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TR-341: Nitrofurantoin (CASRN 67-20-9) in F344/N Rats and B6C3F1Mice... 10.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr341.pdf
1 (""l '<J TOXICOLOGY AND CARCINOGENESIS STUDIES OF NITROFURANTOIN (CAS NO. 67-20-9) IN F344/N RATS AND B6C3FI MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES ...
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Abstract for TR-341 68KB
https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr341
Abstract for TR-341 Toxicology and Carcinogenesis Studies of Nitrofurantoin in F344/N Rats and B6C3F1 Mice (Feed Studies) CASRN: 67-20-9 Chemical Formula: C8H6N4O5 Molecular ...
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Abstract for RACB89063 59KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb89063
3abs Abstract for RACB89063 Nitrofurantoin: Reproduction and Fertility Assessment in CD-1 Mice When Administered via Feed CASRN: 67-20-9 Chemical Formula: C8H6N4O5 Molecular ...
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Minutes: BSC TRRS; July 14, 1987 821KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1987/july/87july14trrsmin_508.pdf
Acid Orange 3 6375-74-6 Gavage 3 Dichlorvos 62-73-7 Gavage 4 Erythromycin Stearate 643-22-1 Feed 6 Nitrofurantoin 67-20-9 Feed 7 Nitrofurazone 59-87-0 Feed 10 Penicillin VK ...
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Target Organs and Levels of Evidence for TR-341 57KB
https://ntp.niehs.nih.gov/data/tr/300s/tr341levels
Target Organs and Levels of Evidence for TR-341 Toxicology and Carcinogenesis Studies of Nitrofurantoin (CASRN 67-20-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) Chemical ...
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Minutes: BSC TRRS; April 18, 1988 4.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1988/apr/88apr18trrsmins_508.pdf
Growth of Transplantable Rat Leukemia Nitrofurantoin a Update and Reevaluation of Further ... French said the data indicate that male rats administered nitrofurantoin in feed at o, ...
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Reproductive Abstracts 200KB
https://ntp.niehs.nih.gov/publications/abstracts/repro
... (CASRN: 77-09-8) in CD-1 Swiss Mice 1990 Reproductive RACB89063 Nitrofurantoin Nitrofurantoin (CASRN: 67-20-9): Reproduction and Fertility Assessment in CD-1 Mice When ...
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TR-402: Furan (CASRN 110-00-9) in F344 Rats and B6C3F1 Mice(Gavage... 31.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr402.pdf
... However, five furan compounds (furfural, benzofuran, furosemide, nitrofurantoin, and ... Dietary administration of nitrofurantoin to F344/N rats and B6C3F 1 mice for 2 years was ...
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Study Abstracts 373KB
https://ntp.niehs.nih.gov/publications/abstracts
... (CASRN: 77-09-8) in CD-1 Swiss Mice 1990 Reproductive RACB89063 Nitrofurantoin Nitrofurantoin (CASRN: 67-20-9): Reproduction and Fertility Assessment in CD-1 Mice When ...
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TR-337: Nitrofurazone (CASRN 59-87-0) in F344/N Rats and B6C3F1Mice... 10.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr337.pdf
... Dr. Kari re- marked that in the study of nitrofurantoin, malignant granulosa cell tumors ... Suppl. 1:3-142. 32. Hoener, B.-A.;Krueger, T.R. (1984) Disposi- tion of nitrofurantoin and ...
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TR-392: Chlorinated Water (CASRNs. 7782-50-5 and 7681-52-9) and... 75.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr392.pdf
... and carcinogenesis studies of nitrofurantoin in rats (NTP, 1989a), in which the ... In contrast to the nitrofurantoin studies, the step sections of kidneys of male mice ...
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TR-452: 2,2-Bis(Bromomethyl)-1,3-Propanediol (FR-1138) (CASRN... 31.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr452.pdf
... Pigment Red 3 1/50 0/50 2/50 1/50 Nitrofurantoin 0/50 3/50 4/50 0/50 o-Nitroanisole 1/.../50 C.I. Pigment Red 3 0/50 0/50 4/50 Nitrofurantoin 1/50 0.50 8/50 o-Nitroanisole 1/50 0/...
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TR-411: C.I. Pigment Red 23 (CASRN 6471-49-4) in F344 Rats and... 15.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr411.pdf
... o f nephrotoxic chemicals such as nitrofurantoin (NTF', 1989a), furosemide (1989c), ... response in male rats treated with nitrofurantoin for 2 years, the observed incidence o ...
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TR-442: p-Nitrobenzoic Acid (CASRN 62-23-7) in F344/N Rats and... 15.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr442.pdf
... Interference of the reduction of p-nitrobenzoate in E. coli by nitrofurantoin. Xenobiotica ... Acetate 0/50 0/50 0150 0/50 0/50 0/50 Nitrofurantoin C.I. Pigment Red 3 0/50 0/50 0/50 1/...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... EE Equivocal Evidence SE Some Evidence P Clear Evidence TR-341 04/18/88 Nitrofurantoin 67-20-9 SE Some Evidence NE No Evidence NE No Evidence P Clear Evidence TR-340 10/04/88 ...
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TR-407: C.I. Pigment Red 3 (CASRN 2425-85-6) in F344/N Rats and... 15.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr407.pdf
... Research Institute C.I.PigmentRed 3 Nitrofurantoin o-Nitroanisole Polysorbate 80 ... Research Institute C.I.PigmentRed 3 Nitrofurantoin o-Nitroanisole Polysorbate 80 ...
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TR-318: Ampicillin Trihydrate (CASRN 7177-48-2) in F344/N Rats... 10.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr318.pdf
... Similar tests have been used to evaluate the mutagenic activity of other antimicrobials, in- cluding nitrofurantoin and streptomycin sulfate (Haworth et al., 1983). Ampicillin was ...
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Technical Reports 902KB
https://ntp.niehs.nih.gov/publications/reports/tr
... Report TR-341 PDF (10.04 MB) Toxicology and Carcinogenesis Studies of Nitrofurantoin (CASRN 67-20-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1989 Technical Report TR-340 ...
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TR-416: o-Nitroanisole (CASRN 91-23-6) in F344 Rats and B6C3F1... 24.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr416.pdf
... Nitrofurantoin o-Nitroanisole Polysorbate 80 Rhodamine 6G Roxarsone Overall Historical ... Pigment Red 3 0/50 0/50 Nitrofurantoin 0/50 0/50 o-Nitroanisole 0/50 0/50 Polysorbate 80 ...
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TR-528: 2,2-bis(Bromomethyl)-1,3-Propanediol, Nitromethane, and... 5.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr528.pdf
... Nitromethane is used in a variety of solvent applications, such as solvent- extraction separation of aromatics from aliphatic com- pounds, in the crystallization of nitrofurantoin, ...
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Study Reports 1.1MB
https://ntp.niehs.nih.gov/publications/reports
... Report TR-341 PDF (10.04 MB) Toxicology and Carcinogenesis Studies of Nitrofurantoin (CASRN 67-20-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1989 Technical Report TR-340 ...
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TR-413: Ethylene Glycol (CASRN 107-21-1) in B6C3F1Mice (Feed... 11.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr413.pdf
... 2/50 Ethylene Glycol 0/54 0/54 0/54 Nitrofurantoin 2/50 0150 2/50 o-Nitroanisole 9/50 1/... Red 3 3/50 Ethylene Glycol 0/50 Nitrofurantoin 2/50 o-Nitroanisole 4/50 Polysorbate ...
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Toxicology/Carcinogenicity 1.1MB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox
... TR-341 PDF (10.04 MB) Toxicology and Carcinogenesis Studies of Nitrofurantoin (CASRN 67-20-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1989 Long-Term Carcinogenicity ...
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TR-498: p-Nitrotoluene (CASRN 99-99-0) in F344/N Rats and B6C3F1Mice... 10.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr498.pdf
... Toxicology and Carcinogenesis Studies of Nitrofurantoin (CAS No. 67-20-9) in F344/N Rats and B6C3F 1 Mice (Feed Studies). Technical Report Series No. 341. NIH Publication No. ...
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TR-409: Quercetin (CASRN 117-39-5) in F344 Rats (Feed Studies... 9.6MB
https://ntp.niehs.nih.gov/go/tr409
... NeoJasms NTP and Structure Number . d Rats Q Rats d Mice Q Mice h h o m h Results Nitrofurantoin 341 + + Ochratoxin 358 + + NT NT Phenylbutazone 367 + Tetrachloroethylene 311 + C ...
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TR-465: Phenolphthalein (CASRN 77-09-8) in F344 Rats and B6C3F1Mice... 18.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr465.pdf
... 1989a), acenaphthene (NCI, 1978), nitrofurantoin (NTP, 1989b), nitrofurazone (NTP, ... Toxicology and Studies Carcinogenesis of Nitrofurantoin (CAS No. 67-20-9) in F344/N Rats ...
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TR-329: 1,2-Epoxybutane (CASRN 106-88-7) in F344/N Rats and B6C3F1Mice... 10.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr329.pdf
... Biophys. Res. Commun. 66:520-525. 59. Rosenkranz, H.S.; Speck, W.T. (1976) Activa- tion of nitrofurantoin to a mutagen by rat liver nitroreductase. Biochem. Pharmacol. 25:1555- ...
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TR-362: 4-Vinyl-1-cyclohexene Diepoxide (CASRN 106-87-6) in F344... 14.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr362.pdf
......... Nitrofurantoin Sites of carcinogenicity Male rat--kidney; female rat-none; NTPTR341iNTP. 1989bi ...
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TR-367: Phenylbutazone (CASRN 50-33-9) in F344/N Rats and B6C3F1Mice... 10.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr367.pdf
... STEP-Sl~CTIONING IN SELECTED CONTROL GROUPS OF MALE F344/N RATS IN NTP STUDIES Nitrofurantoin (a) Furosemide (b) Toluene (c) Phenilbutazone (d) Total Lesion Single (e) Number ...
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TR-415: Polysorbate 80 (CASRN 9005-65-6) in F344/N Rats and B6C3F1Mice... 12.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr415.pdf
... Benign Pheochromocytoma . . Historical Incidence at Southern Research Insitute C I Pigment Red 3 w 5 0 Nitrofurantoin 23/50 o-Nitroanisole 7/49 Polysorbate 80 21/50 Rhodamine 6 G ...
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TR-371: Toluene (CASRN108-88-3) in F344/N Rats and B6C3F1Mice... 15.6MB
https://ntp.niehs.nih.gov/go/tr371
... 1/50 to 3/50; NTP, 1989d) or three (nitrofurantoin, 0/50 to 3/50; NTP, 1989e). ... Toxicology and Carcinogenesis Studies of Nitrofurantoin in F344/N Rats and B6C3F1 Mice. ...
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TR-417: p-Nitrophenol (CASRN 100-02-7) in Swiss Webster Mice... 7.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr417.pdf
... 377 o-Chloroknzalmalononitrile 340 Iodinated Glycerol 378 Benzaldehyde 341 Nitrofurantoin 379 2-Chloroacetophenone 342 Dichlorvos 386) Epinephrine Hydrochloride 343 Benzyl ...
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TR-444: Initiation/Promotion Study of o-Benzyl-p-Chlorophenol... 6.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr444.pdf
... VK Nitrofurazone Erythromycin Stearate 2-Amino-4-nitrophenol Iodinated Glycerol Nitrofurantoin Dichlorvos Benzyl Alcohol Tetracycline Hydrochloride Roxarsone Chloroethane ...
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TR-389: Sodium Azide (CASRN 26628-22-8) in F344 Rats (Gavage... 8.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr389.pdf
... CHEMICAL 338 Eiythromycin Stearate 339 2-Amino-4-nitrophenol 340 lodinated Gtycerol 341 Nitrofurantoin 342 Dichlorvos 343 Benzyl Alcohol 344 Tetracycline Hydrochloride 345 ...
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TR-410: Naphthalene (CASRN 91-20-3) in B6C3F1Mice (Inhalation... 8.6MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr410.pdf
... REPORTS PRINTED AS OF MARCH 1992 TR No. CHEMICAL TR No. CHEMICAL 341 340 339 338 Nitrofurantoin Iodinated Glycerol 2-Amino-4-nitrophend Erythromycin Stearate 372 371 370 369 ...
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TR-399: Titanocene Dichloride (CASRN 1271-19-8) in F344/N Rats... 8.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr399.pdf
... 360 361 362 CHEMICAL Erythromycin Stearate 2-Amino4-nitrophenol Iodinated Glycerol Nitrofurantoin Dichlorvos Benzyl Alcohol Tetracycline Hydrochloride Raxarsone Chlomthane ...
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TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB
https://ntp.niehs.nih.gov/go/tr518
... Subsulfide 453 p-Nitroaniline 418 o-Nitroanisole 416 p-Nitrobenzoic Acid 442 Nitrofurantoin 341 Nitrofurazone 337 Nitromethane 461 p-Nitrophenol 417 o-Nitrotoluene 504 ...
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TR-387: dl-Amphetamine Sulfate (CASRN 60-13-9) in F344/N Rats... 10.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr387.pdf
... CHEMICAL 338 339 340 341 Erythromycin Stearate 2-Amino-4-nitrophenol Iodinated Glycerol Nitrofurantoin 362 363 364 365 4-Vinyl-1-Cyclohaene Diepoxide Bromoethane (Ethyl Bromide) ...
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TR-400: 2,3-Dibromo-1-Propanol (CASRN 96-13-9) in F344/N Rats... 11.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr400.pdf
... 385 Methyl Bromide 340 Iodinated Glycerol 386 Tetranitromethane 341 Nitrofurantoin 387 Amphetamine Sulfate 342 Dichlorvos 388 Ethylene Thiourea 343 Benzyl Alcohol ...
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TR-385: Methyl Bromide (CASRN 74-83-9) in B6C3F1Mice (Inhalation... 7.3MB
https://ntp.niehs.nih.gov/go/tr385
... 21 86 46.8 53 45.5 97 52 45.7 98 53 31.1 67 20
90 48.1 51 46.3 96 52 47.0 98 50 31.7 66 20 ... Iodinated Glycerol Nitrofurantoin Dichlorvos 366 367 368 369 370 ...
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TR-388: Ethylene Thiourea (CASRN 96-45-7) in F344 Rats and B6C3F1Mice... 13.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr388.pdf
... TRNa CHEMICAL 333 339 340 341 342 ~rythromycin Stearate &Amino-4-nitrophend Iodinated Glyctrol Nitrofurantoin Dichlorvos 366 367 368 369 370 H y m - Phenylbutazone Nalidixic Add ...
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TR-390: 3,3'-Dimethylbenzidine Dihydrochloride (CASRN 612-82... 12.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr390.pdf
... 364 363 Rhodamine 6G (C.I. Basic Red 1) Bromoethane (Ethyl Bromide) 341 Nitrofurantoin 365 Pentaerythritol Tetranitrate 342 Dichlorvos 366 Hydroquinone 343 Benzyl ...
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TR-391: Tris(2-chloroethyl) Phosphate (CASRN 115-96-8) in F344... 11.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr391.pdf
... TR No. CHEMICAL TR Na CHEMICAL 341 340 339 338 Nitrofurantoin Iodinated Glycerol 2-Amino4-nitrophenol Erfhromycin Stearate 365 364 363 362 Pentaerythritol Tetranitrate Rhodamine 6G ...
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TR-395: Probenecid (CASRN 57-66-9) in F344/N Rats and B6C3F1Mice... 16.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr395.pdf
... 6G (C.I. Basic Red 1) 340 Iodinated Glycerol 365 Pentaerythritol Tetranitrate 341 Nitrofurantoin 366 Hydroquinone 342 Dichlorvos 367 Phenylbutazone 343 Benzyl Alcohol 368 ...
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TR-396: Monochloroacetic Acid (CASRN 79-11-8) in F344/N Rats... 14.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr396.pdf
... CHEMICAL 338 Erythromycin Stearate 364 Rhodemine6G(CLBasicRedl) 339 ZAmind-nitrophend 365 P c n e t d Tetranitrate 340 Iodinated Glycerol 366 m - 341 Nitrofurantoin 367 Phcnylbumne ...
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TR-397: C.I. Direct Blue 15 (CASRN 2429-74-5) in F344 Rats (Drinking... 13.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr397.pdf
... CHEMICAL 338 Etythromycin Stearate 371 Toluene 354 353 352 351 350 349 348 347 346 345 344 343 342 341 340 339 DicMowoa Nitrofurantoin Iodinated Glycerol ZAmino-4-nitrophenol ...
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TR-405: C.I. Acid Red 114 (CASRN 6459-94-5) in F344/N Rats (Drinking... 12.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr405.pdf
... CHEMICAL 338 Erythromycin Stearate 339 ZAmino4-nitrophenol 340 Iodinated Glycerol 341 Nitrofurantoin 342 Dichlorvos 343 Eknzyl Alcohol 344 Tetracycline Hydrochloride 345 Raxarsone ...
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TR-408: Mercuric Chloride (CASRN 7487-94-7) in F344 Rats and... 12.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr408.pdf
... VK Nitrofurazone Erythromycin Stearate 2-Amino-4-nitrophenol Iodinated Glycerol Nitrofurantoin Dichlorvos Benzyl Alcohol Tetracycline Hydrochloride Roxarsone Chloroethane ...
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TR-414: Pentachloroanisole (CASRN 1825-21-4) in F344 Rats and... 15.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr414.pdf
... 377 o-Chloro~nzalmlononitrile 340 Iadinated Glycerol 378 Benzaldehyde 3 4 1 Nitrofurantoin 379 2-Chlomacetophenone 342 Dichlorvoe 380 Epinephrine Hydrochloride 343 Benzyl ...
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TR-479: Coconut Oil Acid Diethanolamine Condensate (CASRN 68603... 7.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr479.pdf
... Hexahydrate Nickel Subsulfide p-Nitroaniline o-Nitroanisole p-Nitrobenzoic Acid Nitrofurantoin Nitrofurazone Nitromethane p-Nitrophenol Ochratoxin A 388 223 208 402 382 482 356 ...