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146 results found for "68-19-9".

  1. Identifying Research Needs for Assessing Safe Use of High Intakes... 70KB

    https://ntp.niehs.nih.gov/whatwestudy/assessments/noncancer/completed/folate

    44 Identifying Research Needs for Assessing Safe Use of High Intakes of Folic Acid hand drawing the chemical structure of Folic Acid Topic Overview CASRN: 59-30-3 Status: ...

  2. Presentation: Mechanisms of Acute Toxicity 2.4MB

    https://ntp.niehs.nih.gov/iccvam/meetings/at-wksp-2015/session4/1-wilson-508.pdf

    Mechanisms of Acute Toxicity Dan Wilson, PhD, DABT Science Leader - Cheminformatics The Dow Chemical Company Acute Tox Workshop Sep 24, 2015 Acknowledgements . Barun Bhhatarai . Ed ...

  3. RoC Monograph: Cobalt and Cobalt Compounds; April 2016 3.5MB

    https://ntp.niehs.nih.gov/ntp/roc/monographs/cobalt_final_508.pdf

    Cobalt and Cobalt CoMpounds that Release Cobalt ions in ViVo ROC MONOGRAPH 06 APRIL 2016 Report on Carcinogens Monograph on Cobalt and Cobalt Compounds That Release Cobalt Ions In ...

  4. Public Comment: Cobalt and Certain Cobalt Compounds; Andrew Monnot... 491KB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/publiccomm/monnot20131018_508.pdf

    October 18, 2013 Dr. Ruth Lunn, Director, ORoC, DNTP NIEHS, P.O. Box 12233, MD K2-14 Research Triangle Park, NC 27709 lunn@niehs.nih.gov RE: Nominations to the Report on ...

  5. CERHR Monograph: Soy Infant Formula 122.6MB

    https://ntp.niehs.nih.gov/ntp/ohat/genistein-soy/soyformula/soymonograph2010_508.pdf

    National Toxicology Program U.S. Department of Health and Human Services C E R H R N T P Center for the Evaluation of Risks to Human Reproduction NIH Publication No. 10-5995 ...

  6. NTP Monograph: Identifying Research Needs for Assessing Safe... 1.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/folicacid/final_monograph_508.pdf

    NTP MONOGRAPH: IDENTIFYING RESEARCH NEEDS FOR ASSESSING SAFE USE OF HIGH INTAKES OF FOLIC ACID August 1, 2015 Office of Health Assessment and Translation Division of the National ...

  7. Public Comment: Ruth Danzeisen of Cobalt Development Institute... 1.1MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/publiccomm/cdi20150708.pdf

    the Cobalt Development Institute 8 July 2015 18 Jeffries Passage, Guildford, Surrey, GU1 4AP, United Kingdom Tel: +44 1483 578877 e-mail: info@thecdi.com Fax: +44 1483 567042 ...

  8. Comment: Meat-related exposures (OHAT1); Shalene McNeill, The... 67KB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/mcneill_1ohat20161007.pdf

    Boyd: The Beef Checkoff appreciates the opportunity to submit scientific evidence to the Office of Health Assessment and Translation (OHAT) in response to the September 9, 2016, ...

  9. TR-244: Polybrominated Biphenyl Mixture (Firemaster FF-1) in... 8.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr244.pdf

    4 CARClNOG EN ES IS STUDIES OF POLYBROMINATED BIPHENYL MIXTURE (FIREMASTER FF-1) (CAS NO. 67774-32-7) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND ...

  10. TR-581: Cobalt Metal (CASRN 7440-48-4) in F344/N Rats and B6C3F1... 9.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr581_508.pdf

    The Toxicology STudieS of cobalT MeTal (caSRN 7440-48-4) iN f344/N RaTS aNd b6c3f1/N Mice aNd Toxicology aNd caRciNogeNeSiS STudieS of cobalT MeTal iN f344/NTac RaTS aNd b6c3f1/N ...

  11. In silico and in vitro analysis of 4,4-methylenedianiline replacements 1.7MB

    https://ntp.niehs.nih.gov/iccvam/meetings/sot20/adams-iccvam-poster.pdf

    In silico and in vitro analysis of 4,4'-methylenedianiline replacements Valerie H. Adams 1,2 , Emily N. Reinke 2 , Lindsay A. Holden 2 , and John J. LaScala 3 1 presenting author, ...

  12. Literature Search Results: Systematic Review of Fluoride Exposure... 768KB

    https://ntp.niehs.nih.gov/ntp/ohat/fluoride/literature_results20200916_508.pdf

    LITERATURE SEARCH RESULTS FOR THE SYSTEMATIC REVIEW OF FLUORIDE EXPOSURE AND NEURODEVELOPMENTAL AND COGNITIVE HEALTH EFFECTS September 16, 2020 Office of Health Assessment and ...

  13. TOX-73: Diazoaminobenzene (CASRN 136-35-6) 2.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox073.pdf

    3 NTP Report on the Metabolism, Toxicity, and Predicted Carcinogenicity of Diazoaminobenzene (CAS No. 136-35-6) September 2002 U.S. Department of Health and Human Services Public ...

  14. ICCVAM Background Review Document (Vol 2): In Vitro Cytotoxicity... 61.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol2_nov2006.pdf

    Methods for Estimating Acute Oral Systemic Toxicity Background Review Document Volume 2 of 2 Prepared by The National Toxicology Program (NTP) Interagency Center for the Evaluation ...

  15. NTP Monograph on Health Effects of Low-Level Lead Appendices... 6.8MB

    https://ntp.niehs.nih.gov/ntp/ohat/lead/final/appendicesathrue_final_508.pdf

    APPENDICES A - E: HUMAN STUDIES CONSIDERED IN DEVELOPING CONCLUSIONS U.S. Department of Health and Human Services Office of Health Assessment and Translation Division of the ...

  16. RoC Profile: Cobalt-Related Exposures; 15th RoC 2021 409KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/cobalt.pdf

    Genomic stability Oxidative damage Hypoxia-responsive target genes Resistance to apoptosis Accumulation of critical mutations Dysregulation of cell growth and proliferation Tumor ...

  17. TR-217: Di(2-ethylhexyl)phthalate (CASRN 117-81-7) in F344 Rats... 5.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr217.pdf

    7 CARCINOGENESIS BIOASSAY OF DI(2-ETHYLHEXYL)PHTHALATE (CAS NO. 117-81-7) IN F344 RATS AND B6C3F] MICE (FEED STUDY) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health ...

  18. CERHR Monograph: Potential Human Reproductive and Developmental... 6.3MB

    https://ntp.niehs.nih.gov/ntp/ohat/bisphenol/bisphenol.pdf

    MoNogRaPH oN THE PoTENTial HuMaN REPRoduCTivE aNd dEvEloPMENTal EffECTs of BisPHENol a September 2008 NIH Publication No. 08 - 5994 Center for The Evaluation of Risks To Human ...

  19. Documents Provided to the NTP Board of Scientific Counselors... 55.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/fluoride/documents_provided_bsc_wg_031523.pdf

    DRAFT NTP Monograph on the State of the Science Concerning Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects: A Systematic Review NTP Monograph 08 September ...

  20. NTP Monograph on Health Effects of Low-Level Lead Appendix A... 2.5MB

    https://ntp.niehs.nih.gov/ntp/ohat/lead/final/leadappendixa_final_508.pdf

    APPENDIX A: HUMAN STUDIES OF NEUROLOGICAL EFFECTS OF LEAD CONSIDERED IN DEVELOPING CONCLUSIONS U.S. Department of Health and Human Services Office of Health Assessment and ...

  21. TR-288: 1,3-Butadiene (CASRN 106-99-0) in B6C3F1Mice (Inhalation... 5.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr288.pdf

    88 TOXICOLOGY AND CARCINOGENESIS STUDIES OF 1,S-BUTADIENE (CAS NO. 106-99-0) IN B6C3F1 MICE (INHALATION STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service ...

  22. DART-04: Prenatal Development Studies of Dimethylaminoethanol... 1006KB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart04_508.pdf

    DimeThylamiNoeThaNol BiTaRTRaTe (caSRN 5988-51-2) iN SPRague Dawley (hSD:SPRague Dawley ® SD ® ) RaTS (gavage STuDieS) NTP DART 04 JUNE 2020 NTP Developmental and Reproductive ...

  23. TR-597: 2-Hydroxy-4-methoxybenzophenone (CASRN 131-57-7) Administered... 3.2MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr597_508.pdf

    NTP TechNical RePoRT oN The Toxicology aNd caRciNogeNesis sTudies of 2-hydRoxy- 4-meThoxybeNzoPheNoNe (casRN 131-57-7) admiNisTeRed iN feed To sPRague dawley (hsd:sPRague dawley ® ...

  24. NTP Monograph on Health Effects of Low-Level Lead Appendix C... 1.2MB

    https://ntp.niehs.nih.gov/ntp/ohat/lead/final/leadappendixc_final_508.pdf

    C: HUMAN STUDIES OF CARDIOVASCULAR EFFECTS OF LEAD CONSIDERED IN DEVELOPING CONCLUSIONS Appendix C: Human Studies of Cardiovascular Effects of Pb Considered in Developing ...

  25. TR-603: Black Cohosh Root Extract (CASRN 84776-26-1) Administered... 3.1MB

    https://ntp.niehs.nih.gov/sites/default/files/2023-12/tr603_508.pdf

    NTP TechNical RePoRT oN The Toxicology aNd caRciNogeNesis sTudies of Black cohosh RooT exTRacT (casRN 84776-26-1) admiNisTeRed By gavage To sPRague dawley (hsd:sPRague dawley ® sd ...

  26. TR-326: Ethylene Oxide (CASRN 75-21-8) in B6C3F1Mice (Inhalation... 6.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr326.pdf

    6 TOXICOLOGY AND CARCINOGENESIS STUDIES O F ETHYLENE OXIDE (CAS NO. 75-21-8) IN B6C3F1 MIiCE (INHALATION STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service ...

  27. TOX-81: α-Pinene (CASRN 80-56-8) Administered by Inhalation... 2.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox081_508.pdf

    STudieS of α-PiNeNe (caSRN 80-56-8) admiNiSTeRed by iNhalaTioN f344/N RaTS aNd b6c3f1/N mice To NTP TOX 81 MAY 2016 NTP Technical Report on the Toxicity Studies of α-Pinene (CAS ...

  28. Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf

    The Murine Local Lymph Node Assay: A Test Method for Assessing the Allergic Contact Dermatitis Potential of Chemicals/Compounds The Results of an Independent Peer Review Evaluation ...

  29. TR-361: Hexachloroethane (CASRN 67-72-1) in F344/N Rats (Gavage... 7.2MB

    https://ntp.niehs.nih.gov/go/tr361

    61 {* / &' , $ W ' . , . * > J * . , , TOXICOLOGY AND CARCINOGENESIS STUDIES OF HEXACHLOROETHANE (CAS NO. 67-72-1) IN F344/N RATS (GAVAGE STUDIES) U.S. DEPARTMENT O F HEALTH AND H ...

  30. TR-274: Tris(2-ethylhexyl)phosphate (CASRN 78-42-2) In F344/N... 8.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr274.pdf

    4 TOXICOLOGY AND CARCINOGENESIS STUDIES OF TRIS(2-ETHYLHEXYL)PHOSPHATE (CASNO. 78-42-2) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES ...

  31. TR-359: 8-Methoxypsoralen (CASRN 298-81-7) in F344/N Rats (Gavage... 7.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr359.pdf

    NQ. 359 TOXICOLOGY AND CARCINOGENESIS STUDIES OF 8-METHOXYPSORALEN (CAS NO. 298-81-7) IN F344/N RATS (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health ...

  32. Application of Non-animal Test Methods and Defined Approaches... 22.2MB

    https://ntp.niehs.nih.gov/iccvam/methods/immunotox/it/niceatm-it-report-june2020-final-wappx-508.pdf

    Application of Non-animal Test Methods and Defined Approaches to Skin Sensitization Assessment of Isothiazolinone Compounds Application of Non-animal Test Methods and Defined ...

  33. DART-03: Prenatal Development Studies of Vinpocetine (CASRN 42971... 1.2MB

    https://ntp.niehs.nih.gov/ntp/htdocs/dart/dart03_508.pdf

    viNPoceTiNe (caSRN 42971-09-5) iN SPRague Dawley (hSD:SPRague Dawley ® SD ® ) RaTS aND New ZealaND whiTe (hRa:NZw SPf) RabbiTS (gavage STuDieS) NTP DART 03 JUNE 2020 NTP ...

  34. TR-294: Chlorinated Trisodium Phosphate (CASRN 56802-99-4) in... 6.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr294.pdf

    National Toxicology Program Technical Report Series No. 294 TOXICOLOGY AND CARCINOGENESIS STUDIES OF CHLORINATED TRISODIUM PHOSPHATE (CAS NO. 56802-99-4) IN B6C3F1 MICE (GAVAGE ...

  35. TR-325: Pentachloronitrobenzene (CASRN 82-68-8) in B6C3F1Mice... 6.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr325.pdf

    5 TOXICOLOGY AND CARCINOGENESIS STUDIES OF PENTACHLORONITROBENZENE (CAS NO. 82-68-8) IN B6C3F1 MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health ...

  36. TR-381: d-Carvone (CASRN 2244-16-8) in B6C3F1Mice (Gavage Studies... 6.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr381.pdf

    1 TOXICOLOGY AND CARCINOGENESIS STUDIES OF d-CARVONE (CAS NO. 2244-16-8) IN B6C3F1 MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service National ...

  37. TR-334: 2-Amino-5-Nitrophenol (CASRN 121-88-0) in F344/N Rats... 9.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr334.pdf

    PROGRAM Technical Report Series No. 334 TOXICOLOGY AND CARCINOGENESIS STUDIES OF 2-AMINO-5-NITROPHENOL (CAS NO. 121-88-0) IN F344/N RATS AND B6C3Fi MICE (GAVAGE STUDIES) U.S. ...

  38. TR-347: d-Limonene (CASRN 5989-27-5) in F344/N Rats and B6C3F1Mice... 9.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr347.pdf

    7 4 "^,oC C Z» TOXICOLOGY ANDCARCINOGENESIS STUDIES OF d-LIMONENE (CAS NO. 5989-27-5) IN F344/N RATS AND B6C3Fi MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES ...

  39. TR-444: Initiation/Promotion Study of o-Benzyl-p-Chlorophenol... 6.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr444.pdf

    NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 444 ONE-YEAR INITIATION/PROMOTION STUDY OF O-BENZYL-p-CHLOROPHENOL (CAS NO. 120-32-1) IN SWISS (CD-l@) MICE (MOUSE SKIN ...

  40. TR-281: HC Red No. 3 [2,((Amino-2-nitrophenyl)amino)ethanol]... 8.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr281.pdf

    1 TOXICOLOGY AND CARCINOGENESIS STUDIES OF HC RED NO. 3 [2,-((4-AMINO-2-NITROPHENY L)AMINO)ETHANOLl (CAS NO. 2871-01-4) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. ...

  41. TR-311: Tetrachloroethylene (Perchloroethylene) (CASRN 127-18... 13.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr311.pdf

    PROGRAM Technical Report Series No. 311 X J """''V TOXICOLOGY AND CARCINOGENESIS STUDIES OF TETRACHLOROETHYLENE (PERCHLOROETHYLENE) (CAS NO. 127-18-4) IN F344/N RATS AND B6C3Fi ...

  42. TR-368: Nalidixic Acid (CASRN 389-08-2) in F344/N Rats and B6C3F1Mice... 13.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr368.pdf

    PROGRAM Technical Report Series No. 368 *<»vdia TOXICOLOGY AND CARCINOGENESIS STUDIES OF NALIDIXIC ACID (CAS NO. 389-08-2) IN F344/N RATS AND B6C3Fi MICE (FEED STUDIES) U.S. ...

  43. TR-370: Benzofuran (CASRN 271-89-6) in F344/N Rats and B6C3F1Mice... 12.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr370.pdf

    70 TOXICOLOGY AND CARCINOGENESIS STUDIES OF BENZOFURAN (CAS NO. 271-89-6) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health ...

  44. TR-456: 1,2-Dihydro-2,2,4-Trimethylquinoline (CASRN 147-47-7... 17.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr456.pdf

    FOREWORD The National Toxicology Program (NTP) is made up of four charter agencies of the U.S. Department of Health a:nd Human Services (DHHS): the National Cancer Institute (NCI), ...

  45. TOX-83: Toxicity Studies of o-Chloropyridine (CASRN 109-09-1... 3.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox83_508.pdf

    oN The ToxiciTy STudieS of o-chloRoPyRidiNe (caSRN 109-09-1) admiNiSTeRed deRmally aNd iN dRiNkiNg WaTeR To f344/N RaTS aNd B6c3f1/N mice NTP TOX 83 FEBRUARY 2017 NTP Technical ...

  46. Recommended Performance Standards for the LLNA 2.2MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf

    Recommended Performance Standards: Murine Local Lymph Node Assay Interagency Coordinating Committee on the Validation of Alternative Methods National Toxicology Program ...

  47. TR-337: Nitrofurazone (CASRN 59-87-0) in F344/N Rats and B6C3F1Mice... 10.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr337.pdf

    7 TOXICOLOGY AND CARCINOGENESIS STUDIES OF NITROFURAZONE (CAS NO. 59-87-0) IN F344/N RATS AND B6C3F1 MICE (FEED STUDIES) U.S. DEPARTMENT O F HEALTH AND HUMAN SERVICES Public Health ...

  48. TR-343: Benzyl Alcohol (CASRN 100-51-6) in F344/N Rats and B6C3F1Mice... 8.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr343.pdf

    3 TOXICOLOGY AND CARCINOGENESIS STUDIES OF BENZYL ALCOHOL (CAS NO. 100-51-6) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public ...

  49. Draft RoC Monograph Cobalt: RoC Peer Review; July 22, 2015 2.8MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_draftmonograph.pdf

    Cobalt and Certain Cobalt Compounds June 5, 2015 Office of the Report on Carcinogens Division of the National Toxicology Program National Institute of Environmental Health ...

  50. TR-300: 3-Chloro-2-methylpropene (Technical grade containing... 10.1MB

    https://ntp.niehs.nih.gov/go/tr300

    0 TOXICOLOGY A N D CARCINOGENESIS STUDIES OF 3-CHLORO-2-METHYLPROPENE (Technical grade containing 5% dimethylvinyl chloride) (CAS NO. 563-47-3) IN F344/N RATS AND B6C3F1 MICE ...

 
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