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Addendum to ICCVAM Evaluation of In Vitro Test Methods for Detecting... 2.9MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edaddendfinal.pdf
... ER+++ ER#- Y ** strong ER agonist; being considered for testing in vivo by EPA Apomorphine 58-00-4 Heterocyclic Compound Pharmaceutical, Veterinary Agent † - - Y IM dopamine D1/...
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ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential... 10.6MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edfinalrpt0503/edfinrpt.pdf
... Hormone Apigenin 520-36-5 Flavanoid; Flavone; Phenol Natural product Apomorphine 58-00-4 Heterocycle; Quinoline Pharmaceutical Atrazine 1912-24-9 Aromatic amine; ...
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NICEATM Validation Study Report on the MCF-7 Cell Proliferation... 1.8MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/mcf7/mcf7-valstudyreport-19jun12-wcv2-draft.pdf
... perchlorate NEG (1/1) NT NEG 4 Apomorphine NEG (1/1) NT NEG 4 Bicalutamide NEG (1/... perchlorate POS (1/1) NEG (1/1) NEG 4 Apomorphine POS (1/1) NEG (1/1) NEG 4 Bicalutamide ...
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CERHR Monograph: Amphetamines 4.1MB
https://ntp.niehs.nih.gov/ntp/ohat/stimulants/amphetamines/amphetaminemonograph.pdf
... rat.].Injection.ip.or.iv.with.apomorphine.significantly.inhibited. dopaminergic. ... 1 /D 2 .antagonist,.consistently.reversed.apomorphine- induced.inhibition.at.all.ages.. ...
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ICCVAM Test Method Evaluation Report on the BG1Luc ER TA Test... 17.5MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/bg1lucer-ta-tmer-combined.pdf
... Natural Product, Pharmaceutical Intermediate >99.0 Sigma-Aldrich Corporation Apomorphine 58-00-4 Heterocyclic Compound Pharmaceutical, Veterinary Agent 99.8 Sigma-Aldrich ...
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CERHR Monograph: Potential Human Reproduction Effects of Styrene 6.0MB
https://ntp.niehs.nih.gov/ntp/ohat/styrene/styrene_monograph.pdf
... stimulated.locomotor.activity.and.apomorphine-induced.stereotypy.were.assessed.in.8.a....locomotor.activity.and.an.increase.in.apomorphine-induced.stereotypy. ...
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XDS Submission of the LUMI-CELL ER Test Method 3.2MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/iccvamsubmission28jan05.pdf
... Compounds on ICCVAM list not completed with explinations. Anastrazole 120511-73-1 P - - - - Not commercially available Apomorphine 58-00-4 PP - - - - Controlled Substance Bisphenol ...
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Submission of XDS's LUMI-CELL ER High-Throughput System for Screening... 2.4MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexa/xds-sub.pdf
... Compounds on ICCVAM list not completed with explinations. Anastrazole 120511-73-1 P - - - - Not commercially available Apomorphine 58-00-4 PP - - - - Controlled Substance Bisphenol ...
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TR-387: dl-Amphetamine Sulfate (CASRN 60-13-9) in F344/N Rats... 10.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr387.pdf
... Teratology 20, 403-411. Kuczenski, R., Segal, D.S.,k i t h , N.J., and Applegate, C.D. (1987). Effects of amphetamine, methylphenidate, and apomorphine on regional brain serotonin ...
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TR-455: Codeine (CASRN 76-57-3) in F344 Rats and B6C3F1Mice ... 15.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr455.pdf
NATION& TOXICOLOGY PROGRAM Technical Report Series No. 455 TOXICOLOGY A N D CARCINOGENESIS STUDIES OF CODEINE (CAS NO. 76-57-3) . - . ~. . IN F344/NRATS AND B6C3Fl MICE (FEED ...
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TR-380: l-Epinephrine Hydrochloride (CASRN 55-31-2) in F344/N... 21.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr380.pdf
... Science 224: 1198-1206. 143. Suter, W.; Matter-Jaeger, I. (1984) Gena- toxicity of apomorphine and various cate- cholamines in the Salmonella mutagenicity test (Ames test) and in ...
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CERHR Monograph: Potential Human Reproductive and Developmental... 6.3MB
https://ntp.niehs.nih.gov/ntp/ohat/bisphenol/bisphenol.pdf
... N,. Koshikawa.N.(2007).J Oral Sci..Behav- ioral. responses. to. methylphenidate. and. apomorphine.in.rats.exposed.neonatally. to.bisphenol-A..49:311.-.318. 148..Narita.M,.Miyagawa....
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Monograph on Potential Human Reproductive and Developmental Effects... 2.4MB
https://ntp.niehs.nih.gov/ntp/ohat/fluoxetine/fluoxetine_monograph.pdf
... challenge dose of 10 mg/kg fluoxetine or 1 mg/kg apomorphine, respectively. ... challenged with fluoxetine or apomorphine (148); behavior in adult offspring ...
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TR-411: C.I. Pigment Red 23 (CASRN 6471-49-4) in F344 Rats and... 15.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr411.pdf
TOXICOLOGY PROGRAM Technical Report Series No.411 TOXICOLOGY AND CARCINOGENESIS STUDIES OF C.I. PIGMENT RED 23 (CASNO. 6471-49-4) IN F344 RATS AND B6C3Fl MICE (FEED STUDIES) U.S. ...
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CERHR Monograph: Soy Infant Formula 122.6MB
https://ntp.niehs.nih.gov/ntp/ohat/genistein-soy/soyformula/soymonograph2010_508.pdf
... This effect showed a signifcant correlation with manganese intake in the frst 2 weeks of life. Behavioral response to apomorphine injection was also correlated with manganese ...
