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TR-357: Hydrochlorothiazide (CASRN 58-93-5) in F344/N Rats and... 12.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr357.pdf
7 TOXICOLOGY AND CARCINOGENESIS STUDIES OF HYDROCHLOROTHIAZIDE (CAS NO. 58-93-5) IN F344/N RATS AND B6C3Fi MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public ...
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Abstract for TR-357 67KB
https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr357
Abstract for TR-357 Toxicology and Carcinogenesis Studies of Hydrochlorothiazide in F344/N Rats and B6C3F1 Mice (Feed Studies) CASRN: 58-93-5 Chemical Formula: C7H8ClN3O4S2 ...
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Abstract for TER84084 61KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter84084
Abstract for TER84084 Teratologic Evaluation of Hydrochlorothiazide Administered to CD® Rats on Gestational Days 6 through 15 CASRN: 58-93-5 Chemical Formula: C7H8ClN3O4S2 ...
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Abstract for TER84085 62KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter84085
Abstract for TER84085 Teratologic Evaluation of Hydrochlorothiazide Administered to CD-1 Mice on Gestational Days 6 Through 15 CASRN: 58-93-5 Chemical Formula: C7H8ClN3O4S2 ...
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Target Organs and Levels of Evidence for TR-357 57KB
https://ntp.niehs.nih.gov/data/tr/300s/tr357levels
Target Organs and Levels of Evidence for TR-357 Toxicology and Carcinogenesis Studies of Hydrochlorothiazide (CASRN 58-93-5) in F344/N Rats and B6C3F1 Mice (Feed Studies) Chemical ...
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TR-357 Pathology Tables and Curves 56KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr357
3 TR-357 Pathology Tables and Curves TR-357 HYDROCHLOROTHIAZIDE Pathology Tables Tumor and Non-tumor Pathology Tables are not Available Growth and Survival Curves - Rats Male and ...
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Minutes: BSC TRRS; April 18, 1988 4.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1988/apr/88apr18trrsmins_508.pdf
Hart, (919) 541-3971; FTS1 629-3971. ~TENTS Tecmical Reports CAS No. p-Chloroan!Une !06-47-8 2,4-0ichlorophenol 120-83-2 Furosemide 54-31-9 Hydrochlorothiazide 58-93-5 d-Umonene ...
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TR-420: Triamterene (CASRN 396-01-0) in F344/N Rats and B6C3F1Mice... 20.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr420.pdf
... U C T I O N other diuretics (e.g., hydrochlorothiazide) that act at Triamterene has been ... o f edema both triamterene hydrochlorothiazide and are associated with congestive ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... in Species/Sex NT Chemical Not Tested in Species/Sex TR-357 04/18/88 Hydrochlorothiazide 58-93-5 NE No Evidence NE No Evidence EE Equivocal Evidence NE No Evidence TR-356 04/...
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TR-348: alpha-Methyldopa Sesquihydrate (CASRN 41372-08-1) in... 10.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr348.pdf
... hydrochloride) is used for intravenous injection; a combination of methyl- dopa and hydrochlorothiazide is available as tablets (USP, 1985;Remington's, 1985;PDR, 1988). ...
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Minutes: BSC; Dec. 9-10, 2014 270KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2014/dec/bsc_dec2014_minutes_508.pdf
... Recent nominations include the flame retardants Firemaster 550 and decabromodiphenylethane; hydrochlorothiazide, a widely prescribed diuretic to treat hypertension; and the January ...
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Technical Reports 903KB
https://ntp.niehs.nih.gov/publications/reports/tr
... TR-357 PDF (12.08 MB) Toxicology and Carcinogenesis Studies of Hydrochlorothiazide (CASRN 58-93-5) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1989 Technical Report TR-356 ...
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TR-356: Furosemide (CASRN 54-31-9) in F344/N Rats and B6C3F1Mice... 11.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr356.pdf
... Another diuretic, hydrochlorothiazide, has also been studied by the NTP by the feed route, ... Two other feed studies (hydrochlorothiazide, NTP, 1989a, and diphenhydramine hydrochlo- ...
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Toxicology/Carcinogenicity 1.1MB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox
... TR-357 PDF (12.08 MB) Toxicology and Carcinogenesis Studies of Hydrochlorothiazide (CASRN 58-93-5) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1989 Long-Term ...
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Study Reports 1.1MB
https://ntp.niehs.nih.gov/publications/reports
... TR-357 PDF (12.08 MB) Toxicology and Carcinogenesis Studies of Hydrochlorothiazide (CASRN 58-93-5) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1989 Technical Report TR-356 ...
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TR-417: p-Nitrophenol (CASRN 100-02-7) in Swiss Webster Mice... 7.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr417.pdf
... Hydrochloride 395 Probenecid 356 Furosemide 3% Monochloroacetic Acid 357 Hydrochlorothiazide 397 C.I. Direct Blue 15 358 Ochratoxin A 3 9 Titanocene Dichloride 359 ...
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TR-444: Initiation/Promotion Study of o-Benzyl-p-Chlorophenol... 6.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr444.pdf
... 2,4-Dichlorophenol Dimethoxane Diphenhydramine Hydrochloride Furosemide Hydrochlorothiazide Ochratoxin A 8-Methoxypsoralen N,N-Dimethylaniline Hexachloroethane ...
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TR-410: Naphthalene (CASRN 91-20-3) in B6C3F1Mice (Inhalation... 8.6MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr410.pdf
... 359 358 357 Hexachloroethane N,N-Dimethylaniline 8-Methoxypsoralen Ochratoxin A Hydrochlorothiazide 395 393 392 391 390 Probenecid Sodium Fluoride Chlorinated Water and ...
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TR-278: 2,6-Xylidine (2,6-Dimethylaniline) (CASRN 87-62-7) in... 9.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr278.pdf
... Roxarsonu a-Methyldopa Sesquihydrate Pentachlorophenol Tribromomethane 2,4-Dichlorophenol Furosemide Hydrochlorothiazide OchratoxinA 8-Methoxypsoralen Hexachloroethane These NTP ...
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TR-373: Succinic Anhydride (CASRN 108-30-5) in F344/N Rats and... 21.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr373.pdf
... Sesquihydrate Pentachlorophenol Tribromomethane 2,4-Dichlorophenol Furosemide Hydrochlorothiazide Ochratoxin A 8-Methoxypsoralen Hexachloroethane These NTP Technical Reports are ...
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TR-399: Titanocene Dichloride (CASRN 1271-19-8) in F344/N Rats... 8.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr399.pdf
... Dimethoxane Diphenhydramine Hydrochloride Furosemide Hydrochlorothiazide Ochratoxin A 8-Methoxypmralen N,N-Dimethylaniline Hexachloroethane 4-Vinyl-1-Cyclohexene Diepoxide TR No. ...
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TR-413: Ethylene Glycol (CASRN 107-21-1) in B6C3F1Mice (Feed... 11.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr413.pdf
... Hydrochloride 394 Acetaminophen 356 Furosemide 395 Probenecid 357 Hydrochlorothiazide 396 Monochloroacetic Acid 358 Ochratoxin A 397 C.I. Direct Blue 15 359 ...
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TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB
https://ntp.niehs.nih.gov/go/tr518
... 4 Hexachlorocyclopentadiene Hexachloroethane 2,4-Hexadienal 4-Hexylresorcinol Hydrochlorothiazide Hydroquinone 8-Hydroxyquinoline Indium Phosphide Iodinated Glycerol Isobutene ...
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TR-387: dl-Amphetamine Sulfate (CASRN 60-13-9) in F344/N Rats... 10.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr387.pdf
... Furosemide 379 380 2-Chloroacetophenone Epinephrine Hydrochloride 357 358 Hydrochlorothiazide Ochratoxin A 381 382 d-Carvone Furfural 35 9 360 8-Methoxypsoralen ...
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TR-368: Nalidixic Acid (CASRN 389-08-2) in F344/N Rats and B6C3F1Mice... 13.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr368.pdf
... Roxarsone a-Methyldopa Sesquihydrate Pentachlorophenol Tribromomethane 2,4-Dichlorophenol Furosemide Hydrochlorothiazide Ochratoxin A 8-Methoxypsoralen Hexachloroethane These NTP ...
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TR-400: 2,3-Dibromo-1-Propanol (CASRN 96-13-9) in F344/N Rats... 11.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr400.pdf
... 355 Diphenhydramine Hydrochloride 402 Furan 356 Furosemide 403 Resorcinol 357 Hydrochlorothiazide 404 5,S-Diphenylhydantoin 358 Ochratoxin A 405 C.I.AcidRed114 359 ...
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TR-385: Methyl Bromide (CASRN 74-83-9) in B6C3F1Mice (Inhalation... 7.3MB
https://ntp.niehs.nih.gov/go/tr385
... Furfural 355 356 357 358 359 360 361 Diphenhydramine Hydrochloride Furosemide Hydrochlorothiazide Ochratoxin A 8-Methoxypsoralen N,N-Dimethylaniline Hexachloroethane 386 387 389 ...
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TR-388: Ethylene Thiourea (CASRN 96-45-7) in F344 Rats and B6C3F1Mice... 13.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr388.pdf
... Hydrochloride Furosemide 386 387 Tetranitromethane Amphetamine Sulfate 357 358 Hydrochlorothiazide Ochratoxin A 3 8 9 390 Sodium Azide 3,3' -Dimethylbenzidine Dihydmchloride 359 ...
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TR-390: 3,3'-Dimethylbenzidine Dihydrochloride (CASRN 612-82... 12.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr390.pdf
... 379 2-Chloroacetophenone 356 Furosemide 380 Epinephrine Hydrochloride 357 Hydrochlorothiazide 381 d-Carvone 358 Ochratoxin A 382 Furfural 359 8-Methoxypsoralen 386 ...
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TR-391: Tris(2-chloroethyl) Phosphate (CASRN 115-96-8) in F344... 11.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr391.pdf
... 380 379 Epinephrine Hydrochloride 2-Chloroacetophenone 358 357 Ochratoxin A Hydrochlorothiazide 382 3 8 1 Furfural d-Cawone 360 359 N,N-Dimethylaniline 8-Methoxypsoralen 393 ...
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TR-395: Probenecid (CASRN 57-66-9) in F344/N Rats and B6C3F1Mice... 16.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr395.pdf
... Hydrochloride 380 Epinephrine Hydrochloride 356 Furosemide 381 d-Carvone 357 Hydrochlorothiazide 382 Furfural 358 Ochratoxin A 386 Tetranitromethane 359 8-Methoxypsoralen 387 ...
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TR-397: C.I. Direct Blue 15 (CASRN 2429-74-5) in F344 Rats (Drinking... 13.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr397.pdf
... Anhydride 3,3'-Dimethoxybenzidine Dihydrochhide 358 357 356 355 Ochratoxin A Hydrochlorothiazide Furosemide Diphenhydramine Hydrochloride 393 392 391 390 Sodium Fluoride ...
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TR-401: 2,4-Diaminophenol Dihydrochloride (CASRN 137-09-7) in... 12.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr401.pdf
... 359 358 357 Hexachloroethane N,N-Dimethylaniline 8-Methoqpaoralen Ochratoxin A Hydrochlorothiazide 395 393 392 391 3 9 0 Probenecid Sodium Fluoride Chlorinated Water and ...
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TR-405: C.I. Acid Red 114 (CASRN 6459-94-5) in F344/N Rats (Drinking... 12.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr405.pdf
... 354 Dimethoxane 355 Diphenhydramine Hydrochloride 356 Furosemide 357 Hydrochlorothiazide 358 Ochratoxin A 359 8-Methcorypsoralen 360 N,N-Dimethylaniline 361 ...
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TR-408: Mercuric Chloride (CASRN 7487-94-7) in F344 Rats and... 12.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr408.pdf
... 2,4-Dichlorophenol Dimethoxane Diphenhydramine Hydrochloride Furosemide Hydrochlorothiazide Ochratoxin A 8-Methaxypsoralen N,N-Dimethylaniline Hexachloroethane ...
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TR-479: Coconut Oil Acid Diethanolamine Condensate (CASRN 68603... 7.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr479.pdf
... Red 3 HC Yellow 4 Hexachlorocyclopentadiene Hexachloroethane 4-Hexylresorcinol Hydrochlorothiazide Hydroquinone 8-Hydroxyquinoline Iodinated Glycerol Isobutene Isobutyl Nitrite ...
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TR-502: Chloral Hydrate (CASRN 302-17-0) in B6C3F1Mice (Gavage... 8.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr502.pdf
... Red 3 HC Yellow 4 Hexachlorocyclopentadiene Hexachloroethane 4-Hexylresorcinol Hydrochlorothiazide Hydroquinone 8-Hydroxyquinoline Indium Phosphide Iodinated Glycerol Isobutene ...
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TR-426: Corn Oil, Safflower Oil, and Tricaprylin (CASRNs. 8001... 18.8MB
https://ntp.niehs.nih.gov/go/tr426
... Hydrochloride 405 C.I. Acid Red 114 356 406 y-Butyrolactone Furosemide 357 Hydrochlorothiazide 407 C.I. Pigment Red 3 358 Ochratoxin A \PO8 Mercuric Chloride 359 409 Quercetin ...
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TR-394: Acetaminophen (CASRN 103-90-2) in F344 Rats and B6C3F1Mice... 14.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr394.pdf
... Hydrochloride 393 Sodium Fluoride 356 Furosemide 395 Probenecid 357 Hydrochlorothiazide 3% Monochloroacetic Acid 358 Ochratoxin A 397 C.I. Direct Blue 15 359 ...
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TR-398: Polybrominated Biphenyls (CASRN 67774-32-7)(Firemaster... 14.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr398.pdf
... 397 C.I. Direct Blue 15 356 Furmemide 399 Titanocene Dichloride 357 Hydrochlorothiazide 401 2,4-Diaminophenol Dihydrochloride 358 Ochratoxin A 402 Furan 359 ...
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TR-402: Furan (CASRN 110-00-9) in F344 Rats and B6C3F1 Mice(Gavage... 31.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr402.pdf
... Water and Chloraminated Water 356 Furosemide 393 Sodium Fluoride 357 Hydrochlorothiazide 395 Probenecid 358 Ochratoxin A 396 Monochloroacetic Acid 359 8-Methoxypsoralen ...
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TR-403: Resorcinol (CASRN 108-46-3) in F344 Rats and B6C3F1Mice... 15.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr403.pdf
... Azide 356 Furosemide 390 I o . ° 3,3 -D~methylbenztdtne Dihydrochloride 357 Hydrochlorothiazide 391 Tris(2-chloroethyl) Phosphate 358 Ochratoxin A 392 Chlorinated Water and ...
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TR-404: 5,5-Diphenylhydantoin (CASRN 57-41-0) (Phenytoin) in... 16.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr404.pdf
... 355 Diphenhydramine Hydrochloride 402 Furan 356 Furosemide 403 Resorcinol 357 Hydrochlorothiazide 405 C.I. Acid Red 114 358 Ochratoxin A 406 y-Butyrolactone 359 8-Methoxypsoralen ...
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TR-407: C.I. Pigment Red 3 (CASRN 2425-85-6) in F344/N Rats and... 15.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr407.pdf
... 357 356 355 Hexachloroethane N,N-Dimethylaniline 8-Methoxypsoralen Ochratoxin A Hydrochlorothiazide Furosemide Diphenhydramine Hydrochloride 395 393 391 390 389 387 386 Probenecid ...
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TR-411: C.I. Pigment Red 23 (CASRN 6471-49-4) in F344 Rats and... 15.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr411.pdf
... Dihydmchloride Sodium Azide Ethylene Thiourea 358 357 Ochratoxin A Hydrochlorothiazide 3% 395 Monochloroacetic Acid Probenecid 361 360 359 Hexachloroethane ...
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TR-421: Talc (CASRN 14807-96-6)(Non-Asbestiform) in F344/N Rats... 16.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr421.pdf
... 2,4-Dichlorophenol Dimethoxane Diphenhydramine Hydrochloride Furosemide Hydrochlorothiazide <9chmtoodnA S-Metharrgrpsonlen N,N-Dimethylaniline Hexachlonxthane ...
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TR-424: o-Benzyl-p-Chlorophenol (CASRN 120-32-1) in F344/N Rats... 15.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr424.pdf
... Hydrochloride 403 Resorcinol 356 Furosemide 4041 5,5-Diphenylhydantoin 357 Hydrochlorothiazide 405 C.I. Acid Red 114 358 Ochratoxin A 405 p.-Butyrolactone 359 ...
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TR-427: Turmeric Oleoresin (CASRN 8024-37-1) (Major Component... 16.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr427.pdf
... 397 C.I. Direct Blue 15 356 Furosemide 399 T i t a n e n e Dichloride 357 Hydrochlorothiazide 401 2,4-Diaminophenol Dihydrochloride 358 Ochratoxin A 402 Furan 359 ...
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TR-429: Diethylphthalate (CASRN 84-66-2) in F344/N Rats and B6C3F1Mice... 12.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr429.pdf
... Hydrochloride 407 C.I. Pigment Red 3 Furosemide 408 Mercuric Chloride Hydrochlorothiazide 409 Quercetin Ochratoxin A 410 Naphthalene 8-Methoxypsoralen 411 C.I. Pigment ...
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TR-430: C.I. Direct Blue 218 (CASRN 28407-37-6) in F344/N Rats... 16.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr430.pdf
... 354 Dimethmne 355 Diphenhydramine Hydrochloride 356 Furosemide 357 Hydrochlorothiazide 358 Ochratoxin A 359 8-Methoxypsoralen 360 N,N-Dimethylaniline 3 6 1 ...