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Appendices for NTP Monograph on Developmental Effects and Pregnancy... 11.1MB
https://ntp.niehs.nih.gov/ntp/ohat/cancer_chemo_preg/cancerchemo_appendfinal_508.pdf
... NA NA NA Vinblastine 3 NA D Vincristine 3 NA D Vindesine NA NA NA Vinorelbine ... vinblastine OR vincasar OR vincrex OR vincristine OR vindesine OR vinorelbine OR VM26 OR ...
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NTP Monograph: Developmental Effects and Pregnancy Outcomes Associated... 23.8MB
https://ntp.niehs.nih.gov/ntp/ohat/cancer_chemo_preg/chemopregnancy_monofinal_508.pdf
......... 159 5.33 Vincristine ......Table 77: Pharmacology of vincristine in adult humans ......
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RoC Profile: Azacitidine; 15th RoC 2021 129KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/azacitidine.pdf
... Azacitidine is also used in clinical trials in combina- tion with other antineoplastic agents, such as vincristine, prednisone, vinblastine, cytarabine, or amsacrine (IARC 1990). ...
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Public Comment: Uranium (Attachment); Donald Weir; RoC; Jan.... 127KB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2012/publiccomm/weirattachment.pdf
... FISH), the research team found that DU was an aneugenic agent (leading to overall loss of chromosomes), like Vincristine sulphate, an established aneugenic agent used as a control. ...
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RoC Background Document: Azacitidine; Nov. 18-19, 1996 3.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/azacitidine1_508.pdf
... It is used 4 NTP Report on Carcinogens 1996 Background Document for Azacitidine alone or in combination with vincristine, vinblastine, prednisone, cytarabine, or amsacrine, at a ...
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RoC Profile: Nitrosourea Chemotherapeutic Agents; 15th RoC 2021 215KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/nitrosoureachemotherapeuticagents.pdf
... CCNU is used alone or in combination with other antineo- plastic agents, including procarbazine and vincristine, etoposide and prednimustine, and other combinations (IARC 1981, ...
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OHAT Evaluation: Protocol for a Systematic Review to Evaluate... 1018KB
https://ntp.niehs.nih.gov/ntp/ohat/aheaoecca/protocol201510_508.pdf
... OR vincasar[tiab] OR vincrex[tiab] OR vincristine[tiab] OR vindesine[tiab] OR ... vinblastine OR vincasar OR vincrex OR vincristine OR vindesine OR vinorelbine OR vm26 OR ...
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Minutes: MPRP; Oct. 1-2, 2012 559KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2012/october/minutes20121002_508.pdf
... Microtubule Function Inhibitors: Vincristine Dr. Smith was first reviewer. She questioned ... lip and jaw induced in fetal rats by vincristine. 1936. Arch Anat Histol Embryol ...
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OHAT Evaluation: Protocol for a Systematic Review to Evaluate... 1.1MB
https://ntp.niehs.nih.gov/ntp/ohat/aheaoecca/protocol201812_508.pdf
... OR vincasar[tiab] OR vincrex[tiab] OR vincristine[tiab] OR vindesine[tiab] OR ... vinblastine OR vincasar OR vincrex OR vincristine OR vindesine OR vinorelbine OR vm26 OR ...
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NTP Monograph: Systematic Review of Occupational Exposure to... 6.2MB
https://ntp.niehs.nih.gov/ntp/ohat/oeccaaho/mgraph/occchemo_final20190300_508.pdf
... mitotic function inhibitors (e.g., vincristine), topoisomerase function inhibitors ... effects in workers occupationally exposed to vincristine with four genetic tests. ...
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Report: International Workshop on In Vitro Methods for Assessing... 25.4MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf
... Cytotoxic agents, such as 5-fluorouracil, vincristine, and cytosine arabinoside, cause ... NA NA 3.0 0.0068 440.47 0.0068 4 Vincristine sulfate 2068-78-2 0.01 0.000015 NA NA ...
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CERHR Monograph: Hydroxyurea 3.6MB
https://ntp.niehs.nih.gov/ntp/ohat/hydroxyurea/humonograph20090401.pdf
... arabinoside, vincristine, 6-thiogua- nine, prednisone, cepha- lothin, gentamicin, carbenicillin Acute myeloid leukemia; cytosine arabinoside, vincristine, 6-thiogua- nine, ...
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TOX-4: 1,2-Dichloroethane (Ethylene Dichloride) (CASRN 107-06... 4.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox004.pdf
NTP REPORT ON THE TOXICITY STUDIES OF 1,2-DICHLOROETHANE (ETHYLENE BICHLORIDE) IN F344/N RATS, SPRAGUE DAWLEY RATS, OSBORNE-MENDEL RATS, AND B6C3F 1 MICE (DRINKING WATER AND ...
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Background Review Document: Frog Embryo Teratogenesis Assay ... 2.4MB
https://ntp.niehs.nih.gov/iccvam/docs/fetax2000/brd/fetax-brd-all.pdf
... Tested Trichlorophenoxyacetic acid* Not Tested Not Tested Urethane** Tested Tested Vincristine sulfate* Not Tested Not Tested Vinyl chloride** Not Tested Not Tested Bolded ...
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TR-298: Dimethyl Morpholinophosphoramidate (CASRN 597-25-1) in... 10.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr298.pdf
8 TOXICOLOGY AND CARCINOGENESIS STUDIES OF DIMETHYL MORPHOLINOPHOSPHORAMIDATE (CAS NO. 597-2511) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN ...
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TR-310: Marine Diesel Fuel (NO CAS) and JP-5 Navy Fuel (CASRN... 10.1MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr310.pdf
10 TOXICOLOGY AND CARCINOGENESIS STUDIES OF MARINE DIESEL FUEL AND JP-5 NAVY FUEL (CAS NO. 8008-20-6) IN B6C3F1 MICE (DERMAL STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES ...
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TR-457: Salicylazosulfapyridine (CASRN 599-79-1) in F344 Rats... 18.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr457.pdf
... and the other group received vincristine sulfate, an aneuploidogen which .../kg) Trial 1 Triethylenemelamineb 1.o Vincristine sulfate' 0.125 Salicylazosulfapyridine ...
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TR-044 In Vitro Carcinogenesis: Guide to the Literature, Recent... 18.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr044.pdf
... Thiotepa Antitumor Antibiotics and Natural Products Actinomycin-D Bleomycin Vincristine Antimetabolites Methotrexate 6-Mercaptopurine Miscellaneous Synthetics Hycanthone ...
