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Search suggestions for "56-81-5".

  1. CEBS Data Related to Glycerol (56-81-5) https://cebs.niehs.nih.gov/cebs/test_article/56-81-5


154 results found for "56-81-5".

  1. TR-340: Iodinated Glycerol (Organidin) (CASRN 5634-39-9) in F344... 9.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr340.pdf

    TOXICOLOGY AND CARCINOGENESIS STUDIES OF IODINATED GLYCEROL (ORGANIDIN®) (CAS NO. ... TOXICOLOGY AND CARCINOGENESIS STUDIES OF IODINATED GLYCEROL (ORGANIDIN*) (CAS NO. ...

  2. Abstract for TR-340 68KB

    https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr340

    Toxicology and Carcinogenesis Studies of Iodinated Glycerol (Organidin) in F344/N Rats and ... Synonyms/Common Names: Iodopropylidene glycerol Report Date: March 1990 Full Report PDF ...

  3. Target Organs and Levels of Evidence for TR-340 59KB

    https://ntp.niehs.nih.gov/data/tr/300s/tr340levels

    Toxicology and Carcinogenesis Studies of Iodinated Glycerol (Organidin) (CASRN 5634-39-9) ... Levels Study Laboratory Iodinated glycerol 5634-39-9 10/04/1988 Gavage FR&FM: 0, ...

  4. Abstract for GMM-13 67KB

    https://ntp.niehs.nih.gov/publications/reports/gmm/gmm13

    intermediate in the pharmaceutical industry, as a stabilizer in the manufacture of vinyl polymers, and as an intermediate in the synthesis of glycerol, glycidyl ethers, and amines. ...

  5. Abstract for TR-73 63KB

    https://ntp.niehs.nih.gov/publications/reports/tr/000s/tr073

    Important "first generation" derivatives of allyl chloride include glycerol, epichlorohydrin, and allyl alcohol. Other derivatives include medicinals, such as barbiturates, ...

  6. Nomination Background: 1,3-Dichloro-2-propanol (CASRN: 96-23... 1.5MB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/dichloropropanol_508.pdf

    ... Identification 1,3-DCP (CASRN 96-23-1) is also called (glycerol) α,γ-dichlorohydrin. ... Hydrolysis of dichlorohydrins has been used in the production of synthetic glycerol ...

  7. Presentation: Opportunities and Strategies to Further Reduce... 1.7MB

    https://ntp.niehs.nih.gov/iccvam/meetings/leptovaccwksp-2012/present/walker-508.pdf

    Challenge in 10 hamsters Preliminary Study Example Infected Hamster Liver (i.e. L. canicola) 1% BSA diluent P-80 semi-solid diluent 2.5% glycerol 5% glycerol 7.5% glycerol 2.5% ...

  8. Abstract for TR-384 70KB

    https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr384

    CASRN: 96-18-4 Chemical Formula: C3H5Cl3 Molecular Weight: 147.44 Synonyms/Common Names: Allyl trichloride; glycerol trichlorohydrin; glyceryl trichlorohydrin; trichlorohydrin ...

  9. TR-426: Corn Oil, Safflower Oil, and Tricaprylin (CASRNs. 8001... 18.8MB

    https://ntp.niehs.nih.gov/go/tr426

    ... l,Z,f-trioctanoyl glycerol; Glycerol trioctanoate The types and levels o f fats in the diet are known to affect the incidence o f certain neoplasms in humans and rodents. ...

  10. RoC Profile: Phenazopyridine Hydrochloride; 15th RoC 2021 120KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/phenazopyridinehydrochloride.pdf

    It is slightly soluble in cold wa- ter, ethanol, and lanolin; soluble in boiling water, acetic acid, glycerol, ethylene glycol, and propylene glycol; and insoluble in acetone, ben- ...

  11. TR-374: Glycidol (CASRN 556-52-5) In F344/N Rats and B6C3F1Mice... 11.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr374.pdf

    ... a t neutral pH and 37"C, glycidol slowly hydrolyzes to glycerol; in 0.1 M hydrochloric acid, the hydrolysis to glycerol (97.2%) and a-chlorohydrin (3-chloro- 1,2-propanediol) ...

  12. Presentation: Mechanisms of Acute Toxicity 2.4MB

    https://ntp.niehs.nih.gov/iccvam/meetings/at-wksp-2015/session4/1-wilson-508.pdf

    ... Fatty acyl CoA (odd-number carbons) Fructose Fructose 1P Glyceraldehyde Dihydroxyacetone-P Glycerol-P Triacylglycerol Fatty acyl CoA Malonyl CoA Glycerol Fatty acids Glucose CO 2 ...

  13. Presentation: Analyses of Pertussis Toxin Enzymatic and Binding... 1.1MB

    https://ntp.niehs.nih.gov/iccvam/meetings/histwksp-2012/present/yuen-508.pdf

    assay Discussion 1. BRP in 50% Glycerol may not be stable under the present ... Discussion This study: . PTx BRP was not stable under the 50% glycerol storage/dilution ...

  14. Minutes: BSC TRRS; Oct. 3, 1988 964KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1988/oct/88oct3-4trrsmins_508.pdf

    Hydroquinone 123-31-9 Gavage ~odinated Glycerol 5634-39-9 Gavage Gavage Pentaerythritol ... Iodinated Glycerol. Dr. J.E. French, NIEHS, NTP Chemical Manager, introduced t h e ...

  15. Validation of In Vitro Cytotoxicity Test Methods: Test Chemicals 188KB

    https://ntp.niehs.nih.gov/iccvam/methods/acutetox/invitrocyto/ivcytodocs/valstdchm.pdf

    346.38 ACROS 41091-0000 99 Glutethimide 77-21-4 217.30 SIGMA-ALDRICH G-102 > 99 Glycerol 56-81-5 92.09 SIGMA G5516 99.9 Haloperidol 52-86-8 375.90 SIGMA H1512 99 Hexachlorophene ...

  16. RoC Profile: Glycidol; 15th RoC 2021 127KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/glycidol.pdf

    ... oils and as an intermediate in the synthesis of glycerol, glycidyl ethers, and amines. ... Heating causes the dehydration of glycol configurations in glycerol and sugars to form ...

  17. GMM-13: Genetically Modified Model Report on Glycidol (Gavage... 905KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm13_508.pdf

    ... and as an intermediate in the synthesis of glycerol, glycidyl ethers, and amines. ... and as an intermediate in the synthesis of glycerol, glycidyl ethers, and amines. ...

  18. Salivary Gland, Duct - Metaplasia, Squamous - Nonneoplastic Lesion... 292KB

    https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/salivary-gland/Duct-MetaplasiaSquamous

    National Toxicology Program. 1990. NTP TR-340. Toxicology and Carcinogenesis Studies of Iodinated Glycerol (CAS No. 5634-39-9) in F344/N Rats and B6C3F1 Mice (Gavage Studies). NTP, ...

  19. RoC Profile: Phenacetin and Analgesic Mixtures Containing Phenacetin... 129KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/phenacetinandanalgesicmixtures.pdf

    ... Phenacetin occurs at room temperature as white, odorless mono- clinic prisms. It is soluble in water (more so in hot than cold water), alcohol, glycerol, and acetone and is ...

  20. Cover Letter for Nomination of IVSA to ICCVAM (2012) 531KB

    https://ntp.niehs.nih.gov/iccvam/methods/immunotox/ivsa/ivsa-iccvamsubmissionletter-092712-508.pdf

    ... + 9.0% 03/08/12 EtOH 0.30% 4.78 + 8.2% 03/08/12 6 Eugenol EU 97-53-0 Aldrich EtOH 1% 4.56 + 9.5% 03/08/12 EtOH C 10 H 12 O 2 164.2 liquid Weak 7 Glycerol GLC 56-81-5 Sigma-Aldrich. ...

  21. Salivary Gland, Duct - Metaplasia, Squamous 610KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/alimentary/salivary_gland/dsmetap/salivary-gland-duct-metaplasia-squamous_508.pdf

    ... Mosby, St Louis, MO, 3-62. National Toxicology Program. 1990. NTP TR-340. Toxicology and Carcinogenesis Studies of Iodinated Glycerol (CAS No. 5634-39-9) in F344/N Rats and B6C3F1 ...

  22. ICCVAM Test Method Evaluation Report: LLNA BrdU-ELISA 35.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-elisa/tmer.pdf

    ... agent Carboxylic Acids NC (1.0) NC (1.3) Glycerol Cosmetics; Food additive; Intermediate ... AOO 0.88 1.50 HPMA (1,1) AOO 1.13 1.30 Glycerol (1,1) Water/DMF 1.29 1.10 Dimethyl ...

  23. RoC Profile: Urethane; 15th RoC 2021 141KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/urethane.pdf

    ... It is soluble in water, benzene, alcohol, ether, chloroform, glycerol, and olive oil. Urethane is stable under normal temperatures and pressures (Akron 2009, HSDB 2009). Physical ...

  24. TOWARD VALIDATION OF A HUMAN IN... 1.1MB

    https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-15444/stemina/egnashposter-2014-wc.pdf

    ... NON 168 Fipronil Environmental TER 14 Diquat dibromide Environmental TER 0.1 Glycerol Environmental NON 300 Endosulfan Environmental TER 22 Hexazinone Environmental NON ...

  25. TR-384: 1,2,3-Trichloropropane (CASRN 96-18-4)in F344 Rats and... 5.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr384.pdf

    ... 147.44 Synonyms: Allyl trichloride, glycerol trichlorohydrin, glyceryl ... 147.44 Synonyms: Allyl trichloride, glycerol trichlorohydrin, glyceryl ...

  26. Advancing Flexibility for Defined Approach Guidelines: Developing... 1.2MB

    https://ntp.niehs.nih.gov/sites/default/files/2024-03/SOT2024-Sullivan-poster.pdf

    ... EGDMA 97-90-5 Y N/A 1B 1 1B Ethylene diamine (free base) 107-15-3 N N/A 1B 1 1B Glycerol 56-81-5 N N/A NC NC NC 4-Hydroxybenzoic acid 99-96-7 N N/A NC NC NC Isopropanol 67-63-0 N ...

  27. RoC Background Document: 1,2,3-Trichloropropane; Nov. 18-19,... 2.6MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/trichloropropane_508.pdf

    ... (8CI, 9CI) Allyl trichloride Glycerol trichlorohydrin Glyceryl trichlorohydrin ...dichloro-2-propanol), glycerol (glycerin) (ATSDR, 1992), and epichlorohydrin (IFIS, 1985). ...

  28. TR-528: 2,2-bis(Bromomethyl)-1,3-Propanediol, Nitromethane, and... 5.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr528.pdf

    ... 147.44 Synonyms: Allyl trichloride, glycerol trichlorohydrin, glyceryl ... 147.44 Synonyms: Allyl trichloride, glycerol trichlorohydrin, glyceryl ...

  29. Presentation: The Murine Local Lymph Node Assay: BrdU-ELISA 889KB

    https://ntp.niehs.nih.gov/iccvam/meetings/implement-2011/acd-present/6-strickland.pdf

    ... Diethyl phthalate Dimethyl isophthalate Glycerol Hexane 2-Hydroxypropyl methacrylate Isopropanol Lactic acid Methyl salicylate Propylene glycol Salicylic acid Sulfanilamide ...

  30. RoC Profile: 1,2,3-Trichloropropane; 15th RoC 2021 142KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/trichloropropane.pdf

    ... of the production of other compounds, such as epichlorohydrin, dichloropropene, propylene oxide, propylene chlo- rohydrin, dichlorohydrin, and glycerol (ATSDR 1992, IPCS 2003). ...

  31. RoC Profile: Lead and Lead Compounds; 15th RoC 2021 190KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/lead.pdf

    ... Lead acetate exists as colorless or white crystals, granules, or powders that are soluble in glycerol and slightly soluble in ethanol. Lead acetate trihydrate occurs as white ...

  32. Validation of the Electrophilic Allergen Screening Assay (EASA... 1.3MB

    https://ntp.niehs.nih.gov/iccvam/meetings/sot23/sot2023-gordon-poster.pdf

    ... Salicylic acid Neg/Inc 3 /Inc Neg/Neg/Neg Neg/Inc/Inc Neg/Inc/Inc Neg Pos-Neg/Neg Benzyl alcohol Pos/Neg/Pos Pos/Neg/Pos Neg/Neg/Neg Neg/Neg/Neg Neg Pos-Neg/Neg Glycerol Neg/Neg/...

  33. Background Document: 2,3-Dibromo-1-propanol; BSC; May 24, 2000 824KB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/dbp_no_appendices_508.pdf

    ... DBP (C 3 H 6 Br 2 O, mol wt 217.89, CASRN 96-13-9) also is known by the following names: glycerol 1,2-dibromohydrin beta-dibromohydrin dibromopropanol allyl alcohol dibromide. ...

  34. RoC Profile: Epichlorohydrin; 15th RoC 2021 158KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/epichlorohydrin.pdf

    ... manu- facturing epichlorohydrin, epoxy resins, and glycerol suggested that chemical operators at these plants had the greatest potential for ex- posure to epichlorohydrin. ...

  35. Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf

    ... Dimethyl 114 38.3 2800.1 73.11 68-12-2 D8654 >99.8% Irritant, teratogen. formamide Glycerol 624 137 12,691.1 92.11 56-81-5 G8773 >99% Irritating to eyes, skin. 11 Using In Vitro ...

  36. Comparison of devTOX quickPredict Assay With Other Methods 1.0MB

    https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-15444/stemina/comparisonspreadsheet-508.pdf

    ... NON (2) NON NON Genistein N/A N/A N/A n.d. DT n.d. DT (6) n.d. DT (14) DT (Strong, 11) DT (17) DT DT Glycerol N/A N/A N/A n.d. NON n.d. NON (6) NON (6) DT (14) n.d. NON NON NON ...

  37. RoC Background Document: Azacitidine; Nov. 18-19, 1996 3.5MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/azacitidine1_508.pdf

    ... D-Ribose is soluble in water and slightly soluble in alcohol. Urea is soluble in water, alcohol, methanol, glycerol, and concentrated HCl. It is insoluble in chloroform and ether ...

  38. TR-073: Allyl Chloride (CASRN 107-05-1) 3.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr073.pdf

    ... Impor- tant "first generation" derivatives of allyl chloride include glycerol, epichlorohydrin, and allyl alcohol (Pilorz, 1964). Other derivatives include medicinals, such as ...

  39. TOX-48: Allyl Acetate (CASRN 591-87-7), Allyl Alcohol (CASRN... 18.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox048.pdf

    ... Allyl alcohol is an important industrial chemical. The direct oxidation of allyl alcohol to glycerol by peroxide is the most widely used method of glycerol production, and this ...

  40. Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf

    ... Benzoic acid and glycerol were tested using a non-standard LLNA protocol and, in agreement ... aid (solvent)// manufacture of acetone, glycerol, isopropyl acetate - - Basketter et al. ...

  41. Background Review Document: Frog Embryo Teratogenesis Assay ... 2.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/fetax2000/brd/fetax-brd-all.pdf

    ... diethylene glycol, ethylene glycol, glycerol, phthalic acid, sodium arsenite, sodium ... teratogens in laboratory mammals, two (glycerol, phthalic acid) were classified as ...

  42. Comparison of the Stemina devTOX quickPredict system with other... 2.1MB

    https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2018-09961/palmer-stemina-spreadsheet.pdf

    ... Genistein DT n.d. n.d. DT (6) n.d. DT (14) DT (11) DT (17) 0.76 DT DT N/A N/A N/A Threshold Rodent Glycerol NON n.d. n.d. NON (6) NON (6) DT (14) n.d. NON 0.27 NON NON N/A N/A N/A ...

  43. TR-351: para-Chloroaniline Hydrochloride (CASRN 20265-96-7) in... 12.2MB

    https://ntp.niehs.nih.gov/go/tr351

    ... Gavage Vehicle Controls (b) Iodinated glycerol 0/50 0/50 0/49 0/50 0/49 Malonaldehyde, ... Associates, and the iodinated glycerol study was conducted at EG&G Mason ...

  44. ICCVAM Test Method Evaluation Report: In Vitro Test Methods for... 42.0MB

    https://ntp.niehs.nih.gov/iccvam/docs/ocutox_docs/invitro-2010/tmer-vol1.pdf

    ... Carbohydrate Food additive DL-Glutamic acid 19285-83-7 Amino acid Not classified Glycerol 56-81-5 Alcohol Solvent; Plasticizer; Lubricant; Emollient; Drug vehicle ...

  45. TOX-54: 1,4-Butanediol (CASRN 110-63-4) 577KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox054.pdf

    ... diol lipids, in which fatty acids are esterified to dihydric alcohols (diols) such as 1,2-propanediol, 1,3-propanediol, 1,3-butanediol, and 1,4-butanediol, instead of glycerol. ...

  46. ICCVAM Background Review Document (Vol 1): In Vitro Cytotoxicity... 16.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol1_nov2006.pdf

    ... among water-soluble chemicals, glycerol had the highest reported IC 50 value (57 mg/mL). ... 4.9 Organic compound; Carboxylic acid Glycerol 12691 RC, GD, NTP, HPV Solvent 92.09 ...

  47. TR-242: Diallyl Phthalate (CASRN 131-17-9) in B6C3F1Mice (Gavage... 4.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr242.pdf

    ... These epoxides were subsequently hydrolyzed to diols (glycerol, glyceraldehyde) or ... CH20H CHO I I CHOH CHOH I I CH2OH CH2OH Glycerol Glyceraldehyde - + HYPOTHETICAL ME TAB0 ...

  48. TR-474: Polyvinyl Alcohol (CASRN9002-89-5) in Female B6C3F1Mice... 3.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr474.pdf

    ... States use their product annually (VCF; Apothecus, Inc., Great Neck, NY); the product is composed of a spermicide, glycerol, and 67% polyvinyl alcohol (molecular weight 25,000). ...

  49. ICCVAM Background Review Document (Vol 2): In Vitro Cytotoxicity... 61.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol2_nov2006.pdf

    ... Assay (µg/mL) pH in NHK Medium b Concentrations Tested in NHK Assay (µg/mL) Glycerol 56-81-5 99.9 Sigma 8.2 4586-100000 7.8 47-101960 Haloperidol 52-86-8 99 Sigma 8.3 0.1-25 ...

  50. TR-284: Diallylphthalate (CASRN 131-17-9) in F344/N Rats (Gavage... 8.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr284.pdf

    ... I OH Clycidaldehyde 0 II I OH HCCItCH20H Glycerol Glyceraldehyde FIQURE 1. METABOLISM OF ... These epoxides were subsequently hydrolyzed to glycerol and glyceraldehyde or conjugated ...

 
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