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TR-546: Sodium Dichromate Dihydrate (CASRN 7789-12-0) in F344... 8.9MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr546.pdf
... National Toxicology Program (NTP) (1997). Final Report on the Reproductive Toxicity of Potassium Dichromate (CAS No. 7778-50-9) Administered in Diet to BALB/c Mice. NTIS No. ...
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TOX-72: Sodium Dichromate Dihydrate (CASRN 7789-12-0) 14.9MB
https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox072.pdf
... December 13, 1996. National Toxicology Program (NTP) (1997). Final Report on the Reproductive Toxicity of Potassium Dichromate (CAS No. 7778-50-9) Administered in Diet to BALB/c ...
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Abstract for TOX-72 66KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox072
72abs Abstract for TOX-72 Toxicity Studies of Sodium Dichromate Dihydrate Administered in Drinking Water to Male and Female F344/N Rats and B6C3F1 Mice and Male BALB/c and ...
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Abstract for TR-546 73KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr546
6abs Abstract for TR-546 Toxicology and Carcinogenesis Studies of Sodium Dichromate Dihydrate in F344/N Rats and B6C3F1 Mice (Drinking Water Studies) CASRN: 7789-12-0 Chemical ...
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Abstract for RACB95001 59KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb95001
Reproductive Toxicity of Potassium Dichromate (Hexavalent) Administered in Diet to SD Rats CASRN: 7778-50-9 Chemical Formula: Cr2H2O7.2K Molecular Weight: 294.18 Report Date: Dec. ...
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Abstract for RACB95002 60KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb95002
Reproductive Toxicity (Testicular) of Potassium Dichromate (Hexavalent) Administered in Diet to BALB/c Mice CASRN: 7778-50-9 Chemical Formula: Cr2H2O7.2K Molecular Weight: 294.18 ...
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Abstract for RACB94014 61KB
https://ntp.niehs.nih.gov/publications/abstracts/repro/racb94014
Reproductive Toxicity of Potassium Dichromate (Hexavalent) (CAS 7778-50-9) Administered in Diet to BALB/c Mice CASRN: 7778-50-9 Chemical Formula: Cr2H2O72K Molecular Weight: 294.18 ...
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Target Organs and Levels of Evidence for TR-546 62KB
https://ntp.niehs.nih.gov/data/tr/500s/tr546levels
6 Target Organs and Levels of Evidence for TR-546 Toxicology and Carcinogenesis Studies of Sodium Dichromate Dihydrate (CASRN 7789-12-0) in F344/N Rats and B6C3F1 Mice (Drinking ...
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Hexavalent Chromium 70KB
https://ntp.niehs.nih.gov/whatwestudy/topics/hexchrom
hexchrom Hexavalent Chromium Brown water pouring from large metal pipes into a water reservoir with the text Cr6 plus on the bottom left of the photo Research Overview Status: ...
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Minutes: BSC TRRS; May 17, 2007 271KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2007/may/trrs17may2007mins_508.pdf
NATIONAL TOXICOLOGY PROGRAM BOARD OF SCIENTIFIC COUNSELORS Technical Reports Review Subcommittee May 16-17, 2007 NIEHS, Research Triangle Park, NC Summary Minutes Contents Page ...
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RoC Profile: Chromium Hexavalent Compounds; 15th RoC 2021 174KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/chromiumhexavalentcompounds.pdf
Chromium Hexavalent Compounds CAS No. 18540-29-9 Known to be human carcinogens First listed in the First Annual Report on Carcinogens (1980) Carcinogenicity Chromium hexavalent ...
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Historical Controls: Pathology Tables by Oral/Water for B6C3F1... 100KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/mice_dwater_path_hist09.pdf
2011406 09/04/02 729 50 (1) 33(700) 55.6 Sodium dichromate dihydrate (VI) Southern Research Institute 059601906 10/10/01 729 50 (1) 38(696) 54.1 Water disinfection byproducts ...
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Historical Controls: Pathology Tables by Oral/Water for Fischer... 100KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/rats_dwater_path_hist09.pdf
2011407 10/02/02 730 50 (3) 28(696) 532.4 Sodium dichromate dihydrate (VI) Southern Research Institute 059601905 09/26/01 729 50 (3) 31(686) 526.0 Water disinfection byproducts ...
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Historical Controls: Pathology Tables by Oral/Water for B6C3F1... 139KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/oralwatermice2010mar.pdf
2/2010 Species: MICE Route: ORAL Strain: B6C3F1 Vehicle: WATER Length of Study: CHRONIC Study Summary Laboratory Name Study Number Study Start Date Length of Study in Days Number ...
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Historical Controls: Pathology Tables by Oral/Water for Fischer... 140KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/oralwaterrats2010mar.pdf
0/2010 Species: RATS Route: ORAL Strain: F 344/N Vehicle: WATER Length of Study: CHRONIC Study Summary Laboratory Name Study Number Study Start Date Length of Study in Days Number ...
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Historical Controls: Pathology Tables by Oral/Water for B6C3F1... 140KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/miceoralwater.pdf
248 Contract/Lab: All Laboratories Tumor Incidence for Selected Control Animal Groups Report Date: 05/04/2011 Species: MICE Route: ORAL Strain: B6C3F1 Vehicle: WATER Length of ...
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Historical Controls: Pathology Tables by Oral/Water for Fischer... 136KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/ratsoralwater.pdf
30 Contract/Lab: All Laboratories Tumor Incidence for Selected Control Animal Groups Report Date: 05/18/2011 Species: RATS Route: ORAL Strain: F 344/N Vehicle: WATER Length of ...
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Agenda: BSC TRRS; May 16-17, 2007 102KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2007/may/trrs16may2007agenda_508.pdf
NATIONAL TOXICOLOGY PROGRAM BOARD OF SCIENTIFIC COUNSELORS Technical Reports Review Subcommittee Meeting Tentative Agenda May 16-17, 2007 8:30 a.m. - 5:00 p.m. National Institute ...
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Historical Controls: Chemicals by Species/Route/Vehicle for Fischer... 206KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009_byroute.pdf
Species Route Vehicle Chemical Mice Gavage Corn Oil Isoeugenol Mice Gavage Corn Oil 3,3',4,4'-Tetrachloroazobenzene Mice Gavage Corn Oil Pulegone Mice Gavage Corn Oil Kava Kava ...
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Stomach - Metaplasia, Squamous - Nonneoplastic Lesion Atlas 288KB
https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/stomach-glandular-stomach/MetaplasiaSquamous
Squamous metaplasia of the glandular stomach is characterized by a reversible change in which cuboidal or columnar mucosal epithelial cells are replaced by squamous epithelial ...
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Public Health Impact 1.5MB
https://ntp.niehs.nih.gov/media/impact
... Potassium Dichromate (Hexavalent) (CASRN 7778-50-9) Administered in Diet to BALB/c Mice. ... Dichromate (Hexavalent) (CASRN 7778-50-9) Administered in Diet to BALB/c Mice. ...
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Historical Controls: Chemicals by Sex/Species/Route/Vehicle for... 14KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/histcont_2010_studies.pdf
Species: MICE Studies on Historical Control Reports Report Date: 03/22/2010 Strain: B6C3F1 List of Studies - Mice Species Strain Sex Route Vehicle Chemical Mice B6C3F1 Male and ...
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Historical Controls: Chemicals by Sex/Species/Route/Vehicle for... 83KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont_2011_studies.pdf
Version: May2011 Toxicology Data Management System Page: 1 Species: MICE Studies on Historical Control Reports Report Date: 05/18/2011 Strain: B6C3F1 List of Studies - Mice Species ...
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Reproductive Abstracts 202KB
https://ntp.niehs.nih.gov/publications/abstracts/repro
... Dichromate (Hexavalent) (CASRN: 7778-50-9) Administered in Diet to BALB/c Mice ... Dichromate (Hexavalent) (CASRN: 7778-50-9) Administered in Diet to SD Rats 1996 ...
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Study Abstracts 375KB
https://ntp.niehs.nih.gov/publications/abstracts
... Dichromate (Hexavalent) (CASRN: 7778-50-9) Administered in Diet to BALB/c Mice ... Dichromate (Hexavalent) (CASRN: 7778-50-9) Administered in Diet to SD Rats 1996 ...
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ICCVAM Test Method Evaluation Report on the LLNA: DA 30.4MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-da/tmer.pdf
... 5, 8 PDC; Dipotassium bichromate 7778-50-9 294.18 -3.59 NA Solid Inorganic ... LLNA Ref. 5.0 4.5 4.0 3.5 3.0 2.5 2.0 1.8 1.5 1.3 1.0 Potassium dichromate 7778-50-9 1.0 ...
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ICCVAM Test Method Evaluation Report on the Reduced LLNA 21.6MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ld/tmer.pdf
... - Gerberick Potassium dichromate PDC 7778-50-9 294.18 0.62 Solid Inorganic Chemical, ... et al. (2005) Potassium dichromate 7778-50-
9 DMSO + + 0.08 0.025 1.60 0.05 1.40 0.1 ...
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Stomach, Glandular Stomach - Metaplasia, Squamous 293KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/alimentary/glandular_stomach/metapsq/glandular-stomach-metaplasia-squamous_508.pdf
Squamous Figure Legend: Figure 1 Stomach, Glandular stomach - Metaplasia, Squamous in a male B6C3F1 mouse from a chronic study. The normal epithelium of the gastric glands is ...
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Stomach, Glandular Stomach, Epithelium - Vacuolation, Cytoplasmic... 288KB
https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/stomach-glandular-stomach/Epithelium-VacuolationCytoplasmic
Cytoplasmic vacuolation is generally considered to be an early form of degeneration. Cytoplasmic vacuolization (Figure 1 image opens in a pop-up window and Figure 2 image opens in ...
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Tongue - Ulcer - Nonneoplastic Lesion Atlas 288KB
https://ntp.niehs.nih.gov/atlas/nnl/alimentary-system/tongue/Ulcer
Ulcers and erosions can occur anywhere in the gastrointestinal tract, including the tongue. An erosion involves the loss of superficial epithelium of the mucosa, whereas an ulcer ...
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Historical Controls: All Routes and Vehicles for Mice; Studies... 211KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/m_hcrpt_allrte20071000_508.pdf
October 2007 REPORT DESCRIPTION This report shows the tumor rates of control group animals from selected studies. The studies used are shown on the Study Summary page. The report ...
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Historical Controls: All Routes and Vehicles for Rats; Studies... 225KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/r_hcrpt_allrte20071000_508.pdf
October 2007 REPORT DESCRIPTION This report shows the tumor rates of control group animals from selected studies. The studies used are shown on the Study Summary page. The report ...
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Stomach, Glandular Stomach, Epithelium - Vacuolation, Cytoplasmic 293KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/alimentary/glandular_stomach/vacuol/glandular-stomach-vacuolation-cytoplasmic_508.pdf
Stomach, Epithelium - Vacuolation, Cytoplasmic Figure Legend: Figure 1 Stomach, Glandular stomach, Epithelium - Vacuolation, Cytoplasmic in a male F344/N rat from a subchronic ...
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Tongue - Ulcer 275KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/alimentary/tongue/ulcer/tongue-ulcer-pdf_508.pdf
Tongue - Ulcer Figure Legend: Figure 1 Tongue - Ulcer in a female F344/N rat from a chronic study. A portion of the keratinized squamous epithelium of the tongue has been lost, ...
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Historical Controls: All Route and Vehicles for Rats; Studies... 162KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2008/r_hcrtp_allrte_20081100.pdf
NTP Historical Controls Report All Routes And Vehicles RATS November 2008 REPORT DESCRIPTION This report shows the tumor rates of control group animals from selected studies. The ...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 176KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009-05-14-hist-miceallroutes.pdf
MICE May 2009 REPORT DESCRIPTION This report shows the tumor rates of control group animals from selected studies. The studies used are shown on the Study Summary page. The report ...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 174KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009-05-14-hist-ratsallroutes.pdf
All Routes And Vehicles RATS May 2009 REPORT DESCRIPTION This report shows the tumor rates of control group animals from selected studies. The studies used are shown on the Study ...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 307KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/2010-03-22-hist-miceallroutes.pdf
All Routes and Vehicles MICE March 2010 REPORT DESCRIPTION This report shows the tumor rates of control group animals from selected studies. The studies used are shown on the Study ...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 309KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/2010-03-22-hist-ratsallroutes.pdf
All Routes and Vehicles RATS March 2010 REPORT DESCRIPTION This report shows the tumor rates of control group animals from selected studies. The studies used are shown on the Study ...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 308KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_mice_allroutes.pdf
MICE May 2011 REPORT DESCRIPTION This report shows the tumor rates of control group animals from selected studies. The studies used are shown on the Study Summary page. The report ...
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Historical Controls: Pathology Tables All Routes/Vehicles for... 309KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_rats_allroutes.pdf
All Routes and Vehicles F 344/N RATS May 2011 REPORT DESCRIPTION This report shows the tumor rates of control group animals from selected studies. The studies used are shown on the ...
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Lymph node - Hyperplasia, Lymphocyte - Nonneoplastic Lesion Atlas 293KB
https://ntp.niehs.nih.gov/atlas/nnl/immune-system/lymph-node/HyperplasiaLymphocyte
In rodents, lymphocyte hyperplasia may involve various anatomical compartments of the lymph nodes, including the B-cell-rich follicles (follicular), the T-cell-rich paracortex ...
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Lymph Node - Hyperplasia, Lymphocyte 435KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/immune/lymph_node/hyperly/lymph-node-hyperplasia-lymphocyte-pdf_508.pdf
Lymphocyte Figure Legend: Figure 1 Lymph node - Hyperplasia, Lymphocyte in a male F344/N rat from a subchronic study. The lymph node paracortex is expanded by increased numbers of ...
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Validation of In Vitro Cytotoxicity Test Methods: Test Chemicals 188KB
https://ntp.niehs.nih.gov/iccvam/methods/acutetox/invitrocyto/ivcytodocs/valstdchm.pdf
In Vitro Cytotoxicity Validation Study Test Chemicals Test Chemical CAS # Molecular Weight Supplier Product Code Purity (%) Acetaminophen 103-90-2 151.20 SIGMA A7085 99 ...
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TR-556: Chromium Picolinate Monohydrate (CASRN 27882-76-4) in... 6.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr556.pdf
CHROMIUM PICOLINATE MONOHYDRATE (CAS NO. 27882-76-4) IN F344/N RATS AND B6C3F1 MICE (FEED STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 June ...
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ICCVAM Test Method Evaluation Report on the Applicability Domain... 16.1MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ad/tmer-revmay2012.pdf
... Potassium dichromate 7778-50-9 DMSO 0.025, 0.05, 0.1, 0.25, 0.5 1.6, 1.4, 3.8, 5.3, 16.1 ... Kligman (1966c) Potassium dichromate 7778-50-9 DMSO 0.025, 0.05, 0.1, 0.25, 0.5 1.4, ...
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Presentation: The Murine Local Lymph Node Assay: DA 1010KB
https://ntp.niehs.nih.gov/iccvam/meetings/implement-2011/acd-present/7-salicru.pdf
Murine Local Lymph Node Assay: Daicel Chemical Industries, Ltd., Based on ATP Content (LLNA: DA) ICCVAM Workshop Series on Best Practices for Regulatory Safety Testing: Assessing ...
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Short-Term Toxicity Reports 224KB
https://ntp.niehs.nih.gov/publications/reports/tox
TOX-106 PDF (2.68 MB) Toxicity Studies of Sodium Metavanadate (CASRN 13718-26-8) and Vanadyl Sulfate (CASRN 27774-13-6) Administered in Drinking Water to Sprague Dawley ...
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TR-132: 2,5-Dithiobiurea (CASRN 142-46-1) 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr132.pdf
9 National Cancer Institute CARCINOGENESIS Technical Report Series No. 132 BIOASSAY OF 2,5-DITHIOBIUREA FOR POSSIBLE CARCINOGENICITY CAS No. 142-46-1 NCI-CG-TR-132 U.S. DEPARTMENT ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
9433 Conclusion by Sex/Species Report No. Peer Review Date/Target Organs Substance Name CASRN Male Rats Female Rats Male Mice Female Mice TR-603 01/01/23 Black Cohosh 84776-26-1 NE ...