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TR-433: Tricresyl Phosphate (CASRN 1330-78-5) in F344/N Rats... 24.1MB
https://ntp.niehs.nih.gov/go/tr433
NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 433 TOXICOLOGY AND CARCINOGENESIS STUDIES OF TRICRESYL PHOSPHATE (CAS NO. 1330-78-5) IN F344/N RATS AND B6C3F, MICE (GAVAGE ...
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TR-602: Isomeric Mixture of Tris(chloropropyl) Phosphate Administered... 8.0MB
https://ntp.niehs.nih.gov/sites/default/files/2023-06/tr602_508.pdf
NTP TechNical RePoRT oN The Toxicology aNd caRciNogeNesis sTudies of aN isomeRic mixTuRe of TRis(chloRoPRoPyl) PhosPhaTe admiNisTeRed iN feed To sPRague dawley (hsd:sPRague dawley ...
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TR-391: Tris(2-chloroethyl) Phosphate (CASRN 115-96-8) in F344... 11.0MB
https://ntp.niehs.nih.gov/go/tr391
1 TOXICOLOGY AND CARCINOGENESIS STUDIES OF TRIS(2-CHLOROETHYL)PHOSPHATE (CAS NO. 115-96-8) IN F344/N RATS ANDB6C3Fl MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN ...
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TR-294: Chlorinated Trisodium Phosphate (CASRN 56802-99-4) in... 6.5MB
https://ntp.niehs.nih.gov/go/tr294
National Toxicology Program Technical Report Series No. 294 TOXICOLOGY AND CARCINOGENESIS STUDIES OF CHLORINATED TRISODIUM PHOSPHATE (CAS NO. 56802-99-4) IN B6C3F1 MICE (GAVAGE ...
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DART-01: Prenatal Development Studies of Tris(chloropropyl) Phosphate... 911KB
https://ntp.niehs.nih.gov/go/dart01
NTP DeveloPmeNTal aND RePRoDucTive ToxiciTy TechNical RePoRT oN The PReNaTal DeveloPmeNT STuDieS of TRiS(chloRoPRoPyl) PhoSPhaTe (caSRN 13674-84-5) iN SPRague Dawley (hSD:SPRague ...
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RoC Profile: Tris(2,3-dibromopropyl) Phosphate; 15th RoC 2021 132KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/tris_dibromopropyl_phosphate.pdf
Tris(2,3-dibromopropyl) Phosphate CAS No. 126-72-7 Reasonably anticipated to be a human carcinogen First listed in the Second Annual Report on Carcinogens (1981) Also known as TRIS ...
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Abstract for TR-433 64KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr433
3abs Abstract for TR-433 Toxicology and Carcinogenesis Studies of Tricresyl Phosphate in F344/N Rats and B6C3F1 Mice (Gavage and Feed Studies) CASRN: 1330-78-5 Chemical Formula: ...
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RR-08: In Vivo Repeat Dose Biological Potency Study of Triphenyl... 1.5MB
https://ntp.niehs.nih.gov/go/rr08
IN VIVo RePeaT Dose BIologIcal PoTeNcy sTuDy of TRIPheNyl PhosPhaTe (cas No. 115-86-6) IN Male sPRague Dawley RaTs (hsD: sPRague Dawley sD) (gaVage sTuDIes) NTP RR 8 DECEMBER 2018 ...
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TR-076: Tris (2,3-Dibromopropyl) Phosphate (CASRN 126-72-7) 4.1MB
https://ntp.niehs.nih.gov/go/tr076
Institute CARCINOGENESIS Technical Report Series No. 76 BIOASSAY OF TRIS (2,3-DIBROMOPROPYL) PHOSPHATE FOR POSSIBLE CARCINOGENICITY CAS No. 126-72-7 NCI-CG-TR-76 U.S. DEPARTMENT OF ...
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tris(2,3-Dibromopropyl) phosphate: Target Organs and Levels of... 52KB
https://ntp.niehs.nih.gov/data/tr/000s/tr076levels
4 tris(2,3-Dibromopropyl) phosphate: Target Organs and Levels of Evidence for TR-076 Bioassay of Tris (2,3-Dibromopropyl) Phosphate for Possible Carcinogenicity (CASRN 126-72-7) ...
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Nomination Summary for Flame retardants (N20608) 47KB
https://ntp.niehs.nih.gov/go/nm-n20608
Nomination Summary for Flame retardants (N20608) Nominated Substances: Antimony Trioxide, tert-Butylphenyl Diphenyl Phosphate, Decabromodiphenyl Ether, 2-Ethylhexyl Diphenyl ...
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Abstract for TR-602 69KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr602
2abs Abstract for TR-602 Toxicology and Carcinogenesis Studies of an Isomeric Mixture of Tris(chloropropyl) Phosphate Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley SD) ...
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Abstract for TR-391 59KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr391
1abs Abstract for TR-391 Toxicology and Carcinogenesis Studies of Tris(2-chloroethyl) Phosphate in F344/N Rats and B6C3F1 Mice (Gavage Studies) CASRN: 115-96-8 Chemical Formula: ...
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Abstract for DART-01 68KB
https://ntp.niehs.nih.gov/publications/reports/dart/dart01
1abs Abstract for DART-01 Prenatal Development Studies of Tris(chloropropyl) Phosphate in Sprague Dawley (Hsd:Sprague Dawley SD) Rats (Gavage Studies) CASRN: 13674-84-5 Chemical ...
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Abstract for TR-294 57KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr294
94abs Abstract for TR-294 Toxicology and Carcinogenesis Studies of Chlorinated Trisodium Phosphate in B6C3F1 Mice (Gavage Studies) CASRN: 56802-99-4 Chemical Formula: ...
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Abstract for RR-08 56KB
https://ntp.niehs.nih.gov/publications/reports/rr/rr08
8abs Abstract for RR-08 In Vivo Repeat Dose Biological Potency Study of Triphenyl Phosphate in Male Sprague Dawley Rats (Hsd: Sprague Dawley SD) (Gavage Studies) CASRN: 115-86-6 ...
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Abstract for TR-76 57KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr076
6abs Abstract for TR-76 Bioassay of Tris (2,3-Dibromopropyl) Phosphate for Possible Carcinogenicity CASRN: 126-72-7 Chemical Formula: C9H15Br6O4P Molecular Weight: 697.6115 ...
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Peer Review Report: Draft NTP Technical Reports on Prenatal Developmen... 242KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2019/july/peerreviewtrprp20190731_508.pdf
National Toxicology Program Peer Review of the Draft NTP Technical Reports on Prenatal Developmental Toxicity Studies for: Tris(chloropropyl) Phosphate, 4-Methylcyclohexanemethanol...
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Abstract for RACB84114 57KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb84114
4abs Abstract for RACB84114 Tricresyl Phosphate Reproduction and Fertility Assessment in CD-1 Mice When Administered In Feed CASRN: 1330-78-5 Chemical Formula: C21H21O4P Molecular ...
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Target Organs and Levels of Evidence for TR-433 51KB
https://ntp.niehs.nih.gov/data/tr/400s/tr433levels
6 Target Organs and Levels of Evidence for TR-433 Toxicology and Carcinogenesis Studies of Tricresyl Phosphate (CASRN 1330-78-5) in F344/N Rats and B6C3F1 Mice (Gavage and Feed ...
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RoC Protocol: Organohalogen Flame Retardants; Jan. 31, 2025 662KB
https://ntp.niehs.nih.gov/sites/default/files/2025-03/organohalogen_flame_retardants_508.pdf
Protocol for the Cancer Hazard Evaluation of Organohalogen Flame Retardants: Human Cancer and Experimental Animal Cancer Studies Report on Carcinogens Monograph January 31, 2025 ...
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Agenda: TRPRP; July 31, 2019 283KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2019/july/agendatrprp20190731_508.pdf
Revised June 3, 2019 1 Wednesday, July 31, 2019 8:30 a.m. - approximately 5:00 p.m. EDT (meeting may end sooner or go longer) Breaks and lunch will be taken at the discretion of ...
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Target Organs and Levels of Evidence for TR-294 50KB
https://ntp.niehs.nih.gov/data/tr/200s/tr294levels
8 Target Organs and Levels of Evidence for TR-294 Toxicology and Carcinogenesis Studies of Chlorinated Trisodium Phosphate (CASRN 56802-99-4) in B6C3F1 Mice (Gavage Studies) ...
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Target Organs and Levels of Evidence for TR-391 53KB
https://ntp.niehs.nih.gov/data/tr/300s/tr391levels
0 Target Organs and Levels of Evidence for TR-391 Toxicology and Carcinogenesis Studies of Tris(2-chloroethyl) Phosphate (CASRN 115-96-8) in F344/N Rats and B6C3F1 Mice (Gavage ...
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Abstract for TR-274 57KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr274
4abs Abstract for TR-274 Toxicology and Carcinogenesis Studies of Tris(2-ethylhexyl)phosphate In F344/N Rats and B6C3F1 Mice (Gavage Studies) CASRN: 78-42-2 Chemical Formula: ...
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RoC Profile: Lead and Lead Compounds; 15th RoC 2021 190KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/lead.pdf
Lead and Lead Compounds CAS No. 7439-92-1 (Lead) No separate CAS No. assigned for lead compounds as a class Reasonably anticipated to be human carcinogens First listed in the ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
9433 Conclusion by Sex/Species Report No. Peer Review Date/Target Organs Substance Name CASRN Male Rats Female Rats Male Mice Female Mice TR-604 11/01/22 Triclosan 3380-34-5 SE ...
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TR-342: Dichlorvos (CASRN 62-73-7) in F344/N Rats and B6C3F1... 29.4MB
https://ntp.niehs.nih.gov/go/tr342
2 TOXICOLOGY AND CARCINOGENESIS STUDIES OF DICHLORVOS (CAS NO. 62-73-7) IN F344/N RATS AND B6C3Ft MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health ...
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OPFR Prioritization Using the Developmental Neurotoxicity In... 2.0MB
https://ntp.niehs.nih.gov/sites/default/files/2024-03/SOT2024-Oyetade-poster.pdf
Chemicals Assessed in the Case Study Chemical Type Chemical Name Chemical ID Structure Classic BFR 2,2'4,4'- tetrabromodiphenyl ether BDE-47 3,3',5,5'- tetrabromobisphenol A TBBPA ...
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TR-400: 2,3-Dibromo-1-Propanol (CASRN 96-13-9) in F344/N Rats... 11.3MB
https://ntp.niehs.nih.gov/go/tr400
400 TOXICOLOGY AND CARCINOGENESIS STUDIES OF 2,3-DIBROMO-l-PROPANOL (CAS NO. 96-13-9) IN F344/N RATS AND B6C3Fl MICE (DERMAL STUDIES) US. DEPARTMENT OF HEALTH AND HUMAN SERVICES ...
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Abstract for TR-400 62KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr400
0abs Abstract for TR-400 Toxicology and Carcinogenesis Studies of 2,3-Dibromo-1-Propanol in F344/N Rats and B6C3F1 Mice (Dermal Studies) CASRN: 96-13-9 Chemical Formula: C3H6Br2 O ...
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NIEHS-05 | National Institute of Environmental Health Sciences 394KB
https://www.niehs.nih.gov/research/atniehs/dtt/assoc/reports/niehs-05
5 Close the left navigation NIEHS Report on the In Vivo Repeat Dose Biological Potency Study of Isopropylated Phenol Phosphate (CASRN 68937-417) in Male Sprague Dawley (Hsd:Sprague ...
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NIEHS-06 | National Institute of Environmental Health Sciences 394KB
https://www.niehs.nih.gov/research/atniehs/dtt/assoc/reports/niehs-06
6 Close the left navigation NIEHS Report on the In Vivo Repeat Dose Biological Potency Study of Tricresyl Phosphate (CASRN 1330-78-5) in Male Sprague Dawley (Hsd:Sprague Dawley® ...
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Technical Reports 858KB
https://ntp.niehs.nih.gov/publications/reports/tr
TR-604 PDF (1.2 MB) Toxicology and Carcinogenesis Study of Triclosan (CASRN 3380-34-5) Administered Dermally to B6C3F1/N Mice 2024 Technical Report TR-603 PDF (3.02 MB) Toxicology ...
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NIEHS-02 | National Institute of Environmental Health Sciences 394KB
https://www.niehs.nih.gov/research/atniehs/dtt/assoc/reports/niehs-02
2 Close the left navigation NIEHS Report on the In Vivo Repeat Dose Biological Potency Study of 2-Ethylhexyl Diphenyl Phosphate (CASRN 1241-94-7) in Male Sprague Dawley ...
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NIEHS-03 | National Institute of Environmental Health Sciences 394KB
https://www.niehs.nih.gov/research/atniehs/dtt/assoc/reports/niehs-03
3 Close the left navigation NIEHS Report on the In Vivo Repeat Dose Biological Potency Study of tert-Butylphenyl Diphenyl Phosphate (CASRN 56803-37-3) in Male Sprague Dawley ...
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NIEHS-04 | National Institute of Environmental Health Sciences 394KB
https://www.niehs.nih.gov/research/atniehs/dtt/assoc/reports/niehs-04
4 Close the left navigation NIEHS Report on the In Vivo Repeat Dose Biological Potency Study of Isodecyl Diphenyl Phosphate (CASRN 29761-21-5) in Male Sprague Dawley (Hsd:Sprague ...
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TR-455: Codeine (CASRN 76-57-3) in F344 Rats and B6C3F1Mice ... 15.2MB
https://ntp.niehs.nih.gov/go/tr455
NATION& TOXICOLOGY PROGRAM Technical Report Series No. 455 TOXICOLOGY A N D CARCINOGENESIS STUDIES OF CODEINE (CAS NO. 76-57-3) . - . ~. . IN F344/NRATS AND B6C3Fl MICE (FEED ...
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NTP Synergistic Science: 2025 8.1MB
https://ntp.niehs.nih.gov/go/synergistic-science
Publication: August 2025 Table of Contents p. 2 --- Letter from the NTP Director p. 3 1.0. About NTP p. 4 1.1. NTP Organization p. 6 1.2. NTP Operations p. 7 1.3. Recent Events and ...
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Abstract for TER91021 55KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter91021
1abs Abstract for TER91021 Developmental Toxicity of Naphthalene in New Zealand White Rabbits CASRN: 91-20-3 Chemical Formula: C10H8 Molecular Weight: 128.173 Report Date: July ...
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OPFR Prioritization using the Developmental Neurotoxicity In... 140KB
https://ntp.niehs.nih.gov/sites/default/files/2024-01/Oyetade-SOT_2024_abstract-508.pdf
Oyetade et al. - Applying the DNT In Vitro Test Battery to Prioritization November 2023 NICEATM Abstract: SOT 2024 Annual Meeting OPFR Prioritization using the Developmental ...
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IATA Case Study for DNT (SACATM 2024 presentation) 1.2MB
https://ntp.niehs.nih.gov/sites/default/files/2024-10/3-2_Hogberg_SACATM2024_508.pdf
National Institutes of Health . U.S. Department of Health and Human Services Integrated Approaches to Testing and Assessment (IATA) Case Study for DNT Helena Hogberg NICEATM SACATM ...
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TR-508: Riddelliine (CASRN 23246-96-0) in F344/N Rats and B6C3F1... 3.1MB
https://ntp.niehs.nih.gov/go/tr508
NTP TECHNICAL REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF RIDDELLIINE (CAS NO. 23246-96-0) IN F344/N RATS AND B6C3F 1 MICE (GAVAGE STUDIES) NTP TR 508 MAY 2003 NTP ...
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Actions: TRPRP; July 31, 2019 147KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2019/july/actiontrprp20190731_508.pdf
1 Actions on the Draft NTP Technical Reports Peer Review on July 31, 2019 The NTP convened the NTP Technical Reports Peer Review Panel ("the Panel") on July 31, 2019, to peer ...
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Target Organs and Levels of Evidence for TR-602 55KB
https://ntp.niehs.nih.gov/data/tr/600s/tr602levels
021 Target Organs and Levels of Evidence for TR-602 TCPP is produced as a mixture of four isomers and all NTP studies have utilized a procured isomeric mixture. Herein, TCPP is ...
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Abstract for TR-342 57KB
https://ntp.niehs.nih.gov/publications/reports/tr/tr342
2abs Abstract for TR-342 Toxicology and Carcinogenesis Studies of Dichlorvos in F344/N Rats and B6C3F1 Mice (Gavage Studies) CASRN: 62-73-7 Chemical Formula: C4H7Cl2PO4 Molecular ...
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Developmental Neurotoxicity Assessment Using In Vitro Assays 6.8MB
https://ntp.niehs.nih.gov/iccvam/meetings/commprac-2022/20220125-iccvam-cop-hogberg-508.pdf
t'e\ NTP _ _ National Toxicology Program Developmental Neurotoxicity Assessment Using In Vitro Assays Helena Hogberg Division of the NTP, National Institute of Environmental Health ...
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Mechanistic and Other Relevant Data; Amy Wang; RoC; Jan. 24,... 1.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2018/january/presentations/mechanistic_508.pdf
Mechanistic and Other Relevant Data Amy Wang, PhD Office of the Report on Carcinogens National Institute of Environmental Health Sciences January 24, 2018 Draft RoC Monograph on ...
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Reports and Publications | National Institute of Environmental... 415KB
https://www.niehs.nih.gov/research/atniehs/dtt/assoc/reports
Reports and Publications Close the left navigation NTP Logo Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership ...
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TR-287: Dimethyl Hydrogen Phosphite (CASRN 868-85-9) in F344... 9.9MB
https://ntp.niehs.nih.gov/go/tr287
7 TOXICOLOGY AND CARCINOGENESIS STUDIES OF DIMETHYL HYDROGEN PHOSPHITE (CAS NO. 868-85-9) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN ...