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Search suggestions for "58-55-9".

  1. CEBS Data Related to Theophylline (58-55-9) https://cebs.niehs.nih.gov/cebs/test_article/58-55-9


57 results found for "58-55-9".

  1. TR-473: Theophylline (CASRN 58-55-9) in F344/N Rats and B6C3F1Mice... 11.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr473.pdf

    OF THEOPHYLLINE (CAS NO. 58-55-9) IN F344/N RATS AND B6C3F MICE 1 (FEED AND GAVAGE STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 August 1998 ...

  2. Abstract for TR-473 77KB

    https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr473

    Abstract for TR-473 Toxicology and Carcinogenesis Studies of Theophylline in F344/N Rats and B6C3F1 Mice (Feed and Gavage Studies) CASRN: 58-55-9 Chemical Formula: C7H8N4O2 ...

  3. Abstract for TER84110 64KB

    https://ntp.niehs.nih.gov/publications/abstracts/dev/ter84110

    Abstract for TER84110 Teratologic Evaluation of Theophylline Administered to CD Rats on Gestational Days 6 Through 15 CASRN: 58-55-9 Chemical Formula: C7H8N4O2 Molecular Weight: ...

  4. Abstract for RACB84074 61KB

    https://ntp.niehs.nih.gov/publications/abstracts/repro/racb84074

    Abstract for RACB84074 Theophylline: Reproduction and Fertility Assessment in CD-1 Mice When Administered in Drinking Water/Feed CASRN: 58-55-9 Chemical Formula: C7H8N4O2 Molecular ...

  5. Abstract for TER84111 64KB

    https://ntp.niehs.nih.gov/publications/abstracts/dev/ter84111

    Abstract for TER84111 Teratologic Evaluation of Theophylline Administered to CD-1 Mice on Gestational Days 6 Through 15 CASRN: 58-55-9 Chemical Formula: C7H8N4O2 Molecular Weight: ...

  6. Target Organs and Levels of Evidence for TR-473 60KB

    https://ntp.niehs.nih.gov/data/tr/400s/tr473levels

    Target Organs and Levels of Evidence for TR-473 Toxicology and Carcinogenesis Studies of Theophylline (CASRN 58-55-9) in F344/N Rats and B6C3F1 Mice (Feed and Gavage Studies) ...

  7. Minutes: BSC TRRS; Dec. 11, 1996 1.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1996/dec/trrs11dec1996mins_508.pdf

    Intravaginal Primidone 125-33-7 Feed Tetrahydrofuran 109-99-9 Inhalation Theophylline 58-55-9 Gavage Long-Term Studies 2 DRAFr SUMMARY MINUTES NTP TECHNICAL REPORTS REVIEW ...

  8. Studies on Historical Control Reports for NIH-07 Feed 312KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/nih-07_1999/histcont_1999_by_list_of_studies_508.pdf

    Rats Fischer344 Gavage Corn Oil Theophylline Rats Fischer344 Gavage Methylcellulose ... Mice B6C3F1 Gavage Corn Oil Theophylline Mice B6C3F1 Gavage Methylcellulose ...

  9. The Development of a 96-well Plate-Based Model of the Human Intestinal... 2.3MB

    https://ntp.niehs.nih.gov/sites/default/files/2023-12/Wksp_09_Bill Thelin_GutModels2023_508.pdf

    ... Ranitidine Losartan Terbutaline Enalapril Maleate Verapamil Theophylline 15 DMPK Towards functional DMPK Testing Measured Quantitative Intestinal Drug Absorption and Efflux . ...

  10. National Institute of Environmental Health Sciences: Pei-Li Yao... 157KB

    https://www.niehs.nih.gov/research/atniehs/dtt/assoc/opo/staff/yao

    ... (2005). Global expression profiling of theophylline response genes in macrophages: ... (2005). Global expression profiling of theophylline response genes in macrophages: ...

  11. Reproductive Abstracts 202KB

    https://ntp.niehs.nih.gov/publications/abstracts/repro

    ... in CD-1 Mice When Administered in Drinking Water 1985 Reproductive RACB84074 Theophylline Theophylline (CASRN: 58-55-9): Reproduction and Fertility Assessment in CD-1 Mice When ...

  12. Study Abstracts 375KB

    https://ntp.niehs.nih.gov/publications/abstracts

    ... in CD-1 Mice When Administered in Drinking Water 1985 Reproductive RACB84074 Theophylline Theophylline (CASRN: 58-55-9): Reproduction and Fertility Assessment in CD-1 Mice When ...

  13. Nomination Background: d-Pseudoephedrine (CASRN: 90-82-4) 388KB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/ephedrinealkaloids_508.pdf

    ... Ephedrine was not found to affect theophylline clearance (CANTOX, 2000; Upton, 1991). ... as well as trace amounts of theophylline (500-750 ppm) and theobromine (300-500 ppm). ...

  14. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    .../Sex NT Chemical Not Tested in Species/Sex NE No Evidence TR-473 12/11/96 Theophylline 58-55-9 NE No Evidence NE No Evidence NE No Evidence NE No Evidence TR-472 12/12/96 ...

  15. Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf

    ... Tolbutamide 1.81 9.62 2601.1 105 21 Theophylline 1.83 3.33 600.0 261 3 Ferrous sulfate ... 279 Thioacetamide 4.17 4.01 301.3 280 Theophylline sodium acetate 4.19 2.22 582.2 281 ...

  16. Report: International Workshop on In Vitro Methods for Assessing... 25.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf

    ... 0.31 104 Tolbutamide 64-77-7 489.39 1.81 NA NA 2601.1 9.62 270.38 9.62 105 21 Theophylline 58-55-9 329.75 1.83 NA NA 600.0 3.33 180.19 3.33 108 Registry of Cytotoxicity Data ...

  17. RoC Background Document: Ethylene Oxide; Dec. 2-3, 1998 4.0MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/ethyloxide_oneapp_508.pdf

    ... and theophylline, which were added to the preincubation mixture. Erythrocytes enhanced the mutagenic activity of ethylene oxide by two- to fourfold, while theophylline ...

  18. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... 1998 Technical Report TR-473 PDF (11.3 MB) Toxicology and Carcinogenesis Studies of Theophylline in F344/N Rats and B6C3F1 Mice (Feed and Gavage Studies) 1998 Technical Report ...

  19. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... Carcinogenicity TR-473 PDF (11.3 MB) Toxicology and Carcinogenesis Studies of Theophylline in F344/N Rats and B6C3F1 Mice (Feed and Gavage Studies) 1998 Long-Term ...

  20. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... 1998 Technical Report TR-473 PDF (11.3 MB) Toxicology and Carcinogenesis Studies of Theophylline in F344/N Rats and B6C3F1 Mice (Feed and Gavage Studies) 1998 Technical Report ...

  21. Minutes: BSC; March 14, 1983 2.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1983/march/bsc_mins19830314_508.pdf

    ... H e c i t e d an example of such a study i n the c l i n i c a l l i t e r a t u r e with theophylline. Dr. Schwetz said the F344 r a t would be used and described the experimental ...

  22. Minutes: BSC; April 17, 1996 335KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1996/april/19960417_bsc_508.pdf

    ... (AZT)/interferon (IFN), chloroprene, cobalt sulfate, ethylbenzene, isobutyraldehyde, oxazepam, polyvinyl alcohol, primaclone, tetrahydrofuran, and theophylline. ...

  23. TR-509: 2,4-Hexadienal (89% trans,trans Isomer, CASRN 142-83... 10.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr509.pdf

    ... Salicylazosulfapyridine 1/50 0/50 1/50 Theophylline 0/50 0/50 0/50 Overall Historical ... Salicylazosulfapyridine 0/50 0/50 0/50 Theophylline 0/50 0/50 0/50 Overall Historical ...

  24. Background: Dimethylethanolamine (DMAE) [108-01-0] and Selected... 1.3MB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/dmae_update_110002_508.pdf

    ... Most of the drugs listed are herbal and/or used in dietary supplements. The example was for a composition containing theophylline for "promoting cellulite removal." Johnson and ...

  25. TR-585: Green Tea Extract in F344/NTac Rats and B6C3F1/N Mice... 3.6MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr585_508.pdf

    ... Caffeine 3.7 4.9 1.63 1.28-4.05 1.10-17.4 2.6-3.8 Theobromine 0.08 NM NA NA NA NA Theophylline 0.008 NM NA NA NA NA Polyphenol Gallic acid 0.32 NM 2.74 NA NA 0.0-0.2 Amino acid ...

  26. TR-585: Green Tea Extract in F344/NTac Rats and B6C3F1/N Mice... 3.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr585_508.pdf

    ... Caffeine 3.7 4.9 1.63 1.28-4.05 1.10-17.4 2.6-3.8 Theobromine 0.08 NM NA NA NA NA Theophylline 0.008 NM NA NA NA NA Polyphenol Gallic acid 0.32 NM 2.74 NA NA 0.0-0.2 Amino acid ...

  27. TOX-13: Trinitrofluorenone (CASRN 129-79-3) 2.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox013.pdf

    ... A similar vascular lesion has been reported following treatment of rats with theophylline ... administered (gavage and dosed-feed) theophylline in Fischer 344 rats and B6C3F 1 mice. ...

  28. Public Comment: 2-Butoxyethanol (Attachment); Seth Barna; RoC... 758KB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2013/publiccomm/barna_attachmentacc_508be.pdf

    ... Biocompatibility study of theophylline/chitosan/beta- cyclodextrin microspheres as ... To evaluate the biocompatibility of the theophylline/chitosan/beta-cyclodextrin ...

  29. Background Review Document: Frog Embryo Teratogenesis Assay ... 2.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/fetax2000/brd/fetax-brd-all.pdf

    ... Dichloroacetate + + - Phenytoin + + - Theophylline + + - Trichloroacetic acid + + - 6-46 ... + - 0.38 Sodium iodoacetate - - 0.42 Theophylline No + -+ 0.46 Caffeine No + + 0.68 ...

  30. GMM-02: Genetically Modified Model Report on Acesulfame Potassium... 2.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm02_508.pdf

    ... HPLC. Samples of the formulation were extracted with 50:50 water/methanol, shaken for 10 minutes, and then centrifuged; theophylline (2 mg/mL) was used as an internal standard. ...

  31. TR-482: Furfural Alcohol (CASRN 98-00-0) in F344/N Rats and B6C3F1... 27.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr482.pdf

    ... Guidelines for combining neoplasms for evaluation of rodent carcinogenesis studies. JNCI 76, 283-289. McFee, A.F. (1991). Chromosomal effects of theophylline measured in mouse bone ...

  32. RoC Background Document: Cyclosporin A; Nov. 18-19, 1996 4.9MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/cyclosporin_a1_508.pdf

    ... This patient's treatment had included cyclosporin (2.6 mg/kg/day), minoxidil, captopril, furosemide, prednisone, and theophylline. The duration of exposure to cyclosporin was not ...

  33. TR-471: Cobalt Sulfate Heptahydrate (CASRN 10026-24-1) in F344... 13.1MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr471.pdf

    ... Toxicology and Carcinogenesis Studies of Theophylline (CAS No. 58-55-9) in F344/N Rats and B6C3F Mice (Feed and Gavage Studies). Technical Report Series 1 No. 473. NIH Publication ...

  34. TR-464: Technical Grade Sodium Xylene Sulfonate (CASRN 1300-72... 9.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr464.pdf

    ... Toxicology and Carcinogenesis Studies of Theophylline (CAS No. 58-55-9) in F344/N Rats and B6C3F Mice (Feed and Gavage Studies). Technical Report Series 1 No. 473. NIH Publication ...

  35. TR-471: Cobalt Sulfate Heptahydrate (CASRN 10026-24-1) in F344... 9.0MB

    https://ntp.niehs.nih.gov/sites/default/files/2023-08/tr471_508.pdf

    ... Toxicology and Carcinogenesis Studies of Theophylline (CAS No. 58-55-9) in F344/N Rats and B6C3F 1 Mice (Feed and Gavage Studies). Technical Report Series No. 473. NIH Publication ...

  36. TR-449: Triethanolamine (CASRN 102-71-6) in F344 Rats and B6C3F1Mice... 10.1MB

    https://ntp.niehs.nih.gov/go/tr449

    ... Toxicology and Carcinogenesis Studies of Theophylline (CAS No. 58-55-9) in F344/N Rats and B6C3F Mice (Feed and Gavage Studies). Technical Report Series 1 No. 473. NIH Publication ...

  37. TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB

    https://ntp.niehs.nih.gov/go/tr518

    ... Sulfate 296 Tetrakis(Hydroxymethyl)Phosphonium Chloride 296 Tetranitromethane 386 Theophylline 473 4,4-Thiobis(6-t-Butyl-m-Cresol) 435 Titanocene Dichloride 399 Chemical TR No. ...

  38. TOX-67: 2-Methylimidazole and 4-Methylimidazole 5.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox067.pdf

    ... The solvent program was 75:25 A:B (isocratic) for 35 minutes, then to 100% B in 55 minutes. Theophylline and caffeine were used as internal standards. For lot 323734/1 193, Karl ...

  39. TR-467: Chloroprene (CASRN 126-99-8) in F344/N Rats and B6C3F1Mice... 14.5MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr467.pdf

    ... Toxicology and Carcinogenesis Studies of Theophylline (CAS No. 58-55-9) in F344/N Rats and B6C3F Mice (Feed and Gavage Studies). Technical Report Series 1 No. 473. NIH Publication ...

  40. TR-491: Methyleugenol (CASRN 93-15-2) in F344/N Rats and B6C3F1Mice... 22.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr491.pdf

    ... Toxicology and Carcinogenesis Studies of Theophylline (CAS No. 58-55-9) in F344/N Rats and B6C3F 1 Mice (Feed and Gavage Studies). Technical Report Series No. 473. NIH Publication ...

  41. ICCVAM Background Review Document (Vol 2): In Vitro Cytotoxicity... 61.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol2_nov2006.pdf

    ... TESS, EPA, NTP Pesticide (nematocide) Theophylline 600 b MEIC, RC, TESS, NTP ... VI 261.98 0.00093 0.24 0.19 49.8 Theophylline sodium acetate 262.23 4.19 1098.7 2.22 ...

  42. TR-469: AZT (CASRN 30516-87-1) and AZT/a-Interferon A/D B6C3F1Mice... 15.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr469.pdf

    ... Toxicology and Carcinogenesis Studies of Theophylline (CAS No. 58-55-9) in F344/N Rats and B6C3F Mice (Feed and Gavage Studies). Technical Report Series 1 No. 473. NIH Publication ...

  43. TR-479: Coconut Oil Acid Diethanolamine Condensate (CASRN 68603... 7.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr479.pdf

    ... Sulfate 296 Tetrakis(Hydroxymethyl)Phosphonium Chloride 296 Tetranitromethane 386 Theophylline 473 4,4-Thiobis(6-t-Butyl-m-Cresol) 435 Titanocene Dichloride 399 Toluene 371 2,4- ...

  44. TR-502: Chloral Hydrate (CASRN 302-17-0) in B6C3F1Mice (Gavage... 8.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr502.pdf

    ... Sulfate 296 Tetrakis(Hydroxymethyl)Phosphonium Chloride 296 Tetranitromethane 386 Theophylline 473 4,4-Thiobis(6-t-Butyl-m-Cresol) 435 Titanocene Dichloride 399 Toluene 371 2,4- ...

  45. TR-498: p-Nitrotoluene (CASRN 99-99-0) in F344/N Rats and B6C3F1Mice... 10.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr498.pdf

    ... Sulfate 296 Tetrakis(Hydroxymethyl)Phosphonium Chloride 296 Tetranitromethane 386 Theophylline 473 4,4-Thiobis(6-t-Butyl-m-Cresol) 435 Titanocene Dichloride 399 Toluene 371 2,4- ...

  46. TR-508: Riddelliine (CASRN 23246-96-0) in F344/N Rats and B6C3F1Mice... 9.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr508.pdf

    ... Sulfate 296 Tetrakis(Hydroxymethyl)Phosphonium Chloride 296 Tetranitromethane 386 Theophylline 473 4,4-Thiobis(6-t-Butyl-m-Cresol) 435 Titanocene Dichloride 399 Toluene 371 2,4- ...

  47. TR-511: Dipropylene Glycol (CASRN 25265-71-8) in F344/N Rats... 10.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr511.pdf

    ...kis(Hydroxymethyl)Phosphonium Sulfate 296 Tetrakis(Hydroxymethyl)Phosphonium Chloride 296 Tetranitromethane 386 Theophylline 473 4,4-Thiobis(6-t-Butyl-m-Cresol) 435 Chemical TR No. ...

  48. TR-512: Elmiron (CASRN 37319-17-8) in F344/N Rats and B6C3F1Mice... 12.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr512.pdf

    ... Tetrakis(Hydroxymethyl)Phosphonium Sulfate 296 Tetrakis(Hydroxymethyl)Phosphonium Chloride 296 Tetranitromethane 386 Theophylline 473 4,4-Thiobis(6-t-Butyl-m-Cresol) 435 Titanocene ...

  49. TR-513: Decalin (CASRN 91-17-8) in F344/N Rats and B6C3F1Mice... 11.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr513.pdf

    ... Tetrakis(Hydroxymethyl)Phosphonium Sulfate 296 Tetrakis(Hydroxymethyl)Phosphonium Chloride 296 Tetranitromethane 386 Theophylline 473 4,4-Thiobis(6-t-Butyl-m-Cresol) 435 Titanocene ...

  50. TR-514: trans-Cinnamaldehyde (Microencapsulated) (CASRN 14371... 8.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr514.pdf

    ... Sulfate 296 Tetrakis(Hydroxymethyl)Phosphonium Chloride 296 Tetranitromethane 386 Theophylline 473 4,4-Thiobis(6-t-Butyl-m-Cresol) 435 Titanocene Dichloride 399 Toluene

 
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