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RoC Background Document: Cadmium; Oct. 30-31, 1997 13.0MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/cadmium_508.pdf
CADMIUM FINAL MARCH 1999 Prepared for the October 30-31, 1997, Meeting of the Report on ... N01-ES-25346 NTP Report on Carcinogens 1997 Background Document for Cadmium TABLE OF ...
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TOX-39: Cadmium Oxide (CASRN 1306-19-0) 2.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox039.pdf
Technical Report on Toxicity Studies of Cadmium Oxide (CAS No. 1306-19-0) Administered by ... Technical Report on Toxicity Studies of Cadmium Oxide (CAS No. 1306-19-0) Administered by ...
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RoC Profile: Cadmium and Cadmium Compounds; 15th RoC 2021 162KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/cadmium.pdf
Cadmium and Cadmium Compounds CAS No. 7440-43-9 (Cadmium) No separate CAS No. assigned for cadmium compounds as a class Known to be human carcinogens First listed in the First ...
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Abstract for TOX-39 63KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox039
Abstract for TOX-39 Toxicity Studies of Cadmium Oxide Administered by Inhalation to F344/N ... Full Report PDF Abstract Three thousand tons of cadmium are imported or produced annually ...
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Minutes: BSC; Dec. 6, 2007 262KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2007/december/bsc_mins2007dec06_508.pdf
25 VII. Review of Lead and Cadmium for the Center for the Evaluation of...... 26 Risk to Human Reproduction (CERHR) Cadmium......
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Abstract for TR-88 64KB
https://ntp.niehs.nih.gov/publications/reports/tr/000s/tr088
Abstract 1H-Benzotriazole is an anticorrosive chemical used primarily on copper, but also on iron, steel, cadmium, chromium, zinc, and silver-nickel alloys. A bioassay of ...
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RoC References: Antimony and Other Antimony Compounds; Aug. 17... 830KB
https://ntp.niehs.nih.gov/ntp/roc/references/antimonyreferences_508.pdf
... 14. Ades AE, Kazantzis G. 1988. Lung cancer in a non-ferrous smelter: the role of cadmium. ... for antimony, arsenic, and metals (lead, cadmium, nickel, mercury, thallium, and uranium) ...
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Fruit Flies for Precision Toxicology & Medicine (SACATM Meeting... 5.9MB
https://ntp.niehs.nih.gov/sites/default/files/2023-11/09_Oliver_SACATM2023_508.pdf
Population Sex 5 Females are strikingly resistant to Cadmium 100% 80% 60% ☠ 40% 20% 0.0% Males 0 1 2 3 4 Females 6 Cadmium Chloride (mM) Cadmium Chloride (mM) Model Organism ...
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NTP Monograph on Health Effects of Low-Level Lead Appendix D... 543KB
https://ntp.niehs.nih.gov/ntp/ohat/lead/final/leadappendixd_final_508.pdf
Part of the OSCAR (osteoporosis- cadmium as a risk factor study Year not stated Male = 47% ... Urinary α 1 - microglobulin Multiple linear regression Age, smoking status, blood cadmium ...
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Testis - Fibrosis - Nonneoplastic Lesion Atlas 287KB
https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/testis/Fibrosis
Testicular fibrosis is induced in rats by chronic cocaine or cadmium administration. ... and multiple oral and subcutaneous cadmium administrations on the testes of Wistar rats. ...
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Testis - Fibrosis 697KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/male_reproductive/testis/fibrosis/testis-fibrosis_508.pdf
Testicular fibrosis is induced in rats by chronic cocaine or cadmium administration. ... and multiple oral and subcutaneous cadmium administrations on the testes of Wistar rats. ...
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TOX-35: Chemical Mixture of 25 Groundwater Contaminants 11.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox35.pdf
... 9 Benzene 5 .0 0 .375 1 .25 3 .75 12 .5 Cadmium 0 .85 1 .53 5 .1 15 .3 51 Carbon ... With the exception of three metals (cadmium, chromium, and nickel) for which the maximum ...
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Listed Substances; 15th RoC 2021 76KB
https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf
Chloromethyl Methyl Ether 1,3-Butadiene 1,4-Butanediol Dimethanesulfonate Cadmium and Cadmium Compounds Chlorambucil 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea ...
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National Institute of Environmental Health Sciences: Shawn Jeter 151KB
https://www.niehs.nih.gov/research/atniehs/dtt/assoc/opo/staff/shawn
Diselenide, Copper Indium Diselenide, and Cadmium Telluride in Sprague-Dawley rats. ... Diselenide, Copper Indium Diselenide, and Cadmium Telluride in Sprague-Dawley rats. ...
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Bone - Increased Osteoid - Nonneoplastic Lesion Atlas 289KB
https://ntp.niehs.nih.gov/atlas/nnl/musculoskeletal-system/bone/IncreasedOsteoid
Increased osteoid has been induced in rats by various compounds that inhibit mineralization of osteoid, including bisphosphonates, aluminum, cadmium, phosphorus deficiency, and ...
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NTP Monograph on Health Effects of Low-Level Lead Appendix C... 1.2MB
https://ntp.niehs.nih.gov/ntp/ohat/lead/final/leadappendixc_final_508.pdf
... (1991) 1648 adults (827 men, 821 women; Cadmium in Belgium (Cadmibel) Study; Year: ... not occupationally exposed to Pb or cadmium; Year not stated Male = 100% Exposed: ...
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Validation of In Vitro Cytotoxicity Test Methods: Test Chemicals 188KB
https://ntp.niehs.nih.gov/iccvam/methods/acutetox/invitrocyto/ivcytodocs/valstdchm.pdf
aid 10043-35-3 61.83 FLUKA 15660 100.1 Busulphan 55-98-1 246.31 FLUKA 19012 100.2 Cadmium II chloride 10108-64-2 183.31 FLUKA 20899 99.8 Caffeine 58-08-2 194.20 FLUKA 27600 ...
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Bone - Increased Osteoid 477KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/musculoskeletal/bone/incost/bone-increased-osteoid-pdf_508.pdf
Increased osteoid has been induced in rats by various compounds that inhibit mineralization of osteoid, including bisphosphonates, aluminum, cadmium, phosphorus deficiency, and ...
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Testis, Seminiferous Tubule - Necrosis - Nonneoplastic Lesion... 291KB
https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/testis/SeminiferousTubule-Necrosis
Chemically induced testicular necrosis has been described in rodents administered cadmium, ... Aoki A, Hoffer AP. 1978. Reexamination of the lesions in rat testis caused by cadmium. ...
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Comparative Genomics for Precision Toxicology (Population Variability... 20.9MB
https://ntp.niehs.nih.gov/iccvam/meetings/popvar-2022/ppt/06_oliver_508.pdf
Accidents Ischemic Heart Breast Cancer Rheumatic Heart 100% 80% 60% 40% 20% 0.0% Females Males ☠ ☠ 0 1 2 3 4 Cause of Death Cadmium Chloride (mM) Cadmium Chloride (mM) 6 ...
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Testis, Seminiferous Tubule - Necrosis 747KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/male_reproductive/testis/setubnecr/testis_seminiferous_tubule_-necrosis_508.pdf
Chemically induced testicular necrosis has been described in rodents administered cadmium, ... Aoki A, Hoffer AP. 1978. Reexamination of the lesions in rat testis caused by cadmium. ...
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NTP at the SOT; 2007 433KB
https://ntp.niehs.nih.gov/ntp/meetings/2007/ntpsot20070329_508.pdf
... Rats and B6C3F1 Mice (J. B. Bishop) 2073-366 Yuxia Cui Cadmium, Mercury & Metallothionein: Toxicogenomic Analysis of Cadmium Responsive Transcription in Caenorhabditis elegans ...
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Completed RoC Evaluations 119KB
https://ntp.niehs.nih.gov/whatwestudy/assessments/cancer/completed/roc
... RoC Review of 1-Bromopropane 1,3-Butadiene Known to be a human carcinogen Background Document Request Archived Materials Cadmium and Cadmium Compounds Known to be a human ...
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FDA Update: ICCVAM Public Forum 2017 450KB
https://ntp.niehs.nih.gov/iccvam/meetings/iccvam-forum-2017/03g-jacobs-fda-508.pdf
... In vitro human airway tissue model - Tight junction disruption by cadmium 16 NCTR: ... cells and ciliated cells Effect of Cadmium on Pulmonary Epithelium Cadmium is a ...
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RoC Profile: Hexachloroethane; 15th RoC 2021 145KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/hexachloroethane.pdf
and is considered nonflammable; how- ever, it is incompatible or reactive with alkalis and with metals such as zinc, cadmium, aluminum, hot iron, and mercury (NIOSH 2005). ...
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Draft RoC Monograph Cobalt Appendix: RoC Peer Review; July 22... 1.7MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_draftmonograph_appen.pdf
... et al. (2003) Germany Workers exposed to cadmium and cobalt 91 20 µg/g creatinine f NA ... Types of cancer not reported Cobalt levels correlated with other metals such as cadmium ...
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Appendix G; 15th RoC 2021 73KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf
... Arsenic Compounds 7440-41-7 (beryllium) see Beryllium and Beryllium Compounds 7440-43-9 (cadmium) see Cadmium and Cadmium Compounds 7440-48-4 (cobalt) see Cobalt-Related ...
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Validation, Qualification, and Regulatory Acceptance of New Approach... 2.9MB
https://ntp.niehs.nih.gov/sites/default/files/2024-03/VWG_Report_27Feb2024_FD_508.pdf
... 54 Supplemental Figure 4. Correlation of cadmium sulfate EC 50 values......56 Supplemental Figure 4. Correlation of cadmium sulfate (CdSO 4 ) EC 50 values determined ...
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TR592: Dietary Zinc (CASRN 5263-02-5) In Sprague Dawley Rats... 2.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr592_508.pdf
... The interaction of zinc with other metals, such as copper, cadmium, and cobalt, has also ... In vitro, cadmium also competes with zinc for binding to metallothionein 63 , and has been ...
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Revised Draft RoC Monograph Cobalt Appendix: RoC Peer Review... 1.7MB
https://ntp.niehs.nih.gov/ntp/roc/draftmono/revised_cobalt_append.pdf
... et al. 2003) Germany Workers exposed to cadmium and cobalt 91 20 µg/g creatinine f NA ... Types of cancer not reported Cobalt levels correlated with other metals such as cadmium ...
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RoC Profile: Coke-Oven Emissions; 15th RoC 2021 121KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/cokeovenemissions.pdf
... vapors, and gases that typ- ically include PAHs, formaldehyde, acrolein, aliphatic aldehydes, am- monia, carbon monoxide, nitrogen oxides, phenol, cadmium, arsenic, and mercury. ...
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RoC Profile: Soots; 15th RoC 2021 115KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/soots.pdf
... Soots are known to contain a number of known and potentially car- cinogenic chemicals, including arsenic, cadmium, chromium, nickel, and several polycyclic aromatic hydrocarbons ...
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RoC Monograph: Cobalt and Cobalt Compounds; April 2016 3.5MB
https://ntp.niehs.nih.gov/ntp/roc/monographs/cobalt_final_508.pdf
... Cobalt is used in nickel-cadmium, nickel-metal hydride, and lithium-ion battery ... Other risk factors of concern include exposure to arsenic, asbestos, cadmium, silica, ...
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NTP Monograph on Health Effects of Low-Level Lead 12.9MB
https://ntp.niehs.nih.gov/ntp/ohat/lead/final/monographhealtheffectslowlevellead_newissn_508.pdf
... This strategy would retrieve articles such as "low cadmium and lead levels" or "low blood ... known to cause kidney damage (e.g., cadmium, mer- cury, arsenic, zinc) (U.S. EPA ...
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Public Comment: Uranium (Attachment); Rosalie Bertell; RoC; Jan... 1.3MB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2012/publiccomm/bertellattachmentohw.pdf
... Other heavy metals, in addition to DU, especially mercury, lead, arsenic, and cadmium, were used extensively in the Gulf War. They were contained in pesticides and herbicides; in ...
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Lung - Emphysema - Nonneoplastic Lesion Atlas 292KB
https://ntp.niehs.nih.gov/atlas/nnl/respiratory-system/lung/Emphysema
... Tátrai E, Brózik M, Náray M, Adamis Z, Ungváry G. 2001. Combined pulmonary toxicity of cadmium chloride and sodium diethyldithiocarbamate. J Appl Toxicol 21:101-105. Abstract: ...
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Synthetic Turf/Recycled Tire Crumb Rubber 68KB
https://ntp.niehs.nih.gov/whatwestudy/topics/syntheticturf
... They range from polyaromatic hydrocarbons (PAHs) in carbon black to zinc oxide (ZnO), which is used as a hardening agent and could contain trace amounts of lead and cadmium oxides. ...
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Stomach, Glandular Stomach, Epithelium - Hyperplasia 285KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/respiratory/lung/emphysem/lung-emphysema-508.pdf
... 2 Lung - Emphysema References: Tátrai E, Brózik M, Náray M, Adamis Z, Ungváry G. 2001. Combined pulmonary toxicity of cadmium chloride and sodium diethyldithiocarbamate. ...
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RoC Background Document: Beryllium Compounds; Dec. 16-17, 1999 5.3MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/be_no_appendices_508.pdf
... IARC. 1993. Beryllium, Cadmium, Mercury and Exposures in the Glass Manufacturing Industry. ... Beryllium, cadmium, mercury and exposures in the glass manufacturing industry. IARC ...
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RoC Profile: Diglycidyl Resorcinol Ether; 15th RoC 2021 116KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/diglycidylresorcinolether.pdf
... National Library of Medicine. http://toxnet.nlm.nih.gov/ cgi-bin/sis/htmlgen?HSDB and search on CAS number. Last accessed: 5/09. IARC. 1976. Diglycidyl resorcinol ether. In Cadmium...
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Background Document: Styrene oxide; BSC RoC, Jan. 20-21, 2000 267KB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/bg_styrene_oxide_508.pdf
... 39 Appendix A: IARC. 1976. Cadmium, Nickel, Some Epoxides, Miscellaneous ... (1971) react with periodate, react with cadmium iodide- starch spectro- photometry not ...
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RoC Background Document for Lead and Lead Compounds - May 8,... 3.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/lead-public_508.pdf
... (Utah, U.S.) Rencher et al. 1977 Zinc, cadmium, and lead smelter workers (U.K.) Ades and ... study of lung cancer mortality among 4,393 U.K. zinc, lead, and cadmium smelter workers. ...
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RoC Profile: 4-Vinyl-1-cyclohexene Diepoxide; 15th RoC 2021 127KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/vinylcyclohexenediepoxide.pdf
... Last accessed: 8/20/09. IARC. 1976. 1-Epoxyethyl-3,4-epoxycyclohexane. In Cadmium, Nickel, Some Epoxides, Miscellaneous Industrial Chemicals and General Considerations on Volatile ...
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Abstract for RACB88036 62KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb88036
... In the presence of low doses of many known reproductive and developmental toxicants, including cadmium, mercury, lead, chloroform, and methylene chloride, relatively mild ...
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Draft RoC Monograph Cobalt: RoC Peer Review; July 22, 2015 2.8MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_draftmonograph.pdf
... Cobalt is used in nickel-cadmium (Ni-Cd), nickel-metal hydride (Ni-MH), and lithium- ion ... Other risk factors of concern include exposure to arsenic, asbestos, cadmium, silica, ...
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15th RoC: Appendix F 174KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf
... Cd see Cadmium and Cadmium Compounds CEP see Epichlorohydrin C.I. 42500 see Basic Red 9 Monohydrochloride C.I. 64500 see Disperse Blue 1 C.I. acid red 114 see 3,3'-Dimethylbenzidin...
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RoC Profile: Cobalt-Related Exposures; 15th RoC 2021 409KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/cobalt.pdf
... rechargeable batteries, including nickel-cadmium, nickel-metal hydride, and lithium-ion ... regulation of the rat lysyl oxidase gene in response to cobalt and cadmium. ...
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Revised Draft RoC Monograph Cobalt: RoC Peer Review; July 22... 3.0MB
https://ntp.niehs.nih.gov/ntp/roc/draftmono/revised_cobalt.pdf
... Cobalt is used in nickel-cadmium, nickel-metal hydride, and lithium-ion battery ... Other risk factors of concern include exposure to arsenic, asbestos, cadmium, silica, ...
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RoC Background Document: Tobacco Smoking; Dec. 2-3, 1998 3.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/environmentalts_noapps_508.pdf
... µg CIB (1991) Hoffmann and Hecht (1989) Cadmium 0.72 µg 0.1 µg CIB (1991) Hoffmann and ... np np 7440-38-2 74.9216 As 1 CEPA (1997) Cadmium Cd 0.72 µg/cig a 100 ng/cig b 7440-43-9 ...
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TOX-74: Cellulose Insulation 7.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox074_rev.pdf
... Mean concentrations of beryllium, cadmium, cobalt, chromium, potassium, molybdenum, ... 0.52 ± 0.01 0.53 ± 0.005 1.37 ± 0.001 Cadmium <0.0005 <0.0005 <0.0005 <0.0005 Calcium ...
