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RoC Profile: Toluene Diisocyanates; 15th RoC 2021 156KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/toluenediisocyanates.pdf
Toluene Diisocyanates CAS No. 26471-62-5 Reasonably anticipated to be human carcinogens First listed in the Fourth Annual Report on Carcinogens (1985) Also known as TDI; ...
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Abstract for TR-372 66KB
https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr372
2abs Abstract for TR-372 Toxicology and Carcinogenesis Studies of 3,3'-Dimethoxybenzidine Dihydrochloride in F344/N Rats(Drinking Water Studies) CASRN: 20325-40-0 Chemical Formula: ...
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Minutes: BSC TRRS; Sept. 22, 1982 689KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1982/sept/82sept22trrsmin_508.pdf
d of Scientif i e Counselors N a t i onal Toxi c o l ogy Program Summary M i nutes from Reviews o f D r a f t Technical Reports o f Long-Term Carci nogenesi s B i oassays by t h e ...
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Lung - Ulceration - Nonneoplastic Lesion Atlas 290KB
https://ntp.niehs.nih.gov/atlas/nnl/respiratory-system/lung/Ulceration
Ulceration of the bronchial or bronchiolar epithelium represents loss of the lining epithelium (Figure 1 image opens in a pop-up window and Figure 2 image opens in a pop-up window ...
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RoC Profile: 4,4'-Methylenedianiline and Its Dihydrochloride... 141KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/methylenedianiline.pdf
Methylenedianiline and Its Dihydrochloride CAS Nos. 101-77-9 and 13552-44-8 Reasonably anticipated to be human carcinogens First listed in the Fourth Annual Report on Carcinogens ...
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Lung - Ulceration 269KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/respiratory/lung/ulcer/lung-ulceration-508.pdf
Ulceration Figure Legend: Figure 1 Lung, Bronchus - Ulceration in a male Wistar Han rat from an acute study. A ribbon of necrotic tissue is adjacent to the bronchial surface, which ...
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RoC Profile: 4,4'-Methylenebis(2-chloroaniline); 15th RoC 2021 143KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/methylenebis_chloroaniline.pdf
2-chloroaniline) CAS No. 101-14-4 Reasonably anticipated to be a human carcinogen First listed in the Third Annual Report on Carcinogens (1983) Also known as methylene-bis-ortho-ch...
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RoC Profile: 3,3'-Dichlorobenzidine and Its Dihydrochloride;... 146KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/dichlorobenzidine.pdf
3,3'-Dichlorobenzidine and Its Dihydrochloride CAS Nos. 91-94-1 and 612-83-9 Reasonably anticipated to be human carcinogens First listed in the Second Annual Report on Carcinogens ...
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TR-251: Commercial Grade 2,4 (80)- and 2,6 (20)- Toluene Diisocyanate... 8.9MB
https://ntp.niehs.nih.gov/go/tr251
NATIONAL TOXICOLOGY PROGRAM Technical Report Series No.251 TOXICOLOGY AND CARCINOGENESIS STUDIES OF COMMERCIAL GRADE 2,4 (80%)- AND 2,6 (20%)- TOLUENE DIISOCVANATE (CAS NO. ...
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TOX-22: N,N-Dimethylformamide (CASRN 68-12-2) 1.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox022.pdf
National Toxicology Program Toxicity Report Series Number 22 NTP Technical Report on Toxicity Studies of N,N-Dimethylformamide (CAS NO: 68-12-2) Administered by Inhalation to ...
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RoC Background Document: Chlorozotocin (CZT); Nov. 18-19, 1996 1.6MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/chlorozotocin1_508be.pdf
DOCUMENT for CHLOROZOTOCIN FINAL MARCH 1999 Prepared for the November 18-19, 1996, Meeting of the Report on Carcinogens Subcommittee of the NTP Board of Scientific Counselors ...
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TR-128: 3,3'-Dimethoxybenzidine-4,4'-diisocyanate (CASRN 91-93... 3.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr128.pdf
8 BIOASSAY OF 3,3'-DIMETHOXYBENZIDINE- 4,4'-DIISOCYANATE FOR POSSIBLE CARCINOGENICITY CAS No. 91-93-0 NCI-CG-TR-128 U.S. DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE Public Health ...
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TR-200: 2,6-Toluenediamine Dihydrochloride (CASRN 15481-70-6... 3.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr200.pdf
200 NTP No. 80-20 BIOASSAY OF 2, 6-TOLUENEDIAMINE DIHYDROCHLORIDE FOR POSSIBLE CARCINOGENICITY CAS No. 15481-70-6 NCI-CG-TR-200 NTP-80-20 U.S. DEPARTMENT OF HEALTH AND HUMAN ...
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RoC Background Document: Dyes Metabolized to 3,3'-Dimethoxybenzidine... 2.6MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/dmob_no_appendices_508.pdf
Dimethoxybenzidine Meeting of the NTP Board of Scientific Counselors Report on Carcinogens Subcommittee Prepared for the: U.S. Department of Health and Human Services Public Health ...
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GMM-10: Genetically Modified Model Report on Diispropylcarbodiimide... 380KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm10_508.pdf
STudy of diiSPRoPylcaRbodiiMide (caSRN 693-13-0) iN GeNeTically Modified (fVb TG.ac heMizyGouS) Mice aNd caRciNoGeNiciTy STudy of diiSPRoPylcaRbodiiMide iN GeNeTically Modified ...
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TR-372: 3,3'-Dimethoxybenzidine Dihydrochloride (CASRN 20325... 12.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr372.pdf
PROGRAM Technical Report Series No. 372 *..""""." ' » * ^ TOXICOLOGY AND CARCINOGENESIS STUDIES OF 3,3'-DIMETHOXYBENZIDINE DIHYDROCHLORIDE (CAS NO. 20325-40-0) IN F344/N RATS ...
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TR-248: 4,4'-Methylenedianiline Dihydrochloride (CASRN 13552... 9.5MB
https://ntp.niehs.nih.gov/go/tr248
NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 248 CARCINOGENESIS STUDIES OF 4,4-METHYLENEDIANILINE DIHYDROCHLORIDE (CAS NO. 13552-44-8) IN F344/N RATS AND B6C3Fl MICE ...
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Minutes: BSC; Dec. 13, 1996 288KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1996/december/19961213_bsc_508.pdf
AGENDA NATIONAL TOXICOLOGY PROGRAM BOARD OF SCIENTIFIC COUNSELORS December 13, 1996 Conference Center, Building 101, South Campus National Institute of Environmental Health ...
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TR-437: Hexachlorocyclopentadiene (CASRN 77-47-4) in F344/N Rats... 15.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr437.pdf
437 TOXICOLOGY AND CARCINOGENESIS STUDIES OF HEXACHLOROCYCLOPENTADIENE (CAS NO. 77-47-4) IN F344/N RATS AND B6C3Fl MICE (INHALATION STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN ...
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RoC Profile: Nitrosourea Chemotherapeutic Agents; 15th RoC 2021 215KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/nitrosoureachemotherapeuticagents.pdf
Edition For Table of Contents, see home page: http://ntp.niehs.nih.gov/go/roc Nitrosourea Chemotherapeutic Agents R 3 N C N O N R 1 O R 2 Generic nitrosourea structure ...
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GMM-09: Genetically Modified Model Report on Dicyclohexylcarbodiimide... 1.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm09_508.pdf
STudieS of dicyclohexylcaRbodiiMide (caSRN 538-75-0) iN f344/N RaTS, b6c3f1 Mice, aNd GeNeTically Modified (fVb TG.ac heMizyGouS) Mice aNd caRciNoGeNiciTy STudy of ...
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TR-523: Diisopropylcarbodiimide (CASRN 693-13-0) in F344/N Rats... 10.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr523.pdf
DIISOPROPYLCARBODIIMIDE (CAS No. 693-13-0) IN F344/N RATS AND B6C3F 1 MICE (DERMAL STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 February ...
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TR-541: Formamide (CASRN 75-12-7) in F344/N rats and B6C3F1 Mice... 2.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr541.pdf
NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF FORMAMIDE (CAS NO. 75-12-7) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. ...
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Background: Dimethylethanolamine (DMAE) [108-01-0] and Selected... 1.3MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/dmae_update_110002_508.pdf
Dimethylethanolamine (DMAE) [108-01-0] and Selected Salts and Esters DMAE Aceglutamate [3342-61-8] DMAE p-Acetamidobenzoate [281131-6] and [3635-74-3] DMAE Bitartrate [5988-51-2] ...
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RoC Background Document: Tetrafluoroethylene; March 1999 4.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/tetrafluoroethylene1.pdf
for TETRAFLUOROETHYLENE FINAL MARCH 1999 Prepared for the October 30-31, 1997, Meeting of the Report on Carcinogens Subcommittee of the NTP Board of Scientific Counselors Prepared ...
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TOX-5: Cobalt Sulfate Heptahydrate CASRN 10026-24-1 2.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox005.pdf
NTP REPORT ON THE TOXICITY STUDIES OF COBALT SULFATE HEPTAHYDRATE IN F344/N RATS AND B6C3F 1 MICE (INHALATION STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle ...
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TOX-05: Cobalt Sulfate Heptahydrate in F344/N Rats and B6C3F1... 2.7MB
https://ntp.niehs.nih.gov/sites/default/files/2023-08/tox05_508.pdf
NTP REPORT ON THE TOXICITY STUDIES OF COBALT SULFATE HEPTAHYDRATE IN F344/N RATS AND B6C3F 1 MICE (INHALATION STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle ...
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TR-376: Allyl Glycidyl Ether (CASRN 106-92-3) in Osborne-Mendel... 14.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr376.pdf
6 3- TOXICOLOGY AND CARCINOGENESIS STUDIES OF ALLYL GLYCIDYL ETHER (CAS NO. 106-92-3) IN OSBORNE-MENDEL RATS AND B6C3Fi MICE (INHALATION STUDIES) U.S. DEPARTMENTOF HEALTH AND HUMAN ...
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Public Comment: 2-Butoxyethanol (Attachment); Seth Barna; RoC... 758KB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2013/publiccomm/barna_attachmentacc_508be.pdf
Attachment 2 Page 1 of 56 Kimberly Bateman 10/1/2013 Search Descriptions for Searches Related to the Registration of Butoxyethanol CAS# 111-76-2 Searches Conducted Sept. 27 th and ...
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Minutes: BSC; July 7, 2009 399KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2009/july/minutes20090724.pdf
National Toxicology Program Board of Scientific Counselors July 23-24, 2009 National Institute of Environmental Health Sciences Research Triangle Park, NC Summary Minutes Table of ...
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TOX-19: Formic Acid (CASRN 64-18-6) 1.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox019.pdf
National Toxicology Program Toxicity Report Series Number 19 NTP Technical Report on Toxicity Studies of Formic Acid (CAS No: 64-18-6) Administered by Inhalation to F344/N Rats ...
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Minutes: BSC; July 14, 1987 1.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1987/december/19871214bsc_minutes_508be.pdf
PROGRAM BOARD OF S C I E N T I F I C COUNSELORS D e c e m b e r 14 and 15, 1987 Surmary Minutes National Toxicology Program Board o f S c i e n t i f i c Counselors Meeting ...
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TR-377: CS2 (94 o-Chlorobenzalmalononitrile, CASRN 2698-41-1... 12.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr377.pdf
7 TOXICOLOGY AND CARCINOGENESIS STUDIES OF CS2 (94% o-CHLOROBENZALMALONONITRILE, CAS NO. 2698-41-1) IN F344/N RATS AND B6C3Fi MICE (INHALATION STUDIES) U.S. DEPARTMENT OF HEALTH ...
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Final RoC Background Document for Formaldehyde 5.8MB
https://ntp.niehs.nih.gov/ntp/roc/twelfth/2009/november/formaldehyde_bd_final.pdf
Formaldehyde January 22, 2010 U.S. Department of Health and Human Services Public Health Service National Toxicology Program Research Triangle Park, NC 27709 This Page ...
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Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf
The Murine Local Lymph Node Assay: A Test Method for Assessing the Allergic Contact Dermatitis Potential of Chemicals/Compounds The Results of an Independent Peer Review Evaluation ...
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TR-375: Vinyl Toluene (Mixed Isomers) (65%meta-isomer and 32... 20.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr375.pdf
PROGRAM Technical Report Series No. 375 (1- <~ TOXICOLOGY AND CARCINOGENESIS STUDIES OF VINYL TOLUENE (MIXED ISOMERS) (65%-71% META-ISOMER AND 32%-35% PARA-ISOMER) (CAS NO. ...
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ICCVAM Test Method Evaluation Report: In Vitro Ocular Toxicity... 5.9MB
https://ntp.niehs.nih.gov/iccvam/docs/ocutox_docs/oteval/otevalrpt.pdf
ICCVAM TEST METHOD EVALUATION REPORT: IN VITRO OCULAR TOXICITY TEST METHODS FOR IDENTIFYING SEVERE IRRITANTS AND CORROSIVES ICCVAM Test Method Evaluation Report November 2006 ...
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TOX-24: 1,6-Hexanediamine Dihydrochloride (CASRN 6055-52-3) 1.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox024.pdf
National Toxicology Program Toxicity Report Series Number 24 NTP Technical Report on Toxicity Studies of 1,6-Hexanediamine Dihydrochloride (CAS No. 6055-52-3) Administered by ...
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TOX-25: Glutaraldehyde (CASRN 111-30-8) 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox025.pdf
National Toxicology Program Toxicity Report Series Number 25 NTP Technical Report on Toxicity Studies of Glutaraldehyde (CAS No. 111-30-8) Administered by Inhalation to F344/N ...
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TOX-35: Chemical Mixture of 25 Groundwater Contaminants 11.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox35.pdf
Serie s Number 3 5 NTP Technical Report on Toxicity Studies o f A Chemical Mixture o f 25 Groundwater Contaminant s Administered in Drinking Water to F344/N Rats and B6C3F1 Mice ...
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Public Health Impact 1.5MB
https://ntp.niehs.nih.gov/media/impact
... quantities: Methyl Isocyanate (624-83-9), Aluminum Thiosulfate, and 258 other ... Type: Final Rule July 12, 1989 54 FR 33426 624-83-9 1989 FDA Cosmetics; Ban on the Use of ...
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Peer Review Evaluation Report: Oral Up-and-down Procedure (NIH... 2.1MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/udpproc/udpfin01/vol_2.pdf
HTML NIH Publication No: 02-4501 The Revised Up-and-Down Procedure: A Test Method for Determining the Acute Oral Toxicity of Chemicals Results of an Independent Peer Review ...