-
In Vitro Tox Study Report: Androgenic Receptor Transactivation... 10.7MB
https://ntp.niehs.nih.gov/sites/default/files/2024-04/uv_ar_transactivation_activity_redacted_disclaimer.pdf
... 11 Nilutamide - Agonist ...... 49 Study Number: 9070-100794ARTA Page 8 of 146 FIGURE 12 Nilutamide - ...
-
In Vitro Tox Study Report: Androgenic Transactivation Activity... 24.5MB
https://ntp.niehs.nih.gov/sites/default/files/2024-04/uv_androgenic_transactivation_activity_redacted_disclaimer.pdf
... 59 FIGURE 11 Nilutamide - Agonist ...... 60 FIGURE 11 Nilutamide - Agonist (Continued) ...
-
Addendum to ICCVAM Evaluation of In Vitro Test Methods for Detecting... 2.9MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edaddendfinal.pdf
... Intermediate † ER - ER+ Y binds weakly to ER; being tested in vitro by EPA Nilutamide 63612-50-0 Heterocyclic Compound, Imidazole Pharmaceutical † - AR AR+++ AR± AR## AR ...
-
ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential... 10.6MB
https://ntp.niehs.nih.gov/sites/default/files/iccvam/docs/endo_docs/edfinalrpt0503/edfinrpt.pdf
... Estrene Pharmaceutical Morin 480-16-0 Flavanoid; Flavone; Phenol Dye Nilutamide 63612-50-0 Heterocycle; Imidazole Pharmaceutical p-n-Nonylphenol 104-40-5 Alkylphenol; ...
-
NICEATM Validation Study Report on the MCF-7 Cell Proliferation... 1.8MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/mcf7/mcf7-valstudyreport-19jun12-wcv2-draft.pdf
... NEG 4 Mifepristone NEG (1/1) NT NEG 4 Nilutamide NEG (1/1) NT NEG 4 Oxazepam NEG (1/1) ... Mifepristone POS (1/1) NEG (1/1) NEG 4 Nilutamide POS (1/1) NEG (1/1) NEG 4 Oxazepam POS ...
-
XDS Submission of the LUMI-CELL ER Test Method 3.2MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/iccvamsubmission28jan05.pdf
... 4.00E+07 - 3.91E+04 1.00E+02 - 9.77E-02 3.31E-04 - 3.23E-07 > 95% Sigma Powder Nilutamide 63612-50-0 Heterocycle; Imidazole Pharmaceutical 4.00E+07 - 4.00E+02 1.00E+02 - 1.00E-03 ...
-
Submission of XDS's LUMI-CELL ER High-Throughput System for Screening... 2.4MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexa/xds-sub.pdf
... 4.00E+07 - 3.91E+04 1.00E+02 - 9.77E-02 3.31E-04 - 3.23E-07 > 95% Sigma Powder Nilutamide 63612-50-0 Heterocycle; Imidazole Pharmaceutical 4.00E+07 - 4.00E+02 1.00E+02 - 1.00E-03 ...
-
Endocrine Disruptors Low-Dose Peer Review, October 10-12, 2000 17.3MB
https://ntp.niehs.nih.gov/ntp/pressctr/mtgs_wkshps/2000/lowdosepeerfinalrpt.pdf
... Finally, the non-steroidal antiandrogen, nilutamide, has a weak binding affinity for the ... 5-12, 1991. 3-10 36. Harris, M. G., Coleman, S. G., Faulds, D., and Chrisp, P. Nilutamide. ...
-
ICCVAM Test Method Evaluation Report on the BG1Luc ER TA Test... 17.5MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/bg1lucer-ta-tmer-combined.pdf
... Compound Dye, Natural Product, Pharmaceutical Intermediate 95.3 TCI America Nilutamide 63612-50-0 Heterocyclic Compound, Imidazole Pharmaceutical 100.0 Sigma-Aldrich Corporation ...
-
CERHR Update on the Reproductive and Developmental Toxicity of... 4.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/phthalates/dehp/dehp-monograph.pdf
... The.cell.line.showed.an.81%.decrease.in.dihydrotestosterone-induced.luciferase.activity.after.exposure. to.the.positive.control.nilutamide,.an.androgen.receptor.antagonist,.at.10.-...
-
TR-597: 2-Hydroxy-4-methoxybenzophenone (CASRN 131-57-7) Administered... 3.2MB
https://ntp.niehs.nih.gov/go/tr597
... Dihydrotestosterone (DHT), nilutamide (Nil), dichlorodiphenyldichloroethylene (p,p'-DDE, ... Fit Reference Agents UV Filter DDE Nilutamide 2H4MBP EHMC RPC min Exp. 1 10.3 ± 0.3 ...