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Search suggestions for "63-05-8".

  1. CEBS Data Related to Androstenedione (63-05-8) https://cebs.niehs.nih.gov/cebs/test_article/63-05-8


62 results found for "63-05-8".

  1. TR-560: Androstenedione (CASRN 63-05-8) in F344/N Rats and B6C3F1... 7.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr560.pdf

    ANd CARCINOGENESIS STUdIES OF ANdROSTENEdIONE (CAS NO. 63-05-8) IN F344/N RATS ANd B6C3F1 MICE (GAVAGE STUdIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, ...

  2. Abstract for TR-560 75KB

    https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr560

    Abstract for TR-560 Toxicology and Carcinogenesis Studies of Androstenedione in F344/N Rats and B6C3F1 Mice (Gavage Studies) CASRN: 63-05-8 Chemical Formula: C19H26O2 Molecular ...

  3. Target Organs and Levels of Evidence for TR-560 60KB

    https://ntp.niehs.nih.gov/data/tr/500s/tr560levels

    Target Organs and Levels of Evidence for TR-560 Toxicology and Carcinogenesis Studies of Androstenedione (CASRN 63-05-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies) Chemical ...

  4. Minutes: BSC TRRS; Feb. 25, 2009 76KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2009/feb/minutes_final0209.pdf

    ......... 2 Androstenedione ......Androstenedione Dr. Chad Blystone, NIEHS, introduced the studies on androstenedione by ...

  5. Historical Controls: Pathology Tables by Gavage/Methylcellulose... 86KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/mice_gavmethcel_path_hist09.pdf

    Southern Research Institute 059902408 12/16/02 729 50 (1) 36(687) 53.8 Androstenedione ... Southern Research Institute 059902408 12/16/02 733 50 (5) 35(690) 65.3 Androstenedione ...

  6. Historical Controls: Pathology Tables by Gavage/Methylcellulose... 84KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/rats_gavmethcel_path_hist09.pdf

    Southern Research Institute 059902407 02/03/03 729 50 (3) 21(661) 518.7 Androstenedione ... Southern Research Institute 059902407 02/03/03 729 50 (5) 38(710) 356.5 Androstenedione ...

  7. Historical Controls: Chemicals by Species/Route/Vehicle for Fischer... 206KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009_byroute.pdf

    mixture Mice Gavage Methylcellulose Androstenedione Mice Gavage Water Ginseng Mice Gavage ... Rats Gavage Methylcellulose Androstenedione Rats Gavage Water Ginseng Rats Gavage ...

  8. Historical Controls: Pathology Tables by Gavage/Methylcellulose... 135KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/gavmethylcellmice2010mar.pdf

    Southern Research Institute 059902408 12/16/02 729 50(1) 36(687) 53.8 Androstenedione ... Southern Research Institute 059902408 12/16/02 733 50(5) 35(690) 65.3 Androstenedione ...

  9. Historical Controls: Pathology Tables by Gavage/Methylcellulose... 136KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/gavmethylcellrats2010mar.pdf

    Southern Research Institute 059902407 02/03/03 729 50(3) 21(661) 518.7 Androstenedione ... Southern Research Institute 059902407 02/03/03 729 50(5) 38(710) 356.5 Androstenedione ...

  10. Nomination Background: d-Pseudoephedrine (CASRN: 90-82-4) 388KB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/ephedrinealkaloids_508.pdf

    with other performance enhancers, such as androstenedione and creatine monohydrate. ... These include chromium picolinate, androstenedione, and yohimbe bark extract. INPUT FROM ...

  11. Agenda: BSC TRRS; Feb. 25, 2009 125KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2009/feb/trrs25feb2009agenda_508.pdf

    or no toxicity data Feed, male and female F344/N rats and B6C3F1 mice Androstenedione [63-05-8] TR 560 Dietary supplement that was used by athletes during training but now is ...

  12. Historical Controls: Chemicals by Sex/Species/Route/Vehicle for... 14KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/histcont_2010_studies.pdf

    and Female Gavage Methylcellulose Androstenedione Mice B6C3F1 Male and Female Gavage ... and Female Gavage Methylcellulose Androstenedione Rats F 344/N Male and Female Gavage ...

  13. Historical Controls: Pathology Tables by Gavage/Methylcellulose... 140KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/micegavmethylcellulose.pdf

    Southern Research Institute 059902408 12/16/02 729 50(1) 36(687) 53.8 Androstenedione ... Southern Research Institute 059902408 12/16/02 733 50(5) 35(690) 65.3 Androstenedione ...

  14. Historical Controls: Pathology Tables by Gavage/Methylcellulose... 136KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/ratsgavmethylcellulose.pdf

    Southern Research Institute 059902407 02/03/03 729 50(3) 21(661) 518.7 Androstenedione ... Southern Research Institute 059902407 02/03/03 729 50(5) 38(710) 356.5 Androstenedione ...

  15. Historical Controls: Chemicals by Sex/Species/Route/Vehicle for... 83KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont_2011_studies.pdf

    and Female Gavage Methylcellulose Androstenedione Mice B6C3F1 Male and Female Gavage ... and Female Gavage Methylcellulose Androstenedione Rats F 344/N Male and Female Gavage ...

  16. Historical Controls: All Route and Vehicles for Rats; Studies... 162KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2008/r_hcrtp_allrte_20081100.pdf

    Southern Research Institute 059902407 02/03/03 729 50 (3) 21(661) 518.7 Androstenedione ... Southern Research Institute 059902407 02/03/03 729 50 (5) 38(710) 356.5 Androstenedione ...

  17. Historical Controls: Pathology Tables for All Routes/Vehicles... 176KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009-05-14-hist-miceallroutes.pdf

    Southern Research Institute 059902408 12/16/02 729 50 (1) 36(687) 53.8 Androstenedione ... Southern Research Institute 059902408 12/16/02 733 50 (5) 35(690) 65.3 Androstenedione ...

  18. Historical Controls: Pathology Tables for All Routes/Vehicles... 174KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009-05-14-hist-ratsallroutes.pdf

    Southern Research Institute 059902407 02/03/03 729 50 (3) 21(661) 518.7 Androstenedione ... Southern Research Institute 059902407 02/03/03 729 50 (5) 38(710) 356.5 Androstenedione ...

  19. Historical Controls: Pathology Tables for All Routes/Vehicles... 307KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/2010-03-22-hist-miceallroutes.pdf

    Southern Research Institute 059902408 12/16/02 729 50(1) 36(687) 53.8 Androstenedione ... Southern Research Institute 059902408 12/16/02 733 50(5) 35(690) 65.3 Androstenedione ...

  20. Historical Controls: Pathology Tables for All Routes/Vehicles... 309KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/2010-03-22-hist-ratsallroutes.pdf

    Southern Research Institute 059902407 02/03/03 729 50(3) 21(661) 518.7 Androstenedione ... Southern Research Institute 059902407 02/03/03 729 50(5) 38(710) 356.5 Androstenedione ...

  21. Historical Controls: Pathology Tables for All Routes/Vehicles... 308KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_mice_allroutes.pdf

    Southern Research Institute 059902408 12/16/02 729 50(1) 36(687) 53.8 Androstenedione ... Southern Research Institute 059902408 12/16/02 733 50(5) 35(690) 65.3 Androstenedione ...

  22. Historical Controls: Pathology Tables All Routes/Vehicles for... 309KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_rats_allroutes.pdf

    Southern Research Institute 059902407 02/03/03 729 50(3) 21(661) 518.7 Androstenedione ... Southern Research Institute 059902407 02/03/03 729 50(5) 38(710) 356.5 Androstenedione ...

  23. Addendum to ICCVAM Evaluation of In Vitro Test Methods for Detecting... 2.9MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edaddendfinal.pdf

    ... are also aromatase inhibitors (4-OH androstenedione, chrysin, and dicofol) and are also ... Available Replacement *4-OH Androstenedione Aromatase Inhibitor AROM + - +++ $53 ...

  24. Adrenal Gland, Cortex, X-Zone - Atrophy - Nonneoplastic Lesion... 298KB

    https://ntp.niehs.nih.gov/atlas/nnl/endocrine-system/adrenal-gland/CortexX-Zone-Atrophy

    ... PMD. 2011. Toxicity and carcinogenicity of androstenedione in F344/N rats and B6C3F1 mice. ... and Carcinogenesis Studies of Androstenedione (CAS No. 63-05-8) in F344/N Rats and ...

  25. Risk Assessment of Exposure to Triazole Fungicides by Human Biomonitor... 1.3MB

    https://ntp.niehs.nih.gov/sites/default/files/2024-03/SOT2024-Marciano-poster.pdf

    ... Fig. 5. Total testosterone and androstenedione. Values expressed as median and 95% ... Male volunteers § Total testosterone § Androstenedione . Male volunteers Legend Men from ...

  26. Presentation: Developing AOPs from PPAR Activation Leading to... 738KB

    https://ntp.niehs.nih.gov/iccvam/meetings/aop-wksp-2014/presentations/nepelska-508.pdf

    ... StAR TSPO cholesterol pregnenolone P450scc 3 β -HSD-III cholesterol progesterone androstenedione aromatase KE 8 KE KE AO Chemical Initiator Decreased testosterone levels ...

  27. Adrenal Gland, Cortex, X-Zone - Atrophy 412KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/endocrine/adrenal/cxzatrophy/adrenal-gland-cortex-xzone-atrophy-pdf_508.pdf

    ... PMD. 2011. Toxicity and carcinogenicity of androstenedione in F344/N rats and B6C3F1 mice. ... and Carcinogenesis Studies of Androstenedione (CAS No. 63-05-8) in F344/N Rats and ...

  28. Adrenal glands - Accessory Adrenocortical Nodule - Nonneoplastic... 299KB

    https://ntp.niehs.nih.gov/atlas/nnl/endocrine-system/adrenal-gland/AccessoryAdrenocorticalNodule

    ... National Toxicology Program. 2010. NTP TR-560. Toxicology and Carcinogenesis Studies of Androstenedione (CAS No. 63-05-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies). NTP, ...

  29. Adrenal Gland - Accessory Adrenocortical Nodule 432KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/endocrine/adrenal/acnodule/adrenal-gland-accessory-adrenocortical-nodule-pdf_508.pdf

    ... Adrenal Gland - Accessory Adrenocortical Nodule References: National Toxicology Program. 2010. NTP TR-560. Toxicology and Carcinogenesis Studies of Androstenedione (CAS No. 63-05-8...

  30. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... SE Some Evidence NE No Evidence EE Equivocal Evidence TR-560 02/25/09 Androstenedione 63-05-8 EE Equivocal Evidence EE Equivocal Evidence P Clear Evidence P Clear Evidence ...

  31. ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential... 10.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edfinalrpt0503/edfinrpt.pdf

    ... Pharmaceutical Anastrazole 120511-73-1 Nitrile; Triazole Pharmaceutical 4-Androstenedione 63-05-8 Steroid, nonphenolic Hormone Apigenin 520-36-5 Flavanoid; Flavone; Phenol ...

  32. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... Report TR-560 PDF (7.19 MB) Toxicology and Carcinogenesis Studies of Androstenedione (CASRN 63-05-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies) 2010 Technical Report TR-559 ...

  33. NICEATM Validation Study Report on the MCF-7 Cell Proliferation... 1.8MB

    https://ntp.niehs.nih.gov/iccvam/methods/endocrine/mcf7/mcf7-valstudyreport-19jun12-wcv2-draft.pdf

    ... Drug Enforcement Agency (i.e., 4-androstenedione, 5α-dihydrotestosterone, methyl ... acid NEG (1/1) NEG (1/1) NEG 3 4- Androstenedione NEG (1/1) NT NEG 3 4-Cumylphenol POS ...

  34. NTP 2014: Current Directions & Evolving Strategies 3.3MB

    https://ntp.niehs.nih.gov/ntp/pubs/currentdirections2014_508.pdf

    ... following multipurpose and miscellaneous use supplements: Aloe vera, androstenedione, bitter orange, ephedra, Ginkgo biloba, ginseng, goldenseal, kava kava, milk thistle and senna. ...

  35. RoC Profile: Estrogens, Steroidal; 15th RoC 2021 161KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/estrogenssteroidal.pdf

    ... After meno- pause, most estrogen naturally occurring in a woman's body comes from peripheral tissues that produce estrone from androstenedione, a hormone released by the adrenal ...

  36. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... Report TR-560 PDF (7.19 MB) Toxicology and Carcinogenesis Studies of Androstenedione (CASRN 63-05-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies) 2010 Technical Report TR-559 ...

  37. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... TR-560 PDF (7.19 MB) Toxicology and Carcinogenesis Studies of Androstenedione (CASRN 63-05-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies) 2010 Long-Term ...

  38. RoC Background Document: Steroidal Estrogens; Dec. 13-14, 2000 1.7MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/se_no_appendices_508be.pdf

    ... After menopause, endogenous estrogen is produced by the conversion of androstenedione ... is produced in the peripheral tissues by the conversion of androstenedione to estrone. ...

  39. Minutes: BSC; July 7, 2009 399KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2009/july/minutes20090724.pdf

    ... studies of goldenseal root powder, androstenedione, 2,3',4,4',5-pentachlorobiphenyl (PCB ... evidence of carcinogenic activity of androstenedione in male F344/N rats based on ...

  40. ICCVAM Test Method Evaluation Report on the BG1Luc ER TA Test... 17.5MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/bg1lucer-ta-tmer-combined.pdf

    ... acid 93-76-5 Carboxylic Acid Herbicide 99.3 Sigma-Aldrich Corporation 4-Androstenedione 63-05-8 Steroid Pharmaceutical 98.6 Sigma-Aldrich Corporation/ Hiyoshi- International ...

  41. Minutes: BSC; April 13, 2011 257KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2011/april/minutesbsc20110413.pdf

    ... To illustrate the outcomes of the comparisons, he showed data for tetralin in male rats and androstenedione in female rats. The proposed HC tests, he explained, offer several ...

  42. RR-04: Biological Activity of Bisphenol A (BPA) Structural Analogues... 7.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr04_508.pdf

    ... Androgen endpoints in vitro included (a) receptor binding, (b) reporter gene activity, (c) cellular proliferation, and (d) steroidogenic production of testosterone, androstenedione...

  43. Public Health Impact 1.5MB

    https://ntp.niehs.nih.gov/media/impact

    ... The Office of Environmental Health Hazard Assessment (OEHHA) within the California Environmental Protection Agency is adding four chemicals -- androstenedione (CAS No. 63-05-8), ...

  44. Minutes: BSC; Sept. 10-11, 2003 500KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2003/mins2003sept10_508.pdf

    ... ingredient in wormwood), gingko, black cohosh, senna, bladderwrack, green tea, ephedra and two non-herbal dietary supplements, namely chromium picolinate and androstenedione. Dr. ...

  45. Peer Review Panel Report on Evaluation of the LUMI-CELL ER Test... 287KB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edprprept2011.pdf

    ... that there was discordance among the laboratories for six substances: dicofol, fluoranthene, butylphenol, androstenedione, clomiphene citrat, resveratrol. What about dexamethasone? ...

  46. XDS Submission of the LUMI-CELL ER Test Method 3.2MB

    https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/iccvamsubmission28jan05.pdf

    ... 8.31E-07 > 99% Sigma Powder 4-Androstene 63-05-8 Steroid, nonphenolic Hormone 4.00E+07 - ... - Non-Active ND Non-Active N/A N/A 4-Androstenedione 63-05-8 PP - - + - Active Viable ...

  47. Submission of XDS's LUMI-CELL ER High-Throughput System for Screening... 2.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexa/xds-sub.pdf

    ... 8.31E-07 > 99% Sigma Powder 4-Androstene 63-05-8 Steroid, nonphenolic Hormone 4.00E+07 - ... - Non-Active ND Non-Active N/A N/A 4-Androstenedione 63-05-8 PP - - + - Active Viable ...

  48. Historical Controls: Pathology Tables by Route/Vehicle for B6C3F1... 632KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009-05-14-hist-micebyroute.pdf

    ... Southern Research Institute 059902408 12/16/02 729 50 (1) 36(687) 53.8 Androstenedione ... Southern Research Institute 059902408 12/16/02 733 50 (5) 35(690) 65.3 Androstenedione ...

  49. Historical Controls: Pathology Tables by Route/Vehicle for Fischer... 630KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009-05-14-hist-ratsbyroute.pdf

    ... Southern Research Institute 059902407 02/03/03 729 50 (3) 21(661) 518.7 Androstenedione ... Southern Research Institute 059902407 02/03/03 729 50 (5) 38(710) 356.5 Androstenedione ...

  50. Historical Controls: Pathology Tables by Route/Vehicle for B6C3F1... 1019KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/2010-03-22-hist-micebyroute.pdf

    ... Southern Research Institute 059902408 12/16/02 729 50(1) 36(687) 53.8 Androstenedione ... Southern Research Institute 059902408 12/16/02 733 50(5) 35(690) 65.3 Androstenedione ...

 
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