-
Abstract for TR-552 73KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr552
Propargyl alcohol is a commercially available acetylenic primary alcohol. It is also a by-product in the industrial synthesis of butynediol from acetylene and formaldehyde with ...
-
Abstract for TR-2 62KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr002
CASRN: 79-01-6 Chemical Formula: C2HCl3 Molecular Weight: 131.40 Synonyms/Common Names: trichloroethene; acetylene trichloride; ethinyl trichloride; 1,1,2-trichloroethylene, TCE ...
-
Abstract for TR-27 59KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr027
CASRN: 79-34-5 Chemical Formula: C2H2Cl4 Molecular Weight: 167.85 Synonyms/Common Names: acetylene tetrachloride; sym-tetrachloroethane Report Date: 1978 Full Report PDF Abstract ...
-
Abstract for RoC MGRAPH-05 59KB
https://ntp.niehs.nih.gov/publications/roc/rocmgraph05
CASRN: 79-01-6 Chemical Formula: C2HCl3 Molecular Weight: 131.4 Synonyms/Common Names: TCE; TRI; 1,1,2-trichloroethylene; trichloroethene; ethylene trichloride; acetylene ...
-
Abstract for TOX-55 60KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox055
CASRN: 156-60-5 Chemical Formula: C2H2Cl2 Molecular Weight: 96.95 Synonyms/Common Names: Trans-acetylene dichloride; (E)-1,2-dichloroethene; (E)-(9Cl)-1,2-dichloroethene; ...
-
Abstract for TR-273 63KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr273
CASRN: 79-01-6 Chemical Formula: C2HCl3 Molecular Weight: 131.4 Synonyms/Common Names: Acetylene trichloride; 1-chloro-2,2-dichloroethylene; 1,1-dichloro-2-chloroethylene; ethinyl ...
-
Abstract for TOX-49 65KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox049
CASRN: 79-34-5 Chemical Formula: C2H2CL4 Molecular Weight: 167.86 Synonyms/Common Names: Acetylene tetrachloride; 1,1-dichloro-2,2-dichloroethane; sym-tetrachloroethane; TCE; ...
-
RoC Background Document: Chloroprene; Oct. 30-31, 1997 5.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/newhomeroc/other_background/chloroprene1_508be.pdf
... acid to dimerized acetylene (Johnson, 1979a; IARC, 1979a; NTP, 1998). 1,3- Butadiene chlorination became more economical about 1965 as the price of acetylene increased and that ...
-
TR-552: Toxicology and Carcinogenesis Studies of Propargyl Alcohol... 1.4MB
https://ntp.niehs.nih.gov/go/tr552
... It is also a by-product in the industrial synthesis of butynediol from acetylene and ... alcohol that can be prepared from acetylene by high-pressure synthesis (Lewis, 1993). ...
-
RoC Concept: Trichloroethylene 729KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/thirteenth/concepts/tce_revised_concdocroc12-31-13_508.pdf
... commercially since the 1920s in many countries by chlorination of ethylene or acetylene. ... 79-01-6, TCE, trichloroethene, acetylene trichloride, ethylene trichloride] ...
-
Protocol: Methods for preparing the RoC Monograph: TCE 1.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/thirteenth/protocols/tce_final20140625_508.pdf
... OR TCE) OR trichloroethene) OR "acetylene trichloride") OR "ethylene ... 79-01-6, TCE, trichloroethene, acetylene trichloride, ethylene trichloride] TCE ...
-
RoC Profile: Tetranitromethane; 15th RoC 2021 125KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/tetranitromethane.pdf
... By the end of the war, a less expensive method using acetylene and nitric acid was de- vised, with a reported production capacity of 10 kg/day (NTP 1990). No current estimates of ...
-
Protocol: Methods for preparing the draft RoC Monograph: TCE 1.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/thirteenth/protocols/tce_protocol12-31-13_508.pdf
... OR TCE) OR trichloroethene) OR "acetylene trichloride") OR "ethylene ... 79-01-6, TCE, trichloroethene, acetylene trichloride, ethylene trichloride] TCE ...
-
RoC Profile: Coke-Oven Emissions; 15th RoC 2021 119KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/cokeovenemissions.pdf
... Coke-oven gas includes hydrogen, methane, ethane, carbon monoxide, carbon diox- ide, ethylene, propylene, butylene, acetylene, hydrogen sulfide, am- monia, oxygen, and nitrogen. ...
-
TR-273: Trichloroethylene (CASRN 79-01-6) in Four Strains of... 16.9MB
https://ntp.niehs.nih.gov/go/tr273
... C2HC13 Molecular weight 131.4 Synonyms: Acetylene trichloride; l-chloro-2,2-dichloroethyle... C2HC13 Molecular weight 131.4 Synonyms: Acetylene trichloride; l-chloro-2,2-dichloroethyle...
-
TOX-55: Toxicity Studies of trans-1,2-Dichloroethylene (CASRN... 1.7MB
https://ntp.niehs.nih.gov/go/tox055
... Molecular Weight: 96.95 Synonyms: trans-Acetylene dichloride; (E)-1,2-dichloroethene; ... synthesized by direct chlorination of acetylene at 40° C, by dehydrochlorination of ...
-
TR-002: Trichloroethylene (CASRN 79-01-6) 19.9MB
https://ntp.niehs.nih.gov/go/tr002
... and Common Name: Trichloroethylene Acetylene trichloride Ethinyl trichloride ... a highly toxic precursor in the acetylene-based manufacturing process, but current ...
-
RoC Profile: Beryllium and Beryllium Compounds; 15th RoC 2021 149KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/berylliumandberylliumcompounds.pdf
... for the production of beryllium oxide powder for ce- ramics, and beryllium nitrate is used as a chemical reagent and for stiffening mantles in gas and acetylene lamps (HSDB 2009). ...
-
TOX-41: Toxicity Studies of 1,1,1-Trichloroethane (CASRN 76-55... 1.2MB
https://ntp.niehs.nih.gov/go/tox041
... Metabolism of 1,1,1-trichloroethane to acetylene by hepatic cytochrome P450 in rats has ... Assoc. 50, 1096-1121. Dürk, H., Poyer, J.L., Klessen, C., and Frank, H. (1992). Acetylene...
-
TOX-54: 1,4-Butanediol (CASRN 110-63-4) 577KB
https://ntp.niehs.nih.gov/go/tox054
... PRODUCTION, USE, AND HUMAN EXPOSURE Industrial synthesis of 1,4-butanediol is accomplished in three steps. In the first step, formaldehyde and acetylene are condensed in the ...
-
TOX-3: Acetone (CASRN 67-64-1) 2.6MB
https://ntp.niehs.nih.gov/go/tox003
... et al., 1978, 1982), acetylene (Foley, 1985), or disulfiram (DeMaster and Nagasawa, 1977). ... 210-211. 29. Foley, R.J. (1985) I n h a l e d i n d u s t r i a l acetylene. J. Am. Med. ...
-
TOX-49: Toxicity Studies of 1,1,2,2-Tetrachloroethane (CASRN... 1.2MB
https://ntp.niehs.nih.gov/go/tox049
... CAS No. 79-34-5 Chemical Formula: C 2 H 2 Cl 4 Molecular Weight: 167.86 Synonyms: Acetylene tetrachloride; 1,1-dichloro-2,2-dichloroethane; sym-tetrachloroethane; TCE; ...
-
TR-027: 1,1,2,2-Tetrachloroethane (CASRN 79-34-5) 3.0MB
https://ntp.niehs.nih.gov/go/tr027
... The Chemical Abstracts Service (CAS) Ninth Collective Index (1977) name for this compound is 1,1,2,2-tetrachloroethane. It is also called acetylene tetrachloride or ...
-
RoC Background Document: Trichloroethylene (TCE); Oct. 30-31... 3.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/newhomeroc/other_background/trichl_tce1997_2apps_508.pdf
... Ethene, trichloro- (9CI) Flock flip Trichloran Ethylene, trichloro- (SCI) Fluate Trichloren Acetylene trichloride Gemalgene Trichlorethylene Algylen Germalgen Trichloroethene ...
-
RoC Background Document: Vinyl Fluoride; Jan. 20-21, 2000 468KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/newhomeroc/roc10/vf_no_appendices_508.pdf
... VF was first prepared in the early 1900s by a reaction of zinc with 1,1- difluoro-2-bromoethane . Modern preparation of VF involves a reaction of acetylene and hydrogen fluoride in ...
-
TOX-22: N,N-Dimethylformamide (CASRN 68-12-2) 1.9MB
https://ntp.niehs.nih.gov/go/tox022
... DMF is used in many hydrocarbon separations, such as the recovery or removal of acetylene and the extraction of butadiene from hydrocarbon streams (DuPont, 1980; Sax and Lewis, ...
-
RoC Background Document: Vinyl Bromide; Jan. 20-21, 2000 220KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/newhomeroc/roc10/vb_no_appendices_508.pdf
... Hydroquinone methyl ether (0.02%, used as stabilizer), ethylene oxide (0.03%), acetylene (0.0007%), and aldehydes and ketones (0.008%) were present in the VB used. The animals in ...
-
RoC Monograph: Trichloroethylene; January 2015 4.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/monographs/finaltce_508.pdf
... 79-01-6 Molecular formula C 2 HCl 3 Synonyms TCE; TRI; 1,1,2-trichloroethylene; trichloroethene; ethylene trichloride; acetylene trichloride Source: HSDB (2012), IARC (2014). ...
-
RoC Profile: Vinyl Halides (Selected); 15th RoC 2021 199KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/vinylhalides.pdf
... Vinyl fluoride was first prepared in the early 1900s by reaction of zinc with 1,1-difluoro-2-bromoethane. Modern preparation of vi- nyl fluoride involves reaction of acetylene and ...
-
TR-386: Tetranitromethane (CASRN 509-14-8) in F344/N Rats and... 12.9MB
https://ntp.niehs.nih.gov/go/tr386
... By the end of the war, however, a less costly method using acetylene and nitrie acid, with a reported capacity of 10 kglday, was in use. E x p o s u r e Current estimates of ...
-
TR-467: Chloroprene (CASRN 126-99-8) in F344/N Rats and B6C3F1Mice... 14.5MB
https://ntp.niehs.nih.gov/go/tr467
... PRODUCTION, USE, AND HUMAN EXPOSURE Chloroprene is produced by the addition of hydro- chloric acid to dimerized acetylene or by the chlo- rination of 1,3-butadiene (IARC, 1979; ...
-
RoC Background Document: Diesel Exhaust Particulates; Dec. 2... 5.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/newhomeroc/other_background/dieselexhaust_508.pdf
... 1989) acetone (Volkswagen 1989) acetylene (Volkswagen 1989) acrolein (ARB 1993; ... Environ. int., 5, 485-488 Whitby, R.A. & Altwicker, E.R. (1978) Acetylene in the ...
-
TR-289: Benzene (CASRN 71-43-2) in F344/N Rats and B6C3F1Mice... 16.4MB
https://ntp.niehs.nih.gov/go/tr289
... The commercial recovery of benzene from this source was developed and described by Mans- field in 1849. The synthesis of benzene by the polymerization of acetylene was first ...
-
TR-238: Ziram (CASRN 137-30-4) in F344/N Rats and B6C3F1Mice... 11.2MB
https://ntp.niehs.nih.gov/go/tr238
... vehicle analyses were performed.) Slit width: 0.2 nm Flame: Air/ acetylene Gas flows: Air, 30 psi Acetylene, 12 psi Background correction: Hydrogen lamp Results: See Table GI * ...
-
TR-421: Talc (CASRN 14807-96-6)(Non-Asbestiform) in F344/N Rats... 16.3MB
https://ntp.niehs.nih.gov/go/tr421
... hollow cathode lamp and an air acetylene flame (Hanson et QZ., 195). 206 Talc, ... with a magnesium hollow cathode lamp and an air acetylene flame (Hanson et al., 1985). ...
-
TR-231: Stannous Chloride (CASRN 7772-99-8) in F344/N Rats and... 8.4MB
https://ntp.niehs.nih.gov/go/tr231
... 224.6 nm Slit Width: 0.2 nm Flame: Nitrous oxide/ acetylene Background correction: Hydrogen lamp Plain feed and spiked-plain feed samples were analyzed under the same conditions. ...