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TR-314: Methyl Methacrylate (CASRN 80-62-6) in F344/N Rats and... 11.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr314.pdf
STUDIES OF METHYL METHACRYLATE (CAS NO. 80-62-6) IN F344/N RATS AND B6C3Ft MICE ... TOXICOLOGY AND CARCINOGENESIS STUDIES OF METHYL METHACRYLATE (CAS NO. 80-62-6) IN F344/N ...
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Abstract for TR-314 64KB
https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr314
Toxicology and Carcinogenesis Studies of Methyl Methacrylate in F344/N Rats and B6C3F1 Mice (Inhalation Studies) CASRN: 80-62-6 Chemical Formula: C5H8O2 Molecular Weight: 100.11 ...
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Target Organs and Levels of Evidence for TR-314 58KB
https://ntp.niehs.nih.gov/data/tr/300s/tr314levels
80-62-6) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) Chemical (Study Title) CASRN Peer Review Date Route/Exposure Levels Study Laboratory Methyl methacrylate 80-62-6 12/...
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Minutes: BSC TRRS; Dec. 9, 1985 520KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1985/dec/85dec9trrsmins_508.pdf
n e Cas No. 7177-48-2 113-92-8 513-37-1 80-62-6 2058-46-0 79-01-6 Route Page Number Gavage 1 Gavage 3 Gavage 5 I n h a l a t i o n 6 Feed 7 Gavage 9 A m p i c i l l i n trihydrate. ...
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Background: Dimethylethanolamine (DMAE) [108-01-0] and Selected... 1.3MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/dmae_update_110002_508.pdf
Dimethylethanolamine (DMAE) [108-01-0] and Selected Salts and Esters DMAE Aceglutamate [3342-61-8] DMAE p-Acetamidobenzoate [281131-6] and [3635-74-3] DMAE Bitartrate [5988-51-2] ...
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ICCVAM Test Method Evaluation Report on the LLNA: DA 30.4MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-da/tmer.pdf
... 4 Structure Methyl methacrylate 7 MMA 80-62-6 100.12 NA NA Liquid Carboxylic acids ... 2008 + ICCVAM 1999 Methyl methacrylate 80-62-6 100 1.81 - + - - - - - - - - - + + + + ...
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RoC Background Document: Ethyl Acrylate; Dec. 2-3, 1998 834KB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/ethylacryl_noapps_508.pdf
Ethyl Acrylate December 2 - 3, 1998 Meeting of the NTP Board of Scientific Counselors Report on Carcinogens Subcommittee Prepared for the: U.S. Department of Health and Human ...
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Beyond 3-D Models: Building Confidence in Microphysiological... 2.5MB
https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2019/september/presentations/3-4-baran-508.pdf
YY..1..YY--1-Y.J...YY y ,.l.. y y ,.l.. y y y y --1- y y ..1.. y y --1- y .J... y y y ,.l.. y y .,1.. y y y y --1- y Y .,1.. Y Y .J... , .,1.. , Y Y .J... Y Y .J... Y Y Y ' --1- Y ...
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ICCVAM Test Method Evaluation Report: LLNA BrdU-ELISA 35.6MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-elisa/tmer.pdf
ICCVAM Test Method Evaluation Report on the Murine Local Lymph Node Assay: BrdU-ELISA A Nonradioactive Alternative Test Method to Assess the Allergic Contact Dermatitis Potential ...
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References Relevant to the 2007 LLNA Nomination to ICCVAM 70KB
https://ntp.niehs.nih.gov/iccvam/methods/immunotox/llnadocs/llna-2007-refs.pdf
References Relevant to the 2007 LLNA Nomination to ICCVAM Relevant Test Method Guidelines EPA. 2003. Health Effects Test Guidelines OPPTS 870.2600 Skin Sensitization. EPA 712-C- ...
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CERHR Monograph: Potential Human Reproductive and Developmental... 5.0MB
https://ntp.niehs.nih.gov/ntp/ohat/methanol/methanol_monograph.pdf
NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Methanol September 2003 NIH Publication No. 03-4478 Table of Contents Preface ...
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TR-346: Chloroethane (Ethyl Chloride) (CASRN 75-00-3) in F344... 8.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr346.pdf
6 TOXICOLOGY AND CARCINOGENESIS STUDIES OF CHLOROETHANE (ETHYL CHLORIDE) (CAS NO. 75-00-3) IN F344/N RATS AND B6C3F1 MICE (INHALATION STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN ...
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Recommended Performance Standards for the LLNA 2.2MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ps/llnaperfstds.pdf
... 12-48 NC +/+ +/+ 13 Methyl methacrylate 80-62-6 Liq AOO 90 1 45-100 NC +/+ +/+ 14 ... in September 2008. Methyl methacrylate 80-62-6 Liq AOO 90 1 X X Acrylate with concordant ...
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GMM-03: Genetically Modified Model Report on Trimethylolpropane... 7.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm03_508.pdf
... Toxicology and Carcinogenesis Studies of Methyl Methacrylate (CAS No. 80-62-6) in F344/N Rats and B6C3F 1 Mice (Inhalation Studies). Technical Report Series No. 314. NIH ...
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Presentation: The Murine Local Lymph Node Assay: BrdU-ELISA 889KB
https://ntp.niehs.nih.gov/iccvam/meetings/implement-2011/acd-present/6-strickland.pdf
Murine Local Lymph Node Assay: 5-Bromo-2-deoxyuridine Enzyme-linked Immunosorbent Assay (LLNA: BrdU-ELISA) ICCVAM Workshop Series on Best Practices for Regulatory Safety Testing: ...
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Presentation: The Murine Local Lymph Node Assay: DA 1010KB
https://ntp.niehs.nih.gov/iccvam/meetings/implement-2011/acd-present/7-salicru.pdf
Murine Local Lymph Node Assay: Daicel Chemical Industries, Ltd., Based on ATP Content (LLNA: DA) ICCVAM Workshop Series on Best Practices for Regulatory Safety Testing: Assessing ...
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15th RoC: Appendix B 103KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendix_b.pdf
5.1.1711999471.285.1804289383% X-Anytotx-Content-Type: application/pdf X-Anytotx-Identified-By: command-line Content-Type: text/plain; charset=UTF-8 Content-Transfer-Encoding: 8bit ...
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RoC Profile: Diazoaminobenzene; 15th RoC 2021 129KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/diazoaminobenzene.pdf
Diazoaminobenzene CAS No. 136-35-6 Reasonably anticipated to be a human carcinogen First listed in the Eleventh Report on Carcinogens (2004) Also known as 1,3-diphenyltriazene N N ...
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TR-576: Trimethylolpropane Triacrylate (Technical Grade) (CASRN... 6.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr576_508.pdf
TRIMETHYLOLPROPANE TRIACRYLATE (TECHNICAL GRADE) (CAS NO. 15625-89-5) IN F344/N RATS AND B6C3F1/N MICE (DERMAL STUDIES) National Toxicology Program P.O. Box 12233 Research Triangle ...
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TR-579: N,N-Dimethyl-P-Toluidine (CASRN 99-97-8) in F344/N Rats... 11.5MB
https://ntp.niehs.nih.gov/go/tr579
N,N-DIMETHYL-p-TOLUIDINE (CAS NO. 99-97-8) IN F344/N RATS AND B6C3F1/N MICE (GAVAGE STUDIES) National Toxicology Program P.O. Box 12233 Research Triangle Park, NC 27709 September ...
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Peer Review Report of the EpiSensA Skin Sensitization Assay ... 1.5MB
https://ntp.niehs.nih.gov/iccvam/meetings/sot23/sot2023-reinke-poster.pdf
Peer Review Report of the EpiSensA Skin Sensitization Assay E.N. Reinke 1 , E. Corsini 2 , A. Ono 3 , T. Fukuyama 4 , T. Ashikaga 5 , G.F. Gerberick 6 1 Inotiv, RTP, NC; 2 ...
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Appendices A-G; 15th RoC 2021 448KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf
Report on Carcinogens Report on Carcinogens, Fifteenth Edition National Toxicology Program, Department of Health and Human Services For Table of Contents, see home page: http://...
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TOX-3: Acetone (CASRN 67-64-1) 2.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox003.pdf
NTP REPORT ON THE TOXICITY STUDIES OF ACETONE IN F344/N RATS AND B6C3F 1 MICE (DRINKING WATER STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 ...
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Peer Review Panel Report: Updated Validation Status of the LLNA... 807KB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llnaprprept2009.pdf
... 149-30-4 Sol DMF 1 NA - 5 /+ - 5 /+ - 5 /+ X Methyl methacrylate 80-62-6 Liq AOO 1 NA - 6 /+ - 6 /+ - 6 /+ X Chlorobenzene 108-90-7 Liq AOO 1 NA - 6 /- - 6 /* ...
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RoC Background Document: 1,3-Butadiene; Oct. 30-31, 1997 9.0MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/butadiene_508.pdf
1,3-BUTADIENE FINAL MARCH 1999 Prepared for the October 30-31, 1997, Meeting of the Report on Carcinogens Subcommittee of the NTP Board of Scientific Counselors Prepared by ...
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Usefulness and Limitations of the LLNA for Potency Categorization... 25.3MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-pot/tmer.pdf
... Review Document O O methylmethacrylate 80-62-6 AOO 10 30 50 75 100 1.4 1.5 1.5 2.1 3.6 ... products Methyl methacrylate MMA 80-62-6 100.12 0.70 Liquid NA Carboxylic acids ...
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TR-267: Propylene Oxide (CASRN 75-56-9) in F344/N Rats and B6C3F1Mice... 7.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr267.pdf
7 /A~'"s., { ~r_ '<"+.,ltc.v.ua~ ...m TOXICOLOGY AND CARCINOGENESIS STUDIES OF PROPYLENE OXIDE (CAS NO. 75-56-9) IN F344/N RATS AND B6C3Ft MICE (INHALATION STUDIES) U.S. DEPARTMENT ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... Equivocal Evidence NE No Evidence NE No Evidence TR-314 12/09/85 Methyl Methacrylate 80-62-6 NE No Evidence NE No Evidence NE No Evidence NE No Evidence TR-313 03/04/87 Mirex ...
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Nomination Background: 1,3-Dichloro-2-propanol (CASRN: 96-23... 1.5MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/dichloropropanol_508.pdf
1,3-Dichloro-2-propanol [CAS No. 96-23-1] Review of Toxicological Literature January 2005 1,3-Dichloro-2-propanol [CAS No. 96-23-1] Review of Toxicological Literature Prepared for ...
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TR-326: Ethylene Oxide (CASRN 75-21-8) in B6C3F1Mice (Inhalation... 6.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr326.pdf
6 TOXICOLOGY AND CARCINOGENESIS STUDIES O F ETHYLENE OXIDE (CAS NO. 75-21-8) IN B6C3F1 MIiCE (INHALATION STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service ...
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RoC Background Document: Tetrafluoroethylene; March 1999 4.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/tetrafluoroethylene1.pdf
for TETRAFLUOROETHYLENE FINAL MARCH 1999 Prepared for the October 30-31, 1997, Meeting of the Report on Carcinogens Subcommittee of the NTP Board of Scientific Counselors Prepared ...
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Background Document: RoC: Styrene; 2010 4.3MB
https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/styrene_final_508.pdf
FINAL Report on Carcinogens Background Document for Styrene September 29, 2008 U.S. Department of Health and Human Services Public Health Servces National Toxicology Program ...
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TR-386: Tetranitromethane (CASRN 509-14-8) in F344/N Rats and... 12.9MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr386.pdf
86 TOXICOLOGY AND CARCINOGENESIS STUDIES OF TETRANITROMETHANE (CAS NO. 509-14-8) IN F344/N RATS AND B6C3F1 MICE (INHALATION STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES ...
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OECD Test Guideline 429: Skin Sensitisation: Local Lymph Node... 291KB
https://ntp.niehs.nih.gov/iccvam/suppdocs/feddocs/oecd/oecd-tg429-2010.pdf
... Imidazolidinyl urea 39236-46-9 Sol DMF 24 1 12-48 NC +/+ +/+ 13 Methyl methacrylate 80-62-6 Liq AOO 90 1 45-100 NC +/+ +/+ 14 Chlorobenzene 108-90-7 Liq AOO 25 1 NA NA -/- -/* 15 ...
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GMM-04: Genetically Modified Model Report on Pentaerythritol... 5.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm04_508.pdf
... Toxicology and Carcinogenesis Studies of Methyl Methacrylate (CAS No. 80-62-6) in F344/N Rats and B6C3F 1 Mice (Inhalation Studies). Technical Report Series No. 314. NIH ...
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TR-329: 1,2-Epoxybutane (CASRN 106-88-7) in F344/N Rats and B6C3F1Mice... 10.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr329.pdf
PROGRAM Technical Report Series No. 329 .r' z TOXICOLOGY AND CARCINOGENESIS STUDIES OF 1,2-EPOXYBUTANE (CAS NO. 106-88-7) IN F344/N RATS AND B6C3F1 MICE (INHALATION STUDIES) U.S. ...
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TR-363: Bromoethane (Ethyl Bromide) (CASRN 74-96-4) in F344/N... 10.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr363.pdf
No. 363 TOXICOLOGY AND CARCINOGENESIS STUDIES OF BROMOETHANE (ETHYL BROMIDE) (CAS NO. 74-96-4) IN F344/N RATS AND B6C3F1 MICE (INHALATION STUDIES) U.S. DEPARTMENT OF HEALTH AND ...
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TR-375: Vinyl Toluene (Mixed Isomers) (65%meta-isomer and 32... 20.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr375.pdf
PROGRAM Technical Report Series No. 375 (1- <~ TOXICOLOGY AND CARCINOGENESIS STUDIES OF VINYL TOLUENE (MIXED ISOMERS) (65%-71% META-ISOMER AND 32%-35% PARA-ISOMER) (CAS NO. ...
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TR-377: CS2 (94 o-Chlorobenzalmalononitrile, CASRN 2698-41-1... 12.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr377.pdf
7 TOXICOLOGY AND CARCINOGENESIS STUDIES OF CS2 (94% o-CHLOROBENZALMALONONITRILE, CAS NO. 2698-41-1) IN F344/N RATS AND B6C3Fi MICE (INHALATION STUDIES) U.S. DEPARTMENT OF HEALTH ...
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TR-438: Benzethonium Chloride (CASRN 121-54-0) in F344/N Rats... 10.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr438.pdf
8 TOXICOLOGY AND CARCINOGENESIS STUDIES OF BENZETHONIUM CHLORIDE (CAS NO. 121-54-0) IN F344/N RATS AND B6C3Fl MICE (DERMAL STUDIES) U.S. DEPARTMENT OF HEALTH A N D HUMAN SERVICES ...
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ICCVAM Evaluation of In Vitro Test Methods for Assessing Dermal... 3.1MB
https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/cwgfinal02/cwgfinal.pdf
NIH Publication No: 02-4502 ICCVAM Evaluation of EPISKIN(tm), EpiDerm(tm) (EPI-200), and the Rat Skin Transcutaneous Electrical Resistance (TER) Assay: In Vitro Test Methods for ...
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Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf
The Murine Local Lymph Node Assay: A Test Method for Assessing the Allergic Contact Dermatitis Potential of Chemicals/Compounds The Results of an Independent Peer Review Evaluation ...
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CERHR Monograph: Methylphenidate 11.6MB
https://ntp.niehs.nih.gov/ntp/ohat/stimulants/methylphenidate/methylphenidatemonograph.pdf
Methylphenidate August 2005 NIH Publication No. 05 - 4473 iii Table of ConTenTs Preface......
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TOX-93: Toxicity Study of Chitosan (CASRN 9012-76-4) Administered... 2.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox093_508.pdf
STudy of chiToSaN (caSRN 9012-76-4) admiNiSTeRed iN feed To SPRague dawley [cRl:cd(Sd)] RaTS NTP TOX 93 DECEMBER 2017 NTP Technical Report on the Toxicity Study of Chitosan (CASRN ...
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Background Review Document: In Vitro Test Methods for Assessing... 2.4MB
https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/epis_brd0801.pdf
Episkin(tm), EpiDerm(tm), and Rat Skin Transcutaneous Electrical Resistance (TER) In Vitro Test Methods for Assessing the Dermal Corrosivity Potential of Chemicals Background ...
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TR-371: Toluene (CASRN108-88-3) in F344/N Rats and B6C3F1Mice... 15.6MB
https://ntp.niehs.nih.gov/go/tr371
PROGRAM Technical Report Series No. 371 TOXICOLOGY AND CARCINOGENESIS STUDIES OF TOLUENE (CAS NO. 108-88-3) IN F344/N RATS AND B6C3Fi MICE (INHALATION STUDIES) U.S. DEPARTMENT OF ...
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CERHR Monograph: Potential Human Reproduction Effects of Styrene 6.0MB
https://ntp.niehs.nih.gov/ntp/ohat/styrene/styrene_monograph.pdf
Styrene February 2006 NIH Publication No. 06 - 4475 iii Table of ConTenTs Preface......
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TR-582: Vinylidene Chloride (CASRN 75-35-4) in F344/N Rats and... 5.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr582_508.pdf
oN The Toxicology aNd caRciNogeNesis sTudies of ViNylideNe chloRide (casRN 75-35-4) iN f344/N RaTs aNd B6c3f1/N Mice (iNhalaTioN sTudies) NTP TR 582 AUGUST 2015 NTP Technical ...
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Technical Reports 903KB
https://ntp.niehs.nih.gov/publications/reports/tr
... PDF (11.42 MB) Toxicology and Carcinogenesis Studies of Methyl Methacrylate (CASRN 80-62-6) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) 1986 Technical Report TR-313 PDF ...
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ICCVAM Report: Corrositex: An In Vitro Method for Assessing Dermal... 5.1MB
https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/corprrep.pdf
i Corrositex ® : An In Vitro Test Method for Assessing Dermal Corrosivity Potential of Chemicals The Results of an Independent Peer Review Evaluation Coordinated by the ...