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82 results found for "57-66-9".
  1. TR-395: Probenecid (CASRN 57-66-9) in F344/N Rats and B6C3F1Mice... 16.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr395.pdf

    NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 395 ~ ss~VlCC~s O .,~ ~ ' ~ " - ~ TOXICOLOGY AND CARCINOGENESIS STUDIES OF PROBENECID (CAS NO. 57-66-9) IN F344/N RATS AND ...

  2. Abstract for TR-395 64KB

    https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr395

    Abstract for TR-395 Toxicology and Carcinogenesis Studies of Probenecid in F344/N Rats and B6C3F1 (Gavage Studies) CASRN: 57-66-9 Chemical Formula: C13H19NO4S Molecular Weight: ...

  3. Target Organs and Levels of Evidence for TR-395 57KB

    https://ntp.niehs.nih.gov/data/tr/300s/tr395levels

    Target Organs and Levels of Evidence for TR-395 Toxicology and Carcinogenesis Studies of Probenecid (CASRN 57-66-9) in F344/N Rats and B6C3F1 Mice (Gavage Studies) Chemical (Study ...

  4. Minutes: BSC TRRS; Nov. 19, 1990 1.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1990/nov/trrs19nov1990mins_508.pdf

    D i r e c t B l u e Methyl Bromide M o n o c h l o r o a c e t i c A c i d Probenecid T i ... Long-Term S t u d i e s 103-90-2 7782-50-5 10599-90-3 2429-74-5 74-83-9 79-11-8 57-66-9 ...

  5. TR-384: 1,2,3-Trichloropropane (CASRN 96-18-4)in F344 Rats and... 5.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr384.pdf

    ... Hexachloroethane Phenylbutazone Probenecid Titanocene.2Cl 0/50 0/50 0/50 0/50 0/50 ... Hexachloroethane Phenylbutazone Probenecid Titanocene.2Cl 0/50 0/50 0/50 0/50 0/50 ...

  6. TOX-48: Allyl Acetate (CASRN 591-87-7), Allyl Alcohol (CASRN... 18.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox048.pdf

    ... inhibitor, but was unaffected by pretreatment with inhibitors of ADH, aldehyde dehydrogenase, or probenecid, a renal organic anion transporter inhibitor (Horvath eta!., 1992). ...

  7. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... NE No Evidence NE No Evidence NE No Evidence NE No Evidence TR-395 11/20/90 Probenecid 57-66-9 NE No Evidence NE No Evidence NE No Evidence SE Some Evidence TR-394 11/19/90 ...

  8. TR-426: Corn Oil, Safflower Oil, and Tricaprylin (CASRNs. 8001... 18.8MB

    https://ntp.niehs.nih.gov/go/tr426

    ... 0/50 0150 Phenylbutazone 3/50 0150 Probenecid 0150 0/50 Titanocene dichloride 0159 0/... 2/50 0150 Phenylbutazone 2/50 2/50 Probenecid 2/49 0/49 Titanocene dichloride 5/58 0/...

  9. TR-357: Hydrochlorothiazide (CASRN 58-93-5) in F344/N Rats and... 12.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr357.pdf

    ... Secretion is via the organic anion transport system in the proximal tubules and is Hydrochlorothiazide, NTP TR 357 14 I. INTRODUCTION sensitive to inhibition by probenecid (Gilman ...

  10. TR-446: 1-Trans-Delta9-Tetrahydrocannabinol (CASRN 1972-08-3... 16.4MB

    https://ntp.niehs.nih.gov/go/tr446

    ... Hexachloroethane Phenylbutazone Probenecid Promethazine Hydrochloride Titanocene ... Hexachloroethane Phenylbutazone Probenecid Promethazine Hydrochloride Titanocene ...

  11. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... Report TR-395 PDF (16.63 MB) Toxicology and Carcinogenesis Studies of Probenecid (CASRN 57-66-9) in F344/N Rats and B6C3F1 Mice (Gavage Studies) 1991 Technical Report TR-394 ...

  12. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... Report TR-395 PDF (16.63 MB) Toxicology and Carcinogenesis Studies of Probenecid (CASRN 57-66-9) in F344/N Rats and B6C3F1 Mice (Gavage Studies) 1991 Technical Report TR-394 ...

  13. TR-399: Titanocene Dichloride (CASRN 1271-19-8) in F344/N Rats... 8.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr399.pdf

    ... Hexachloroethane Phenylbutazone Probenecid Diglycidyl resorcinol ether Diglycidyl .../50 2/50 Phenylbutazone 0/50 O b 0 0/50 Probenecid 1/50 0/50 1/50 Diglycidyl resorcinol ...

  14. TR-450: Tetrafluoroethylene (CASRN 116-14-3) in F344 Rats and... 21.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr450.pdf

    ... by tetrafluoroethylene-mercapturic acid could be inhibited by probenecid, suggesting that the two tetrafluoroethylene compounds are transported by a different carrier system. ...

  15. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... TR-395 PDF (16.63 MB) Toxicology and Carcinogenesis Studies of Probenecid (CASRN 57-66-9) in F344/N Rats and B6C3F1 Mice (Gavage Studies) 1991 Long-Term ...

  16. RoC Background Document: Saccharin; Oct. 30-31, 1997 8.9MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/saccharin1_3apps_508.pdf

    ... 10 mg!kg) in the presence or absence of probenecid (competes for and inhibits renal tubular secretion of organic ions). Probenecid was administered (500 mg) 2 and 12 hours ...

  17. TR-356: Furosemide (CASRN 54-31-9) in F344/N Rats and B6C3F1Mice... 11.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr356.pdf

    ... W.M.M. (1979) Pharmacodynamic analy- sis of the furosemide-probenecid interaction in man. ... Ther. 229:440-446. 43. Hook, J.B.; Williamson, H.E. (1965) Influ- ence of probenecid and ...

  18. TR-569: Mixtures of 3'-Azido-3'-Deoxythymidine (AZT), Lamivudine... 7.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr569_508.pdf

    ... and its catabolites and interactions with probenecid in rhesus monkeys. Antimicrob. ... idation and renal excretion of zidovudine by probenecid in rats. J. Pharmacol. Exp. ...

  19. GMM-14: Genetically Modified Model Report on 3'-Azido-3'-Deoxythymidin... 3.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm14_508.pdf

    ... and its catabolites and interactions with probenecid in rhesus monkeys. Antimicrob. ... and renal excretion of zidovudine by probenecid in rats. J. Pharmacol. Exp. ...

  20. TR-522: Transplacental AZT (CASRN 30516-87-1) in Swiss (CD-1... 5.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr522.pdf

    ... and its catabolites and interactiosn with probenecid in rhesus monkeys. Antimicrob. ... and renal excretion of zidovudine by probenecid in rats. J. Pharmacol. Exp. ...

  21. GMM-16: Genetically Modified Model Report on Study of Mixtures... 5.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm16_508.pdf

    ... and its catabolites and interactions with probenecid in rhesus monkeys. Antimicrob. ... and renal excretion of zidovudine by probenecid in rats. J. Pharmacol. Exp. ...

  22. RoC Background Document: Tetrafluoroethylene; March 1999 4.5MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/tetrafluoroethylene1.pdf

    ... by tetrafluoroethylene-mercapturic acid could be inhib- ited by probenecid, suggesting that the two tetra- fluoroethylene compounds are transported by a different carrier system. ...

  23. TR-503: Chloral Hydrate (Ad Libitum and Dietary Controlled) ... 5.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr503.pdf

    ... Gavage 394 Acetaminophen Feed 395 Probenecid Gavage 396 Monochloroacetic Acid Gavage ... Toxicology and Carcinogenesis Studies of Probenecid (CAS No. 57-66-9) in F344/N Rats and ...

  24. TR-401: 2,4-Diaminophenol Dihydrochloride (CASRN 137-09-7) in... 12.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr401.pdf

    ... 060 0150 Phenylbutazone 0149 0149 0149 Probenecid 0149 0149 0149 Overall Historical ... 395 393 392 391 3 9 0 Probenecid Sodium Fluoride Chlorinated Water and ...

  25. TR-469: AZT (CASRN 30516-87-1) and AZT/a-Interferon A/D B6C3F1Mice... 15.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr469.pdf

    ... Pharmacokinetics of 3N-azido-3N-deoxythymidine and its catabolites and interactions with probenecid in rhesus monkeys. Antimicrob. Agents Chemother. 35, 801-807. Cretton, E.M., ...

  26. TR-417: p-Nitrophenol (CASRN 100-02-7) in Swiss Webster Mice... 7.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr417.pdf

    ... Fluoride 354 Dimethoxane 394 Acetaminophen 355 Diphenhydramine Hydrochloride 395 Probenecid 356 Furosemide 3% Monochloroacetic Acid 357 Hydrochlorothiazide 397 C.I. Direct Blue ...

  27. TR-444: Initiation/Promotion Study of o-Benzyl-p-Chlorophenol... 6.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr444.pdf

    ... Phosphate Chlorinated Water and Chloraminated Water Sodium Fluoride Acetaminophen Probenecid Monochloroacetic Acid C.I. Direct Blue 15 Polybrominated Biphenyls Titanocene ...

  28. TR-410: Naphthalene (CASRN 91-20-3) in B6C3F1Mice (Inhalation... 8.6MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr410.pdf

    ... 8-Methoxypsoralen Ochratoxin A Hydrochlorothiazide 395 393 392 391 390 Probenecid Sodium Fluoride Chlorinated Water and Chloraminated Water Tris(2-chloroethyl) ...

  29. TR-413: Ethylene Glycol (CASRN 107-21-1) in B6C3F1Mice (Feed... 11.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr413.pdf

    ... Fluoride 355 Diphenhydramine Hydrochloride 394 Acetaminophen 356 Furosemide 395 Probenecid 357 Hydrochlorothiazide 396 Monochloroacetic Acid 358 Ochratoxin A 397 C.I. Direct ...

  30. TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB

    https://ntp.niehs.nih.gov/go/tr518

    ... FF-1) (Feed) 398 Polysorbate 80 (Glycol) 415 Polyvinyl Alcohol 474 Primidone 476 Probenecid 395 Promethazine Hydrochloride 425 Propylene 272 Propylene Glycol Mono-t-butyl Ether ...

  31. TR-400: 2,3-Dibromo-1-Propanol (CASRN 96-13-9) in F344/N Rats... 11.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr400.pdf

    ... Fluoride 348 a-Methyldopa Sesquihydrate 394 Acetaminophen 349 Pentachlorophenol 395 Probenecid 350 Tribromomethane 3% Monochloroacetic Acid 35 1 p-Chloroaniline Hydrochloride 397 ...

  32. TR-412: 4,4'-Diamino-2,2'-Stilbenedisulfonic Acid Disodium Salt... 11.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr412.pdf

    ... Water and Chloraminated Water W i u m Huoride Probenecid Monahlomcetic Acid "itanusme Dichloride 2.4-Diaminophenol Dihydmhloride Resorcinol C.I. Acid Red 114 +Wymlactone C I . ...

  33. TR-385: Methyl Bromide (CASRN 74-83-9) in B6C3F1Mice (Inhalation... 7.3MB

    https://ntp.niehs.nih.gov/go/tr385

    ... 3,3-Dimethylbenzidine Dihydrochloride Tris(2-chloroethyl) Phosphate Sodium Fluoride Probenecid 362 363 364 365 4-Vinyl-1-Cyclohexene Diepoxide Bromoethane (Ethyl Bromide) ...

  34. TR-388: Ethylene Thiourea (CASRN 96-45-7) in F344 Rats and B6C3F1Mice... 13.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr388.pdf

    ... Hexachbmethane 391 393 3% Tris(2chloroethyl) Phosphate Sodium Fluoride Probenecid 362 363 364 365 4-Vinyl-l -Cydohexene Diepaxide Bromoethane (Ethyl Bromide) ...

  35. TR-397: C.I. Direct Blue 15 (CASRN 2429-74-5) in F344 Rats (Drinking... 13.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr397.pdf

    ... 8-Methcaypsoralen 399 3% 395 Titanocene Dichloride Monochloroacetic Acid Probenecid 370 369 368 367 366 365 364 363 362 Benzofuran Alpha-Methylbenzyl Alcohol Nalidixic ...

  36. TR-405: C.I. Acid Red 114 (CASRN 6459-94-5) in F344/N Rats (Drinking... 12.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr405.pdf

    ... Dihydrochloride 391 Tris(2chlomethyl) Phosphate 393 Sodium Fluoride . 395 Probenecid 399 Titanocene Dichloride These N T P Technical Reports are available for sale from ...

  37. TR-406: g-Butyrolactone (CASRN 96-48-0) in F344/N Rats and B6C3F1Mice... 11.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr406.pdf

    ... 361 360 359 Hacscbloroethane N,N-Dimethyianiline S-MethoJrypsoralen 395 393 391 Probenecid Sodium Fluoride Tris(2chlorcethyl) Phosphate 365 364 363 362 Pentaerythritol ...

  38. TR-408: Mercuric Chloride (CASRN 7487-94-7) in F344 Rats and... 12.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr408.pdf

    ... Phosphate Chlorinated Water and Chloraminated Water Sodium Fluoride Acetaminophen Probenecid Monochloroacetic Acid C.I. Direct Blue 15 Titanocene Dichloride 2,4-Diaminophenol ...

  39. TR-414: Pentachloroanisole (CASRN 1825-21-4) in F344 Rats and... 15.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr414.pdf

    ... Fluoride 354 Dimethoxane 394 Acetaminophen 355 Diphenhydramine Hydrochloride 395 Probenecid 356 Furosemide 3% Monuchloroacetic Acid 357 Hydmhlorothiazide 397 C.I. Direct Blue ...

  40. TR-479: Coconut Oil Acid Diethanolamine Condensate (CASRN 68603... 7.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr479.pdf

    ... FF-1) (Feed) 398 Polysorbate 80 (Glycol) 415 Polyvinyl Alcohol 474 Primidone 476 Probenecid 395 Promethazine Hydrochloride 425 Propylene 272 1,2-Propylene Oxide 267 Propyl ...

  41. TR-502: Chloral Hydrate (CASRN 302-17-0) in B6C3F1Mice (Gavage... 8.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr502.pdf

    ... FF-1) (Feed) 398 Polysorbate 80 (Glycol) 415 Polyvinyl Alcohol 474 Primidone 476 Probenecid 395 Promethazine Hydrochloride 425 Propylene 272 1,2-Propylene Oxide 267 Propyl ...

  42. TR-394: Acetaminophen (CASRN 103-90-2) in F344 Rats and B6C3F1Mice... 14.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr394.pdf

    ... Water 355 Diphenhydramine Hydrochloride 393 Sodium Fluoride 356 Furosemide 395 Probenecid 357 Hydrochlorothiazide 3% Monochloroacetic Acid 358 Ochratoxin A 397 C.I. Direct ...

  43. TR-398: Polybrominated Biphenyls (CASRN 67774-32-7)(Firemaster... 14.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr398.pdf

    ... Fluoride 352 N-Methylolacrylamide 394 Acetaminophen 353 2,4-Diehlorophenol 395 Probenecid 354 Dimethoxane 396 Monochloroacetic Acid 355 Diphenhydramine Hydrochloride 397 C.I. ...

  44. TR-402: Furan (CASRN 110-00-9) in F344 Rats and B6C3F1 Mice(Gavage... 31.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr402.pdf

    ... Chloraminated Water 356 Furosemide 393 Sodium Fluoride 357 Hydrochlorothiazide 395 Probenecid 358 Ochratoxin A 396 Monochloroacetic Acid 359 8-Methoxypsoralen 397 C.I. Direct ...

  45. TR-403: Resorcinol (CASRN 108-46-3) in F344 Rats and B6C3F1Mice... 15.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr403.pdf

    ... Water 359 8-Methoxypaoralen 393 Sodium Fluoride 360 N,N-Dimethylaniline 395 Probenecid 361 Hexachloroethane 396 Monochloroacetic Acid 362 4-Vinyl-l-Cyclohexene Diepoxide ...

  46. TR-404: 5,5-Diphenylhydantoin (CASRN 57-41-0) (Phenytoin) in... 16.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr404.pdf

    ... Fluoride 348 a-Methyldopa Sesquihydrate 394 Acetaminophen 349 Pentachlorophenol 395 Probenecid 350 Tribromomethane 396 Monochloroacetic Acid 351 p-Chloroaniline Hydrochloride 397 ...

  47. TR-407: C.I. Pigment Red 3 (CASRN 2425-85-6) in F344/N Rats and... 15.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr407.pdf

    ... Furosemide Diphenhydramine Hydrochloride 395 393 391 390 389 387 386 Probenecid Sodium Fluoride Tris(2chloroethyl) Phosphate 3 , 3 '-Dimethylbenzidine ...

  48. TR-411: C.I. Pigment Red 23 (CASRN 6471-49-4) in F344 Rats and... 15.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr411.pdf

    ... Thiourea 358 357 Ochratoxin A Hydrochlorothiazide 3% 395 Monochloroacetic Acid Probenecid 361 360 359 Hexachloroethane N,N-Dimethylaniline 8-Methoxypsoralen 401 399 397 ...

  49. TR-421: Talc (CASRN 14807-96-6)(Non-Asbestiform) in F344/N Rats... 16.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr421.pdf

    ... 392ChlorinatedWaterandChloraminatedWater 393 Sodium Fluoride 394 Acetaminophen 395 Probenecid 3% Monochloroacetic Acid 397 C.I. DirectBlue15 398 Polybrominated Biphenyls 399 ...

  50. TR-424: o-Benzyl-p-Chlorophenol (CASRN 120-32-1) in F344/N Rats... 15.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr424.pdf

    ... Rmrsone 393 W i u m Fluoride 346 Chloroethane 394 Acetaminophen 347 D-Limonene 395 Probenecid 348 a-Methyldopa Sesquihydrate 3% Monochloroacetic Acid 349 Pentachlorophenol 397 ...

 
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