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TR-479: Coconut Oil Acid Diethanolamine Condensate (CASRN 68603... 7.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr479.pdf
OF COCONUT OIL ACID DIETHANOLAMINE CONDENSATE (CAS NO. 68603-42-9) IN F344/N RATS AND B6C3F 1 MICE (DERMAL STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle ...
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TR-426: Corn Oil, Safflower Oil, and Tricaprylin (CASRNs. 8001... 18.8MB
https://ntp.niehs.nih.gov/go/tr426
2 Selected Oral Gavage Vehicles, NTP TR 426 *! i l CONTRIBUTORS National Toxicology Program Evaluated and interpreted results and reported findings C.J. Alden, Ph.D. G.A. Boorman, ...
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TOX-86: Toxicity Studies of Cedarwood Oil (Virginia) (CASRN 8000... 5.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox086_508.pdf
cedaRwood oil (ViRgiNia) (caSRN 8000-27-9) admiNiSTeRed deRmally To f344/N RaTS aNd B6c3f1/N mice NTP TOX 86 NOVEMBER 2016 NTP Technical Report on the Toxicity Studies of Cedarwood ...
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TOX-12: Castor Oil (CASRN 8001-79-4) 367KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox012.pdf
N T P T E C H N I C A L R E P O R T O N T H E TOXICI TY STUDIES OF CASTOR OIL IN F344/N RATS AND B6C3F 1 MICE (DOSED FEED STUDIES) R i c h a r d I r w i n, P h . D . , S t u d y S ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 196KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/micegavcornoil.pdf
4 Contract/Lab: All Laboratories Tumor Incidence for Selected Control Animal Groups Report Date: 05/04/2011 Species: MICE Route: GAVAGE Strain: B6C3F1 Vehicle: CORN OIL Length of ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 100KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/mice_gavco_path_hist09.pdf
0504 05/09/02 728 50 (1) 39(688) 56.7 Isoeugenol Battelle Columbus Laboratory 052000706 08/24/04 730 50 (1) 34(689) 56.4 Kava kava extract Battelle Columbus Laboratory 059902304 ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 100KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/rats_gavco_path_hist09.pdf
0503 04/22/02 729 50 (3) 35(702) 521.9 Isoeugenol Battelle Columbus Laboratory 052000705 08/18/04 727 49 (3) 34(692) 515.2 Kava kava extract Battelle Columbus Laboratory 059902303 ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 160KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/gavcornoilmice2010mar.pdf
2/2010 Species: MICE Route: GAVAGE Strain: B6C3F1 Vehicle: CORN OIL Length of Study: CHRONIC Study Summary Laboratory Name Study Number Study Start Date Length of Study in Days ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 157KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/gavcornoilrats2010mar.pdf
0/2010 Species: RATS Route: GAVAGE Strain: F 344/N Vehicle: CORN OIL Length of Study: CHRONIC Study Summary Laboratory Name Study Number Study Start Date Length of Study in Days ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 166KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/ratsgavcornoil.pdf
4 Contract/Lab: All Laboratories Tumor Incidence for Selected Control Animal Groups Report Date: 05/18/2011 Species: RATS Route: GAVAGE Strain: F 344/N Vehicle: CORN OIL Length of ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 162KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/micegavcornoil2013_508.pdf
Version: Jun2013 Toxicology Data Management System Page: 4 Contract/Lab: All Laboratories Tumor Incidence for Selected Control Animal Groups Report Date: 06/05/2013 Species: MICE ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 260KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/path_micegavcornoil2014_508.pdf
Contract/Lab: All Laboratories Tumor Incidence for Selected Control Animal Groups Report Date: 11/11/2014 Species: MICE Route: GAVAGE Strain: B6C3F1 Vehicle: CORN OIL Length of ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 113KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/ratsf344gavcornoil2013_508.pdf
4 Contract/Lab: All Laboratories Tumor Incidence for Selected Control Animal Groups Report Date: 06/05/2013 Species: RATS Route: GAVAGE Strain: F 344/N Vehicle: CORN OIL Length of ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 189KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/path_rathangavage_oil2014_508.pdf
4 Contract/Lab: All Laboratories Tumor Incidence for Selected Control Animal Groups Report Date: 11/11/2014 Species: RATS Route: GAVAGE Strain: Wistar Han Vehicle: CORN OIL Length ...
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Abstract for TOX-86 75KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox086
6abs Abstract for TOX-86 Toxicity Studies of Cedarwood Oil (Virginia) Administered Dermally to F344/N Rats and B6C3F1/N Mice CASRN: 8000-27-9 Synonyms/Common Names: Cedar oil; ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 78KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/whanratsgavcornoil2013_508.pdf
Version: Jun2013 Toxicology Data Management System Page: 4 Contract/Lab: All Laboratories Tumor Incidence for Selected Control Animal Groups Report Date: 06/12/2013 Species: RATS ...
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Abstract for TR-479 76KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr479
9abs Abstract for TR-479 Toxicology and Carcinogenesis Studies of Coconut Oil Acid Diethanolamine Condensate in F344/N Rats and B6C3F1 Mice (Dermal Studies) CASRN: 68603-42-9 ...
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Historical Controls: Pathology Tables by Gavage/Corn Oil for... 59KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/hiscont2013_hsd_gavage_cornoil_508.pdf
Version: Jun2013 Toxicology Data Management System Page: 4 Contract/Lab: All Laboratories Tumor Incidence for Selected Control Animal Groups Report Date: 06/17/2013 Species: RATS ...
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Abstract for TOX-12 60KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox012
2abs Abstract for TOX-12 Toxicity Studies of Castor Oil in F344/N Rats and B6C3F1 Mice (Dosed Feed Studies) CASRN: 8001-79-4 Chemical Formula: C57H104O9 Molecular Weight: 933.4396 ...
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TOX-14: p-Chloro-a,a,a-Trifluorotoluene (CASRN 98-56-6) 2.2MB
https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox014.pdf
National Toxicology Program Toxicity Report Series Number 14 NTP Technical Report on Toxicity Studies of p-Chloro-α α α α, , , ,α α α α, , , ,α α α α-Trifluorotoluene ...
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Castor Oil 55KB
https://ntp.niehs.nih.gov/publications/reports/tr/200s/tr290
90abs Castor Oil
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Abstract for TR-426 70KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr426
6abs Abstract for TR-426 Comparative Toxicology Studies of Corn Oil, Safflower Oil, and Tricaprylin in Male F344/N Rats as Vehicles for Gavage Substances: Corn oil (CASRN ...
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Abstract for TOX-56 67KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox056
6abs Abstract for TOX-56 Toxicity Studies of Carisoprodol Administered by Gavage to F344/N Rats and B6C3F1 Mice CASRN: 78-44-4 Chemical Formula: C12H24N2O4 Molecular Weight: 260.33 ...
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Target Organs and Levels of Evidence for TR-426 58KB
https://ntp.niehs.nih.gov/data/tr/400s/tr426levels
390 Target Organs and Levels of Evidence for TR-426 Comparative Toxicology Studies of Corn Oil, Safflower Oil, and Tricaprylin (CASRNs 8001-30-7, 8001-23-8, and 538-23-8) in Male ...
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Historical Controls: Survival Gavage Corn Oil Wistar Han Rats 159KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/rats_gavage_oil_surv_508.pdf
a.9 Historical Control Survival for Gavage/Com Oil Studies Male Rats/WIStar Han 2 studies 1.a a.a a.7 ~ ~ Cl) a.6 e:s ~ a.5 a.4 ~ a.3 ~ a.2 a.1 a.a 1.0 a.9 I a.a a.7 Cl) a.6 e:s ...
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Historical Controls: Body Weights Gavage Corn Oil Wistar Han... 197KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/rats_gavage_oil_body_508.pdf
Historical Control Body Weights for Gavage/Com Oil Studies Male Rats/WIStar Han 2 studies ~ ~ ~ ~ ~ 0 i:Il ~ ~ ~ ~ ~ ~ a i:Il ~ - 5th Percentile (Lower Llne) - Mean Body Weight ...
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Historical Controls: Body Weights Gavage Corn Oil for Mice 175KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/mice_gavage_cornoil_body_508.pdf
Body Weights for Gavage/Com Oil Studies Male Mice/B6C3F1 6 studies - 5th Percentile (Lower Llne) - Mean Body Weight {Middle Line) - 95th Percentile (Upper Llne) 100 90 I 80 70 I?; ...
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Historical Controls: Survival for Gavage Corn Oil for Mice 161KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/mice_gavage_cornoil_surv_508.pdf
Survival for Gavage/Com Oil Studies Male Mice/B6C3F1 6 studies 1.0 0.9 I 0.8 0.7 CIJ 0.6 I ~ 0.5 0.4 0.3 0.2 0.1 a.a 1.0 0.9 I 0.8 0.7 CIJ 0.6 ~ ; 0.5 0.4 0.3 ~ 0.2 0.1 0.0 - - - ...
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TR-479: Data 59KB
https://ntp.niehs.nih.gov/data/tables/tr/400s/tr479
8792 TR-479: Data TR-479 Coconut Oil Diethanolamine Pathology Tables - Rats P03 - Incidence Rates of Non-Neoplastic Lesions P04 - Neoplasms by Individual Animal P05 - Incidence ...
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Historical Controls: Growth Curves by Gavage/Corn Oil for B6C3F1... 240KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/mice_gavage_cornoil_body.pdf
100 90 80 70 --. -. -.. ------. -. -. -.. ----.... -. -. -.- --. -.... -. -- .- . -. -. - I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I I - - . - . - ~ - - - ~ . - ...
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Historical Controls: Survival Curves by Gavage/Corn Oil for B6C3F1... 234KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/mice_gavage_cornoil_surv.pdf
0.9 0.8 0.7 0.6 0.5 0.4 . 03 0.2 0.1 0.0 to t===f===~~====~-~~--~ -- :- ~ --~-~~-~--~--:-:~--~--~--l ~ 0 0 0 . 0 0 . 0 0 0 . 0 0 . 0 0 0 . 0 0 . 0 0 0 . 0 0 . . . . . . . . . :. . ...
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Historical Controls: Growth Curves by Gavage/Corn Oil for Fischer... 262KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/rats_gavage_cornoil_body.pdf
- - - 700 650 600 550 ~ 500 ~ 450 5 400 ...... 350 ~ 8 300 250 ~ 200 150 ~ 100 50 700 650 {/) 600 550 ~ 500 ~ 450 5 400 ~ 350 300 8 250 ~ 200 150 ~ 100 50 0 - 5th Percentile ...
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Historical Controls: Survival Curves by Gavage/Corn Oil for Fischer... 235KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/rats_gavage_cornoil_surv.pdf
- 0.8 ~ 0.7 t/.l 0.6 I ~ 0.5 0.4 0.3 0.2 0.1 0.0 1.0 0.9 0.8 0.7 ~ t/.l 0.6 ~ 0.5 0.4 ~ ; 0.3 0.2 0.1 0.0 - - - lDW8I 95% Confidence LimiliLowm Lim!) - - - Survival Probabilily ...
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Historical Controls: Growth Curves by Gavage/Corn Oil for Harlan... 122KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/sdrats_gavage_cornoil_body.pdf
Control Body Wllights for Gavage/Corn Oil Studies Male Rats 1 study - 5th Percenilio (Low"," Line) - Mean Body weight (Middle Une) - 95th _ l I l e (Upper Une) iOO l/l 650 600 ~ ...
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Historical Controls: Survival Curves by Gavage/Corn Oil for Harlan... 99KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/sdrats_gavage_cornoil_surv.pdf
Centrol Survival for Gavage/Corn Oil Studies Male Rats 1 study - lower 95% Conldence limit (lower line) - Su..tval Probability (Middle Une) - Upper 95% Conldence Umlt (Upper Une) ...
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Historical Controls: Growth Curves by Gavage/Corn Oil for B6C3F1... 195KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/mice_gavage_cornoil_body_508.pdf
Historical Control Body Weights for Gavage/Corn Oil Studies Male Mice/B6C3F1 5 studies - 5th Percentile (Lower Line) - Mean Body Weight (Middle Line) - 95th Percentile (Upper Line) ...
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Historical Controls: Survival Curves by Gavage/Corn Oil for B6C3F1... 185KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/mice_gavage_cornoil_surv_508.pdf
- - - Lower ~ ConfIdence Ltmit (Low8r Line) - - - s_"" ""'_ [MlddIo IJno) - - - Uppsr 95'36 Con:fldtmce UmIt [Uppl/ll' Line) I '" ~ 5 ~ ~ 1.0 0.9 0.8 0.7 0.6 0.5 0.4 0.3 0.2 0.1 ...
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Historical Controls: Growth Curves by Gavage/Corn Oil for Fischer... 211KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/rats_gavage_cornoil_body_508.pdf
5th Percentile (Lower Line) - Mean Body Weight (Middle Line) - 95th Percentile (Upper Line) 700 650 ~ 600 550 500 ~ 5 450 400 ~ 350 300 is 250 0 ~ ~ 200 150 WO 50 0 0 15 30 45 60 ...
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Historical Controls: Survival Curves by Gavage/Corn Oil for Rats... 187KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/rats_gavage_cornoil_surv_508.pdf
1.0 0.9 I 0.8 0.7 '" 0.6 5 ~ 0.5 0.4 ~ 0.3 ~ 0.2 0.1 0.0 , , , , , 0 15 30 45 60 75 90 105 120 WEEKS ON STIJDY - - - - - - s_"" Lower ~ ""'_ ConfIdence Ltmit (Low8r Line) [MlddIo ...
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Historical Controls: Growth Curves by Gavage/Corn Oil for B6C3F1... 124KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/mice_gavage_cornoil_body_2011.pdf
- 5th Percentile (Lower Line) - Mean Body Weight (Middle Une) - 95th Percentile (Upper Line) 100 90 ~ 80 70 ~ 5 60 ~ 50 E5 40 0 I:l:l 30 ~ 20 10 0 0 15 30 45 60 75 90 105 120 WEEKS ...
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Historical Controls: Survival Curves by Gavage/Corn Oil for B6C3F1... 118KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/mice_gavage_cornoil_surv_2011.pdf
Historical Control Survival for Gavage/Com Oil Studies Male Mice/B6C3F1 7 studies - - - Lower 95% Confidence Umll (Lower Une) - - - Smvlval Probabillty [Middle Una) - - - Upper 95% ...
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Historical Controls: Growth Curves by Gavage/Corn Oil for Fischer344N... 184KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/f344nratsgavcornoil_body_2013_508.pdf
5th Percentile (Lower Line) - Mean Body Weight {Middle Line) - 95th Percentile (Upper Line) 700 650 tf.l 600 ~ 550 500 ~ 450 5 400 ...... 350 ~ ~ 300 0 250 r:Q 200 ~ 150 100 50 0 0 ...
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Historical Controls: Survival Curves by Gavage/Corn Oil for Fischer344... 163KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/f344nratsgavcornoil_surv_2013_508.pdf
- - Lower 95% Confidence Liurlt (Lower Line) Survival Probability (Middle Line) - - - Upper 95% Confidence Liurlt (Upper Line) Historical Control Survival for Gavage/Corn Oil ...
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Historical Controls: Growth Curves by Gavage/Corn Oil for Harlan... 188KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/hsdratsgavcornoil_body_2013_508.pdf
5th Percentile (Lower Line) - Mean Body Weight {Middle Line) - 95th Percentile (Upper Line) 700 650 tf.l 600 ~ 550 500 ~ 450 5 400 ...... 350 ~ ~ 300 0 250 r:Q 200 ~ 150 100 50 0 0 ...
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Historical Controls: Survival Curves by Gavage/Corn Oil for Harlan... 175KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/hsdratsgavcornoil_surv_2013_508.pdf
- - Lower 95% Confidence Liurlt (Lower Line) - - - Survival Probability (Middle Line) - - - Upper 95% Confidence Liurlt (Upper Line) Historical Control Survival for Gavage/Corn Oil ...
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Historical Controls: Body Weights for Gavage/Corn Oil Studies... 97KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2015/m_gavage_cornoil_bodywt2015_508.pdf
Historical Control Body Weights for Gavage/Com Oil Studies Male Mice/B6C3F1 4 studies - 5th Percentile (Lower Llne) - Mean Body Weight {Middle Line) - 95th Percentile (Upper Llne) ...
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Nomination Background: p-Synephrine (CASRN: 94-07-5) 1.3MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/bitterorange_508.pdf
Bitter Orange (Citrus aurantium var. amara) Extracts and Constituents (±)-p-Synephrine [CAS No. 94-07-5] and (±)-p-Octopamine [CAS No. 104-14-3] Review of Toxicological ...
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Abstract for TER87118 59KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter87118
8abs Abstract for TER87118 Teratologic Evaluation of Corn Oil or Distilled Water Administered to CD Rats on Gestational Days 6 Through 15 CASRN: 8001-30-7 Report Date: Jan. 25, ...
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Abstract for TER87119 60KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter87119
9abs Abstract for TER87119 Teratologic Evaluation of Corn Oil and Distilled Water Administered by Gavage to CD-1 Mice on Gestational Days 6 Through 15 CASRN: 8001-30-7 Report Date: ...
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Abstract for TOX-76 64KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox076
6abs Abstract for TOX-76 Toxicity Studies of 2,4-Decadienal Administered by Gavage to F344/N Rats and B6C3F1 Mice CASRN: 25152-84-5 Chemical Formula: C10H16O Molecular Weight: ...
