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RoC Monograph: Cobalt and Cobalt Compounds; April 2016 3.5MB
https://ntp.niehs.nih.gov/ntp/roc/monographs/cobalt_final_508.pdf
Cobalt and Cobalt CoMpounds that Release Cobalt ions in ViVo ROC MONOGRAPH 06 APRIL 2016 Report on Carcinogens Monograph on Cobalt and Cobalt Compounds That Release Cobalt Ions In ...
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TR-581: Cobalt Metal (CASRN 7440-48-4) in F344/N Rats and B6C3F1... 9.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr581_508.pdf
The Toxicology STudieS of cobalT MeTal (caSRN 7440-48-4) iN f344/N RaTS aNd b6c3f1/N Mice aNd Toxicology aNd caRciNogeNeSiS STudieS of cobalT MeTal iN f344/NTac RaTS aNd b6c3f1/N ...
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Draft RoC Monograph Cobalt: RoC Peer Review; July 22, 2015 2.8MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_draftmonograph.pdf
Cobalt and Certain Cobalt Compounds June 5, 2015 Office of the Report on Carcinogens Division of the National Toxicology Program National Institute of Environmental Health ...
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Background Document: RoC: Cobalt-Tungsten Carbide: Powders and... 1.9MB
https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/hardmetalsbd20100408_508.pdf
Report on Carcinogens Background Document for Cobalt-Tungsten Carbide: Powders and Hard ... Left Blank RoC Background Document for Cobalt-Tungsten Carbide: Powders and Hard Metals ...
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TR-471: Cobalt Sulfate Heptahydrate (CASRN 10026-24-1) in F344... 13.1MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr471.pdf
THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF COBALT SULFATE HEPTAHYDRATE (CAS NO. ... NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF COBALT SULFATE ...
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TR-471: Cobalt Sulfate Heptahydrate (CASRN 10026-24-1) in F344... 9.0MB
https://ntp.niehs.nih.gov/sites/default/files/2023-08/tr471_508.pdf
NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF COBALT SULFATE ... Toxicology and Carcinogenesis Studies of Cobalt Sulfate Heptahydrate in F344/N Rats and ...
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Revised Draft RoC Monograph Cobalt: RoC Peer Review; July 22... 3.0MB
https://ntp.niehs.nih.gov/ntp/roc/draftmono/revised_cobalt.pdf
Monograph on Cobalt and Cobalt Compounds That Release Cobalt Ions In Vivo November 6, 2015 Office of the Report on Carcinogens Division of the National Toxicology Program National ...
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RoC Profile: Cobalt-Related Exposures; 15th RoC 2021 409KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/cobalt.pdf
Soluble Cobalt Compounds Genotoxicity DNA repair inhibition ROS/oxidative stress HIF-1α stabilization Ion channels Endocytosis (lysosomal dissolution) Cobalt Form Cellular ...
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Draft RoC Monograph Cobalt Appendix: RoC Peer Review; July 22... 1.7MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_draftmonograph_appen.pdf
Cobalt and Certain Cobalt Compounds Appendices June 5, 2015 Office of the Report on Carcinogens Division of the National Toxicology Program National Institute of Environmental ...
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TOX-5: Cobalt Sulfate Heptahydrate CASRN 10026-24-1 2.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox005.pdf
NTP REPORT ON THE TOXICITY STUDIES OF COBALT SULFATE HEPTAHYDRATE IN F344/N RATS AND B6C3F ... Cobalt Sulfate Heptahydrate, NTP TOX 5 TOXICITY STUDIES OF COBALT SULFATE HEPTAHYDRATE ...
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TOX-05: Cobalt Sulfate Heptahydrate in F344/N Rats and B6C3F1... 2.7MB
https://ntp.niehs.nih.gov/sites/default/files/2023-08/tox05_508.pdf
NTP REPORT ON THE TOXICITY STUDIES OF COBALT SULFATE HEPTAHYDRATE IN F344/N RATS AND B6C3F ... the NTP Report on the Toxicity Studies of Cobalt Sulfate Heptahydrate in F344/N Rats and ...
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Revised Draft RoC Monograph Cobalt Appendix: RoC Peer Review... 1.7MB
https://ntp.niehs.nih.gov/ntp/roc/draftmono/revised_cobalt_append.pdf
Monograph on Cobalt and Certain Cobalt Compounds That Release Cobalt Ions In Vivo Appendices November 6, 2015 Office of the Report on Carcinogens Division of the National ...
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RoC Protocol for Cobalt and Certain Cobalt Compounds 638KB
https://ntp.niehs.nih.gov/ntp/roc/protocols/cobalt_508.pdf
Protocol: Methods for Preparing the Draft Report on Carcinogens Monograph on "Cobalt and Certain Cobalt Compounds" Background information Cobalt is a naturally occurring element ...
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Cobalt-Tungsten Carbide Powders and Hard Metals Expert Panel... 6.5MB
https://ntp.niehs.nih.gov/ntp/roc/twelfth/2008/expertpanelmtgs/cobalt_panelreportparta_508.pdf
A - Peer Review of the Draft Background Document on Cobalt-Tungsten Carbide Powders and Hard Metals The Report on Carcinogens (RoC) expert panel for cobalt-tungsten carbide powders ...
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Cobalt-Tungsten Carbide Powders and Hard Metals Expert Panel... 700KB
https://ntp.niehs.nih.gov/ntp/roc/twelfth/2008/expertpanelmtgs/cobalt_panelreportpartb_508.pdf
Status for Cobalt-Tungsten Carbide Powders and Hard Metals and Scientific Justification for the Recommendation The Report on Carcinogens (RoC) expert panel for cobalt-tungsten ...
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Cobalt Literature Search StrategyRoC Peer Review; July 22, 2015 374KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_litsearchstrategy_508.pdf
Literature Search Strategy for Preparing the Report on Carcinogens Monograph on Cobalt and Certain Cobalt Compounds Introduction and objective The objective of the literature ...
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Presentation: Cobalt and Certain Cobalt Compounds: Mechanistic... 751KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/presentations/otherrelevantdata_508.pdf
Toxicokinetics Mechanistic and Other Relevant Data - Cobalt toxicity: particles versus ions - Proposed modes of action - Cobalt and certain cobalt compounds as a class Diet and ...
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Research Concept: Cobalt; 2014 690KB
https://ntp.niehs.nih.gov/ntp/roc/concept_docs/2014/cobalt_508.pdf
RoC Concept: Cobalt (October 2014) 1 Report on Carcinogens (RoC) Concept: Cobalt Project Leader: Diane L. Spencer, MS, Office of the RoC, DNTP, NIEHS 1 Background and rationale ...
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Peer Review Report: Draft Report on Carcinogens (RoC) Monograph... 236KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2015/july/sepreport20150722_508.pdf
National Toxicology Program Peer Review of Draft Report on Carcinogens (RoC) Monograph on Cobalt and Certain Cobalt Compounds July 22, 2015 National Institute of Environmental ...
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Presentation: Cobalt and Certain Cobalt Compounds: Properties... 908KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/presentations/humanexposure_508.pdf
Health Sciences July 22, 2015 Properties and Human Exposure Outline Properties and Human Exposure Properties: Description of cobalt and cobalt compounds Human exposure to cobalt . ...
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Presentation: Cobalt and Certain Cobalt Compounds Human Cancer... 479KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/presentations/humancancerstudies_508.pdf
Draft Monograph on Cobalt and Certain Cobalt Compounds Human Cancer Studies Pamela J. Schwingl, PhD Integrated Laboratory Systems, Inc. Contractor supporting the ORoC National ...
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Presentation: Cobalt and Certain Cobalt Compounds: Cancer Evaluation... 255KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/presentations/substance-profile_508.pdf
RoC Monograph on Cobalt and Certain Cobalt Compounds Diane L. Spencer, MS Office of the Report on Carcinogens National Institute of Environmental Health Sciences July 22, 2015 ...
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Presentation: Cobalt and Certain Cobalt Compounds Studies in... 539KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/presentations/experimentalanimals_508.pdf
Draft RoC Monograph on Cobalt and Certain Cobalt Compounds Studies in Experimental Animals Diane Spencer, MS Office of the Report on Carcinogens National Institute of ...
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Public Comment: Ruth Danzeisen of Cobalt Development Institute... 1.1MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/publiccomm/cdi20150708.pdf
the Cobalt Development Institute 8 July 2015 18 Jeffries Passage, Guildford, Surrey, GU1 ... Report on Carcinogens (RoC) Monograph on Cobalt" (published June 5, 2015), Comments ...
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RoC Review of Cobalt and Cobalt Compounds that Release Cobalt... 80KB
https://ntp.niehs.nih.gov/whatwestudy/assessments/cancer/completed/cobalt
97282 RoC Review of Cobalt and Cobalt Compounds that Release Cobalt Ions In Vivo Cobalt compound sitting in glass bowl on table Substance Overview Status: RoC: Reasonably ...
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Public Comment: Cobalt and Certain Cobalt Compounds; Andrew Monnot... 491KB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/publiccomm/monnot20131018_508.pdf
RE: Nominations to the Report on Carcinogens; Request for Information on Cobalt Dr. ... requesting the following information for cobalt (Co): (1) data on current production, use ...
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Abstract for TR-581 92KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr581
Abstract for TR-581 Toxicology Studies of Cobalt Metal in F344/N Rats and B6C3F1/N Mice and Toxicology and Carcinogenesis Studies of Cobalt Metal in F344/NTac Rats and B6C3F1/N Mice ...
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Abstract for TR-471 75KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr471
Abstract for TR-471 Toxicology and Carcinogenesis Studies of Cobalt Sulfate Heptahydrate ... 281.13 Synonyms/Common Names: Bieberite; cobalt(II) sulfate (1:1) heptahydrate; cobalt ...
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Public Comment: Ruth Danzeisen of Cobalt Development Institute... 153KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/publiccomm/cdi20150722_508.pdf
Comments on the RoC Monograph on Cobalt and Certain Cobalt Compounds July 22nd, 2015 RoC Monograph peer-review meeting Ruth Danzeisen, PhD, DABT on behalf of the Cobalt Development ...
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Presentation: Process for Preparing the Draft RoC Monograph for... 874KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/presentations/draftrocmonograph_508.pdf
Draft RoC Monograph on Cobalt and Certain Cobalt Compounds Process for Preparing the Draft RoC Monograph Ruth Lunn, DrPH Office of the Report on Carcinogens National Institute of ...
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Peer Review Report: RoC Peer Review; July 22, 2015 411KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/ntpresponsereportcobnov06_508.pdf
Carcinogens Monograph on Cobalt Public Meeting July 22, 2015 National Institute of Environmental Health Sciences November 6, 2015 NTP Response to Cobalt Peer-Review Report i ...
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Roster: RoC Cobalt-Tungsten Carbide Powders and Hard Metals Expert... 120KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/2008/expertpanelmtgs/cobalt_roster20081210.pdf
Report on Carcinogens (RoC) Cobalt-Tungsten Carbide Powders and Hard Metals Expert Panel Roster December 9 th -10 th , 2008 Max Costa, Ph.D., Chair Steven Markowitz, M.D. New York ...
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Abstract for TOX-05 62KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox005
Abstract for TOX-05 Toxicity Studies of Cobalt Sulfate Heptahydrate in F344/N Rats and ... Health Service. Toxicology studies of cobalt sulfate heptahydrate (99% pure) were ...
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Agenda: RoC Cobalt-Tungsten Carbide Powders and Hard Metals Expert... 111KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/2008/expertpanelmtgs/cobalt_agenda20081210.pdf
Report on Carcinogens (RoC) Cobal t-Tungsten Carbide Powders and Hard Metal s Expert Panel Meeting December 9-10, 2008 London Room Sheraton Chapel Hill Hotel Chapel Hill, North ...
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Agenda: Peer Review of Draft RoC Monograph: Cobalt and Certain... 67KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2015/july/sep_agenda_20150722_508.pdf
Peer Review of Draft Report on Carcinogens (RoC) Monograph on Cobalt and Certain Cobalt Compounds Agenda July 22, 2015, 9:00 AM EDT -- until adjournment National Institute of ...
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Report on Carcinogens (RoC) Expert Panel Meeting: Cobalt-Tungsten... 60KB
https://ntp.niehs.nih.gov/events/past/2000s/2008/panel_2008-12-09
Report on Carcinogens (RoC) Expert Panel Meeting: Cobalt-Tungsten Carbide Powders and Hard ... Report on Carcinogens (RoC) Expert Panel Meeting: Cobalt-Tungsten Carbide Powders and Hard ...
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Target Organs and Levels of Evidence for TR-581 63KB
https://ntp.niehs.nih.gov/data/tr/500s/tr581levels
1 Target Organs and Levels of Evidence for TR-581 Toxicology Studies of Cobalt Metal (CASRN 7440-48-4) in F344/N Rats and B6C3F1/N Mice and Toxicology and Carcinogenesis Studies of ...
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CDI Comments on ORoC 50KB
https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2015/june/publiccomm/danzeisen20151124_508.pdf
Ruth Danzeisen Nov 24, 2015 (on behalf of the Cobalt Development Institute) Oral comments on the revised RoC Monograph on Cobalt for the NTP Board of Scientific Counselors Meeting ...
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NeuwirthComment 128KB
https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2015/june/presentations/neuwirth20151112_508.pdf
White, I am writing to provide comment on the Revised Draft: Report on Carcinogens Monograph on Cobalt and Cobalt Compounds That Release Cobalt Ions In Vivo (Draft Monograph), ...
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Actions: RoC Peer Review; July 22, 2015 52KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2015/july/sep_actions_20150722_508.pdf
Actions from Peer Review of the Draft Report on Carcinogens Monograph on Cobalt and Certain Cobalt Compounds July 22, 2015 The NTP Monograph Peer-Review Panel ("the Panel") was ...
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Public Comment: David J. Wawer; Color Pigments Manufacturers... 217KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/publiccomm/wawer20160106.pdf
K2-03 Research Triangle Park, N.C. 27709 Re: Assessment of Cobalt and Certain Cobalt Compounds for Addition to the Report on Carcinogens of the National Toxicology Program Dear Dr. ...
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Minutes: BSC RoC; Nov. 11, 2008 624KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/draftbackgrounddocs/roc_minutes20021120.pdf
......... 13 Cobalt Sulfate......Cobalt Sulfate Dr. Lunn presented the nomination and said that cobalt sulfate is an ...
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Minutes: TR Panel; Oct. 29, 2013 234KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2013/october/minutes20131029_508.pdf
VI. Draft NTP Technical Report TR-581 on Cobalt Metal ......Brock, Duke University Ruth Danzeisen, Cobalt Development Institute (by telephone) ...
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Minutes: BSC; April 17-18, 2014 253KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2014/april/minutes20140418_508.pdf
8 X. Draft RoC Concept: Cobalt ......2014 NTP Board of Scientific Counselors X. Draft RoC Concept: Cobalt A. Presentation Ms. ...
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Target Organs and Levels of Evidence for TR-471 60KB
https://ntp.niehs.nih.gov/data/tr/400s/tr471levels
Toxicology and Carcinogenesis Studies of Cobalt Sulfate Heptahydrate (CASRN 10026-24-1) ... Route/Exposure Levels Study Laboratory Cobalt sulfate heptahydrate 10026-24-1 12/11/...
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Minutes: BSC; June 21-22, 2010 364KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2010/june/minutes20100622.pdf
for the 12 th Report on Carcinogens: Cobalt- Tungsten Carbide: Powders and Hard ... of Risks to Human Reproduction CoWC cobalt-tungsten carbide: powders and hard metals ...
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Minutes: BSC; Dec. 1-2, 2015 1.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2015/december/bsc_dec2015_minutes_508.pdf
on Carcinogens (ORoC) Report on Peer Review of the Draft RoC Monograph on Cobalt and Certain Cobalt Compounds ......
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NTP Response to BSC Peer Review Comments on the Draft Substances... 324KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/2011/response062110bsc2011.pdf
Meetings: Roster of Attending Members 3 Cobalt-Tungsten Carbide: Powders and Hard Metals ... candidate substances were reviewed: cobalt-tungsten carbide: powders and hard ...
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Charge: RoC Peer Review; July 22, 2015 23KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/sep_charge20150722_508.pdf
NATIONAL TOXICOLOGY PROGRAM Peer Review of Draft Report on Carcinogens (RoC) Monograph on Cobalt and Certain Cobalt Compounds July 22, 2015 Meeting The peer-review panel's charge ...
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RoC Background Document: Metallic Nickel and Certain Nickel Alloys... 1.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/ni_no_appendices_508.pdf
... contain variable amounts of nickel as well as other metals like chromium, iron and cobalt. ... 0.2 % Ni by weight (used for prostheses) Cobalt chromium molybdenum alloy na na Co-Cr-Mo ...
