TR-393: Sodium Fluoride (CASRN 7681-49-4)in F344/N Rats and B6C3F1Mice... 21.9MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr393.pdf

NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 393 TOXICOLOGY AND CARCINOGENESIS STUDIES OF SODIUM FLUORIDE (CAS NO. 7681-49-4) IN F344/N RATS AND B6C3Fl MICE (DRINKING ...

Comment: Fluoride; George R. Shepley and Raymond A. Cohlmia;... 537KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/publiccomm/shepley-cohlmia20230428_bsc_508.pdf

April 28, 2023 Kathleen M. Gray, Ph.D. Chair, NTP Board of Scientific Counselors c/o Office of Policy, Review, and Outreach Division of Translational Toxicology National Institute ...

NTP Working Group Report: Draft State of the Science Monograph... 20.1MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/wgrptbsc20230400.pdf

NTP Board of Scientific Counselors Working Group Report on the Draft State of the Science Monograph and the Draft Meta-Analysis Manuscript on Fluoride April 2023 NTP BSC Working ...

NTP Working Group Report: Draft State of the Science Monograph... 9.5MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may16/meeting_materials/wgrptbsc20230400_interimver_508.pdf

PLEASE NOTE: On May 4, 2023, the NTP Board of Scientific Counselors voted to accept the report in full, with the exception of text for 8.P (page 323) related to an IQ statistic ...

NTP Board of Scientific Counselors Working Group Report on the... 9.4MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may16/bsc_wg_report_final_version_bsc_approved051623_508.pdf

NTP Board of Scientific Counselors Working Group Report on the Draft State of the Science Monograph and the Draft Meta-Analysis Manuscript on Fluoride Final Report: Approved by the ...

Literature Search Results: Systematic Review of Fluoride Exposure... 768KB

https://ntp.niehs.nih.gov/ntp/ohat/fluoride/literature_results20200916_508.pdf

LITERATURE SEARCH RESULTS FOR THE SYSTEMATIC REVIEW OF FLUORIDE EXPOSURE AND NEURODEVELOPMENTAL AND COGNITIVE HEALTH EFFECTS September 16, 2020 Office of Health Assessment and ...

Documents Provided to the NTP Board of Scientific Counselors... 55.2MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/fluoride/documents_provided_bsc_wg_031523.pdf

DRAFT NTP Monograph on the State of the Science Concerning Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects: A Systematic Review NTP Monograph 08 September ...

Comment: Fluoride; Bill Osmunson; Washington Action for Safe... 1.9MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/publiccomm/osmunson20230428_bsc_508.pdf

To The National Toxicology Board of Scientific Counselors Regarding: Draft NTP Monograph on the State of the Science Concerning Fluoride Exposure and Neurodevelopmental and ...

Comment: Fluoride; Paul Connett; Fluoride Action Network; BSC... 2.7MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/publiccomm/connett20230428_bsc_508.pdf

Paul Connett, PhD Former Director, Fluoride Action Network (2000-2022) Paul Connett's statement for the BSC meeting May 4, 2023 A ringside view of the battle between science and ...

RR-01: Systematic Literature Review on the Effects of Fluoride... 7.2MB

https://ntp.niehs.nih.gov/ntp/results/pubs/rr/reports/rr01_508.pdf

NTP ReseaRch RePoRT oN sysTemaTic LiTeRaTuRe Review oN The effecTs of fLuoRide oN LeaRNiNg aNd memoRy iN aNimaL sTudies NTP RR 1 JULY 2016 NTP Research Report on Systematic ...

NTP Protocol: Systematic Review of Effects of Fluoride Exposure... 2.1MB

https://ntp.niehs.nih.gov/ntp/ohat/fluoride/ntpprotocol_revised20200916_508.pdf

PROTOCOL FOR SYSTEMATIC REVIEW OF EFFECTS OF FLUORIDE EXPOSURE ON NEURODEVELOPMENT Project Leader: Kyla Taylor, PhD, Office of Health Assessment and Translation (OHAT), DNTP ...

Comment: Fluoride; Bill Osmunson; Washington Action for Safe... 547KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/publiccomm/osmunson20230510_bsc_508.pdf

Presented to the National Toxicology Program (NTP) A Response to the Board of Scientific Counselors (BSC) submission by American Association for Dental Oral and Craniofacial ...

Protocol for Systematic Review of Effects of Fluoride Exposure... 2.2MB

https://ntp.niehs.nih.gov/ntp/ohat/fluoride/protocol_fluoridejune2017_508.pdf

Protocol for Systematic Review of Effects of Fluoride Exposure on Neurodevelopment June 2017 Office of Health Assessment and Translation Division of the National Toxicology ...

Protocol for Systematic Review of Effects of Fluoride Exposure... 1.9MB

https://ntp.niehs.nih.gov/ntp/ohat/fluoride/protocol_fluoridemay2019_508.pdf

PROTOCOL FOR SYSTEMATIC REVIEW OF EFFECTS OF FLUORIDE EXPOSURE ON NEURODEVELOPMENT Project Leader: Kyla Taylor, PhD, Office of Health Assessment and Translation (OHAT), DNTP ...

Comment: Fluoride; Christopher H. Fox and Alexandre Vieira; AADOCR... 405KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/publiccomm/fox-vieira20230428_bsc_508.pdf

April 28, 2023 Kathleen M. Gray, Ph.D. Chair, NTP Board of Scientific Counselors c/o Office of Policy, Review, and Outreach National Institute of Environmental Health Sciences ...

Comment: Fluoride; Mark Moss; Private Citizen; BSC; May 4, 2023 208KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/publiccomm/moss20230427_bsc_508.pdf

Mark Moss 1. A general concern is that the studies that are cited in the NTP review for the confidence conclusions are of low quality and have high risk for bias. We have conducted ...

Comment: Fluoride; Chris Neurath; American Environmental Health... 3.4MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/publiccomm/neurath20230429_bsc_508.pdf

The finding's of the NTP's 6-year fluoride neurotoxicity evaluation Chris Neurath Science Director American Environmental Health Studies Project May 4, 2023 1 What did the NTP ...

Proposed NTP Evaluation on Fluoride Exposure and Potential for... 1012KB

https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2015/december/meetingmaterial/fluoride_508.pdf

sc Proposed NTP Evaluation on Fluoride Exposure and Potential for Developmental Neurobehavioral Effects November 19, 2015 Office of Health Assessment and Translation (OHAT) ...

Comment: Fluoride; Howard Pollick; American Dental Assocation... 165KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/publiccomm/pollick20230504_bsc_508.pdf

W a s h i n g t o n O f f i c e : 1 1 1 1 1 4 t h S t r e e t N W W a s h i n g t o n D C 2 0 0 0 5 ( 2 0 2 ) 8 9 8 - 2 4 0 0 STATEMENT OF THE AMERICAN DENTAL ASSOCIATION TO THE ...

RoC Background Document: Vinyl Fluoride; Jan. 20-21, 2000 468KB

https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/vf_no_appendices_508.pdf

Vinyl Fluoride Meeting of the NTP Board of Scientific Counselors Report on Carcinogens Subcommittee Prepared for the: U.S. Department of Health and Human Services Public Health ...

Fluoride: Assessment for Developmental Neurotoxicity 87KB

https://ntp.niehs.nih.gov/whatwestudy/assessments/noncancer/ongoing/fluoride

785076 Fluoride: Assessment for Developmental Neurotoxicity Running water from faucet Topic Overview CASRN: 16984-48-8 Status: Topic under evaluation Background Information The ...

Comment: Concerning Fluoride Exposure and Neurodevelopmental... 228KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/presentations/08_osmunson_bsc_508.pdf

NTP Board of Scientific Counselors Draft Monograph on the State of Science vs. Meta-Analysis Concerning Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects: A ...

Comment: Fluoride; Brian R. Berridge; B2 Pathology Solutions... 96KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/publiccomm/berridge20230428_bsc_508.pdf

B2 Pathology Solutions LLC Brian R. Berridge, DVM, PhD, DACVP | PRINCIPAL CONSULTANT 28 April 2023 Kathleen M. Gray, PhD Chair, NTP Board of Scientific Counselors National ...

Comment: Fluoride; John F. Mueller Jr.; Private Citizen; BSC... 1.9MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/publiccomm/mueller20230503_bsc_508.pdf

John F. Mueller Jr. Private Citizen 05/03/2023 I am writing with the understanding that a public meeting to be held on May 4 th will be addressing the reported science of ...

Comment: Fluoride; Christopher Neurath; American Environmental... 188KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may16/publiccomm/neurath20230516_bsc_508.pdf

American Environmental Health Studies Project May 15, 2023 National Toxicology Program (NTP) Board of Scientific Counselors (BSC) RE: Correction to BSC WG report Dear Chairperson ...

Abstract for TR-393 66KB

https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr393

3abs Abstract for TR-393 Toxicology and Carcinogenesis Studies of Sodium Fluoride in F344/N Rats and B6C3F1 Mice (Drinking Water Studies) CASRN: 7681-49-4 Chemical Formula: NaF ...

Presentation: NTP Evaluation of Fluoride Exposure and Potential... 291KB

https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2015/december/presentations/fluoride20151202_508.pdf

NTP Evaluation of Fluoride Exposure and Potential for Developmental Neurobehavioral Effects Kristina Thayer, PhD Office of Health Assessment and Translation (OHAT) National ...

Comment: The Neurotoxicity of Fluoride: A Ringside View of the... 497KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/presentations/07_connett_bsc_508.pdf

The Neurotoxicity of Fluoride: A Ringside View of the Politics versus Science Paul Connett, PhD Former Director, Fluoride Action Network Testimony before the BSC May 4, 2023 ...

Comment: The Finding's of the NTP's 6-year Fluoride Neurotoxicity... 2.4MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/presentations/04_neurath_bsc_508.pdf

The finding's of the NTP's 6-year fluoride neurotoxicity evaluation Chris Neurath Science Director American Environmental Health Studies Project May 4, 2023 1 What did the NTP ...

Response to Comments: NASEM Peer Review of Draft NTP Monograph... 280KB

https://ntp.niehs.nih.gov/ntp/nasem/response202009.pdf

This document is distributed solely to support pre-dissemination peer review and does not represent and should not be construed to represent any NTP determination or policy. 1 ...

NTP BSC Working Group Report on the Draft State of the Science... 1.1MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/presentations/ntp_bsc_wg_report_presentation_508.pdf

NTP Board of Scientific Counselors (BSC) Working Group Report on the Draft State of the Science Monograph and the Draft Meta-Analysis Manuscript on Fluoride David L. Eaton, PhD, ...

Comment: Scientific Integrity and a Fluoride Hazard to Public... 105KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/publiccomm/hirzy20230427_bsc_508.pdf

John William Hirzy National Federation of Federal Employees Statement of J. William Hirzy, Ph.D. Re8red Senior Scien8st USEPA Office of Pes8cides and Toxic Substances and Charter ...

Comment: Scientific Integrity and a Fluoride Hazard to Public... 89KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/presentations/06_hirzy_bsc_508.pdf

Scientific Integrity and a Fluoride Hazard to Public Health Slides of J. W. Hirzy "You Can't Fool Mother Nature" . That was Richard Feynman's succinct comment describing the 1986 ...

Abstract for TER91033 62KB

https://ntp.niehs.nih.gov/publications/abstracts/dev/ter91033

3abs Abstract for TER91033 Developmental Toxicity of Sodium Fluoride in New Zealand White Rabbits CASRN: 7681-49-4 Chemical Formula: NaF Molecular Weight: 41.988 Report Date: ...

Comment: National Toxicology Program Board of Scientific Counselors... 328KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/publiccomm/kall20230428_bsc_508.pdf

Jack Kall 1 International Academy of Oral Medicine and Toxicology IAOMT Oral Comments for NTP BSC Hello, I am Dr. Jack Kall, a practicing dentist for 46 years. I am the Executive ...

Tooth, Odontoblast - Degeneration - Nonneoplastic Lesion Atlas 288KB

https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/tooth/Odontoblast-Degeneration

Fluoride toxicity is the most well characterized cause of odontoblast degeneration (Figure 1 image opens in a pop-up window and Figure 2 image opens in a pop-up window , arrows). ...

RoC Profile: Vinyl Halides (Selected); 15th RoC 2021 199KB

https://ntp.niehs.nih.gov/ntp/roc/content/profiles/vinylhalides.pdf

Vinyl Halides (Selected) Introduction Vinyl bromide, vinyl chloride, and vinyl fluoride belong to a class of structurally related chemicals referred to as "simple vinyl halides" or ...

Comment: National Toxicology Program Board of Scientific Counselors... 150KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/publiccomm/maas20230427_bsc_508.pdf

1 William R Maas Subject: Flawed Measurement of IQ Outcome in the MIREC Studies I am writing to express concerns about studies relying on the Maternal-Infant Research on ...

Abstract for TER91022 62KB

https://ntp.niehs.nih.gov/publications/abstracts/dev/ter91022

2abs Abstract for TER91022 Developmental Toxicity of Sodium Fluoride in Sprague Dawley CD Rats CASRN: 7681-49-4 Chemical Formula: NaF Molecular Weight: 41.988 Report Date: ...

Comment: Show me the Science; Jack Kall, International Academy... 945KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/presentations/09_kall_bsc_508.pdf

SHOW ME THE SCIENCE Our 1500 members are dentists, physicians and researchers who investigate and communicate safe, science-based treatments to promote whole body health. Jack ...

Comment: National Toxicological Program (NTP) Board of Scientific... 1.1MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/presentations/05_kennedy_bsc_508.pdf

National Toxicological Program (NTP) Board of Scientific Counselors (BSC) David Kennedy DDS For The Preventative Dental Health Association (NTP) Board of Scientific Counselors ...

Minutes: BSC; Dec. 1-2, 2015 1.6MB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2015/december/bsc_dec2015_minutes_508.pdf

Summary Minutes NTP Board of Scientific Counselors December 1 - 2, 2015 Summary Minutes December 1 - 2, 2015 NTP Board of Scientific Counselors 1 Table of Contents I. Frequently ...

Target Organs and Levels of Evidence for TR-393 57KB

https://ntp.niehs.nih.gov/data/tr/300s/tr393levels

4 Target Organs and Levels of Evidence for TR-393 Toxicology and Carcinogenesis Studies of Sodium Fluoride (CASRN 7681-49-4) in F344/N Rats and B6C3F1 Mice (Drinking WaterStudies) ...

Minutes: BSC; May 4 and 16, 2023 361KB

https://ntp.niehs.nih.gov/sites/default/files/2023-09/minutesbsc20230504and16_508.pdf

Toxicology Program Board of Scientific Counselors May 4 and 16, 2023 National Institute of Environmental Health Sciences Research Triangle Park, NC Summary Minutes 1 1 The summary ...

NTP BSC Chair transmittal letter, May 18, 2023: BSC; May 16,... 121KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may16/bsc_chair_transmittal_letter_051823_signed_508.pdf

May 18, 2023 Richard Woychik, Ph.D. Director National Institute of Environmental Health Sciences and National Toxicology Program National Institute of Environmental Health ...

Table of Contents - Documents Provided to the NTP Board of Scientific... 133KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/fluoride/toc_documents_provided_bsc_wg_031523.pdf

TABLE OF CONTENTS Documents provided to the NTP Board of Scientific Counselors for review and deliberation regarding the DRAFT NTP Monograph on Fluoride and DRAFT Meta-Analysis ...

RoC Background Document: Tetrafluoroethylene; March 1999 4.5MB

https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/tetrafluoroethylene1.pdf

for TETRAFLUOROETHYLENE FINAL MARCH 1999 Prepared for the October 30-31, 1997, Meeting of the Report on Carcinogens Subcommittee of the NTP Board of Scientific Counselors Prepared ...

Comment: Statement to the NTP Board of Scientific Counselors... 238KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/presentations/10_pollick_bsc_508.pdf

Presented by Howard Pollick, B.D.S., M.P.H. Professor of Preventive and Restorative Dental Sciences University of California San Francisco School Of Dentistry May 4, 2023 Statement ...

Tooth, Dentin - Basophilic Granules - Nonneoplastic Lesion Atlas 286KB

https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/tooth/Dentin-BasophilicGranules

Basophilic granules in the dentin (Figure 1 image opens in a pop-up window and Figure 2 image opens in a pop-up window ) are rarely seen in the NTP studies. They are small, round, ...

Comment: Testimony for NTP Board of Scientific Counselors; Rick... 166KB

https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2023/may/publiccomm/north20230427_bsc_508.pdf

Rick North Private Citizen TESTIMONY FOR NTP BOARD OF SCIENTIFIC COUNSELORS - MAY 4, 2023 My name is Rick North. My background is in non-profit health management, 21 years for the ...