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TR-461: Nitromethane (CASRN 75-52-5) in F344 Rats and B6C3F1Mice... 21.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr461.pdf
... . . . : . . . . . . ! - .. : . . . . 2 Nitromethane, NTP TR 461 CONTRIBUTORS National ... Nitromethane, N T P TR 461 . . ' . . . N T R O r n T M CAS NO.75-52-5 Molecular Weight: ...
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RoC Background Document for Nitromethane; March 25, 2002 1.2MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/nmpub_no_appendices_508.pdf
FINAL Report on Carcinogens Background Document for Nitromethane March 25, 2002 Prepared ... 3/25/02 RoC Background Document for Nitromethane FOREWORD The Report on Carcinogens ...
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TR-528: 2,2-bis(Bromomethyl)-1,3-Propanediol, Nitromethane, and... 5.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr528.pdf
THE CARCINOGENESIS STUDIES OF 2,2-BIS(BROMOMETHYL)-1,3-PROPANEDIOL, NITROMETHANE, AND 1,2,3-TRICHLOROPROPANE (CAS NOS. 3296-90-0, 75-52-5, and 96-18-4) IN GUPPIES (Poecilia ...
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RoC Profile: Nitromethane; 15th RoC 2021 136KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/nitromethane.pdf
Nitromethane CAS No. 75-52-5 Reasonably anticipated to be a human carcinogen First listed in the Eleventh Report on Carcinogens (2004) O 2 N - CH 3 Carcinogenicity Nitromethane is ...
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Nitromethane: Target Organs and Levels of Evidence for TR-461 59KB
https://ntp.niehs.nih.gov/data/tr/400s/tr461levels
0 Nitromethane: Target Organs and Levels of Evidence for TR-461 Toxicology and Carcinogenesis Studies of Nitromethane (CASRN 75-52-5) in F344 Rats and B6C3F1 Mice (Inhalation ...
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Abstract for TR-461 77KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr461
Abstract for TR-461 Toxicology and Carcinogenesis Studies of Nitromethane in F344/N Rats and B6C3F1 Mice (Inhalation Studies) CASRN: 75-52-5 Chemical Formula: CH3NO2 Molecular ...
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Target Organs and Levels of Evidence TR-528 66KB
https://ntp.niehs.nih.gov/data/tr/500s/tr528levels
Carcinogenesis Studies of 2,2-bis(Bromomethyl)-1,3-Propanediol, Nitromethane, and 1,2,3-Trichloropropane (CASRNs 3296-90-0, 75-52-5, and 96-18-4) in Guppies (Poecilia reticulata) ...
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Minutes: BSC TRRS; Feb. 17, 2004 661KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2004/feb/trrs17feb2004mins_508.pdf
2,2-bis(Bromomethyl)-1,3-propanediol, Nitromethane, and 1,2,3-Trichloropropane ... 2,2-bis(bromomethyl)-1,3-propanediol, nitromethane, and 1,2,3- trichloropropane in two ...
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Minutes: BSC RoC; Nov. 11, 2008 624KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/draftbackgrounddocs/roc_minutes20021120.pdf
......... 8 Nitromethane......Roberts seconded the motion, which was accepted unanimously with 9 yes votes. Nitromethane ...
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Abstract for TR-528 85KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr528
Carcinogenesis Studies of 2,2-bis(Bromomethyl)-1,3-Propanediol, Nitromethane, and ... Substances: 2,2-Bis-bromomethyl)- 1,3-propanediol (CASRN 3296-90-0) Nitromethane (CASRN ...
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Minutes: BSC TRRS; Dec. 5, 1995 178KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1995/dec/trrs5dec1995mins_508.pdf
Trioxide 1313-27-5 Inhalation ......5 Nitromethane 75-52-5 Inhalation ......7 Phenolphthalein 77-09-8 Feed ...
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TR-461 Pathology Tables and Curves 58KB
https://ntp.niehs.nih.gov/data/tables/tr/400s/tr461
1370 TR-461 Pathology Tables and Curves TR-461 NITROMETHANE Pathology Tables - Rats P03 - Incidence Rates of Non-Neoplastic Lesions By Anatomic Site P04 - Individual Animal Tumor ...
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RoC Profile: Tetranitromethane; 15th RoC 2021 125KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/tetranitromethane.pdf
the rela- tionship between human cancer and exposure specifically to tetra- nitromethane. ... the estimated worst-case tetra nitromethane level in the vicinity of the factories ...
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Agenda: BSC RoC; Nov. 19-20, 2002 50KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/meetings/2002/nov2002rocagenda.pdf
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine PhIP) (105650-23-6) Nitromethane (75-52-5) Listing in the 11th Report Diethanolamine (DEA) (111-42-2) Listing in the 11th ...
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Studies on Historical Control Reports for NIH-07 Feed 312KB
https://ntp.niehs.nih.gov/ntp/historical_controls/nih-07_1999/histcont_1999_by_list_of_studies_508.pdf
Rats Fischer344 Inhalation Air Nitromethane Rats Fischer344 Inhalation Air Ozone ... trioxide Mice B6C3F1 Inhalation Air Nitromethane Mice B6C3F1 Inhalation Air Ozone Mice ...
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Appendix G; 15th RoC 2021 73KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf
... Dichloromethane 75-21-8 see Ethylene Oxide 75-27-4 see Bromodichloromethane 75-52-5 see Nitromethane 75-55-8 see 2-Methylaziridine 75-56-9 see Propylene Oxide 75-96-7 ...
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Agenda: BSC TRRS; Feb. 17-18, 2004 82KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2004/feb/trrs17feb2004agenda_508.pdf
varnish remover. 2,2-Bis(bromomethyl)-1,3-propanediol /3296-90-0 Flame retardant Nitromethane /75-52-8 Fuel additive, synthesis intermediate and solvent Exposure by aquarium ...
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Harderian gland - Atrophy - Nonneoplastic Lesion Atlas 291KB
https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/harderian-gland/Atrophy
National Toxicology Program. 1997. NTP TR-461. Toxicology and Carcinogenesis Studies of Nitromethane (CAS No. 75-52-5) in F344/N Rats and B6C3F1 Mice (Inhalation Studies). NTP, ...
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Harderian gland - Hyperplasia - Nonneoplastic Lesion Atlas 293KB
https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/harderian-gland/Hyperplasia
... National Toxicology Program. 1997. NTP TR-461. Toxicology and Carcinogenesis Studies of Nitromethane (CAS No. 75-52-5) in F344/N Rats and B6C3F1 Mice (Inhalation Studies). NTP, ...
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Nose - Hyperplasia, Goblet Cell - Nonneoplastic Lesion Atlas 294KB
https://ntp.niehs.nih.gov/atlas/nnl/respiratory-system/nose/HyperplasiaGobletCell
... National Toxicology Program. 1997. NTP TR-461. Toxicology and Carcinogenesis Studies of Nitromethane (CAS No. 75-52-5) in F344/N Rats and B6C3F1 Mice (Inhalation Studies). NTP, ...
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Harderian Gland - Atrophy 269KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/special_senses/harderian/atrophy/harderian-gland-atrophy_508.pdf
.../7095 National Toxicology Program. 1997. NTP TR-461. Toxicology and Carcinogenesis Studies of Nitromethane (CAS No. 75-52-5) in F344/N Rats and B6C3F 1 Mice (Inhalation Studies). ...
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Harderian Gland - Hyperplasia 401KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/special_senses/harderian/hyperpl/harderian-gland-hyperplasia_508.pdf
... National Toxicology Program. 1997. NTP TR-461. Toxicology and Carcinogenesis Studies of Nitromethane (CAS No. 75-52-5) in F344/N Rats and B6C3F 1 Mice (Inhalation Studies). ...
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Nose - Hyperplasia, Goblet Cell 339KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/respiratory/nose/hypgc/nose-hyperplasia-goblet-cell-pdf_508.pdf
... National Toxicology Program. 1997. NTP TR-461. Toxicology and Carcinogenesis Studies of Nitromethane (CAS No. 75-52-5) in F344/N Rats and B6C3F1 Mice (Inhalation Studies). ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
.../Sex NT Chemical Not Tested in Species/Sex TR-528 02/18/04 Fish Project (Nitromethane) 75-52-5 FISH (Medaka) M = N F = N TR-528 02/18/04 Fish Project (2,2-bis-(Bromomethyl)-1,...
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TR-386: Tetranitromethane (CASRN 509-14-8) in F344/N Rats and... 12.9MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr386.pdf
... No current estimates of the amount of tetra- nitromethane intentionally produced were ... The estimated "worst case" pollutant level of tetra- nitromethane in the vicinity of the ...
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Technical Reports 903KB
https://ntp.niehs.nih.gov/publications/reports/tr
... Studies of 2,2-bis(Bromomethyl)-1,3-Propanediol, Nitromethane, and 1,2,3-Trichloropropane (CASRNs 3296-90-0, 75-52-5, and 96-18-4) in Guppies (Poecilia reticulata) and Medaka ...
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Listed Substances; 15th RoC 2021 76KB
https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf
... (see Nitroarenes [Selected]) Nitrofen Nitrogen Mustard Hydrochloride Nitromethane 2-Nitropropane 1-Nitropyrene (see Nitroarenes [Selected]) 4-Nitropyrene (see ...
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RoC Profile: 1,2,3-Trichloropropane; 15th RoC 2021 142KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/trichloropropane.pdf
... NTP. 2005. Carcinogenesis Studies of 2,2-Bis(bromomethyl)-1,3-propanediol, Nitromethane, and 1,2,3-Trichloropropane (CAS Nos. 3296-90-0, 75-52-5, and 96-18-4) in Guppies (Poecilia ...
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Completed RoC Evaluations 119KB
https://ntp.niehs.nih.gov/whatwestudy/assessments/cancer/completed/roc
... Request Archived Materials 6-Nitrochrysene Reasonably anticipated to be a human carcinogen Background Document Request Archived Materials Nitromethane Reasonably anticipated to be ...
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Study Reports 1.1MB
https://ntp.niehs.nih.gov/publications/reports
... Studies of 2,2-bis(Bromomethyl)-1,3-Propanediol, Nitromethane, and 1,2,3-Trichloropropane (CASRNs 3296-90-0, 75-52-5, and 96-18-4) in Guppies (Poecilia reticulata) and Medaka ...
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Toxicology/Carcinogenicity 1.1MB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox
... Studies of 2,2-bis(Bromomethyl)-1,3-Propanediol, Nitromethane, and 1,2,3-Trichloropropane (CASRNs 3296-90-0, 75-52-5, and 96-18-4) in Guppies (Poecilia reticulata) and Medaka ...
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Minutes: BSC; June 29, 2004 883KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2004/june/20040629_508.pdf
... Nitromethane - the recommendation is to list as reasonably anticipated to be a human ... Nitromethane, when inhaled, was carcinogenic in male and female mice and female rats, but ...
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CERHR Monograph: 1-Bromopropane 1.1MB
https://ntp.niehs.nih.gov/ntp/ohat/bromopropanes/1-bromopropane/1bp_monograph.pdf
... butylene oxide, 1,3-Dioxolane, nitromethane, dimethoxymethane, t-butanol, ... (95.5%) and also butylene oxide (<0.5%), 1,3-dioxolane (<2.5%), and nitromethane (<0.25%). ...
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TR-492: Gallium Arsenide (CASRN 1303-00-0) in F344/N Rats and... 23.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr492.pdf
... There is only one recent inhalation study (nitromethane; NTP, 1997) which has had a ... In the nitromethane study, 10/50 chamber control male mice had harderian gland adenoma or ...
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Nomination Background: 2,3-Butanedione (CASRN: 431-03-8) 1.8MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/artificial_butter_flavoring_508be.pdf
... NL NL NL Formic acid 64-18-6 284 NL NL NL Minor Minor NL Nitromethane Carbon disulfide 1,1,2-Trichloro-1,2,2-trifluoroethane (CFC 113) 75-52-5 75-15-0 76-13-1 6375 6348 6428 NL ...
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1-Bromopropane: Preliminary Literature Search Strategy and List... 639KB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/litsearchstrategy/1-bp-litsearch&references5oct2012_508.pdf
... Studies of 2,2-Bis(Bromomethyl)-1,3- Propanediol, Nitromethane, And 1,2,3-Trichloropropane (Cas Nos. 3296-90- 0, 75-52-5, and 96-18-4) in Guppies (Poecilia reticulata) and ...
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RR-11: The Chemical and Physical Characterization of Recycled... 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr11_508.pdf
... 99-09-2 138.12 4-Nitroaniline 100-01-6 138.12 Nitrobenzene 98-95-3 123.11 Nitromethane 75-52-5 61.04 2-Nitrophenol 88-75-5 139.11 4-Nitrophenol 100-02-7 139.11 ...
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TR-486: Isoprene (CASRN 78-79-5) in F344/N Rats (Inhalation Studies... 11.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr486.pdf
... trioxide 0/50 0/50 0/50 0/50 Nitromethane 1/50 0/50 0/50 1/50 .../50 Molybdenum trioxide 1/50 0/50 1/50 Nitromethane 0/50 0/50 0/50 o-Chlorobenzalmalononit...
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Minutes: BSC; April 17, 1996 335KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1996/april/19960417_bsc_508.pdf
... He noted that three of the chemicals, nitromethane, phenolphthalein, and tetrafluoroethylene, demonstrated clear evidence of carcinogenic activity. Dr. Hailey previewed the 10 ...
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National Toxicology Program, Board of Scientific Counselors 106KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2001/may/2001052501bscsummmins_508.pdf
... and GAMMA-Radiation, Neutrons, Occupational Exposure to Lead or Lead Compounds, Naphthalene, Nitrobenzene, Nitromethane, Phenylimidazopyridine (PhIP), and 4,4'-Thiodianiline. Dr. ...
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TR-482: Furfural Alcohol (CASRN 98-00-0) in F344/N Rats and B6C3F1... 27.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr482.pdf
.../50 Molybdenum Trioxide 0/50 0/50 0/50 Nitromethane 0/50 0/50 0/50 o-Chlorobenzalmalononit.../50 Molybdenum Trioxide 1/50 0/50 1/50 Nitromethane 0/50 0/50 0/50 o-Chlorobenzalmalononit...
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Public Health Impact 1.5MB
https://ntp.niehs.nih.gov/media/impact
... NTP (National Toxicology Program). 2005. Nitromethane. Report on ... Service. ) https://ntp.niehs.nih.gov/ntp/roc/content/profiles/nitromethane.pdf NTP (National Toxicology ...
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Appendices A-G; 15th RoC 2021 448KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf
... Dichloromethane 75-21-8 see Ethylene Oxide 75-27-4 see Bromodichloromethane 75-52-5 see Nitromethane 75-55-8 see 2-Methylaziridine 75-56-9 see Propylene Oxide 75-96-7 ...
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TR-499: Indium Phosphide (CASRN 22398-80-7) in F344/N Rats and... 19.3MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr499.pdf
... trioxide 0/50 0/50 0/50 0/50 Nitromethane 1/50 0/50 1/50 0/50 Ozone 1/50 1/50 2/... Molybdenum trioxide 15/50 2/50 15/50 Nitromethane 16/50 1/50 17/50 Ozone 17/50 1/50 17/...
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Minutes: BSC; Sept. 17, 2002 762KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2002/september/20020917bscsummmins_508.pdf
...2,4-dibromoanthraquinone, cobalt sulfate, diethanoamine, naphthalene, nitrobenzene, nitromethane, 4,4'-thiodianiline, and three selected heterocyclic amines - MeIQ ...
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TR-500: Naphthalene (CASRN 91-20-3) in F344/N Rats (Inhalation... 8.6MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr500.pdf
... Toxicology and Carcinogenesis Studies of Nitromethane (CAS No. 75-52-5) in F344/N Rats and B6C3F 1 Mice (Inhalation Studies). Technical Report Series No. 461. NIH Publication No. ...
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TR-490: Glutaraldehyde (CASRN 111-30-8) in F344/N Rats and B6C3F1Mice... 10.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr490.pdf
... Isoprene Molybdenum trioxide Nitromethane Ozone Tetrafluoroethylene ... Isoprene 0/48 Molybdenum trioxide 1/49 Nitromethane 0/50 Ozone 0/50 Tetrafluoroethylene 0/...
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TR-484: 2-Butoxyethanol (CASRN 111-76-2) in F344/N Rats and B6C3F1Mice... 11.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr484.pdf
... trioxide 5/49 1/49 0/49 6/49 Nitromethane 1/49 1/49 0/49 2/49 Ozone 6/50 0/50 0/... 1/50 Molybdenum trioxide 0/50 Nitromethane 0/50 Ozone 0/50 Tetrahydrofuran 0/50 ...
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TR-507: Vanadium Pentoxide (CASRN 1314-62-1) in F344/N Rats and... 6.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr507.pdf
.../49 Molybdenum trioxide 0/50 0/50 0/50 Nitromethane 1/50 0/50 1/50 Ozone 1/50 1/50 2/50 .../50 Molybdenum trioxide 0/50 0/50 0/50 Nitromethane 0/50 1/50 1/50 Ozone 0/50 0/50 0/50 ...
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TR-552: Propargyl Alcohol (CASRN 107-19-7) in F344/N Rats and... 3.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr552.pdf
... 1993), chloroprene (NTP, 1998), ethylene oxide (NTP, 1987), and nitromethane (NTP, 1997). ... Toxicology and Carcinogenesis Studies of Nitromethane (CAS No. 75-52-5) in F344/N Rats and ...