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Search suggestions for "78-79-5".

  1. Report on Carcinogens Isoprene https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/isoprene.pdf
  2. CEBS Data Related to Isoprene (78-79-5) https://cebs.niehs.nih.gov/cebs/test_article/78-79-5


93 results found for "78-79-5".

  1. TR-486: Isoprene (CASRN 78-79-5) in F344/N Rats (Inhalation Studies... 11.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr486.pdf

    ISOPRENE (CAS NO. 78-79-5) IN F344/N RATS (INHALATION STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 July 1999 NTP TR 486 NIH Publication No. ...

  2. TOX-31: Isoprene (CASRN 78-79-5) 7.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox031.pdf

    1 NTP Technical Report on Toxicity Studies of Isoprene (CAS No. 78-79-5) Administered by Inhalation to F344/N Rats and B6C3F Mice 1 Ronald L. Melnick, Ph.D., Study Scientist ...

  3. RoC Background Document: Isoprene; Dec. 2-3, 1998 2.2MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/isoprene_oneapp_508.pdf

    ISOPRENE FINAL MARCH 1999 Prepared for the December 2-3, 1998, Meeting of the Report on ... NOl-ES-25346 I, NTP Report on Carcinogens 1998 Background Document for Isoprene TABLE OF ...

  4. RoC Profile: Isoprene; 15th RoC 2021 158KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/isoprene.pdf

    Isoprene CAS No. 78-79-5 Reasonably anticipated to be a human carcinogen First listed in the Ninth Report on Carcinogens (2000) H C C H 2 C CH 2 CH 3 Carcinogenicity Isoprene is ...

  5. Abstract for TOX-31 66KB

    https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox031

    31abs Abstract for TOX-31 Toxicity Studies of Isoprene Administered by Inhalation to F344/N Rats and B6C3F1 Mice CASRN: 78-79-5 Chemical Formula: C5H8 Molecular Weight: 68.1 ...

  6. Abstract for TR-486 70KB

    https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr486

    Abstract for TR-486 Toxicology and Carcinogenesis Studies of Isoprene in F344/N Rats (Inhalation Studies) CASRN: 78-79-5 Chemical Formula: C5H8 Molecular Weight: 68.1 Synonyms/...

  7. Minutes: BSC TRRS; Dec. 9, 1997 1.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1997/dec/trrs9dec1997mins_508.pdf

    Purified Isobutene Isoprene Furfuryl Alcohol Pyridine 1-Chloro-2-propanol, Technical 111-42-2 68603-42-9 120-40-1 93-83-4 87-86-5 115-11-7 78-79-5 98-00-0 110-86-1 127-00-4 ...

  8. Abstract for TER88045 and TER88142 62KB

    https://ntp.niehs.nih.gov/publications/abstracts/dev/ter88045

    Abstract for TER88045 and TER88142 Inhalation Developmental Toxicology Studies: Teratology Study of Isoprene in Mice and Rats CASRN: 78-79-5 Chemical Formula: C5H8 Molecular ...

  9. Target Organs and Levels of Evidence for TR-486 58KB

    https://ntp.niehs.nih.gov/data/tr/400s/tr486levels

    Target Organs and Levels of Evidence for TR-486 Toxicology and Carcinogenesis Studies of Isoprene (CASRN 78-79-5) in F344/N Rats (Inhalation Studies) Chemical (Study Title) CASRN ...

  10. RoC Background Document: Chloroprene; Oct. 30-31, 1997 5.9MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/chloroprene1_508be.pdf

    ......... 18 6.3.2 Isoprene ......analogue of 1 ,3-butadiene, while isoprene is the 2-methyl analog of 1 ,3-butadiene. ...

  11. Abstract for TR-151 62KB

    https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr151

    acid is used commercially as a rubber accelerator in applications involving natural rubber, and styrene-butadiene, isobutylene-isoprene, isoprene, and butadiene rubber. ...

  12. Abstract for TR-166 62KB

    https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr166

    ethyl tuads where it is used in compounding natural rubber and the synthetic elastomers isobutylene-isoprene, butadiene, styrene-butadiene, isoprene, and nitrile-butadiene rubber. ...

  13. Minutes: BSC TRRS; Nov. 16, 1993 800KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1993/nov/trrs16nov1993mins_508.pdf

    ... Dimethyl Phthalate 131-1 1-3 Dermal Short-Term Toxicity Study Isoprene 78-79-5 Inhalation SUMMARY MINUTES NTP TECHNICAL REPORTS REVIEW SUBCOMMITTEE MEETING November 16-17, 1993 ...

  14. Public Health Impact 1.5MB

    https://ntp.niehs.nih.gov/media/impact

    Year Agency Title CASRN 2024 OEHHA Inhalation Unit Risk Factor (IUR) for Isoprene The ... unit risk factor (IUR) for isoprene, as part of the Air Toxics Hot Spots program. ...

  15. TR-487: Isobutene (CASRN 115-11-7) in F344/N Rats and B6C3F1Mice... 11.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr487.pdf

    ... the biotransformation macokinetics of isoprene, which is structurally related of ... Metabolism of isoprene was linear in rats incubation, and lung epoxide concentrations at 1 ...

  16. Appendix G; 15th RoC 2021 73KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf

    ... see Dimethyl Sulfate 78-00-2 (tetraethyl lead) see Lead and Lead Compounds 78-79-5 see Isoprene 79-01-6 see Trichloroethylene 79-06-1 see Acrylamide 79-43-6 (dichloroacetic ...

  17. Studies on Historical Control Reports for NIH-07 Feed 312KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/nih-07_1999/histcont_1999_by_list_of_studies_508.pdf

    Rats Fischer344 Inhalation Air Isobutyraldehyde Rats Fischer344 Inhalation Air Isoprene Rats Fischer344 Inhalation Air Molybdenum trioxide Rats Fischer344 Inhalation Air ...

  18. Minutes: BSC; April 6, 1994 2.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1994/april/19940406bscmins_508.pdf

    ... There previously had been an NTP two-year gavage study . Studies with isoprene involved 26-week inhalation exposures followed by a 26-week recovery period, and as expected, based ...

  19. TR-467: Chloroprene (CASRN 126-99-8) in F344/N Rats and B6C3F1Mice... 14.5MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr467.pdf

    ... responses between rats and and isoprene (2-methyl-1,3-butadiene) to see if ... potential Epidemiologic studies have consistently associated of chloroprene and isoprene. ...

  20. TR-140: Pivalolactone (CASRN 1955-45-9) 3.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr140.pdf

    ... with acrylics (Shor and Van Dyk, 1975), isoprene and butadiene (Foss et al., 1976; Foss, ... "B" 34:187-220, 1972. Foss, R.P., "Copolymers of Pivalolactone and Isoprene or Butadiene." ...

  21. TR-151: Lead Dimethyldithiocarbamate (CASRN 19010-66-3) 2.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr151.pdf

    ... used commercially as a rubber accelerator in applications involving natural rubber, and styrene-butadiene, isobutylene-isoprene, isoprene, and butadiene rubber (Del Gatto, 1968). ...

  22. TR-166: Tetraethylthiuram Disulfide (CASRN 97-77-8) 3.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr166.pdf

    ... it is used in compounding natural rubber and the synthetic elastomers isobutylene-isoprene, butadiene, styrene-butadiene, isoprene, and nitrile-butadiene rubber (Del Gatto, 1968). ...

  23. TR-557: beta-Myrcene (CASRN 123-35-3) in F344/N Rats and B6C3F1... 16.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr557.pdf

    ... to isoprene, also known to form monoexpoxides and a diepoxide (Watson et al., 2001). Mutagenic activity was observed for the diepoxide, but not the monoepox- ides, of isoprene in ...

  24. Listed Substances; 15th RoC 2021 76KB

    https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf

    ... (see Polycyclic Aromatic Hydrocarbons: 15 Listings) Iron Dextran Complex Isoprene Kepone Lead and Lead Compounds Lindane, Hexachlorocyclohexane (Technical Grade), and ...

  25. TR-510: Urethane + Ethanol (CASRNs. 51-79-6 & 64-17-5) in F344... 17.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr510.pdf

    ... He noted the similarity in carcinogenic effects of urethane, butadiene, and isoprene. ... Ethanol, and Urethane/Ethanol, NTP TR 510 isoprene (reviewed by Melnick and Sills, 2001). ...

  26. Completed RoC Evaluations 119KB

    https://ntp.niehs.nih.gov/whatwestudy/assessments/cancer/completed/roc

    ... Human T-cell Lymphotrophic Virus Type 1 (HTLV-1) Known to be a human carcinogen RoC Review of Human T-cell Lymphotrophic Virus Type 1 (HTLV-1) Isoprene Reasonably anticipated to be ...

  27. RoC Background Document: Tobacco Smoking; Dec. 2-3, 1998 3.5MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/environmentalts_noapps_508.pdf

    ... mg 0.2-0.5 mg Norman et al. (1983) Volatile hydrocarbons Ethene Propene 1,3-Butadiene Isoprene Formaldehyde 1.2 mg 1.3 mg 0.4 mg 3.1 mg 1500 µg 0.24 mg 0.18 mg 0.03 mg 0.70 mg 30 ...

  28. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... SE Some Evidence NE No Evidence NE No Evidence NE No Evidence TR-486 12/10/97 Isoprene 78-79-5 P Clear Evidence SE Some Evidence NT Chemical Not Tested in Species/Sex NT ...

  29. RoC Profile: Chloroprene; 15th RoC 2021 140KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/chloroprene.pdf

    ... Last accessed: 5/09. Tice RR, Boucher R, Luke CA, Paquette DE, Melnick RL, Shelby MD. 1988. Chloroprene and isoprene: Cytogenetic studies in mice. Mutagenesis 3(2): 141-146. ...

  30. Short-Term Toxicity Reports 224KB

    https://ntp.niehs.nih.gov/publications/reports/tox

    ... B6C3F1 Mice 1993 Short-Term Toxicity TOX-31 PDF (7.18 MB) Toxicity Studies of Isoprene (CASRN 78-79-5) Administered by Inhalation to F344/N Rats and B6C3F1 Mice 1995 Short-Term ...

  31. TOX-3: Acetone (CASRN 67-64-1) 2.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox003.pdf

    ... bisphenol A, methyl isobutyl ketone, hexylene glycol (2-methyl-2,4- pentanediol), isoprene, and isophorone (Rowe and Wolf, 1963; Nelson and Webb, 1978, 1985; Merck, 1983). ...

  32. TOX-81: α-Pinene (CASRN 80-56-8) Administered by Inhalation... 2.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox081_508.pdf

    ... class of chemicals, which are based on isoprene units and represent the largest group of ... known as monoterpenes, which contain two isoprene units and include other members that are ...

  33. RoC Background Document: 1,3-Butadiene; Oct. 30-31, 1997 9.0MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/butadiene_508.pdf

    ... 6.3 Structure-Activity Relationships Isoprene is a 2-methyl analog of 1,3-butadiene ... evidence for the carcinogenicity of isoprene in experimental animals and that ...

  34. Minutes: BSC TRRS; Sept. 5, 2002 128KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2002/sept/trrs5sept2002mins_508.pdf

    ... OF SCIENTIFIC COUNSELORS Summary Minutes - September 5-6, 2002 He noted the similarity in carcinogenic effects of urethane, butadiene, and isoprene. Regarding the conclusions, Dr. ...

  35. Minutes: BSC; Dec. 13, 1996 288KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1996/december/19961213_bsc_508.pdf

    ... He illustrated how SAR and dose-response information on 1,3-butadiene led to selection of the analogs, isoprene and chloroprene for study. Dr. Melnick also described some of the ...

  36. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... Report TR-486 PDF (11.89 MB) Toxicology and Carcinogenesis Studies of Isoprene (CASRN 78-79-5) in F344/N Rats (Inhalation Studies) 1999 Technical Report TR-485 PDF (12.47 ...

  37. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... Report TR-486 PDF (11.89 MB) Toxicology and Carcinogenesis Studies of Isoprene (CASRN 78-79-5) in F344/N Rats (Inhalation Studies) 1999 Technical Report TR-485 PDF (12.47 ...

  38. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... TR-486 PDF (11.89 MB) Toxicology and Carcinogenesis Studies of Isoprene (CASRN 78-79-5) in F344/N Rats (Inhalation Studies) 1999 Long-Term Carcinogenicity TR-485 PDF ...

  39. Appendices A-G; 15th RoC 2021 448KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf

    ... 2-methyl-1,3-butadiene see Isoprene methyl-CCNU see Nitrosourea ... lead) see Lead and Lead Compounds 78-79-5 see Isoprene 79-01-6 see ...

  40. 15th RoC: Appendix F 174KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf

    ... 4-methyl-1,3-benzenediamine see 2,4-Diaminotoluene 2-methyl-1,3-butadiene see Isoprene methyl-CCNU see Nitrosourea Chemotherapeutic Agents, 1-(2-Chloroethyl)-3-(4-methylcyc...

  41. TR-347: d-Limonene (CASRN 5989-27-5) in F344/N Rats and B6C3F1Mice... 9.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr347.pdf

    ... (CEH, 1976), and in 1984,254,000 kg was consumed in the United States. d-limonene is the most widely distributed op- tically active terpene and is closely related to isoprene. ...

  42. TR-505: Citral (Microencapsulated) (CASRN 5392-40-5) in F344... 10.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr505.pdf

    ... It is syn- thesized from isoprene, by dehydrogenation of a gera- niol-nerol mixture obtained from $-pinene, or by oxidation of geraniol, nerol, or linalool by chromic acid (HSDB, ...

  43. Minutes: BSC; April 13, 2011 257KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2011/april/minutesbsc20110413.pdf

    ... Dr. Peddada showed an example of a test of isoprene in female rats, assessing mammary gland fibroadenomas. The Poly-3 p-value was not significant, but applying the Max-Iso-Poly-3 ...

  44. Minutes: BSC; July 14, 1987 1.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1987/december/19871214bsc_minutes_508be.pdf

    ... Among o t h e r chemicals s t u d i e d were 2,3-dichloropropane, 1-chloro-2-propanol, methyl bromide, azodicarbonamide, isoprene, s t y r e n e , and t h r e e g l y c o l e t h e ...

  45. TR-490: Glutaraldehyde (CASRN 111-30-8) in F344/N Rats and B6C3F1Mice... 10.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr490.pdf

    ... of Health, Research Triangle Park, NC. National Toxicology Program (1999b). Toxicology and Carcinogenesis Studies of Isoprene (CAS No. 78-79-5) in F344/N Rats (Inhalation Studies). ...

  46. Minutes: BSC; May 20, 1999 365KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1999/may/19990520bscmins_508.pdf

    ... Ethylene Oxide was recommended for upgrading to a known to be human carcinogen; (7) Isoprene was recommended for listing as reasonably anticipated to be a human carcinogen; (8) ...

  47. RoC Background Document: Tetrafluoroethylene; March 1999 4.5MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/tetrafluoroethylene1.pdf

    ... nylon 6/6; dimethylterephthalate, terephthalic acid and polyethylene terephthalate; isoprene and polyisoprene; methacrylic acid; vinylidene fluoride and polyvinylidene fluoride. ...

  48. Minutes: BSC; Feb. 5, 1998 713KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1998/february/19980205bscmins_508.pdf

    ... alcoholic beverages, ethylene oxide, isoprene, boot and shoe manufacturing (worker ... furfuryl alcohol, isobutene, isoprene, pentachlorophenol, and pyridine. Dr. ...

  49. Cumene: Preliminary Literature Search Strategy and List of References 698KB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/litsearchstrategy/cumene-litsearch&references5oct2012_508.pdf

    ... (2-chloro-1,3-butadiene) for 2 years, and comparisons with the structurally related chemicals isoprene and 1,3-butadiene. Carcinogenesis 20(4): 657-662. (Support not reported. ...

  50. Minutes: BSC; May 24, 2000 495KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2000/may/2000052400bscsummmins_508.pdf

    ... New entries to the reasonably anticipated category include chloroprene, diesel exhaust particulates, isoprene, phenolphthalein, tetrafluoroethylene, and trichloroethylene. Several ...

 
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