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Peer Review Report: Draft NTP Technical Reports on Cell Phone... 904KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2018/march/peerreview20180328_508.pdf
... Mottus was critical of FDA's critiques of the NTP study. Addition of 5G high-frequency ... He believes FCC is an industry-compromised Revised October 23, 2018 (affiliations ...
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Cell Phone Radio Frequency Radiation 95KB
https://ntp.niehs.nih.gov/whatwestudy/topics/cellphones
by cell phones for an NTP study because of widespread ... These were published as Technical Reports in November 2018. ... such as 4G/4G-LTE, or 5G (which is still not fully defined). ...
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Minutes: BSC; June 20, 2018 348KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2018/june/minutes20180620_508.pdf
1) Report on March 26-28, 2018 Peer Review of NTP ... Peer Review of Core Study and Next Steps ... He said 5G does represent a jump into something totally ...
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TR-595: Sprague Dawley (Hsd:Sprague Dawley SD) Rats Exposed to... 5.6MB
https://ntp.niehs.nih.gov/go/tr595
Report 595 November 2018 National Toxicology Program ... xix Twenty-eight-day Study......and not yet deployed, termed 5G, will utilize higher ...
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TR-596: B6C3F1/N Mice Exposed to Whole-body Radio Frequency Radiation... 4.3MB
https://ntp.niehs.nih.gov/go/tr596
Report 596 November 2018 National Toxicology Program ... xvi Twenty-eight-day Study......and not yet deployed, termed 5G, will utilize higher ...
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Peer Review Report: Draft NTP Research Report on the CLARITY... 557KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/rrprp/2018/april/peerreview_20180426_508.pdf
National Toxicology Program Peer Review of the Draft NTP Research Report on the CLARITY-BPA Core Study April 26, 2018 National Institute of Environmental Health Sciences Research ...
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RR-09: The CLARITY-BPA Core Study: A Perinatal and Chronic Extended... 5.1MB
https://ntp.niehs.nih.gov/ntp/results/pubs/rr/reports/rr09_508.pdf
The cLaRITY-BPa coRe sTudY: a PeRINaTaL aNd chRoNIc exTeNded-dose- RaNge sTudY of BIsPheNoL a IN RaTs NTP RR 9 SEPTEMBER 2018 NTP Research Report on the CLARITY-BPA Core Study: A ...
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Minutes: BSC; Dec. 12, 2018 441KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2018/december/minutesbsc20181212_508.pdf
... Bucher discussed the peer review meeting that took place at NIEHS on April 26, 2018, and the NTP Research Report that was released in September 2018. He related the Core Study ...
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RR-08: In Vivo Repeat Dose Biological Potency Study of Triphenyl... 1.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr08_508.pdf
sPRague Dawley sD) (gaVage sTuDIes) NTP RR 8 DECEMBER 2018 NTP Research Report on In Vivo Repeat Dose Biological Potency Study of Triphenyl Phosphate (CAS No. 115-86-6) in Male ...
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Documents Provided to the NTP Board of Scientific Counselors... 55.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/fluoride/documents_provided_bsc_wg_031523.pdf
... and are not included in the study totals for IQ because the main study by Yu et al. (2018) is considered a better representation of the IQ results. g Green et al. ...
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ICCVAM Biennial Progress Report 2018-2019 (text version) 1.0MB
https://ntp.niehs.nih.gov/iccvam/docs/annrpt/iccvam-rpt-2018-2019.pdf
... criteria for waiving some types of animal study requirements. . EPA strategic plan for the Toxic Substances Control Act. In 2018, EPA released a plan for that describes how the ...
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Literature Search Results: Systematic Review of Fluoride Exposure... 743KB
https://ntp.niehs.nih.gov/ntp/ohat/fluoride/literature_results20200916_508.pdf
... Southeast Asian J Trop Med Public Health 41: 1200-1208. Rathore S, Meena C, Gonmei Z, Dwivedi S, Toteja GS, Bala K. 2018. Study of excess fluoride ingestion and thyroid hormone ...
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Monograph: Night Shift Work and Light at Night; Appendix E: Shiftwork... 422KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/october/landraftmonograph_appe.pdf
... Poor sensitivity of exposure status due to lack of level, duration, or range of exposure. Adequately long follow-up duration. Papantoniou et al. 2018 +++ ⬌ The study has an ...
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NTP Cancer Hazard Report: Night Shift Work and Light at Night... 10.1MB
https://ntp.niehs.nih.gov/ntp/results/pubs/cancer_assessment/lanfinal20210400_508.pdf
... A population-based case-control study (Wendeu-Foyet et al. 2018) found increased prostate-cancer risk with extensive permanent night shift work. Findings from three studies that ...
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MFDS NAMs Report: Regulatory Acceptance and Research Outcomes 20.5MB
https://ntp.niehs.nih.gov/sites/default/files/2024-01/MFDS_NAMs_Report-2023-508.pdf
... the OECD workplan in April 2016 and adopted in the TG 429 in June 2018 following a successful validation study and an independent peer-review. ● There has been an increasing ...
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Research Reports 100KB
https://ntp.niehs.nih.gov/publications/reports/rr
The CLARITY-BPA Core Study: A Perinatal and Chronic Extended-Dose-Range Study of Bisphenol A in Rats 2018 Research Report RR-08 PDF (1.51 MB) In Vivo Repeat Dose Biological ...
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Monograph: Night Shift Work and Light at Night; Appendix C: Transmerid... 1.1MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/october/landraftmonograph_appc.pdf
... Window of exposure variable for each woman. Garcia-Saenz et al. 2018 ++ ⬌ The study has an adequate number of exposed subjects in the third tertile (N = 126 for visual light; N ...
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Monograph: Night Shift Work and Light at Night; Appendix D: Shiftwork... 605KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/october/landraftmonograph_appd.pdf
... Study used a parsimonious "base" model to increase statistical power. Wendeu-Foyet et al. 2018 Prostate: +++ ⬌ The study measured all releveant potential confounders and used ...
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NTP Monograph: State of the Science Concerning Fluoride Exposure... 18.7MB
https://ntp.niehs.nih.gov/go/mgraph08
... and are not included in the study totals for IQ because the main study by Yu et al. (2018) is considered a better representation of the IQ results. g Green et al. ...
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RR-05: National Toxicology Program Approach to Genomic Dose-Response... 559KB
https://ntp.niehs.nih.gov/ntp/results/pubs/rr/reports/rr05_508.pdf
NaTioNal Toxicology PRogRam aPPRoach To geNomic Dose-ResPoNse moDeliNg NTP RR 5 APRIL 2018 .........9 Addressing the Study Design ......
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2018 CLARITY-BPA Preliminary Agenda 184KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/rrprp/2018/april/agenda20180426_508.pdf
Revised April 13, 2018 1 Thursday, April 26 8:30 a.m. - approximately 4:00 p.m. (meeting ... Agenda Peer Review Meeting of Draft NTP Research Report on the CLARITY-BPA Core Study ...
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Monograph: Night Shift Work and Light at Night; August 24, 2018 6.2MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/october/landraftmonograph20180824.pdf
... homes and on outside light visible in the interior (Miller and Kinzey 2018). The results of this study are presented in Table 1-2, with median values as well as minimum and ...
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Peer Review Report: Draft NTP Technical Reports on Prenatal Developmen... 242KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2019/july/peerreviewtrprp20190731_508.pdf
... He indicated that NTP would consider implementing this recommendation if it could be done in a concise manner. . Dr. Watson indicated that he would incorporate the 2018 study, ...
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Panel Roster: Cell phone Peer Review Meeting 2018 218KB
https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2018/march/roster_20180328_508.pdf
March 30, 2018 Peer Review Panel 2 (provided input on study findings and voted on NTP's draft conclusions) Rick Adler, DVM, PhD, DACVP Senior Director and US Head of Discovery and ...
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Protocol: Occupational Exposure to Cancer Chemotherapy Agents... 883KB
https://ntp.niehs.nih.gov/ntp/ohat/aheaoecca/protocol201812_508.pdf
... OHAT Evaluation of Occupational Exposure to Chemotherapy and Health, Revised Dec 7, 2018 Page 10 of 61 Table 3. Inclusion and Exclusion Criteria to Determine Study Eligibility ...
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Protocol for a Scoping Review of Paraquat Dichloride Exposure... 462KB
https://ntp.niehs.nih.gov/ntp/ohat/parkinson/parkinsons_protocol_508.pdf
EXPOSURE AND PARKINSON'S DISEASE May 2018 Office of Health Assessment and ......... 9 Step 4. Study Results and Summaries ...
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Public Comment: 2022 SACATM Meeting 80KB
https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2022/cmts/sacatm_2022_validation_twbl-comments.pdf
Experimentation with acrylamide has been occurring for decades as has its industrial use. However, it was not until 2018 that an animal study investigating subchronic ...
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NTP Working Group Report: Draft State of the Science Monograph... 20.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/wgrptbsc20230400.pdf
... Repeated urinary measures during pregnancy are reported to have reasonable reproducibility over time, although in one study by Thomas et al. (2018), urinary fluoride concentrations ...
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NTP Board of Scientific Counselors Working Group Report on the... 9.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may16/bsc_wg_report_final_version_bsc_approved051623_508.pdf
... Repeated urinary measures during pregnancy are reported to have reasonable reproducibility over time, although in one study by Thomas et al. (2018), urinary fluoride concentrations ...
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NTP Working Group Report: Draft State of the Science Monograph... 9.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may16/meeting_materials/wgrptbsc20230400_interimver_508.pdf
... Repeated urinary measures during pregnancy are reported to have reasonable reproducibility over time, although in one study by Thomas et al. (2018), urinary fluoride concentrations ...
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Current State of Play: OECD Discussions on Doses Selection in... 1.9MB
https://ntp.niehs.nih.gov/iccvam/meetings/kmd-symp-2020/ppt/03-gourmelon-508.pdf
guidance. 2 WNT decision in 2018: Text added in chronic, reproductive and developmental tox studies (e.g. TG 443) Dose selection 20. Normally, the study should include at least ...
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ICCVAM Participation on EURL ECVAM Activities 257KB
https://ntp.niehs.nih.gov/iccvam/docs/icatm/iccvam-ecvam-org-chart-jan2016.pdf
Scientific and regulatory aspects . Stakeholder relevance 1. Assess Submission 2. Validation Study . Planning (Validation Project Plan) . Performing study . Preparing report ...
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Rat Oral Acute Toxicity Database and Evaluation of Variability 1.9MB
https://ntp.niehs.nih.gov/iccvam/meetings/at-models-2018/ppt/4-karmaus.pdf
Predictive Models for Acute Oral Systemic Toxicity Workshop April 11, 2018 Disclaimer: ILS ... a dataset of rate acute oral toxicity study LD50 data 2. Characterize the dataset to ...
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Peer Review Report of the EpiSensA Skin Sensitization Assay ... 25KB
https://ntp.niehs.nih.gov/iccvam/meetings/sot23/reinke-sot2023-abstract_508.pdf
Between 2018 and 2022, the EpiSensA underwent a multilaboratory validation study with the support of the Japanese Center for the Validation of Alternative Methods (JaCVAM) and an ...
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Monograph: Night Shift Work and Light at Night; Appendix B: Shiftwork... 1.6MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/october/landraftmonograph_appb.pdf
Appendix B: Shiftwork and Cancer August 24, 2018 Office of the Report on Carcinogens ... B-3: Breast cancer and shiftwork COHORT study results ......
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Combined Exposures and Mixtures Program; BSC; Feb. 2, 2021 277KB
https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2021/february/meeting_materials/cem_bsc_508.pdf
... * Xie G, Wang S, Zhang H, Zhao A, Liu J, Ma Y, Lan K, Ni Y, Liu C, Liu P et al. 2018. Poly-pharmacokinetic Study of a Multicomponent Herbal Medicine in Healthy Chinese Volunteers. ...
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Human Cancer Studies; Suril Mehta; RoC; Jan. 24, 2018 644KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/january/presentations/humancancerstudies_508.pdf
January 24, 2018 Draft RoC Monograph on Antimony Trioxide Outline Human Cancer Studies and ... Lung Cancer Occupational cohort study Study design Exposure assessment Likely antimony ...
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Study Reports 1.1MB
https://ntp.niehs.nih.gov/publications/reports
... (Han)] Rats and B6C3F1/N Mice (Inhalation Studies) 2018 Technical Report TR-592 PDF (1.95 MB) Toxicology and Carcinogenesis Study of Dietary Zinc (CASRN 5263-02-5) in Sprague ...
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CLARITY-BPA Program 74KB
https://ntp.niehs.nih.gov/whatwestudy/topics/bpa
... NTP Board of Scientific Counselor Meeting, Research Triangle Park, NC, June 2018 CLARITY-BPA Research Program: Peer Review of Core Study and Next Steps Publications Camacho L, ...
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ICCVAM Biennial Progress Report 2020-2021 940KB
https://ntp.niehs.nih.gov/sites/default/files/iccvam/docs/annrpt/iccvam-rpt-2020-2021.pdf
... In this method, a test substance is applied to a semi- permeable membrane to assess the substance's potential to cause eye irritation. The study was completed in 2018 and a report ...
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TOX-78: Triethylamine (CASRN 121-44-8) Administered by Inhalation... 2.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox078_508.pdf
.../N RaTS aNd b6c3f1/N mice NTP TOX 78 MARCH 2018 NOT FOR Review Draft NTP Technical Report ... The Toxicity Study Report series began in 1991. The studies described in the Toxicity ...
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RR-16: Scoping Review of Paraquat Dichloride Exposure and Parkinson... 2.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr16_508.pdf
... Exposure and Parkinson's Disease 6 were not limited by study design, language restrictions, or publication year. The following databases were searched most recently on May 24, 2018 ...
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Monograph: Antimony Trioxide; Appendices; Aug. 15, 2018 1.6MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/january/antimonydraftmonograph_appendices_revised.pdf
Appendices August 15, 2018 Office of the Report on ... Appendix D: Animal Study Quality Tables ... R2,FOS,GADD45A,GADD45G,GEM,HBEGF,HSPB7,IER3,IFIT ...
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Abstract for RR-06 56KB
https://ntp.niehs.nih.gov/publications/reports/rr/rr06
Report Date: June 2018 Full Report PDF Abstract Genetic variability in humans is a key ... This study was designed to evaluate baseline characteristics of J:DO mice that could serve ...
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All Past Events 916KB
https://ntp.niehs.nih.gov/events/past
... Agenda Final Documents Peer Review of the Draft NTP Research Report on CLARITY-BPA Core Study Final Documents April 26, 2018 Final Report: Clarity-BPA Meeting Materials Peer Review ...
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DART-03: Prenatal Development Studies of Vinpocetine (CASRN 42971... 1.2MB
https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart03_508.pdf
... He indicated that NTP would consider implementing this recommendation if it could be done in a concise manner. . Dr. Watson indicated that he would incorporate the 2018 study, ...
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Comment: Fluoride; George R. Shepley and Raymond A. Cohlmia;... 537KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/publiccomm/shepley-cohlmia20230428_bsc_508.pdf
... Out of ten publications, nine used a non-probability convenience sample. Only one study (Yu et al. 2018) sampled more than ten villages/towns/cities, which should decrease ...
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TOX-84: Toxicity Studies of o-Phthalaldehyde (CASRN 643-79-8... 5.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox084_508.pdf
NTP TOX 84 JANUARY 2018 NTP Technical Report on the Toxicity Studies of o-Phthalaldehyde ... The Toxicity Study Report series began in 1991. The studies described in the Toxicity ...
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DART-04: Prenatal Development Studies of Dimethylaminoethanol... 1006KB
https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart04_508.pdf
... He indicated that NTP would consider implementing this recommendation if it could be done in a concise manner. . Dr. Watson indicated that he would incorporate the 2018 study, ...
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Summary Minutes December 7-8, 2017 NTP Board of Scientific Counselors 352KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2017/december/minutes20171208_508.pdf
... on dermal irritancy and hypersensitivity study are also expected in 2018, as are several subchronic toxicity studies (TOX Technical Reports). 1) Questions for Clarification Dr. ...