-
Abstract for TR-138 62KB
https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr138
.../Common Names: N1-(3,4-dimethyl-5-isoxazolyl)sulfanilamide Report Date: 1979 Full Report PDF Abstract Sulfisoxazole is an antimicrobial drug that is a derivative of sulfanilamide. ...
-
ICCVAM Test Method Evaluation Report on the LLNA: DA 30.4MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-da/tmer.pdf
... LLNA EC3 (%) (Max. SI) 3 LLNA: DA EC1.8 (%) (Max. SI) 3 Sulfanilamide 4 Pharmaceuticals ... Phenols; Carboxylic Acids NA (2.5) 1 Sulfanilamide 5 Pharmaceuticals Hydrocarbons, ...
-
ICCVAM Test Method Evaluation Report: LLNA BrdU-ELISA 35.6MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-elisa/tmer.pdf
... Carboxylic Acids NC (2.5) NC (1.3) Sulfanilamide Pharmaceuticals Hydrocarbons, Cyclic; ... isophthalate (1,1) AOO 1.26 1.00 Sulfanilamide (1,1) DMF 1.26 1.00 Abbreviations: ACE ...
-
Advancing Flexibility for Defined Approach Guidelines: Developing... 1.2MB
https://ntp.niehs.nih.gov/sites/default/files/2024-03/SOT2024-Sullivan-poster.pdf
... 1B Penicillin G 61-33-6 N 1B 1B 1 1B Phenyl benzoate 93-99-2 N 1B N/A 1 1B Sulfanilamide 63-74-1 N 1B NC NC NC 4-aminobenzoic acid* 150-13-0 Y NC N/A NC NC Citronellol 106-22-9 N ...
-
TR-138: Sulfisoxazole (CASRN 127-69-5) 3.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr138.pdf
... NCI C50022) is an antimicrobial drug that is a derivative of sulfanilamide; the chemical name is N - (3,4-dimethyl-5-isoxazolyl)sulfanilamide (Koralkovas and Burck- halter, 1976). ...
-
Presentation: The Murine Local Lymph Node Assay: BrdU-ELISA 889KB
https://ntp.niehs.nih.gov/iccvam/meetings/implement-2011/acd-present/6-strickland.pdf
... Diethyl phthalate Dimethyl isophthalate Glycerol Hexane 2-Hydroxypropyl methacrylate Isopropanol Lactic acid Methyl salicylate Propylene glycol Salicylic acid Sulfanilamide ...
-
Presentation: The Murine Local Lymph Node Assay: DA 1010KB
https://ntp.niehs.nih.gov/iccvam/meetings/implement-2011/acd-present/7-salicru.pdf
... Lactic acid Methyl salicylate Nickel (II) chloride Propylparaben Salicylic acid Sulfanilamide NICEATM ICCVAM 14 NICEATM-ICCVAM - Advancing Public Health and Animal Welfare ...
-
TR-168: N-(1-Naphthyl)ethylenediamine Dihydrochloride (CASRN... 5.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr168.pdf
... and N-(l-naphthyl)ethylenediamine dihydrochloride is now used to determine the concentrations of potassium, nitrites, and sulfates, as well as sulfanilamide (Windholz, 1976). ...
-
TOX-98: Acetoin (CASRN 513-86-0) and 2,3-Pentanedione (CASRN... 3.0MB
https://ntp.niehs.nih.gov/go/tox098
... an increase of acetylation of sulfanilamide upon feeding acetoin to rabbits or ... 49. Lipmann F. Acetylation of sulfanilamide by liver homogenates and extracts. ...
-
Recommended Performance Standards for the LLNA 2.2MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf
... Liq AOO 95.8 1 X Substituted for sulfanilamide as a false positive (with respect to ... 2 X X X X Don't need two nickel salts Sulfanilamide 63-74-1 Sol DMF NA 1 X X X Excluded as ...
-
Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf
... Sulfanilamide// 4- Aminobenzenesulfonamide// p- Anilinesulfonamide// p- Sulfamidoaniline 63-74-1 benzenesulfonamide// arylamine pharmaceutical (antibacterial [antimicrobial]) - - + ...
-
ICCVAM Test Method Evaluation Report on the Reduced LLNA 21.6MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ld/tmer.pdf
... 118.09 -0.75 Solid Carboxylic Acids EFfCI Sulfanilamide 4-Aminobenzene- sulfonamide; p- Anilinesulfonamide; p-Sulfamidoaniline 63-74-1 172.21 0.40 Solid Amides; Sulfur Compounds; ...
-
Usefulness and Limitations of the LLNA for Potency Categorization... 25.3MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-pot/tmer.pdf
... GmbH, D-33178 Borchen (EFfCI 2006) Sulfanilamide DMF 10.0 25.0 50.0 1.0 1 0.9 NC NC N ... NA 17241 NA NA 1078 (Kligman 1966a) Sulfanilamide 25 Petrolatum 25 1000 14.5 20 NA 17241 ...
-
TR-357: Hydrochlorothiazide (CASRN 58-93-5) in F344/N Rats and... 12.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr357.pdf
... Cancer Inst. 22719- 748. 50. Maren, T.H.; Ellison, A.C. (1971) The terato- logical effect of certain thiadiazoles related to acetazolamide, with a note on sulfanilamide and ...
-
CERHR Monograph: Potential Human Reproductive and Developmental... 1.4MB
https://ntp.niehs.nih.gov/ntp/ohat/egpg/propylene/pg_monograph.pdf
... examined on day 19. Teratogens tested were: bidrin, 6-aminonicotinamide, 3-acetylpyridine, sulfanilamide, 3-amino-1,2,4 triazole, physostigmine sulfate, and nicotine sulfate. ...
-
TR-457: Salicylazosulfapyridine (CASRN 599-79-1) in F344 Rats... 18.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr457.pdf
... Invest. 69,494-497. Straw, D.S. (1981); Somatic mutation, cellular dif- fercntiation, and cancer causation. JNCZ 67,233-241. Svartz, N.(1942). Salazopyrin, a new sulfanilamide ...