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Abstract for TR-432 63KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr432
Barium chloride dihydrate, a white crystalline granule or powder, is used in pigments, aluminum refining, leather tanning and coloring, the manufacture of magnesium metal, ...
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Abstract for TR-586 71KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr586
CIMSTAR 3800 is used in the general machining and grinding of automotive aluminum parts and on light to moderate machining and grinding of light steel, stainless steels, hardened ...
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RoC Profile: Hexachloroethane; 15th RoC 2021 145KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/hexachloroethane.pdf
In a cohort study of workers at aluminum found- ries and smelters in Sweden, no ... and with metals such as zinc, cadmium, aluminum, hot iron, and mercury (NIOSH 2005). ...
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RoC Profile: Coal Tars and Coal-Tar Pitches; 15th RoC 2021 132KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/coaltars.pdf
of workers exposed to pitch fumes in aluminum production and calcium carbide ... tars and coal-tar pitches and in aluminum production workers exposed to coal-tar pitches. ...
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TOX-74: Toxicity Study Report on the Atmospheric Characterization... 6.9MB
https://ntp.niehs.nih.gov/go/tox074
... components (>0.1% by weight) included aluminum, boron, calcium, sodium, and sulfur. An ... was found to consist primarily of aluminum silicate hydroxide (kaolinite; ~85%) ...
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RoC Profile: Beryllium and Beryllium Compounds; 15th RoC 2021 149KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/berylliumandberylliumcompounds.pdf
Beryllium metal and several be- ryllium compounds, including beryllium-aluminum alloy, ... Beryllium is lighter than aluminum, but it is over 40% more rigid and approximately ...
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Abstract for TOX-74 60KB
https://ntp.niehs.nih.gov/publications/reports/tox/tox074
components (>0.1% by weight) included aluminum, boron, calcium, sodium, and sulfur. An ... was found to consist primarily of aluminum silicate hydroxide (kaolinite; ~85%) ...
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TR-586: Lay Summary; CIMSTAR 3800 179KB
https://ntp.niehs.nih.gov/sites/default/files/2025-02/tr586_summary_508.pdf
SUMMARY Background: CIMSTAR® 3800 is a metalworking fluid used as a lubricant and for cooling during the machining and grinding of aluminum and steel. Exposure to CIMSTAR 3800 ...
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TOX-77: Lay Summary; Hexachlorobenzene (CASRN 118-74-1) 191KB
https://ntp.niehs.nih.gov/sites/default/files/2025-03/tox077_summary_508.pdf
SUMMARY Background: Hexachlorobenzene (HCB) was used in the United States as a fungicide and wood preserving agent as well as in the manufacture of aluminum and rubber until it was ...
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Bone - Increased Osteoid - Nonneoplastic Lesion Atlas 282KB
https://ntp.niehs.nih.gov/atlas/nnl/musculoskeletal-system/bone/IncreasedOsteoid
Increased osteoid has been induced in rats by various compounds that inhibit mineralization of osteoid, including bisphosphonates, aluminum, cadmium, phosphorus deficiency, and ...
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RoC References: Antimony and Other Antimony Compounds; Aug. 17... 599KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/references/antimonyreferences_508.pdf
... G. 1988. Compensating bladder cancer victims employed in aluminum reduction plants. ... the incidence of cancer in a cohort of workers at a primary aluminum smelter in Sweden. ...
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Bone - Increased Osteoid 477KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/musculoskeletal/bone/incost/bone-increased-osteoid-pdf_508.pdf
Increased osteoid has been induced in rats by various compounds that inhibit mineralization of osteoid, including bisphosphonates, aluminum, cadmium, phosphorus deficiency, and ...
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RoC Background Document: Beryllium Compounds; Dec. 16-17, 1999 5.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/newhomeroc/roc10/be_no_appendices_508.pdf
... review include the following: beryllium-aluminum alloy beryllium-copper alloy ... Beryllium is lighter than aluminum but is > 40% more rigid than steel. Beryllium's modulus ...
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15th RoC: Appendix A 49KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/appendix_a.pdf
Acheson process, occupational exposure associated with (synthesis of silicon carbide) (IARC 2017) . Aluminum production, occupational exposures during (IARC 2012b) . Auramine ...
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15th RoC: Appendix F 165KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/appendix_f.pdf
see Ionizing Radiation, Radon alcohol drinking see Alcoholic Beverage Consumption aluminum-beryllium alloy see Beryllium and Beryllium Compounds o-aminoanisole see o-Anisidine ...
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RoC Background Document: Metallic Nickel and Certain Nickel Alloys... 1.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/newhomeroc/roc10/ni_no_appendices_508.pdf
... the following: ferronickel nickel-aluminum alloys nickel-containing steels ... Fe, Ni Nickel- aluminum alloys 61431-86-5 37187-84-1 WI6800000 Ranel alloy, Raney nickel ...
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Appendices A-G; 15th RoC 2021 433KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/appendices_508.pdf
Aluminum production, occupational exposures during (IARC 2012b) . Auramine production ... see Alcoholic Beverage Consumption aluminum-beryllium alloy see Beryllium and ...
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Literature Search Results: Systematic Review of Fluoride Exposure... 743KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/fluoride/literature_results20200916_508.pdf
... Effects of fluoride on psychomotor performance and memory of aluminum potroom workers. ... caused by fluorine and aluminum exposure during the embryonic stage and into adulthood. ...
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TR-432: Barium Chloride Dihydrate (CASRN 10326-27-9) in F344... 15.3MB
https://ntp.niehs.nih.gov/go/tr432
... granule or powder, is used in pigments, aluminum refining, leathertanningand coloring, ... powder chloride is used in aluminum refining, leather tanning with a bitter salty taste. ...
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Public Comment: David J. Wawer; Color Pigments Manufacturers... 217KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2015/july/publiccomm/wawer20160106.pdf
... and the pigment identified as Cobalt Aluminum Chrome Spinel in an intratracheal ... on Cobalt Oxide, but not for its conclusions regarding Cobalt Aluminum Chrome Spinel. ...
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Abstract for RR-11 55KB
https://ntp.niehs.nih.gov/publications/reports/rr/rr11
Elemental analysis by inductively coupled plasma with atomic emission spectrometry or mass spectrometry (MS) identified zinc, aluminum, cobalt, and other metals and metalloids ...
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Agency Response to ICCVAM Recommendations on In Vitro Ocular... 638KB
https://ntp.niehs.nih.gov/iccvam/methods/ocutox/ivocutox/transmit/dotresponse.pdf
a specified period of time." "A liquid that has a severe corrosion rate on steel or aluminum based on the criteria in 49 CFR 173.l37(c)(2) is also a corrosive material" (49 CFR ...
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RoC Background Document for Naphthalene; Sept. 19, 2002 4.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/newhomeroc/roc11/naphthalenepub_508.pdf
... makers, tannery workers, textile chemical workers, and aluminum reduction plant workers. ... makers, tannery workers, textile chemical workers, and aluminum reduction plant workers. ...
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NTP RR-11: The Chemical and Physical Characterization of Recycled... 2.1MB
https://ntp.niehs.nih.gov/go/rr11
... zinc, aluminum, cobalt, and other metals and metalloids totaling ~2.9% by weight. ... 9000 (PerkinElmer, Waltham, MA) and for aluminum, cobalt, chromium, copper, iron, ...
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CERHR Monograph: Soy Infant Formula 122.6MB
https://ntp.niehs.nih.gov/go/soy_monograph
... Aluminum from mineral salts is found in soy infant formulas at concentrations of 600 - 1300 ng/mL, levels that exceed aluminum concentrations in human milk, 4 - 65 ng/mL (Bhatia ...
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RoC Background Document for Lead and Lead Compounds - May 8,... 3.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/newhomeroc/roc11/lead-public_508.pdf
... In worldwide metal use, lead ranks behind only iron, copper, aluminum, and zinc. Its ... worldwide metal use, lead ranks behind only iron, copper, aluminum, and zinc (Howe 1981). ...
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Public Comment: Cobalt and Certain Cobalt Compounds; Andrew Monnot... 491KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/thirteenth/publiccomm/monnot20131018_508.pdf
The primary uses of Co metal are: (1) high temperature, corrosion-resistant superalloys (e.g., used in turbine aircraft engines); (2) magnetic alloys with aluminum, copper, nickel ...
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RoC Profile: Cupferron; 15th RoC 2021 165KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/cupferron.pdf
In analytical laboratories, cupferron is a reagent used for quantitative determination of vana- dates and titanium and the colorimetric determination of aluminum (NCI 1978, HSDB ...
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Protocol for Systematic Review of Effects of Fluoride Exposure... 1.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/ohat/fluoride/protocol_fluoridemay2019_508.pdf
... Other forms of fluoride that readily dissociate into free fluoride ions (e.g., potassium fluoride, calcium fluoride, ammonium fluoride) . REVISION: Aluminum fluoride or aluminum ...
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Background Document: RoC: Glass Wool Fibers; 2010 3.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/2010/finalbds/glasswoolbd20100408_508.pdf
... These modifiers include oxides of aluminum, titanium, zinc, magnesium, lithium, barium, ... inorganic fibrous materials that contain aluminum or calcium silicates, and are made from ...
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Developmental Neurotoxicity Screening Assay Chemical List | National... 411KB
https://www.niehs.nih.gov/research/atniehs/dtt/strategic-plan/health/developmental/chemical-list
... (KIH-485) Herbicide 78-48-8 DTXSID1024174 Tribufos Herbicide 31142-56-0 DTXSID3030711 Aluminum citrate Industrial 95-16-9 DTXSID7024586 Benzothiazole Industrial 85-68-7 ...
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NTP Protocol: Systematic Review of Effects of Fluoride Exposure... 2.1MB
https://ntp.niehs.nih.gov/ntp/ohat/fluoride/ntpprotocol_revised20200916_508.pdf
... Other forms of fluoride that readily dissociate into free fluoride ions (e.g., potassium fluoride, calcium fluoride, ammonium fluoride) . REVISION: Aluminum fluoride or aluminum ...
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Documents Provided to the NTP Board of Scientific Counselors... 55.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/fluoride/documents_provided_bsc_wg_031523.pdf
... In aluminum factory workers (exposed to gaseous and particular fluoride emissions during the production of aluminum metal), significant decreases in IQ (Duan et al. 1995), ...
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RoC Profile: Basic Red 9 Monohydrochloride; 15th RoC 2021 121KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/basicred9.pdf
... automobile antifreeze solutions, anodized aluminum, high-speed photoduplicating inks, photo-imaging systems, and ink- jet computer printers (NTP 1986, IARC 1993, HSDB 2009). ...
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TOX-75: Toxicity Studies of Dimethylaminopropyl Chloride, Hydrochlorid... 722KB
https://ntp.niehs.nih.gov/go/tox075
... with Teflon ® -lined butyl rubber stoppers and crimped aluminum caps for up to 35 days. ... sealed with Teflon ® -lined septa and aluminum caps, at refrigerated (5° C) and ...
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TR-100: Cupferron (CASRN 135-20-6) 3.9MB
https://ntp.niehs.nih.gov/go/tr100
... vanadates and titanium and for the colori- metric estimation of aluminum (Windholz, 1976). ... The compound was hand-blended in an aluminum bowl with an aliquot of the ground feed. Once ...
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RoC Background Document: Nickel Compounds; Dec. 2-3, 1998 6.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/newhomeroc/other_background/nickelcompds1_oneapp_508.pdf
... E ( ( Contains hydrogen and residual aluminum. Ignites spontaneously in air. Remains ... of other nickel compounds, a sealer for anodized aluminum, and in nickel electroplating. ...
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TR-492: Toxicology and Carcinogenesis Studies of Gallium Arsenide... 12.1MB
https://ntp.niehs.nih.gov/go/tr492
... extraction of Molecular Weight: 144.64 aluminum and zinc from their ores (Patty«s, 1994). ... the principal impurities were aluminum (52 ppm), silicon (33 ppm), and calcium (14 ppm). ...
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RoC Background Document: Vinyl Fluoride; Jan. 20-21, 2000 468KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/newhomeroc/roc10/vf_no_appendices_508.pdf
... Polyvinyl fluoride is laminated with aluminum, galvanized steel, and cellulosic materials ... hydrogen fluoride in the presence of a mercury- or aluminum-based catalyst (IARC 1995). ...
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RoC Profile: Asbestos; 15th RoC 2021 151KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/asbestos.pdf
... The hydroxyl group may, rarely, be replaced by oxygen, fluorine, or chlorine. In addition, small amounts of iron, aluminum, nickel, calcium, chromium, manganese, sodium, or ...
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TR-117: 6-Nitrobenzimidazole (CASRN 94-52-0) 4.2MB
https://ntp.niehs.nih.gov/go/tr117
... The compound was blended in an aluminum bowl with an aliquot of the feed. Once visual ... Control animals had untreated meal available. Alpine aluminum feed cups (Curtin Matheson ...
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TR-149: N,N'-Diethylthiourea (CASRN 105-55-5) 3.1MB
https://ntp.niehs.nih.gov/go/tr149
... of ferrous metals and aluminum alloys in brine (Hawley, 1971; Rose and Rose, 1966). ... cages (Lab Pro- ducts, Inc., Garfield, New Jersey) suspended from aluminum racks. ...
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Usefulness and Limitations of the LLNA for Potency Categorization... 25.3MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-pot/tmer.pdf
... of Substances 1 Inorganic chemicals 11 Aluminum compounds 1 Chromium compounds 1 ... # of Substances 2 Inorganic chemicals 11 Aluminum compounds 1 Chromium compounds 1 ...
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RoC Profile: Mineral Oils: Untreated and Mildly Treated; 15th... 124KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/mineraloils.pdf
... parts, and transform- ers, as well as workers employed in brass and aluminum produc- tion, engine repair, copper mining, and newspaper and commercial printing (IARC 1984). ...
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TOX-92: Toxicity Studies of Octahydro-tetramethyl-naphthalenyl... 4.2MB
https://ntp.niehs.nih.gov/go/tox092
... pentene-2-one in the presence of aluminum chloride to give a monocyclic ... with Teflon ® silicone septa and an aluminum crimp seal under a nitrogen headspace at ...
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TOX-102: Trans-resveratrol Administered by Gavage for Two Weeks... 2.6MB
https://ntp.niehs.nih.gov/go/tox102
... plants, which can be induced to produce greater quantities by applying aluminum chloride or aluminum sulfate to grape shoots and vines. 18; 19 Production of RES in harvested ...
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TR-064: 1-Nitronaphthalene (CASRN 86-57-7) 3.8MB
https://ntp.niehs.nih.gov/go/tr064
... The compound was hand blended in an aluminum bowl with an aliquot of the ground feed. Once ... The food, replenished daily, (R) was supplied in Alpine aluminum feed cups (Curtin ...
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TR-092: Hydrazobenzene (CASRN 122-66-7) 4.2MB
https://ntp.niehs.nih.gov/go/tr092
... dosage preparation, and hand-blended in an aluminum bowl with an aliquot of ground feed. ... Control animals had untreated meal ® available. Alpine aluminum feed cups (Curtin ...
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TR-114: 2,3,5,6-Tetrachloro-4-nitroanisole (CASRN 2438-88-2) 3.7MB
https://ntp.niehs.nih.gov/go/tr114
... The compound was blended in an aluminum bowl with an aliquot of the ground feed. Once ... Control animals received un- ® treated meal. Food was supplied to rats in Alpine aluminum ...
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TR-130: Aniline Hydrochloride (CASRN 142-04-1) 3.8MB
https://ntp.niehs.nih.gov/go/tr130
... The compound was hand-blended in an aluminum bowl with an aliquot of the ground feed. Once ... Alpine aluminum feed cups (Cirtin Matheson Scientific, Inc., Woburn, Massachusetts). For ...