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TR-385: Methyl Bromide (CASRN 74-83-9) in B6C3F1Mice (Inhalation... 7.3MB
https://ntp.niehs.nih.gov/go/tr385
NATIONAL TOXICOLOGY PROGRAM Technical Report Series No. 385 TOXICOLOGY AND CARCINOGENESIS STUDIES OF METHYL BROMIDE (CAS NO. 74-83-9) IN B6C3F 1 MICE (INHALATION STUDIES) U.S. ...
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GMM-07: Genetically Modified Model Report on Allyl Bromide (Dermal... 1.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm07_508.pdf
allyl BRoMide (caSRN 106-95-6) iN GeNeTically Modified (fVB TG.ac heMizyGouS) Mice aNd caRciNoGeNiciTy STudieS of allyl BRoMide iN GeNeTically Modified [B6.129-TRP53 TM1BRd (N5) ...
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RoC Background Document: Vinyl Bromide; Jan. 20-21, 2000 220KB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/vb_no_appendices_508.pdf
FINAL Report on Carcinogens Background Document for Vinyl Bromide Meeting of the NTP Board of Scientific Counselors Report on Carcinogens Subcommittee Prepared for the: U.S. ...
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Allyl bromide: Target Organs and Levels of Evidence for GMM-07 62KB
https://ntp.niehs.nih.gov/data/gmm/gmm07levels
2 Allyl bromide: Target Organs and Levels of Evidence for GMM-07 Toxicology Studies of Allyl Bromide (CASRN 106-95-6) in Genetically Modified (FVB Tg.AC Hemizygous) Mice and ...
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Abstract for GMM-7 71KB
https://ntp.niehs.nih.gov/publications/reports/gmm/gmm07
7abs Abstract for GMM-7 Toxicology Studies of Allyl Bromide in Genetically Modified (FVB Tg.AC Hemizygous) Mice and Carcinogenicity Studies of Allyl Bromide in Genetically Modified ...
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Abstract for TR-385 65KB
https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr385
5abs Abstract for TR-385 Toxicology and Carcinogenesis Studies of Methyl Bromide in B6C3F1 Mice (Inhalation Studies) CASRN: 74-83-9 Chemical Formula: CH3Br Molecular Weight: 94.95 ...
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Abstract for RACB84067 61KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb84067
7abs Abstract for RACB84067 Propantheline Bromide: Reproduction and Fertility Assessment in CD-1 Mice When Administered in Feed CASRN: 50-34-0 Chemical Formula: C23H30NO3.Br ...
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RoC Profile: Vinyl Halides (Selected); 15th RoC 2021 199KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/vinylhalides.pdf
Vinyl Halides (Selected) Introduction Vinyl bromide, vinyl chloride, and vinyl fluoride belong to a class of structurally related chemicals referred to as "simple vinyl halides" or ...
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Target Organs and Levels of Evidence for TR-385 58KB
https://ntp.niehs.nih.gov/data/tr/300s/tr385levels
28 Target Organs and Levels of Evidence for TR-385 Toxicology and Carcinogenesis Studies of Methyl Bromide (CASRN 74-83-9) in B6C3F1 Mice (Inhalation Studies) Chemical (Study ...
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Abstract for GMM-6 79KB
https://ntp.niehs.nih.gov/publications/reports/gmm/gmm06
6abs Abstract for GMM-6 Toxicology Studies of Sodium Bromate in Genetically Modified (FVB Tg.AC Hemizygous) Mice (Dermal and Drinking Water Studies) and Carcinogenicity Studies of ...
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RoC Profile: 1-Bromopropane; 15th RoC 2021 194KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/bromopropane.pdf
1-Bromopropane CAS No. 106-94-5 Reasonably anticipated to be a human carcinogen First listed in the Thirteenth Report on Carcinogens (2014) Also known as n-propyl bromide C H 2 H 2 ...
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Minutes: BSC TRRS; Aug. 28, 2006 1.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2006/aug/trrs28aug2006mins_508.pdf
Contents Page Number Attendees...... 1 Peer Review Meeting ...
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Abstract for TR-583 81KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr583
3abs Abstract for TR-583 Toxicology Studies of Bromodichloroacetic Acid in F344/N Rats and B6C3F1/N Mice and Toxicology and Carcinogenesis Studies of Bromodichloroacetic Acid in ...
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Abstract for TR-532 68KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr532
2abs Abstract for TR-532 Toxicology and Carcinogenesis Studies of Bromodichloromethane in Male F344/N Rats and Female B6C3F1 Mice (Drinking Water Studies) CASRN: 75-27-4 Chemical ...
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Abstract for GMM-5 86KB
https://ntp.niehs.nih.gov/publications/reports/gmm/gmm05
5abs Abstract for GMM-5 Toxicology Studies of Bromodichloromethane in Genetically Modified (FVB Tg.AC Hemizygous) Mice (Dermal, Drinking Water, and Gavage Studies) and ...
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1-Bromopropane: Preliminary Literature Search Strategy and List... 639KB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/litsearchstrategy/1-bp-litsearch&references5oct2012_508.pdf
10/5/12 1-Bromopropane 1-Bromopropane: Preliminary Literature Search Strategy and List of References A. Preliminary literature search strategy This document identifies the data ...
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Nomination Background: Dibromoacetic acid (CASRN: 631-64-1) 266KB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/dibromoaceticacid_508.pdf
INFORMATION PROFILE FOR NIEHS NOMINATIONS OF CHEMICALS TO THE NATIONAL TOXICOLOGY PROGRAM Date: 6/27/96 Nominator: EPA Phone: 1-3440 Address: NIEHS CHEMICAL IDENTIFICATION Common ...
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RoC Monograph: 1-Bromopropane; September 2013 1.9MB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/monographs_final/1bromopropane_508.pdf
1-BRoMopRopane ROC MONOGRAPH 01 SEPTEMBER 2013 Report on Carcinogens Monograph on 1-Bromopropane RoC Monograph 01 September 2013 National Toxicology Program Public Health Service ...
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GMM-06: Genetically Modified Model Report on Sodium Bromate ... 1.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm06_508.pdf
SodiuM BRoMaTe (caSRN 7789-38-0) iN GeNeTically Modified (fVB TG.ac heMizyGouS) Mice (deRMal aNd dRiNkiNG WaTeR STudieS) aNd caRciNoGeNiciTy STudieS of SodiuM BRoMaTe iN ...
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Abstract for TR-445 77KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr445
5abs Abstract for TR-445 Toxicology and Carcinogenesis Studies of Scopolamine Hydrobromide Trihydrate in F344 Rats and B6C3F1 Mice (Gavage Studies) CASRN: 6533-68-2 Chemical ...
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CERHR Monograph: 1-Bromopropane 1.1MB
https://ntp.niehs.nih.gov/ntp/ohat/bromopropanes/1-bromopropane/1bp_monograph.pdf
Monograph on the Potential Human Reproductive and Developmental Effects of 1-Bromopropane October 2003 NIH Publication No. 04-4479 iii Table of Contents Preface ...
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CERHR Monograph: Potential Human Reproductive and Developmental... 1.0MB
https://ntp.niehs.nih.gov/ntp/ohat/bromopropanes/2-bromopropane/2bp_monograph.pdf
NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of 2-Bromopropane December 2003 NIH Publication No. 04-4480 Table of Contents Preface ...
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Abstract for TR-564 79KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr564
4abs Abstract for TR-564 Toxicology and Carcinogenesis Studies of 1-Bromopropane in F344/N Rats and B6C3F1 Mice (Inhalation Studies) CASRN: 106-94-5 Chemical Formula: C3H7Br ...
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RoC Review of 1-Bromopropane 71KB
https://ntp.niehs.nih.gov/whatwestudy/assessments/cancer/completed/bromopropane
717271 RoC Review of 1-Bromopropane Men's dress shirts prepared for dry cleaning Substance Overview CASRN: 106-94-5 Status: RoC: Reasonably anticipated to be a human carcinogen ...
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TR-445: Scopolamine Hydrobromide Trihydrate (CASRN 6533-68-2... 13.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr445.pdf
5 TOXICOLOGY AND CARCINOGENESIS STUDIES OF SCOPOLAMINE HYDROBROMIDE TRIHYDRATE (CAS NO.6533-68-2) IN F344/N RATSAND B6C3Fl MICE (GAVAGE STUDIES) US.DEPARTMENT OF HEALTH AND HUMAN ...
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TR-564: 1-Bromopropane (CASRN 106-94-5) in F344/N Rats and B6C3F1... 9.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr564.pdf
1-BROMOPROPANE (CAS NO. 106-94-5) IN F344/N RATS AND B6C3F1 MICE (INHALATION STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research triangle Park, NC 27709 August 2011 NTP TR ...
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RoC Concept:1-Bromopropane 268KB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/concepts/1-bp_concdocroc8-30-12_508.pdf
Report on Carcinogens (RoC) Concept: 1-Bromopropane Project Leader: Diane Spencer, MS, Office of the RoC (ORoC), DNTP, NIEHS 1. Rationale 1-Bromopropane (CASRN 106-94-5) is a ...
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Agenda: BSC TRRS; Aug. 28, 2006 109KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2006/aug/trrs28aug2006agenda_508.pdf
NATIONAL TOXICOLOGY PROGRAM BOARD OF SCIENTIFIC COUNSELORS Technical Reports Review Subcommittee Meeting Preliminary Agenda August 28, 2006 8:30 a.m. - 5:00 p.m. National ...
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Abstract for TR-210 64KB
https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr210
10abs Abstract for TR-210 Carcinogenesis Bioassay of 1,2-Dibromoethane in F344 Rats and B6C3F1 Mice (Inhalation Study) CASRN: 106-93-4 Chemical Formula: C2H4Br2 Molecular Weight: ...
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RoC Background Document: Vinyl Fluoride; Jan. 20-21, 2000 468KB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/vf_no_appendices_508.pdf
Vinyl Fluoride Meeting of the NTP Board of Scientific Counselors Report on Carcinogens Subcommittee Prepared for the: U.S. Department of Health and Human Services Public Health ...
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Minutes: BSC TRRS; Nov. 19, 1990 1.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1990/nov/trrs19nov1990mins_508.pdf
N a t i o n a l T o x i c o l o g y Program Summary Minutes f rom Peer Review o f D r a f t T e c h n i c a l Reports o f Long-Term T o x i c o l o g y and C a r c i n o g e n e s ...
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Nomination Background: 1-Butyl-3-methylimidazolium chloride ... 1.5MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/ionic_liquids_508.pdf
Ionic Liquids 1-Butyl-3-methylimidazolium Chloride (CAS No. 79917-90-1) 1-Butyl-1-methylpyrrolidinium Chloride (CAS No. 479500-35-1) N-Butylpyridinium Chloride (CAS No. 1124-64-7) ...
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Revised Draft ROC Monograph: Haloacetic Acids; Oct. 30, 2017 4.2MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2017/july/haadraftmonograph20171030.pdf
This information is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally distributed by ...
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TR-532: Bromodichloromethane (CASRN 75-27-4) in Male F344/N Rats... 7.2MB
https://ntp.niehs.nih.gov/go/tr532
THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF BROMODICHLOROMETHANE (CAS NO. 75-27-4) IN MALE F344/N RATS AND FEMALE B6C3F 1 MICE (DRINKING WATER STUDIES) NATIONAL TOXICOLOGY PROGRAM ...
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Draft ROC Monograph: Haloacetic Acids; June 6, 2017 3.1MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2017/july/haadraftmonograph.pdf
Draft Report on Carcinogens Monograph on Haloacetic Acids Found as Water Disinfection By-Products Peer-Review Draft June 6, 2017 Office of the Report on Carcinogens Division of ...
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Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf
Guidance Document on Using In Vitro Data to Estimate In Vivo Starting Doses for Acute Toxicity Based on Recommendations from an International Workshop Organized by the Interagency ...
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Esophagus - Hyperplasia - Nonneoplastic Lesion Atlas 290KB
https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/esophagus/Hyperplasia
Hyperplasia of the mucosal epithelium is characterized by an increased number of epithelial cells and the absence of atypia. The epithelial cells may be of one or more epithelial ...
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Public Comment: Methyl isobutyl ketone; Steven Risotto; RoC;... 379KB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2013/publiccomm/risotto20131018_508.pdf
October 18, 2013 Dr. Ruth Lunn Director Office of the Report on Carcinogens National Toxicology Program National Institute for Environmental Health Sciences Research Triangle ...
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Esophagus - Hyperplasia 436KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/alimentary/esophagus/hyperpl/esophagus-hyperplasia-pdf-508.pdf
Esophagus - Hyperplasia Figure Legend: Figure 1 Esophagus, Epithelium - Hyperplasia in a female B6C3F1 mouse from a chronic study. There are rete peg-like structures and ...
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RoC Profile: Haloacetic Acids; 15th RoC 2021 382KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/haloacetic_acids.pdf
Report on Carcinogens, Fifteenth Edition National Toxicology Program, Department of Health and Human Services For Table of Contents, see home page: http://ntp.niehs.nih.gov/go/roc ...
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Historical Controls: Pathology Tables by All Routes/Vehicles... 224KB
https://ntp.niehs.nih.gov/ntp/historical_controls/historicalratesgmm_508.pdf
Historical control rates for NTP Tg.AC and p53 mice G. E. Kissling 1/31/08 Tg.AC Females, 6 months Trimethlolpropane triacrylate Pentaerythritol triacrylate Bromodichloromethane ...
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Report: International Workshop on In Vitro Methods for Assessing... 25.4MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf
Report of the International Workshop on In Vitro Methods for Assessing Acute Systemic Toxicity Results of an International Workshop Organized by the Interagency Coordinating ...
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Stomach, Forestomach, Epithelium - Hyperplasia, Atypical - Nonneoplast... 292KB
https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/stomach-forestomach/Epithelium-HyperplasiaAtypical
Some chemicals cause atypical hyperplasia of the forestomach that is characterized by hyperplasia and disorganization, abnormal keratinization, or the presence of abnormal cells ...
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Stomach, Forestomach, Epithelium - Hyperplasia, Atypical 267KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/alimentary/forestomach/hyperpat/stomach-forestomach-epithelium-hyperplasia-atypical-pdf_508.pdf
Forestomach, Epithelium - Hyperplasia, Atypical Figure Legend: Figure 1 Stomach, Forestomach, Epithelium - Hyperplasia, Atypical in a female F344/N rat from a subchronic study. ...
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TR-210: 1,2-Dibromoethane (CASRN 106-93-4) in F344 Rats and B6C3F1Mice... 6.5MB
https://ntp.niehs.nih.gov/go/tr210
0 /""£ CARCINOGENESIS BIOASSAY OF 1,2-DIBROMOETHANE (CAS NO. 106-93-4) IN F344 RATS AND B6C31 MICE (INHALATION STUDY) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health ...
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15th RoC: Appendix F 174KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf
71.1.1711999472.152.1804289383% X-Anytotx-Content-Type: application/pdf X-Anytotx-Identified-By: command-line Content-Type: text/plain; charset=UTF-8 Content-Transfer-Encoding: ...
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RoC Background Document: 2,2-bis(Bromomethyl)-1,3- propanediol... 4.6MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/bbmp_no_appendices_508.pdf
FINAL Report on Carcinogens Background Document for 2,2-bis(Bromomethyl)-1,3- propanediol (Technical Grade) Meeting of the NTP Board of Scientific Counselors Report on Carcinogens ...
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TOX-57: Benzyltrimethylammonium Chloride (CASRN 56-93-9) 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox057.pdf
National Toxicology Program Toxicity Report Series Number 57 NTP Technical Report on the Toxicity Studies of Benzyltrimethylammonium Chloride (CAS No. 56-93-9) Administered by ...
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Stomach, Forestomach, Epithelium - Hyperplasia, [Focal, Diffuse... 302KB
https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/stomach-forestomach/Epithelium-Hyperplasia[FocalDiffuse]
Hyperplasia is defined as an increase in the number of cells in one or more epithelial strata (basal, spinous, or granulosum). Hyperkeratosis (increased thickness of the stratum ...
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Presentation: Fundamentals of QSAR Modeling: Basic Concepts and... 7.7MB
https://ntp.niehs.nih.gov/iccvam/meetings/commprac-2016/tropsha-508.pdf
Fundamentals of QSAR modeling: basic concepts and applications Alexander Tropsha University of North Carolina, Chapel Hill, USA Key points . Basic concepts and best practices of ...