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5 results found for "79902-63-9".
  1. Presentation: Setting the Stage: Purpose, Definitions, Scope... 2.1MB

    https://ntp.niehs.nih.gov/iccvam/meetings/ivive-wksp-2016/webinar-slides/1-wetmore-07oct2015-fd-508.pdf

    ... APR_MitoMembPot 1 4.9835 83-79-4 Rotenone 0.3131 APR_MitoticArrest 1 3.1941 79902-63-9 Simvastatin 0.6379 APR_CellCycleArrest 1 1.5677 79902-63-9 Simvastatin 0.6379 APR_MitoMass ...

  2. Modernizing Drug Discovery Using (ICCVAM Communities of Practice... 6.0MB

    https://ntp.niehs.nih.gov/iccvam/meetings/commprac-2023/20230130-iccvam-cop-ewart-508.pdf

    ... Chlorpheniramine Reactive Oxygen Species production No Yes Labetalol Metabolism leading to toxic intermediate No Yes Simvastatin Metabolism leading to toxic intermediate No Yes ...

  3. Presentation: What is an AOP (and What ISN'T It?) 741KB

    https://ntp.niehs.nih.gov/iccvam/meetings/aop-wksp-2014/presentations/mendrick-508.pdf

    ... Agents that lower LDL and/or raise HDL assumed to reduce risk of cardiovascular disease 17 Ezetimide . Lowers LDL and approved by the FDA . ENHANCE trial: Ezetimide + simvastatin ...

  4. TR-603: Black Cohosh Root Extract (CASRN 84776-26-1) Administered... 3.1MB

    https://ntp.niehs.nih.gov/sites/default/files/2023-12/tr603_508.pdf

    ... Esposti DD, Wu HA, Balick M, Ma H, Redenti S, Roter A. A transcriptomic analysis of black cohosh: Actein alters cholesterol biosynthesis pathways and synergizes with simvastatin. ...

  5. TR-248: 4,4'-Methylenedianiline Dihydrochloride (CASRN 13552... 9.5MB

    https://ntp.niehs.nih.gov/go/tr248

    ... 153 290 06113/79 06114/79 150 300 07125/79 07126/79 150 300 10117/79 10118/79 148 290 12105/79 12106/79 149 290 12126/79 12127/79 148 287 01130180 01131/80 153 (148, c) 306 ...

 
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