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2018 Annual Report 6.4MB
https://ntp.niehs.nih.gov/annualreport/2018/2018annualreportdownloadpdf.pdf
... of NTP Study Data or Recommendations by Federal and State Health Regulatory and Research Agencies in FY 2018......of male 4G, 4G-LTE, and 5G networks for streaming video ...
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Peer Review Report: Draft NTP Technical Reports on Cell Phone... 1.0MB
https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2018/march/peerreview20180328_508.pdf
... Mottus was critical of FDA's critiques of the NTP study. Addition of 5G high-frequency ... He believes FCC is an industry-compromised Revised October 23, 2018 (affiliations ...
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Cell Phone Radio Frequency Radiation 59KB
https://ntp.niehs.nih.gov/whatwestudy/topics/cellphones/index.html
by cell phones for an NTP study because of widespread ... These were published as Technical Reports in November 2018. ... if the rollout of 5G will change or increase RFR exposure? ...
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Minutes: BSC; June 20, 2018 348KB
https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2018/june/minutes20180620_508.pdf
1) Report on March 26-28, 2018 Peer Review of NTP ... Peer Review of Core Study and Next Steps ... He said 5G does represent a jump into something totally ...
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Archive 43KB
https://ntp.niehs.nih.gov/update/2020/index.html
Toxicology Program study on a compound known as oxybenzone. ... Michael Wyde, Ph.D. NTP scientist weighs in on 5G technology ... ICCVAM 2018-2019 Biennial Report and ICE Version 3.1 now ...
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TR-595: Sprague Dawley (Hsd:Sprague Dawley SD) Rats Exposed to... 5.6MB
https://ntp.niehs.nih.gov/go/tr595
PhoNes NTP TR 595 NOVEMBER 2018 NTP Technical Report on the ... xix Twenty-eight-day Study......and not yet deployed, termed 5G, will utilize higher ...
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TR-596: B6C3F1/N Mice Exposed to Whole-body Radio Frequency Radiation... 4.3MB
https://ntp.niehs.nih.gov/go/tr596
PhoNes NTP TR 596 NOVEMBER 2018 NTP Technical Report on the ... xvi Twenty-eight-day Study......and not yet deployed, termed 5G, will utilize higher ...
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Peer Review Report: Draft NTP Research Report on the CLARITY... 557KB
https://ntp.niehs.nih.gov/ntp/about_ntp/rrprp/2018/april/peerreview_20180426_508.pdf
National Toxicology Program Peer Review of the Draft NTP Research Report on the CLARITY-BPA Core Study April 26, 2018 National Institute of Environmental Health Sciences Research ...
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Performance of the OptiSafe Ocular Irritation Assay in a Three... 881KB
https://ntp.niehs.nih.gov/iccvam/meetings/sot18/choksi-poster-txt-508.pdf
Study March 2018 NICEATM Poster: SOT 2018 Annual Meeting Performance of the OptiSafe Ocular Irritation Assay in a Three-Laboratory Validation Study N Choksi 1 , A Daniel 1 , S ...
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RR-09: The CLARITY-BPA Core Study: A Perinatal and Chronic Extended... 5.1MB
https://ntp.niehs.nih.gov/go/rr09
The cLaRITY-BPa coRe sTudY: a PeRINaTaL aNd chRoNIc exTeNded-dose- RaNge sTudY of BIsPheNoL a IN RaTs NTP RR 9 SEPTEMBER 2018 NTP Research Report on the CLARITY-BPA Core Study: A ...
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Minutes: BSC; Dec. 12, 2018 441KB
https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2018/december/minutesbsc20181212_508.pdf
... Bucher discussed the peer review meeting that took place at NIEHS on April 26, 2018, and the NTP Research Report that was released in September 2018. He related the Core Study ...
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Performance of the OptiSafe Ocular Irritation Assay in a Three... 1.5MB
https://ntp.niehs.nih.gov/iccvam/meetings/sot18/choksi-poster.pdf
Performance of the OptiSafe Ocular Irritation Assay in a Three-Laboratory Validation Study ... NICEATM coordinated a three-laboratory validation study of OptiSafe (Table 1) in order to: ...
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Peer Review of the Draft NTP Research Report on CLARITY-BPA Core... 21KB
https://ntp.niehs.nih.gov/events/past/2010s/2018/panel_2018-04-26.html
9221 April 26, 2018 Peer Review of the Draft NTP Research Report on CLARITY-BPA Core Study Videos There are no videos available for this meeting. Materials Final Documents Agenda ...
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Performance of the OptiSafe Ocular Irritation Assay in a Three... 21KB
https://ntp.niehs.nih.gov/iccvam/meetings/sot18/choksi-508.pdf
October 2017 NICEATM Abstract: SOT 2018 Annual Meeting Performance of the OptiSafe Ocular Irritation Assay in a Three-Laboratory Validation Study N Choksi 1 , A Daniel 1 , S Lebrun ...
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RR-08: In Vivo Repeat Dose Biological Potency Study of Triphenyl... 1.5MB
https://ntp.niehs.nih.gov/go/rr08
sPRague Dawley sD) (gaVage sTuDIes) NTP RR 8 DECEMBER 2018 NTP Research Report on In Vivo Repeat Dose Biological Potency Study of Triphenyl Phosphate (CAS No. 115-86-6) in Male ...
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Assay Application 75KB
https://ntp.niehs.nih.gov/iccvamreport/2019/confidence/assay/index.html
Methods evaluated during 2018 and 2019 addressed endpoints including inhalation toxicity, ... Electrophilic Allergen Screening Assay Validation Study Binding of a chemical to skin ...
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EPA Case Study: Evaluation of a Proposed Approach to Refine the... 1.2MB
https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2019/september/bcgnd-1-epa_case_study.pdf
of Contact Toxicity: A Case Study Using a New Approach Methodology (NAM) EPA's Office of Chemical Safety and Pollution Prevention August 30, 2018 Page 1 of 33 Table of Contents ...
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OptiSafe Validation Study 20KB
https://ntp.niehs.nih.gov/iccvamreport/2019/confidence/assay/optisafe/index.html
In this method, a test substance is applied to a semi-permeable membrane to assess the substance's potential to cause eye irritation. The study was completed in 2018 and a report ...
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OptiSafe Validation Study 22KB
https://ntp.niehs.nih.gov/iccvamreport/2021/confidence/assay/02-iccvam-optisafe/index.html
In this method, a test substance is applied to a semi-permeable membrane to assess the substance's potential to cause eye irritation. The study was completed in 2018 and a report ...
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ICCVAM Biennial Progress Report 2018-2019 (text version) 1.0MB
https://ntp.niehs.nih.gov/iccvam/docs/annrpt/iccvam-rpt-2018-2019.pdf
... criteria for waiving some types of animal study requirements. . EPA strategic plan for the Toxic Substances Control Act. In 2018, EPA released a plan for that describes how the ...
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Review and Comment on the Genomic Allergen Rapid Detection Assay 21KB
https://ntp.niehs.nih.gov/iccvamreport/2019/confidence/assay/gard/index.html
The review of the validation study report started in February 2018. The ICCVAM workgroup did not support a further comprehensive assessment and peer review of this method, based on ...
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Assay Application 106KB
https://ntp.niehs.nih.gov/iccvamreport/2021/confidence/assay/index.html
In this method, a test substance is applied to a semi-permeable membrane to assess the substance's potential to cause eye irritation. The study was completed in 2018 and a report ...
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Monograph: Night Shift Work and Light at Night; Appendix E: Shiftwork... 422KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/october/landraftmonograph_appe.pdf
... Poor sensitivity of exposure status due to lack of level, duration, or range of exposure. Adequately long follow-up duration. Papantoniou et al. 2018 +++ ⬌ The study has an ...
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Literature Search Results: Systematic Review of Fluoride Exposure... 768KB
https://ntp.niehs.nih.gov/ntp/ohat/fluoride/literature_results20200916_508.pdf
... Southeast Asian J Trop Med Public Health 41: 1200-1208. Rathore S, Meena C, Gonmei Z, Dwivedi S, Toteja GS, Bala K. 2018. Study of excess fluoride ingestion and thyroid hormone ...
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Comment: Meat-related exposures, Shalene McNeill, The Beef Checkoff... 57KB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/mcneill20180911-1.pdf
Since our earlier comment, a new study (Kruger and Zhou 2018; see attached) has been published which reviews the mechanistic evidence for heme iron from red and processed meat and ...
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CLARITY-BPA Program 42KB
https://ntp.niehs.nih.gov/whatwestudy/topics/bpa/index.html
... CLARITY-BPA Releases Grantee Data and Core Study Report Environmental Factor, October 2018 Expert Panel Reviews CLARITY-BPA Core Study Environmental Factor, May 2018 BPA Grantees ...
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Developmental Neurotoxicity (DNT) Health Effect Innovation (HEI... 2.2MB
https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2019/june/presentations/14sills_bsc_508.pdf
... Created guidance and reproductive studies document for DNT studies 2003-2011 2012 2013 2014 2015 2016 2017 2018 DNT Study Design- Continuous Exposures GD 6 GD 21 Wean PND 28 ...
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Public Health Impact 824KB
https://ntp.niehs.nih.gov/media/impact/index.html
... National Toxicology Program (NTP). 2018. NTP Research Report on the CLARITY-BPA Core Study: A Perinatal and Chronic Extended-Dose-Range Study of Bisphenol A in Rats. NTP RR 9. ...
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NTP Cancer Hazard Report: Night Shift Work and Light at Night... 10.1MB
https://ntp.niehs.nih.gov/ntp/results/pubs/cancer_assessment/lanfinal20210400_508.pdf
... A population-based case-control study (Wendeu-Foyet et al. 2018) found increased prostate-cancer risk with extensive permanent night shift work. Findings from three studies that ...
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Blood Vessel - Thrombus - Gallery - Nonneoplastic Lesion Atlas 174KB
https://ntp.niehs.nih.gov/nnl/cardiovascular/blood_vessel/thrombus/gallery/index.htm
Image of thrombus in the blood vessel from a female F344/N rat in a subchronic study Lung, Artery - Thrombus in a female F344/N rat from a subchronic study. There is an aggregate ...
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NTP Annual Report - Appendix I NTP Publications: 2019 239KB
https://ntp.niehs.nih.gov/go/2019AR_Appendix1_Publications
... Research Report 10. https://doi.org/10.22427/NTP-RR-10 National Toxicology Program (NTP). 2018. NTP research report on in vivo repeat dose biological potency study of triphenyl ...
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Monograph: Night Shift Work and Light at Night; Appendix C: Transmerid... 1.1MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/october/landraftmonograph_appc.pdf
... Window of exposure variable for each woman. Garcia-Saenz et al. 2018 ++ ⬌ The study has an adequate number of exposed subjects in the third tertile (N = 126 for visual light; N ...
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NICEATM and ICCVAM Publications, 2018-2019 76KB
https://ntp.niehs.nih.gov/iccvamreport/2019/reference/publications/index.html
... multi-laboratory study. Toxicol In Vitro 60:212-228. https://doi.org/10.1016/j.tiv.2019.05.019. Borrel A, Kleinstreuer NC, Fourches D. 2018. Exploring drug space with ChemMaps.com. ...
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Monograph: Systematic Review of Long-Term Neurological Effects... 12.7MB
https://ntp.niehs.nih.gov/ntp/ohat/sarin/sarin_draft20181219_508.pdf
NERVE AGENT SARIN Revised December 19, 2018 Office of Health Assessment and ......... 8 Study Selection ......
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Monograph: Night Shift Work and Light at Night; Appendix D: Shiftwork... 605KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/october/landraftmonograph_appd.pdf
... Study used a parsimonious "base" model to increase statistical power. Wendeu-Foyet et al. 2018 Prostate: +++ ⬌ The study measured all releveant potential confounders and used ...
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Journal Articles 39KB
https://ntp.niehs.nih.gov/iccvamreport/2019/reference/publications/articles/index.html
multi-laboratory study. Toxicol In Vitro 60:212-228. https://doi.org/10.1016/j.tiv.2019.05.019. Borrel A, Kleinstreuer NC, Fourches D. 2018. Exploring drug space with ChemMaps.com. ...
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Articles by Topic and Agency 384KB
https://ntp.niehs.nih.gov/iccvamreport/2019/tags/index.html
... In this method, a test substance is applied to a semi-permeable membrane to assess the substance's potential to cause eye irritation. The study was completed in 2018 and a report ...
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Liver - Atrophy - Nonneoplastic Lesion Atlas 180KB
https://ntp.niehs.nih.gov/nnl/hepatobiliary/liver/atrophy/index.htm
in a subchronic study Normal liver in a control female F344/N rat from a subchronic study. ... Angiectasis Liver, Bile Duct - Cyst Back to top Web page last updated on: October 12, 2018
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2017 Annual Report (PDF) 6.1MB
https://ntp.niehs.nih.gov/annualreport/2017/2017annualreportdownloadpdf.pdf
Park, NC: National Toxicology Program; 2018. Available from https://ntp.niehs.nih.gov/... Among these is the first study to investigate occupational exposure to bisphenol A by ...
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Monograph: Night Shift Work and Light at Night; August 24, 2018 6.2MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/october/landraftmonograph20180824.pdf
... homes and on outside light visible in the interior (Miller and Kinzey 2018). The results of this study are presented in Table 1-2, with median values as well as minimum and ...
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Electrophilic Allergen Screening Assay Validation Study 23KB
https://ntp.niehs.nih.gov/iccvamreport/2021/confidence/assay/01-iccvam-easa/index.html
Five ICCVAM member agencies are participating in an ongoing validation study of the assay. Testing of 10 chemicals during 2018 showed that the method has sufficiently good ...
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RR-05: National Toxicology Program Approach to Genomic Dose-Response... 574KB
https://ntp.niehs.nih.gov/go/rr05
NaTioNal Toxicology PRogRam aPPRoach To geNomic Dose-ResPoNse moDeliNg NTP RR 5 APRIL 2018 .........9 Addressing the Study Design ......
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Other Human Cancer Studies; Suril Mehta; ROCPRP; Oct. 5, 2018 770KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/october/presentations/06mehta_rocprp_508.pdf
... midnight & 5:00 AM Wendeu-Foyet et al. 2018 France Population-based 270 hours or 3 nights/month for > 1 year . Studies vary by study design, geographic location, study type, ...
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2018 CLARITY-BPA Preliminary Agenda 184KB
https://ntp.niehs.nih.gov/ntp/about_ntp/rrprp/2018/april/agenda20180426_508.pdf
Revised April 13, 2018 1 Thursday, April 26 8:30 a.m. - approximately 4:00 p.m. (meeting ... Agenda Peer Review Meeting of Draft NTP Research Report on the CLARITY-BPA Core Study ...
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Electrophilic Allergen Screening Assay Validation Study 21KB
https://ntp.niehs.nih.gov/iccvamreport/2019/confidence/assay/easa/index.html
Four ICCVAM member agencies are participating in an ongoing validation study of the assay. Testing of 10 chemicals during 2018 showed that the method has sufficiently good ...
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Peer Review Report: Draft NTP Technical Reports on Prenatal Developmen... 242KB
https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2019/july/peerreviewtrprp20190731_508.pdf
... He indicated that NTP would consider implementing this recommendation if it could be done in a concise manner. . Dr. Watson indicated that he would incorporate the 2018 study, ...
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Blood Vessel - Thrombus - Nonneoplastic Lesion Atlas 181KB
https://ntp.niehs.nih.gov/nnl/cardiovascular/blood_vessel/thrombus/index.htm
Image of thrombus in the blood vessel from a female F344/N rat in a subchronic study Lung, ... Vessel - Proliferation, Intimal Back to top Web page last updated on: October 12, 2018
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ICCVAM Participation on EURL ECVAM Activities 257KB
https://ntp.niehs.nih.gov/iccvam/docs/icatm/iccvam-ecvam-org-chart-jan2016.pdf
Scientific and regulatory aspects . Stakeholder relevance 1. Assess Submission 2. Validation Study . Planning (Validation Project Plan) . Performing study . Preparing report ...
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Guidance on Nonclinical Studies of Microdose Radiopharmaceutical... 19KB
https://ntp.niehs.nih.gov/iccvamreport/2019/utilization/policies/fda-mdrdd/index.html
In August 2018 FDA published final guidance on "Microdose Radiopharmaceutical Diagnostic Drugs: Nonclinical Study Recommendations" that provides recommendations for nonclinical ...
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Protocol for a Scoping Review of Paraquat Dichloride Exposure... 462KB
https://ntp.niehs.nih.gov/ntp/ohat/parkinson/parkinsons_protocol_508.pdf
EXPOSURE AND PARKINSON'S DISEASE May 2018 Office of Health Assessment and ......... 9 Step 4. Study Results and Summaries ...