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TR-341: Nitrofurantoin (CASRN 67-20-9) in F344/N Rats and B6C3F1Mice... 10.0MB
https://ntp.niehs.nih.gov/go/tr341
1 (""l '<J TOXICOLOGY AND CARCINOGENESIS STUDIES OF NITROFURANTOIN (CAS NO. 67-20-9) IN F344/N RATS AND B6C3FI MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES ...
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Nitrofurantoin 10382-W 24KB
https://ntp.niehs.nih.gov/go/ts-10382-w
Nitrofurantoin 10382-W CASRN: 67-20-9 Formula: C8-H6-N4-O5 Synonyms/Common Names 1-(((5-Nitro-2-furanyl)methylene)amino)-2,4-imidazolidinedione (9CI) Short-Term Toxicity 14-Day ...
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TR 341 Rat Pathology Tables 594KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr341/path/05051rp09/index.html
Study Type: CHRONIC NITROFURANTOIN Date: 05/06/97 Route: DOSED FEED Time: 13:25:52 Facility: Southern Research Institute Chemical CAS #: 67-20-9 Lock Date: None Cage Range: ...
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TR 341 Mouse Pathology Tables 441KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr341/path/05051mp04/index.html
Study Type: CHRONIC NITROFURANTOIN Date: 05/06/97 Route: DOSED FEED Time: 13:54:59 Facility: Southern Research Institute Chemical CAS #: 67-20-9 Lock Date: None Cage Range: ...
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TR 341 Rat Pathology Tables 450KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr341/path/05051rp04/index.html
Study Type: CHRONIC NITROFURANTOIN Date: 05/06/97 Route: DOSED FEED Time: 13:02:22 Facility: Southern Research Institute Chemical CAS #: 67-20-9 Lock Date: None Cage Range: ...
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TR 341 Mouse Pathology Tables 422KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr341/path/05051mp09/index.html
Study Type: CHRONIC NITROFURANTOIN Date: 05/06/97 Route: DOSED FEED Time: 15:05:03 Facility: Southern Research Institute Chemical CAS #: 67-20-9 Lock Date: None Cage Range: ...
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TR 341 Rat Pathology Tables 209KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr341/path/05051rp08/index.html
PEIRPT08 LAB: Southern Research Inst NITROFURANTOIN DATE: 09/07/94 EXPERIMENT: 05051 ... C#: C55196 PATHOLOGIST: R. THOMPSON CAS: 67-20-9 ---...
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Abstract for TR-341 30KB
https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr341/index.html
Abstract for TR-341 Toxicology and Carcinogenesis Studies of Nitrofurantoin in F344/N Rats and B6C3F1 Mice (Feed Studies) CASRN: 67-20-9 Chemical Formula: C8H6N4O5 Molecular ...
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TR 341 Mouse Pathology Tables 146KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr341/path/05051mp08/index.html
PEIRPT08 LAB: Southern Research Inst NITROFURANTOIN DATE: 09/07/94 EXPERIMENT: 05051 ... C#: C55196 PATHOLOGIST: H. GILES CAS: 67-20-9 ---...
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TR 341 Rat Pathology Tables 118KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr341/path/05051rp03/index.html
LESIONS BY ANATOMIC SITE (a) NITROFURANTOIN NTP Experiment-Test: 05051-01 Report: ... Facility: Southern Research Institute Chemical CAS #: 67-20-9 Lock Date: None Cage Range: ...
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Minutes: BSC TRRS; July 14, 1987 821KB
https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/trrs/1987/july/87july14trrsmin_508.pdf
Acid Orange 3 6375-74-6 Gavage 3 Dichlorvos 62-73-7 Gavage 4 Erythromycin Stearate 643-22-1 Feed 6 Nitrofurantoin 67-20-9 Feed 7 Nitrofurazone 59-87-0 Feed 10 Penicillin VK ...
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TR 341 Mouse Pathology Tables 85KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr341/path/05051mp03/index.html
LESIONS BY ANATOMIC SITE (a) NITROFURANTOIN NTP Experiment-Test: 05051-02 Report: ... Facility: Southern Research Institute Chemical CAS #: 67-20-9 Lock Date: None Cage Range: ...
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TR 341 Mouse Pathology Tables 81KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr341/path/05051mp05/index.html
SITE (SYSTEMIC LESIONS ABRIDGED) (a) NITROFURANTOIN NTP Experiment-Test: 05051-02 Report: ... Facility: Southern Research Institute Chemical CAS #: 67-20-9 Lock Date: None Cage Range: ...
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TR 341 Rat Pathology Tables 83KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr341/path/05051rp05/index.html
SITE (SYSTEMIC LESIONS ABRIDGED) (a) NITROFURANTOIN NTP Experiment-Test: 05051-01 Report: ... Facility: Southern Research Institute Chemical CAS #: 67-20-9 Lock Date: None Cage Range: ...
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Abstract for RACB89063 22KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb89063/index-73.html
3abs Abstract for RACB89063 Nitrofurantoin: Reproduction and Fertility Assessment in CD-1 Mice When Administered via Feed CASRN: 67-20-9 Chemical Formula: C8H6N4O5 Molecular ...
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TR 341 Mouse Pathology Tables 43KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr341/path/05051mp11/index.html
05051 NITROFURANTOIN TIME: 14:53:11 TEST: 02 CAGES FROM 0000 TO LAST CAGE PAGE: 1 TEST TYPE: CHRONIC ROUTE: DOSED FEED NTP C#: C55196 CONT: NOIES28024 CAS: 67-20-9 PATHOLOGIST: ...
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TR 341 Rat Pathology Tables 44KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr341/path/05051rp11/index.html
05051 NITROFURANTOIN TIME: 07:15:02 TEST: 01 CAGES FROM 0000 TO LAST CAGE PAGE: 1 TEST TYPE: CHRONIC ROUTE: DOSED FEED NTP C#: C55196 CONT: NOIES28024 CAS: 67-20-9 PATHOLOGIST: ...
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Target Organs and Levels of Evidence for TR-341 21KB
https://ntp.niehs.nih.gov/data/tr/300s/tr341levels/index.html
Target Organs and Levels of Evidence for TR-341 Toxicology and Carcinogenesis Studies of Nitrofurantoin (CASRN 67-20-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) Chemical ...
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TR-341 Pathology Tables and Curves 22KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr341/index.html
9158 TR-341 Pathology Tables and Curves TR-341 NITROFURANTOIN Pathology Tables - Rats P03 - Incidence Rates of Non-Neoplastic Lesions By Anatomic Site P04 - Individual Animal Tumor ...
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Nomination Summary for Control chemical for salmonella assay... 32KB
https://ntp.niehs.nih.gov/go/nm-n78001
4,4'-Methylenebis(2-chloroaniline), Nitrofurantoin, N-Nitrosopiperidine, Potassium ... Agent Name: 4,4'-Methylenebis(2-chloroaniline) Testing Status Back to Top CASRN: 67-20-9 ...
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Minutes: BSC TRRS; April 18, 1988 4.9MB
https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/trrs/1988/apr/88apr18trrsmins_508.pdf
Growth of Transplantable Rat Leukemia Nitrofurantoin a Update and Reevaluation of Further ... French said the data indicate that male rats administered nitrofurantoin in feed at o, ...
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TR-402: Furan (CASRN 110-00-9) in F344 Rats and B6C3F1 Mice(Gavage... 31.9MB
https://ntp.niehs.nih.gov/go/tr402
... However, five furan compounds (furfural, benzofuran, furosemide, nitrofurantoin, and ... Dietary administration of nitrofurantoin to F344/N rats and B6C3F 1 mice for 2 years was ...
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Study Abstracts 243KB
https://ntp.niehs.nih.gov/publications/abstracts/index.html
... 109-86-4) in Sprague-Dawley Rats, Litter Two 1990 Reproductive RACB89063 Nitrofurantoin Nitrofurantoin (CASRN: 67-20-9): Reproduction and Fertility Assessment in CD-1 Mice When ...
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TR-337: Nitrofurazone (CASRN 59-87-0) in F344/N Rats and B6C3F1Mice... 10.7MB
https://ntp.niehs.nih.gov/go/tr337
... Dr. Kari re- marked that in the study of nitrofurantoin, malignant granulosa cell tumors ... Suppl. 1:3-142. 32. Hoener, B.-A.;Krueger, T.R. (1984) Disposi- tion of nitrofurantoin and ...
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Management Status Report Produced from NTP Chemtrack System 311KB
https://ntp.niehs.nih.gov/publications/msr/msr.pdf
... Nitrofen 1836-75-5 46 16 Nitrofen 1836-75-5 46 16 Nitrofurantoin 67-20-9 46 16 Nitrofurazone 59-87-0 46 16 Nitrofurazone 59-87-0 50 17 Nitromethane 75-52-5 46 16 1-Nitronaphthalene ...
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TR-392: Chlorinated Water (CASRNs. 7782-50-5 and 7681-52-9) and... 75.1MB
https://ntp.niehs.nih.gov/go/tr392
... and carcinogenesis studies of nitrofurantoin in rats (NTP, 1989a), in which the ... In contrast to the nitrofurantoin studies, the step sections of kidneys of male mice ...
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TR-411: C.I. Pigment Red 23 (CASRN 6471-49-4) in F344 Rats and... 15.0MB
https://ntp.niehs.nih.gov/go/tr411
... o f nephrotoxic chemicals such as nitrofurantoin (NTF', 1989a), furosemide (1989c), ... response in male rats treated with nitrofurantoin for 2 years, the observed incidence o ...
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TR-452: 2,2-Bis(Bromomethyl)-1,3-Propanediol (FR-1138) (CASRN... 31.1MB
https://ntp.niehs.nih.gov/go/tr452
... Pigment Red 3 1/50 0/50 2/50 1/50 Nitrofurantoin 0/50 3/50 4/50 0/50 o-Nitroanisole 1/.../50 C.I. Pigment Red 3 0/50 0/50 4/50 Nitrofurantoin 1/50 0.50 8/50 o-Nitroanisole 1/50 0/...
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NTP Technical Reports Index 282KB
https://ntp.niehs.nih.gov/data/tr/index.html
... Benzyl Alcohol 100-51-6 TR-342 07/14/87 Dichlorvos 62-73-7 TR-341 04/18/88 Nitrofurantoin 67-20-9 TR-340 10/04/88 Iodinated Glycerol 5634-39-9 TR-339 07/14/87 ...
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TR-442: p-Nitrobenzoic Acid (CASRN 62-23-7) in F344/N Rats and... 15.9MB
https://ntp.niehs.nih.gov/go/tr442
... Interference of the reduction of p-nitrobenzoate in E. coli by nitrofurantoin. Xenobiotica ... Acetate 0/50 0/50 0150 0/50 0/50 0/50 Nitrofurantoin C.I. Pigment Red 3 0/50 0/50 0/50 1/...
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TR-407: C.I. Pigment Red 3 (CASRN 2425-85-6) in F344/N Rats and... 15.9MB
https://ntp.niehs.nih.gov/go/tr407
... Research Institute C.I.PigmentRed 3 Nitrofurantoin o-Nitroanisole Polysorbate 80 ... Research Institute C.I.PigmentRed 3 Nitrofurantoin o-Nitroanisole Polysorbate 80 ...
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Management Status Report: Reference 16 LT 375KB
https://ntp.niehs.nih.gov/go/msr-16lt
... (9CI) 1836-75-5 FEED R1 M3 TR-026 Nitrofurantoin 1-(((5-Nitro-2-furanyl)methylene)amino)-2,4-imidazolidinedione (9CI) 67-20-9 FEED R2 M3 TR-341 Nitrofurazone ...
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TR-318: Ampicillin Trihydrate (CASRN 7177-48-2) in F344/N Rats... 10.7MB
https://ntp.niehs.nih.gov/go/tr318
... Similar tests have been used to evaluate the mutagenic activity of other antimicrobials, in- cluding nitrofurantoin and streptomycin sulfate (Haworth et al., 1983). Ampicillin was ...
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Substance Search 453KB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/status/index.html
... 2-Nitroethanol 2-Nitro-2-ethyl-1,3-propanediol Nitrofen 2-Nitrofluorene Nitrofurantoin Nitrofurazone N-(4-(5-Nitro-2-furyl)-2-thiazolyl)formamide Nitrogen mustard ...
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TR-413: Ethylene Glycol (CASRN 107-21-1) in B6C3F1Mice (Feed... 11.1MB
https://ntp.niehs.nih.gov/go/tr413
... 2/50 Ethylene Glycol 0/54 0/54 0/54 Nitrofurantoin 2/50 0150 2/50 o-Nitroanisole 9/50 1/... Red 3 3/50 Ethylene Glycol 0/50 Nitrofurantoin 2/50 o-Nitroanisole 4/50 Polysorbate ...
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TR-416: o-Nitroanisole (CASRN 91-23-6) in F344 Rats and B6C3F1... 24.5MB
https://ntp.niehs.nih.gov/go/tr416
... Nitrofurantoin o-Nitroanisole Polysorbate 80 Rhodamine 6G Roxarsone Overall Historical ... Pigment Red 3 0/50 0/50 Nitrofurantoin 0/50 0/50 o-Nitroanisole 0/50 0/50 Polysorbate 80 ...
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TR-528: 2,2-bis(Bromomethyl)-1,3-Propanediol, Nitromethane, and... 5.5MB
https://ntp.niehs.nih.gov/go/tr528
... Nitromethane is used in a variety of solvent applications, such as solvent- extraction separation of aromatics from aliphatic com- pounds, in the crystallization of nitrofurantoin, ...
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Toxicology/Carcinogenicity 693KB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox/index.html
... TR-341 PDF (10MB) Toxicology and Carcinogenesis Studies of Nitrofurantoin (CASRN 67-20-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1989 Long-Term Carcinogenicity ...
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TR-498: p-Nitrotoluene (CASRN 99-99-0) in F344/N Rats and B6C3F1Mice... 10.3MB
https://ntp.niehs.nih.gov/go/tr498
... Toxicology and Carcinogenesis Studies of Nitrofurantoin (CAS No. 67-20-9) in F344/N Rats and B6C3F 1 Mice (Feed Studies). Technical Report Series No. 341. NIH Publication No. ...
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Study Reports 606KB
https://ntp.niehs.nih.gov/publications/reports/index.html
... Report TR-341 PDF (10MB) Toxicology and Carcinogenesis Studies of Nitrofurantoin (CASRN 67-20-9) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1989 Technical Report TR-365 ...
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TR-409: Quercetin (CASRN 117-39-5) in F344 Rats (Feed Studies... 9.6MB
https://ntp.niehs.nih.gov/go/tr409
... NeoJasms NTP and Structure Number . d Rats Q Rats d Mice Q Mice h h o m h Results Nitrofurantoin 341 + + Ochratoxin 358 + + NT NT Phenylbutazone 367 + Tetrachloroethylene 311 + C ...
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TR-367: Phenylbutazone (CASRN 50-33-9) in F344/N Rats and B6C3F1Mice... 10.5MB
https://ntp.niehs.nih.gov/go/tr367
... STEP-Sl~CTIONING IN SELECTED CONTROL GROUPS OF MALE F344/N RATS IN NTP STUDIES Nitrofurantoin (a) Furosemide (b) Toluene (c) Phenilbutazone (d) Total Lesion Single (e) Number ...
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TR-465: Phenolphthalein (CASRN 77-09-8) in F344 Rats and B6C3F1Mice... 18.9MB
https://ntp.niehs.nih.gov/go/tr465
... 1989a), acenaphthene (NCI, 1978), nitrofurantoin (NTP, 1989b), nitrofurazone (NTP, ... Toxicology and Studies Carcinogenesis of Nitrofurantoin (CAS No. 67-20-9) in F344/N Rats ...
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TR-329: 1,2-Epoxybutane (CASRN 106-88-7) in F344/N Rats and B6C3F1Mice... 10.0MB
https://ntp.niehs.nih.gov/go/tr329
... Biophys. Res. Commun. 66:520-525. 59. Rosenkranz, H.S.; Speck, W.T. (1976) Activa- tion of nitrofurantoin to a mutagen by rat liver nitroreductase. Biochem. Pharmacol. 25:1555- ...
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TR-362: 4-Vinyl-1-cyclohexene Diepoxide (CASRN 106-87-6) in F344... 14.5MB
https://ntp.niehs.nih.gov/go/tr362
......... Nitrofurantoin Sites of carcinogenicity Male rat--kidney; female rat-none; NTPTR341iNTP. 1989bi ...
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Draft TR-597: 2-Hydroxy-4-methoxybenzophenone (CASRN 131-57-7... 4.7MB
https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2019/december/tr597draft.pdf
... lesion in several strains of rats (including the Sprague Dawley) that can be exacerbated by chemical agents such as nitrofurantoin and agents that cause systemic hypertension 98 . ...
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TR-415: Polysorbate 80 (CASRN 9005-65-6) in F344/N Rats and B6C3F1Mice... 12.2MB
https://ntp.niehs.nih.gov/go/tr415
... Benign Pheochromocytoma . . Historical Incidence at Southern Research Insitute C I Pigment Red 3 w 5 0 Nitrofurantoin 23/50 o-Nitroanisole 7/49 Polysorbate 80 21/50 Rhodamine 6 G ...
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TR-371: Toluene (CASRN108-88-3) in F344/N Rats and B6C3F1Mice... 15.6MB
https://ntp.niehs.nih.gov/go/tr371
... 1/50 to 3/50; NTP, 1989d) or three (nitrofurantoin, 0/50 to 3/50; NTP, 1989e). ... Toxicology and Carcinogenesis Studies of Nitrofurantoin in F344/N Rats and B6C3F1 Mice. ...
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TR-417: p-Nitrophenol (CASRN 100-02-7) in Swiss Webster Mice... 7.4MB
https://ntp.niehs.nih.gov/go/tr417
... 377 o-Chloroknzalmalononitrile 340 Iodinated Glycerol 378 Benzaldehyde 341 Nitrofurantoin 379 2-Chloroacetophenone 342 Dichlorvos 386) Epinephrine Hydrochloride 343 Benzyl ...
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TR-444: Initiation/Promotion Study of o-Benzyl-p-Chlorophenol... 6.4MB
https://ntp.niehs.nih.gov/go/tr444
... VK Nitrofurazone Erythromycin Stearate 2-Amino-4-nitrophenol Iodinated Glycerol Nitrofurantoin Dichlorvos Benzyl Alcohol Tetracycline Hydrochloride Roxarsone Chloroethane ...