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Search suggestions for "7440-22-4".

  1. CEBS Data Related to Nanoscale Silver (7440-22-4) https://cebs.niehs.nih.gov/cebs/test_article/7440-22-4


263 results found for "7440-22-4".

  1. Abstract for TER20001 63KB

    https://ntp.niehs.nih.gov/publications/abstracts/dev/ter20001

    Abstract for TER20001 Developmental Toxicity Evaluation for Silver Acetate Administered by ... The EPA Office of Solid Waste and Emergency Response (OSWER) nominated silver for ...

  2. Minutes: BSC; June 22, 2007 162KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2007/june/bsc_mins2007june22_508.pdf

    ......... 11 1. Nanoscale Silver ......more input on the future study of the nomination. 1. Nanoscale Silver A. Presentation Dr. ...

  3. Presentations at ASCCT 2023 66KB

    https://ntp.niehs.nih.gov/whatwestudy/niceatm/publications-and-presentations/presentations-at-scientific-meetings/ascct-2023/ascct-2023

    Twelfth Annual Meeting: American Society for Cellular and Computational Toxicology October 23-25 - Silver Spring, MD, USA NICEATM authors in bold; ICCVAM authors in bold italics ...

  4. Abstract for TR-88 64KB

    https://ntp.niehs.nih.gov/publications/reports/tr/000s/tr088

    Abstract 1H-Benzotriazole is an anticorrosive chemical used primarily on copper, but also on iron, steel, cadmium, chromium, zinc, and silver-nickel alloys. A bioassay of ...

  5. RoC Review of Cumene 71KB

    https://ntp.niehs.nih.gov/whatwestudy/assessments/cancer/completed/cumene

    17270 RoC Review of Cumene Woman pumping gasoline into a silver car Substance Overview CASRN: 98-82-8 Status: RoC: Reasonably anticipated to be a human carcinogen Primary Uses or ...

  6. Nose - Fungus 365KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/respiratory/nose/fungus/nose-fungus-pdf_508.pdf

    Figure 4 Nose - Fungus in a male F344/N rat from a chronic study. Silver staining techniques, such as this Gomori's methenamine silver stain, highlight the fungal organisms. ...

  7. Agency Response to ICCVAM Recommendations on LUMI-CELL Test Method 1.4MB

    https://ntp.niehs.nih.gov/iccvam/methods/endocrine/transmitfeb12/fda-response.pdf

    Food and Drug Administration Silver Spring, MD 20993 March 8, 2012 RADM William S. Stokes, Director, National Toxicology Program Interagency Center for the Evaluation of ...

  8. FDA Response to ICCVAM Recommendations on the LLNA 764KB

    https://ntp.niehs.nih.gov/iccvam/methods/immunotox/transmitsept09/fda-response.pdf

    DEPARTMENT OF HF.ALTH & HUMAN SERVICES Food and Drug Administration Silver Spring. MD 20993 March 18,2010 w(g©(gO'V~ ~ MAR 2 3 2010 ~ RADM William S. Stokes Director NICEATM ...

  9. ICCVAM Committee Roster (Feb 2024 - includes contact information... 144KB

    https://ntp.niehs.nih.gov/sites/default/files/2023-10/ICCVAM-Roster-Long.pdf

    ... Avenue Building 71-Room 3336 Silver Spring, MD 20993 Allen Wensky, PhD DHHS/FDA/CBER/OMPT/CBER/OTAT/DCEPT/PT Bll Building W071, Room 5203 Silver Springs, MD 20993 * Principal ...

  10. Peer Review Report: RoC Peer Review; Aug. 12, 2014 198KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2014/august/sep_report20140812_508.pdf

    ... Substances and Disease Registry Sharon Silver, National Institute for Occupational ... Dr. Sharon Silver attended representing the National Institute for Occupational Safety and ...

  11. Poster Abstract: Evaluation of Ocular Exposure to Leptospira... 27KB

    https://ntp.niehs.nih.gov/iccvam/meetings/leptovaccwksp-2012/posters/alt-abstract-508.pdf

    Tissues were obtained for culture, indirect fluorescent antibody testing (FAT), and silver ... were negative by culture, FAT, and silver stain at each of the timepoints evaluated. ...

  12. RoC Monograph: Trichloroethylene; January 2015 4.6MB

    https://ntp.niehs.nih.gov/ntp/roc/monographs/finaltce_508.pdf

    ... Consultant KP Cantor Environmental, LLC Silver Spring, Maryland, USA John M. Cullen, ... Silver et al. (2014) conducted a cohort mortality analysis of New York electronics ...

  13. Transmittal of ICCVAM Recommendations on the LLNA (June 2011... 45KB

    https://ntp.niehs.nih.gov/iccvam/methods/immunotox/transmitjuly11/hamburgltr30june11f.pdf

    The Honorable Margaret Hamburg, M.D. Commissioner U.S. Food and Drug Administration 10903 New Hampshire Avenue, Room 2217 Silver Spring, Maryland 20993 Dear Dr. Hamburg: I am ...

  14. Federal Agency Response to ICCVAM Recommendations on the LLNA 1.1MB

    https://ntp.niehs.nih.gov/iccvam/methods/immunotox/transmitjune10/fda-response.pdf

    JAN 1 3 201 1 iU ......---~~ ("'~DEPARTMRNT OF RE.Lm AND HUMAN SERVICE>; ~f-___... _ __ Food and Drug Adm,nistratlon Silver Spring MD 20993 January 6, 2011 RADM William S. Stokes ...

  15. Transmittal of ICCVAM Recommendations on the LLNA (June 2010... 44KB

    https://ntp.niehs.nih.gov/iccvam/methods/immunotox/transmitjune10/hamburgltr10june10f-lb.pdf

    The Honorable Margaret Hamburg, M.D. Commissioner U.S. Food and Drug Administration 10903 New Hampshire Avenue Room 2217 Silver Spring, MD 20993 Dear Dr. Hamburg: I am pleased to ...

  16. Research Concept: Cobalt; 2014 690KB

    https://ntp.niehs.nih.gov/ntp/roc/concept_docs/2014/cobalt_508.pdf

    metal (CAS No. 7440-48-4) is a naturally occurring shiny brittle silver-gray metallic element with ferromagnetic properties, which is used in a variety of industrial applications. ...

  17. Nerve - Axonopathy - Nonneoplastic Lesion Atlas 303KB

    https://ntp.niehs.nih.gov/atlas/nnl/nervous-system/brain/Axonopathy

    In specialized toxicologic-neuropathologic studies, use of special axonal stains such as Bielschowsky silver impregnation and de Olmos amino cupric silver to highlight the normal ...

  18. Transmittal to Federal Agencies of ICCVAM Recommendations on... 220KB

    https://ntp.niehs.nih.gov/iccvam/methods/endocrine/transmitfeb12/hamburgltr01feb12f.pdf

    February 1, 2012 The Honorable Margaret Hamburg, M.D. Commissioner U.S. Food and Drug Administration 10903 New Hampshire Avenue, Room 2217 Silver Spring, Maryland 20993 Dear Dr. ...

  19. Transmittal of ICCVAM Recommendations on In Vitro Ocular Test... 206KB

    https://ntp.niehs.nih.gov/iccvam/methods/ocutox/transmit2010/hamburg.pdf

    September 2, 2010 The Honorable Margaret Hamburg, M.D. Commissioner U.S. Food and Drug Administration 10903 New Hampshire Avenue, Room 2217 Silver Spring, Maryland 20993 Dear Dr. ...

  20. RoC Background Document: Cadmium; Oct. 30-31, 1997 13.0MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/cadmium_508.pdf

    ... 1.1 Chemical Identification Cadmium is a silver-white, blue-tinged, malleable metal. ... nickel, antimony, copper, lead, zinc, gold, silver, molybdenum, and platinum ore. ...

  21. RoC Profile: Thiourea; 15th RoC 2021 126KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/thiourea.pdf

    dioxide (30%), in leaching of gold and silver ores (25%), in diazo papers (blueprint ... It is also used as an ingredient of consumer silver polishes (HPD 2009), and has been used ...

  22. RoC Profile: Trichloroethylene; 15th RoC 2021 237KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/trichloroethylene.pdf

    ... Hansen et al. 2013, Bove et al. 2014, Silver et al. 2014) and case-con- trol studies ... Vlaanderen et al. 2013, Bove et al. 2014, Silver et al. 2014), four case-control studies ...

  23. Abstract for TR-578 78KB

    https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr578

    CASRN: 90045-36-6 Synonyms/Common Names: Ginkgo; ginkgo biloba; fossil tree; maidenhair tree; Japanese silver apricot; baiguo; bai guo ye; kew tree; yinhsing (yin-hsing); ginkgo ...

  24. Compilation and Characterization of a Human Skin Sensitization... 1.6MB

    https://ntp.niehs.nih.gov/iccvam/meetings/ascct-2021/poster/strickland-hppt.pdf

    RTP, NC, USA; 2 RIFM, Woodcliff Lake, NJ, USA; 3 US CPSC, Rockville, MD, USA; 4 NIH/NIEHS/DNTP/NICEATM, RTP, NC, USA; 5 US FDA, Silver Spring, MD, USA; 6 BfR, Berlin, Germany . ...

  25. Variability of Human Reference Data for Skin Sensitization 861KB

    https://ntp.niehs.nih.gov/iccvam/meetings/sot22/poster/strickland-variability-sot2022.pdf

    RTP, NC, USA; 2 CPSC, Rockville, MD, USA; 3 NIH/NIEHS/DNTP/NICEATM, RTP, NC, USA; 4 RIFM, Woodcliff Lake, NJ, USA; 5 FDA/CDER, Silver Spring, MD, USA; 6 BfR, Berlin, Germany . ...

  26. Properties and Human Exposure; Sanford Garner; RoC; Jan. 24,... 739KB

    https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2018/january/presentations/properties_508.pdf

    Elemental antimony is a silver-white metal used to make alloys . Antimony(III) trioxide exists as an odorless white powder or polymorphic crystals Antimony and antimony compounds ...

  27. TR-471: Cobalt Sulfate Heptahydrate (CASRN 10026-24-1) in F344... 13.1MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr471.pdf

    ... Male mice had a pattern of nonneoplastic liver lesions along with silver-staining helical ... exposure to cobalt sulfate Warthin Starry silver stain. heptahydrate, nor was the ...

  28. Human Reference Database for Skin Sensitization 124KB

    https://ntp.niehs.nih.gov/iccvam/meetings/ascct-2020/strickland-ascct2020-508.pdf

    4 NIH/NIEHS/DNTP/NICEATM, Research Triangle Park, NC, United States; 5 FDA/CDER, Silver Spring, MD, United States; 6 BfR, Berlin, Germany To support the evaluation of ...

  29. Compilation and Characterization of a Human Skin Sensitization... 23KB

    https://ntp.niehs.nih.gov/iccvam/meetings/ascct-2021/strickland_hppt_ascct2021_508.pdf

    .../DNTP/NICEATM, Research Triangle Park, NC, USA; 5 US Food and Drug Administration, Silver Spring, MD, USA; and 6 German Federal Institute for Risk Assessment, Berlin, Germany ...

  30. Classification of Human Reference Data for Skin Sensitization... 22KB

    https://ntp.niehs.nih.gov/iccvam/meetings/sot20/strickland-508.pdf

    MD, United States; 4 NIH/NIEHS/DNTP/NICEATM, RTP, NC, United States; 5 FDA/CDER, Silver Spring, MD, United States; 6 BfR, Berlin, Germany To support the evaluation of ...

  31. Variability of Human Reference Data for Skin Sensitization 44KB

    https://ntp.niehs.nih.gov/iccvam/meetings/sot22/strickland_508.pdf

    RTP, NC, United States; 4 RIFM, Woodcliff Lake, NJ, United States; 5 FDA/CDER, Silver Spring, MD, United States; 6 BfR, Berlin, Germany Because humans are the primary ...

  32. Brain - Axonopathy 567KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/nervous/brain/axonopat/brain-axonopathy_508.pdf

    ... In specialized toxicologic-neuropathologic studies, use of special axonal stains such as Bielschowsky silver impregnation and de Olmos amino cupric silver to highlight the normal ...

  33. Presentation: AOPs and Regulatory Decisions: Problem Formulation... 3.0MB

    https://ntp.niehs.nih.gov/iccvam/meetings/aop-wksp-2014/presentations/schoeny-508.pdf

    Thomas Burke; presentation 09/10 9 NRC Silver Book Recommendation µ NRC Silver Book recommendation (Chapter 8 "Improving Utility of Risk Assessment") µ To make risk assessments ...

  34. Evaluation of Skin Sensitization Classification Rules to Reflect... 181KB

    https://ntp.niehs.nih.gov/iccvam/meetings/sot23/herzler-sot2023-abstract_508.pdf

    RTP, NC, United States, 5 U.S. CPSC, Rockville, MD, United States; 6 FDA/CDER, Silver Spring, MD, United States To support development of Organisation for Economic ...

  35. Validation of the Electrophilic Allergen Screening Assay (EASA... 1.3MB

    https://ntp.niehs.nih.gov/iccvam/meetings/sot23/sot2023-gordon-poster.pdf

    Aberdeen Proving Ground, MD; 4 FDA/CDRH, Silver Spring, MD; 5 NIST, Gaithersburg, MD; 6 Burleson Research Technologies, Morrisville, NC; 7 NIH/NIEHS/DTT/PTB/NICEATM, RTP, NC. . ...

  36. TR-464: Technical Grade Sodium Xylene Sulfonate (CASRN 1300-72... 9.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr464.pdf

    ... Male mice had a pattern of nonneoplastic liver lesions along with silver stained positive ... Qualitatively, the hepatitis and silver-staining organisms within the liver were similar ...

  37. TR-469: AZT (CASRN 30516-87-1) and AZT/a-Interferon A/D B6C3F1Mice... 15.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr469.pdf

    ... of nonneoplastic liver lesions along with silver-staining helical organisms within the ... and sciatic nerve from all mice were also stained with Luxol fast blue and Holmes silver. ...

  38. A Proposal to Revise GHS Skin Sensitization Classification Rules... 101KB

    https://ntp.niehs.nih.gov/iccvam/meetings/ascct-2022/strickland-ascct2022-abstract_508.pdf

    .../DNTP/NICEATM, Research Triangle Park, NC, USA; 5 U.S. Food and Drug Administration, Silver Spring, MD, USA; and 6 German Federal Institute for Risk Assessment, Berlin, Germany ...

  39. Validation of the Electrophilic Allergen Screening Assay (EASA... 144KB

    https://ntp.niehs.nih.gov/iccvam/meetings/sot23/gordon-sot2023-abstract_508.pdf

    Public Health- Aberdeen, Aberdeen Proving Ground, MD, United States; 4 FDA/CDRH, Silver Spring, MD, United States; 5 NIST, Gaithersburg, MD, United States; 6 NIH/NIEHS/DTT/...

  40. TR-471: Cobalt Sulfate Heptahydrate (CASRN 10026-24-1) in F344... 9.0MB

    https://ntp.niehs.nih.gov/sites/default/files/2023-08/tr471_508.pdf

    ... Male mice had a pattern of nonneoplastic liver lesions along with silver-staining helical ... hepaticus when examined using Steiner's modification of the Warthin Starry silver stain. ...

  41. Evaluation of Skin Sensitization Classification Rules to Reflect... 60KB

    https://ntp.niehs.nih.gov/sites/default/files/2023-09/to_ascct2023_hppt_abstract_508.pdf

    Research Triangle Park, NC, USA, 6 United States Food and Drug Administration, Silver Spring, MD, USA *Presenting author To support development of the Organisation for ...

  42. Kidney - Glomerulonephritis - Nonneoplastic Lesion Atlas 292KB

    https://ntp.niehs.nih.gov/atlas/nnl/urinary-system/kidney/Glomerulonephritis

    Membranoproliferative GN is characterized by basement membrane thickening, either uniform or irregular, which can be demonstrated by periodic acid-Schiff or silver stains. ...

  43. Stomach, Glandular Stomach, Neuroendocrine Cell - Hyperplasia 513KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/alimentary/glandular_stomach/nehyp/glandular-stomach-neuroendocrine-cell-hyperplasia_508.pdf

    Munger stain). The cells separating the glands stain positively with a silver stain. Figure 5 Stomach, Glandular stomach, Neuroendocrine cell - Hyperplasia in a female F344/N rat ...

  44. TR-449: Triethanolamine (CASRN 102-71-6) in F344 Rats and B6C3F1Mice... 10.1MB

    https://ntp.niehs.nih.gov/go/tr449

    ... Male mice had a pattern of nonneoplastic liver lesions along with silver-staining helical ... Qualitatively, the hepatitis and the silver-staining organisms within the liver were ...

  45. Implementing the Strategic Roadmap 2.4MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2020/september/present/1-2-kleinstreuer-508.pdf

    ... Silver Spring. MO. USA; ~ermatologic and Dental Drug Products. U.S. .l!.S. P.O. &u J3SOJ , Rtuonli Trua:k An. NC 2"°9. USA Food and Drug Ad_ minis uation, Silver Spring, MD, USA; ...

  46. Workshop Report: Alternative Methods to Replace Animal Use for... 10.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/biologics-docs/bontwkshprept.pdf

    ... Center for Drug Evaluation and Research, Silver Spring, MD ix Workshop on Alternative ... for Biologics Evaluation and Research, Silver Spring, MD Andy Pickett, Ph.D. ...

  47. TR-473: Theophylline (CASRN 58-55-9) in F344/N Rats and B6C3F1Mice... 11.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr473.pdf

    ... Male mice had a pattern of nonneoplastic liver lesions along with silver-staining helical ... Starry silver stain. TABLE 24 Incidences of Neoplasms and Nonneoplastic Lesions of the ...

  48. McFarland et al: Non-animal replacement methods for human vaccine... 1019KB

    https://ntp.niehs.nih.gov/iccvam/meetings/leptovaccwksp-2012/refs/mcfarlandetal2011-508.pdf

    b United States Food and Drug Administration- Center for Drug Evaluation and Research, Silver Spring, Maryland, USA, c National Toxicology Program Interagency Center for the ...

  49. RoC References: Antimony and Other Antimony Compounds; Aug. 17... 830KB

    https://ntp.niehs.nih.gov/ntp/roc/references/antimonyreferences_508.pdf

    ... K. 2009. Genotoxicity studies of heavy metals: lead, bismuth, indium, silver and antimony. ... exploited fishes of an endorheic saline lake in the tin-silver province of Bolivia. ...

  50. Bone marrow - Fibrosis - Nonneoplastic Lesion Atlas 292KB

    https://ntp.niehs.nih.gov/atlas/nnl/hematopoietic-system/bone-marrow/Fibrosis

    Modest increases in reticulin fibers can be difficult to appreciate but can be confirmed with a silver impregnation technique, such as Gomori stain. Collagen fibers are identified ...

 
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