

  39. Peer Review Evaluation Report: Oral Up-and-down Procedure (NIH... 2.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/udpproc/udpfin01/vol_2.pdf

    ... Chloramphenicol Higher plasma levels in females. Chlordiazepoxide Lower clearance in females as compared with males. Diazepam Lower clearance in females as compared with males. ...

 
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