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TR-388: Ethylene Thiourea (CASRN 96-45-7) in F344 Rats and B6C3F1Mice... 13.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr388.pdf
TOXICOLOGY AND CARCINOGENESIS STUDIES OF ETHYLENE THIOUREA (CAS NO. 96-45-7) IN F344/N ... TOXICOLOGY AND CARCINOGENESIS STUDIES OF ETHYLENE THIOUREA (CAS NO. 96-45-7) IN F344/N ...
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RoC Profile: Ethylene Thiourea; 15th RoC 2021 152KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/ethylenethiourea.pdf
Thiourea CAS No. 96-45-7 Reasonably anticipated to be a human carcinogen First listed in the Fourth Annual Report on Carcinogens (1985) H N N H S Carcinogenicity Ethylene thiourea ...
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RoC Profile: Thiourea; 15th RoC 2021 126KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/thiourea.pdf
Thiourea CAS No. 62-56-6 Reasonably anticipated to be a human carcinogen First listed in the Third Annual Report on Carcinogens (1983) S C H 2 N NH 2 Carcinogenicity Thiourea is ...
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TR-148: 1-Phenyl-2-thiourea (CASRN 103-85-5) 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr148.pdf
No. 148 1978 BIOASSAY OF 1-PHENYL-2-THIOUREA FOR POSSIBLE CARCINOGENICITY CAS No. ... of Health BIOASSAY OF l-PHENYL-2-THIOUREA FOR POSSIBLE CARCINOGENICITY ...
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Abstract for TR-388 72KB
https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr388
Toxicology and Carcinogenesis Studies of Ethylene Thiourea in F344/N Rats and B6C3F1 Mice ... Full Report PDF Abstract Ethylene thiourea is a white crystalline solid used extensively ...
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1-Phenyl-2-thiourea: Target Organs and Levels of Evidence for... 56KB
https://ntp.niehs.nih.gov/data/tr/100s/tr148levels
9 1-Phenyl-2-thiourea: Target Organs and Levels of Evidence for TR-148 Bioassay of 1-Phenyl-2-thiourea for Possible Carcinogenicity (CASRN 103-85-5) Chemical (Study Title) CASRN ...
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Abstract for TR-148 61KB
https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr148
Abstract for TR-148 Bioassay of 1-Phenyl-2-thiourea for Possible Carcinogenicity CASRN: ... Full Report PDF Abstract 1-Phenyl-2-thiourea was selected for bioassay by the National ...
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Target Organs and Levels of Evidence for TR-388 59KB
https://ntp.niehs.nih.gov/data/tr/300s/tr388levels
Thiourea (CASRN 96-45-7) in F344 Rats and B6C3F1 Mice (Feed Studies) Chemical (Study Title) CASRN Peer Review Date Route/Exposure Levels Study Laboratory Ethylene thiourea ...
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Abstract for TR-149 62KB
https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr149
Synonyms/Common Names: 1,3-diethyl-2-thiourea; 1,3-diethylthiourea Report Date: 1979 ... to ethylene thiourea, a tumorigen in hybrid mice (C57BL/6 x C3H/Anf and C57BL/6 x AKR). ...
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Abstract for TR-129 61KB
https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr129
...,N'-trimethylthiourea; 1,1,3-trimethyl-2-thiourea Report Date: 1979 Full Report PDF ... because it is a derivative of thiourea, a liver carcinogen in Osborne-Mendel rats. ...
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TR-149: N,N'-Diethylthiourea (CASRN 105-55-5) 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr149.pdf
... of N,N'-diethyl- thiourea was conducted using Fischer 344 rats and B6C3F1 mice. ... IN RATS TREATED WITH N,N'-DIETHYL- THIOUREA C-l APPENDIX D SUMMARY OF THE INCIDENCE ...
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Abstract for TR-132 61KB
https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr132
Abstract 2,5-Dithiobiurea, a component of photographic chemicals, was selected for bioassay by the National Cancer Institute because it is a dimer of thiourea, a liver, thyroid and ...
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Appendix G; 15th RoC 2021 73KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf
Phenacetin 62-50-0 see Ethylmethanesulfonate 62-55-5 see Thioacetamide 62-56-6 see Thiourea 62-75-9 (N-nitrosodimethylamine) see N-Nitrosamines: 15 Listings 63-92-3 see ...
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Minutes: BSC TRRS; Nov. 20, 1989 820KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1989/nov/89nov20trrsmins_508.pdf
Ethylene Thiourea 2-Chloroacetophenone(CN) I n h a l a t i o n 3 o-Chlorobenzalmalononitri... The motion was accepted by t e n yes votes t o one no vote (Carlson). Ethylene Thiourea. ...
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Vagina - Dilation - Nonneoplastic Lesion Atlas 287KB
https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/vagina/Dilation
National Toxicology Program. 1992. NTP TR-388. Toxicology and Carcinogenesis Studies of Ethylene Thiourea (CAS: 96-45-7) in F344 Rats and B6C3F1 Mice (Feed Studies). NTP, Research ...
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TR-129: Trimethylthiourea (CASRN 2489-77-2) 2.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr129.pdf
... SUMMARY FOR B6C3F1 MICE-TRIMETHYL- THIOUREA FEEDING EXPERIMENT 11 ANALYSES OF THE ... Institute because it is a derivative of thiourea, a liver carcinogen in Osborne-Mendel ...
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Minutes: BSC TRRS; April 25, 1990 596KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1990/apr/trrs25apr1990mins_508.pdf
Deferred Studies Reevaluation DL-Amphetamine S u l f a t e Ethylene Thiourea CAS No. ... Ethylene Thiourea -- Reevaluation. The NTP t o x i c o l o g y and carcinogenesis s t u d ...
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Abstract for TR-163 63KB
https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr163
Other products prepared from calcium cyanamide include urea, thiourea, and guanidine. Fusion of calcium cyanamide with sodium chloride produces calcium cyanide, which is required ...
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Vagina - Dilation 230KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/female_reproductive/vagina/dilat/vagina-dilation-pdf-508.pdf
Elsevier, Amsterdam, 667-724. 2 Vagina - Dilation References: National Toxicology Program. 1992. NTP TR-388. Toxicology and Carcinogenesis Studies of Ethylene Thiourea (CAS: ...
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Harderian gland - Necrosis - Nonneoplastic Lesion Atlas 289KB
https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/harderian-gland/Necrosis
National Toxicology Program. 1992. NTP TR-388. Toxicology and Carcinogenesis Studies of Ethylene Thiourea (CAS: 96-45-7) in F344 Rats and B6C3F1 Mice (Feed Studies). NTP, Research ...
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Adrenal Gland, Cortex - Cellular Atypia - Nonneoplastic Lesion... 292KB
https://ntp.niehs.nih.gov/atlas/nnl/endocrine-system/adrenal-gland/Cortex-CellularAtypia
National Toxicology Program. 1992. NTP TR-388. Toxicology and Carcinogenesis Studies of Ethylene Thiourea (CAS No. 96-45-7) in F344/N Rats and B6C3F1 Mice (Feed Studies). NTP, ...
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Harderian Gland - Necrosis 282KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/special_senses/harderian/necrosis/harderian-gland-necrosis_508.pdf
.../4/339.short National Toxicology Program. 1992. NTP TR-388. Toxicology and Carcinogenesis Studies of Ethylene Thiourea (CAS: 96-45-7) in F344 Rats and B6C3F 1 Mice (Feed Studies). ...
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Adrenal Gland, Cortex - Cellular Atypia 398KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/endocrine/adrenal/cxclatyp/adrenal-gland-cortex-cellular-atypia-pdf_508.pdf
... References: National Toxicology Program. 1992. NTP TR-388. Toxicology and Carcinogenesis Studies of Ethylene Thiourea (CAS No. 96-45-7) in F344/N Rats and B6C3F1 Mice (Feed ...
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Lacrimal gland - Inflammation - Nonneoplastic Lesion Atlas 295KB
https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/lacrimal-gland/Inflammation
... National Toxicology Program. 1992. NTP TR-388. Toxicology and Carcinogenesis Studies of Ethylene Thiourea (CAS: 96-45-7) in F344 Rats and B6C3F1 Mice (Feed Studies). NTP, Research ...
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Listed Substances; 15th RoC 2021 76KB
https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf
... Epichlorohydrin Ethylene Thiourea Ethyl Methanesulfonate Furan Glass Wool ... Thioacetamide 4,4'-Thiodianiline Thiourea Toluene Diisocyanates Toxaphene ...
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Lacrimal Gland - Inflammation 441KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/special_senses/lacrimal/inflamm/lacrimal-gland-inflammation_508.pdf
.../go/6965 National Toxicology Program. 1992. NTP TR-388. Toxicology and Carcinogenesis Studies of Ethylene Thiourea (CAS: 96-45-7) in F344 Rats and B6C3F 1 Mice (Feed Studies). ...
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TR-132: 2,5-Dithiobiurea (CASRN 142-46-1) 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr132.pdf
... Institute because it is a dimer of thiourea, a liver, thyroid and Zymbal's gland ... have been given special attention because of the relationship of the compound to thiourea. ...
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TR-183: Dibutyltin Diacetate (CASRN 1067-33-0) 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr183.pdf
... receiving diets containing* l-phenyl-2-thiourea (103-85-5); amitrole (61-82-5); zinc ... hydro- chloride (2198-59-6); l-phenyl-2-thiourea (103-85-5); trimethyl- thiourea ...
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TR-398: Polybrominated Biphenyls (CASRN 67774-32-7)(Firemaster... 14.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr398.pdf
... Three chemicals, ethylene thiourea (ETU), 5,5'-diphenylhydantoin (phenytoin), and poly- ... Perinatal Toxicology and Carcinogenesis Studies of Ethylene Thiourea (CAS No. 96-45-7) in ...
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TR-056: N,N'-Dicyclohexylthiourea (CASRN 1212-29-9) 3.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr056.pdf
... Thiourea titration indicated 99.0 + 0.5% purity. Both thin-layer and high-pressure liquid ... administration of Ν, Ν'-dicyclohexyl thiourea in both Fischer 344 rats and B6C3F1 mice. ...
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15th RoC: Appendix F 174KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf
... ETS see Tobacco-Related Exposures, Environmental Tobacco Smoke ETU see Ethylene Thiourea ... ethylenethiourea see Ethylene Thiourea 1-ethyl-1-nitrosourea see ...
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TR-404: 5,5-Diphenylhydantoin (CASRN 57-41-0) (Phenytoin) in... 16.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr404.pdf
... Three chemicals, ethylene thiourea, 5,5-diphenylhydantoin (phenytoin), andpolybrominated ... 5,5-Diphenylhydantoin 0/50 0/50 Ethylene thiourea 0/50 0150 Polybrominated biphenyls ...
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ICCVAM Test Method Evaluation Report: In Vitro Test Methods for... 42.0MB
https://ntp.niehs.nih.gov/iccvam/docs/ocutox_docs/invitro-2010/tmer-vol1.pdf
... Class Thiadiazole alkyl derivative - Lubricant additive; Petrochemical product Thiourea 62-56-6 Organic sulfur compound Photographic agent; Flame- retardant; Chelation reagent ...
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Curating Chemical Use Categories and Exposure Predictions to... 1.7MB
https://ntp.niehs.nih.gov/sites/default/files/2024-03/SOT2024-Hull-poster.pdf
... Organosulfur compounds Thioethers 1 Thioureas 1 Phenylpropanoids and polyketides Cinnamic acids and derivatives 1 Depsides and depsidones 1 Filler Solubility enhancer Viscosity ...
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TR-046: Ethionamide (CASRN 536-33-4) 2.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr046.pdf
... Inc., New York, N.Y. The purity of the batch used in the chronic studies (Lot No. 24) was determined to be 98.9 + 1.2% by thiourea titration at Midwest Research Institute. ...
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TR-163: Calcium Cyanamide (CASRN 156-62-7) 3.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr163.pdf
... Other products prepared from calcium cyana- mide include urea, thiourea, and guanidine. Fusion of calcium cyanamide with sodium chloride produces calcium cyanide, which is required ...
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Appendices A-G; 15th RoC 2021 448KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf
... ETS see Tobacco-Related Exposures, Environmental Tobacco Smoke ETU see Ethylene Thiourea ... ethylenethiourea see Ethylene Thiourea 1-ethyl-1-nitrosourea see ...
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Minutes: BSC; March 13, 1990 1.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1990/march/19900313-14bsc_minutes_508be.pdf
... 3,3'-dimethylbenzidine dihydrochlor1de, ethylene thiourea, sodium azide, and tris(2-chloroethyl) phosphate, and on April 26 to review the Report of the studies on sodium fluoride. ...
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TR-181: Michler's Ketone (CASRN 90-94-8) 3.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr181.pdf
... (106-47-8); trimethyl- thiourea (2489-77-2); and p-nitrosodiphenylamine (156-10-5). ... hydrochloride (2198-59-6); l-phenyl-2-thiourea (103-85-5); trimethylthiourea ...
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TR-189: p-Chloroaniline (CASRN 106-47-8) 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr189.pdf
... ketone (90-94-8); trimethyl- thiourea (2489-77-2); and p-nitrosodiphenylamine (156-10-5). ... (95-74-9); 1-phenyl-2-thiourea (103-85-5); dibuty1tin diacetate ...
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Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf
... 14.69 Acetonitrile 75-056-8 13.72 15.38 Sodium chloride 7647-14-5 7.74 3.66 Thiourea 62-56-6 6.41 5.49 2-Butoxyethanol 111-76-2 5.43 8.73 Nicotinamide 98-92-0 5.36 5.78 ...
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Nomination Background: 1-Butyl-3-methylimidazolium chloride ... 1.5MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/ionic_liquids_508.pdf
... [(NH 2 ) 3 C + and derivatives] 4. isouroniums and thioisouroniums [urea and thiourea derivatives of general formula (NH 2 ) 2 (RX)C + where X = O or S and R = alkyl] 5. ...
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TR-145: 3-Chloro-p-Toluidine (CASRN 95-74-9) 2.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr145.pdf
... (106-47-8); 4,4'-methyl- enebis(N,N-dimethyl)-benzenamine (101-61-1); l-phenyl-2-thiourea (103-85-5); trimethylthiourea (2489-77-2); dibutyltin diacetate (1067-33-0); ...
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TR-179: p-Quinone Dioxime (CASRN 105-11-3) 3.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr179.pdf
... hydro- chloride (2198-59-6); l-phenyl-2-thiourea (103-85-5); 2-nitro-p- phenylenediamine (5307-14-2); dibutyltin diacetate (1067-33-0); and 3-chloro-p-toluidine (95-74-9). ...
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TR-184: Nitrofen (CASRN 1836-75-5) 4.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr184.pdf
...tro-p-phenylenediamine (5307-14-2); ami- trole (61-82-5); l-phenyl-2-thiourea (103-85-5); dibutyltin diacetate (1067-33-0); copper acetate (4180-12-5); and zinc acetate (557-34-6). ...
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TR-187: 5-Chloro-o-toluidine (CASRN 95-79-4) 2.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr187.pdf
... hydrochloride (2198-59-6); l-phenyl-2- thiourea (103-85-5); trimethylthiourea (2489-77-2); dibutyltin dia- cetate (1067-33-0); and 2-nitro-p-phenylenediamine (5307-14-2). ...
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Minutes: BSC; March 14, 1983 2.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1983/march/bsc_mins19830314_508.pdf
... A positive control , sodium s e l e n i t e , and a negative control, ethylene thiourea, were tested in each laboratory, and assays were run ' b l i n d ' . When a s c a t t e r ...
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TR-186: 4,4'-Methylenebis-(N,N-dimethyl)benzeneamine (CASRN 101... 5.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr186.pdf
... hydrochloride (2198-59-6); l-phenyl-2-thiourea (103-85-5); trimethylthiourea (2489-77-2); dibutyltin diacetate (1067-33-0); and 3-chloro-p-tol- uidine (95-74-9). ...
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TR-169: 2-Nitro-p-phenylenediamine (CASRN 5307-14-2) 3.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr169.pdf
... hydrochlo- ride (2198-59-6); l-phenyl-2-thiourea (103-85-5); trimethylthiourea (2489-77-2); dibutyltin diacetate (1067-33-0); and 3-chloro-p-tolui- dine (95-74-9). ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... in Species/Sex TR-388 04/25/90 Ethylene Thiourea (ETU) 96-45-7 P Clear Evidence P Clear ... N No Evidence TR-148 06/25/78 1-Phenyl-2-thiourea 103-85-5 N No Evidence N No Evidence N ...