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Search suggestions for "822-36-6".

  1. CEBS Data Related to 4-Methylimidazole (822-36-6) https://cebs.niehs.nih.gov/cebs/test_article/822-36-6


62 results found for "822-36-6".

  1. TR-535: 4-Methylimidazole (CASRN 822-36-6) in F344/N Rats and... 10.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr535.pdf

    4-METHYLIMIDAZOLE (CAS NO. 822-36-6) IN F344/N RATS AND B6C3F 1 MICE (FEED STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 January 2007 NTP TR ...

  2. TOX-67: 2-Methylimidazole and 4-Methylimidazole 5.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox067.pdf

    NTP Technical Report on the Toxicity Studies of 2- and 4-Methylimidazole (CAS No. 693-98-1 and 822-36-6) Administered in Feed to F344/N Rats and B6C3F 1 Mice April 2004 NIH ...

  3. Public Comment: 4-Methylimidazole; Joseph Rodricks; RoC; Sept... 157KB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2013/publiccomm/rodricks20131018_508.pdf

    Information on 4-Methylimidazole Submitted to the National Toxicology Program (NTP) ... to submit information on 4-methylimidazole (4-MeI, CAS No. 822-36-6) to the ...

  4. Abstract for TR-535 68KB

    https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr535

    Abstract for TR-535 Toxicology and Carcinogenesis Studies of 4-Methylimidazole in F344/N Rats and B6C3F1 Mice (Feed Studies) CASRN: 822-36-6 Chemical Formula: C4H6N2 Molecular ...

  5. Abstract for TOX-67 70KB

    https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox067

    Toxicity Studies of 2- and 4-Methylimidazole Administered in Feed to F344/N Rats and B6C3F1 Mice Substances: 2-Methylimidazole (CASRN 693-98-1) 4-Methylimidazole (CASRN 822-36-6) ...

  6. Public Comment: 4-Methylimidazole; Forrest L. Bayer; RoC; Sept... 72KB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2013/publiccomm/bayer20131017_508.pdf

    Among the substances nominated to the RoC is 4-Methylimidazole ("4MEI"). As you may know, 4MEI is a constituent of caramel color. The American Beverage Association ("ABA") has ...

  7. Target Organs and Levels of Evidence for TR-535 59KB

    https://ntp.niehs.nih.gov/data/tr/500s/tr535levels

    Target Organs and Levels of Evidence for TR-535 Toxicology and Carcinogenesis Studies of 4-Methylimidazole (CASRN 822-36-6) in F344/N Rats and B6C3F1 Mice (Feed Studies) Chemical ...

  8. Minutes: BSC TRRS; Sept. 27, 2005 1.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2005/sept/trrs27sept2005mins_508.pdf

    ......... 13 4-Methylimidazole ......different from that proposed in the 4-methylimidazole study and suggested equivocal ...

  9. Historical Controls: Pathology Tables by Feed for Mice 100KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/mice_feed_path_hist09.pdf

    02/03/00 729 50 (1) 45(717) 46.1 4-Methylimidazole Southern Research Institute ... 02/03/00 734 50 (5) 42(706) 45.6 4-Methylimidazole Southern Research Institute ...

  10. Historical Controls: Pathology Tables by Oral/Feed for Fischer... 101KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/rats_feed_path_hist09.pdf

    01/20/00 730 50 (3) 31(702) 448.0 4-Methylimidazole Southern Research Institute ... 01/20/00 735 50 (5) 40(702) 311.3 4-Methylimidazole Southern Research Institute ...

  11. Historical Controls: Chemicals by Species/Route/Vehicle for Fischer... 206KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009_byroute.pdf

    Milk thistle extract Mice Oral Feed 4-Methylimidazole Mice Oral Feed Goldenseal root ... Milk thistle extract Rats Oral Feed 4-Methylimidazole Rats Oral Feed Goldenseal root ...

  12. Agenda: BSC TRRS; Sept. 27-28, 2005 83KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2005/sept/trrs27sept2005agenda_508.pdf

    and preparation of coatings; Dermal, p53 haploinsufficient female mice 4-Methylimidazole/ 822-36-6 TR 535 Manufacture of pharmaceuticals, dyes, agricultural chemicals and ...

  13. Historical Controls: All Routes and Vehicles for Mice; Studies... 211KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/m_hcrpt_allrte20071000_508.pdf

    ... 02/03/00 729 50(1) 45(717) 46.1 4-Methylimidazole Battelle Northwest 058800604 07/30/... 02/03/00 734 50(5) 42(706) 45.6 4-Methylimidazole Battelle Northwest 058800604 07/30/...

  14. Historical Controls: All Routes and Vehicles for Rats; Studies... 252KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/r_hcrpt_allrte20070300_508.pdf

    ... 01/20/00 730 50(3) 31(702) 448.0 4-Methylimidazole Battelle Northwest 058800603 08/06/... 01/20/00 735 50(5) 40(702) 311.3 4-Methylimidazole Battelle Northwest 058800603 08/06/...

  15. Historical Controls: All Routes and Vehicles for Rats; Studies... 225KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/r_hcrpt_allrte20071000_508.pdf

    ... 01/20/00 730 50(3) 31(702) 448.0 4-Methylimidazole Battelle Northwest 058800603 08/06/... 01/20/00 735 50(5) 40(702) 311.3 4-Methylimidazole Battelle Northwest 058800603 08/06/...

  16. Historical Controls: All Route and Vehicles for Rats; Studies... 162KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2008/r_hcrtp_allrte_20081100.pdf

    ... 01/20/00 730 50 (3) 31(702) 448.0 4-Methylimidazole Battelle Northwest 058800603 08/06/... 01/20/00 735 50 (5) 40(702) 311.3 4-Methylimidazole Battelle Northwest 058800603 08/06/...

  17. Spleen - Congestion - Nonneoplastic Lesion Atlas 289KB

    https://ntp.niehs.nih.gov/atlas/nnl/immune-system/spleen/Congestion

    National Toxicology Program. 2007. NTP TR-535. Toxicology and Carcinogenesis Studies of 4-Methylimidazole (CAS No. 822-36-6) in F344/N Rats and B6C3F1 Mice (Feed Studies). NTP, ...

  18. Spleen, Red Pulp - Hyperplasia, Stromal - Nonneoplastic Lesion... 290KB

    https://ntp.niehs.nih.gov/atlas/nnl/immune-system/spleen/RedPulp-HyperplasiaStromal

    National Toxicology Program. 2007. NTP TR-535. Toxicology and Carcinogenesis Studies of 4-Methylimidazole (CAS No. 822-36-6) in F344/N Rats and B6C3F1 Mice (Feed Studies). NTP, ...

  19. Spleen - Congestion 368KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/immune/spleen/congest/spleen-congestion-pdf_508.pdf

    References: National Toxicology Program. 2007. NTP TR-535. Toxicology and Carcinogenesis Studies of 4- Methylimidazole (CAS No. 822-36-6) in F344/N Rats and B6C3F1 Mice (Feed ...

  20. Historical Controls: All Routes and Vehicles for Mice; Studies... 255KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2006/m_hcrpt_allrte2006_508.pdf

    ... 02/03/00 729 50(1) 45(717) 46.1 4-Methylimidazole Battelle Northwest 058800604 07/30/... 02/03/00 734 50(5) 42(706) 45.6 4-Methylimidazole Battelle Northwest 058800604 07/30/...

  21. Historical Controls: All Routes and Vehicles for Rats; Studies... 270KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2006/r_hcrpt_allrte2006_508.pdf

    ... 01/20/00 730 50(3) 31(702) 448.0 4-Methylimidazole Battelle Northwest 058800603 08/06/... 01/20/00 735 50(5) 40(702) 311.3 4-Methylimidazole Battelle Northwest 058800603 08/06/...

  22. Historical Controls: All Routes and Vehicles for Mice; Studies... 317KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/m_hcrpt_allrte20070300_508.pdf

    ... 02/03/00 729 50(1) 45(717) 46.1 4-Methylimidazole Battelle Northwest 058800604 07/30/... 02/03/00 734 50(5) 42(706) 45.6 4-Methylimidazole Battelle Northwest 058800604 07/30/...

  23. Historical Controls: Pathology Tables for All Routes/Vehicles... 176KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009-05-14-hist-miceallroutes.pdf

    ... 02/03/00 729 50 (1) 45(717) 46.1 4-Methylimidazole Battelle Northwest 058800604 07/30/... 02/03/00 734 50 (5) 42(706) 45.6 4-Methylimidazole Battelle Northwest 058800604 07/30/...

  24. Historical Controls: Pathology Tables for All Routes/Vehicles... 174KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009-05-14-hist-ratsallroutes.pdf

    ... 01/20/00 730 50 (3) 31(702) 448.0 4-Methylimidazole Battelle Northwest 058800603 08/06/... 01/20/00 735 50 (5) 40(702) 311.3 4-Methylimidazole Battelle Northwest 058800603 08/06/...

  25. Lymph node - Sinus Erythrocytosis - Nonneoplastic Lesion Atlas 289KB

    https://ntp.niehs.nih.gov/atlas/nnl/immune-system/lymph-node/SinusErythrocytosis

    ... National Toxicology Program. 2007. NTP TR-535. Toxicology and Carcinogenesis Studies of 4-Methylimidazole (CAS No. 822-36-6) in F344/N Rats and B6C3F1 Mice (Feed Studies). NTP, ...

  26. Spleen, Red Pulp - Hyperplasia, Stromal 517KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/immune/spleen/rphyps/spleen-red-pulp-hyperplasia-stromal-pdf_508.pdf

    .../16207 National Toxicology Program. 2007. NTP TR-535. Toxicology and Carcinogenesis Studies of 4- Methylimidazole (CAS No. 822-36-6) in F344/N Rats and B6C3F1 Mice (Feed Studies). ...

  27. Lymph Node - Sinus Erythrocytosis 776KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/immune/lymph_node/serythroc/lymph-node-sinus-erythrocytosis-pdf_508.pdf

    ... National Toxicology Program. 2007. NTP TR-535. Toxicology and Carcinogenesis Studies of 4- Methylimidazole (CAS No. 822-36-6) in F344/N Rats and B6C3F1 Mice (Feed Studies). ...

  28. Public Comments for Ongoing & Considered Health Effects Evaluations 91KB

    https://ntp.niehs.nih.gov/whatwestudy/assessments/comments

    ... Technical Caramel Association 4-Methylimidazole Cancer Effects Sep 20, 2013 Federal ... of American Beverage Association 4-Methylimidazole Cancer Effects Sep 20, 2013 Federal ...

  29. Adrenal glands - Accessory Adrenocortical Nodule - Nonneoplastic... 299KB

    https://ntp.niehs.nih.gov/atlas/nnl/endocrine-system/adrenal-gland/AccessoryAdrenocorticalNodule

    ... National Toxicology Program. 2007. NTP TR-535. Toxicology and Carcinogenesis Studies of 4- Methylimidazole (CAS No. 822-36-6) in F344/N Rats and B6C3F1 Mice (Feed Studies). NTP, ...

  30. Lymph node - Inflammation - Nonneoplastic Lesion Atlas 293KB

    https://ntp.niehs.nih.gov/atlas/nnl/immune-system/lymph-node/Inflammation

    ... National Toxicology Program. 2007. NTP TR-535. Toxicology and Carcinogenesis Studies of 4-Methylimidazole (CAS No. 822-36-6) in F344/N Rats and B6C3F1 Mice (Feed Studies). NTP, ...

  31. Lymph Node - Inflammation 1.4MB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/immune/lymph_node/inflamm/lymph-node-inflammation-pdf_508.pdf

    ... National Toxicology Program. 2007. NTP TR-535. Toxicology and Carcinogenesis Studies of 4- Methylimidazole (CAS No. 822-36-6) in F344/N Rats and B6C3F1 Mice (Feed Studies). ...

  32. Adrenal Gland - Accessory Adrenocortical Nodule 432KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/endocrine/adrenal/acnodule/adrenal-gland-accessory-adrenocortical-nodule-pdf_508.pdf

    ... National Toxicology Program. 2007. NTP TR-535. Toxicology and Carcinogenesis Studies of 4- Methylimidazole (CAS No. 822-36-6) in F344/N Rats and B6C3F1 Mice (Feed Studies). ...

  33. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... No Evidence NE No Evidence NE No Evidence NE No Evidence TR-535 09/28/05 4-Methylimidazole 822-36-6 NE No Evidence EE Equivocal Evidence CE Clear Evidence P Clear Evidence TR-534 ...

  34. TR-516: 2-Methylimidazole (CASRN 693-98-1) in F344/N Rats and... 9.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr516.pdf

    ... nary review of tissues from studies on the related chem- ical 4-methylimidazole. Dr. ... Both 2-methylimidazole and 4-methylimidazole were nomi- nated by the National Cancer ...

  35. Short-Term Toxicity Reports 224KB

    https://ntp.niehs.nih.gov/publications/reports/tox

    ... TOX-67 PDF (1.62 MB) Toxicity Studies of 2-Methylimidazole and 4-Methylimidazole (CASRNs 693-98-1 and 822-36-6) Administered in Feed to F344/N Rats and B6C3F1 Mice 2004 Short-Term ...

  36. Minutes: BSC TRRS; May 22, 2003 842KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2003/may/trrs22may2003mins_508.pdf

    ... and spleen were considered treatment related, and that a similar effect was seen in a preliminary review of tissues from studies on the related chemical 4-methylimidazole. Dr. ...

  37. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... Report TR-535 PDF (10.37 MB) Toxicology and Carcinogenesis Studies of 4-Methylimidazole (CASRN 822-36-6) in F344/N Rats and B6C3F1 Mice (Feed Studies) 2007 Technical Report TR-534 ...

  38. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... Report TR-535 PDF (10.37 MB) Toxicology and Carcinogenesis Studies of 4-Methylimidazole (CASRN 822-36-6) in F344/N Rats and B6C3F1 Mice (Feed Studies) 2007 Technical Report TR-534 ...

  39. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... TR-535 PDF (10.37 MB) Toxicology and Carcinogenesis Studies of 4-Methylimidazole (CASRN 822-36-6) in F344/N Rats and B6C3F1 Mice (Feed Studies) 2007 Long-Term ...

  40. TR-537: Dibromoacetic Acid (CASRN 631-64-1) in F344/N Rats and... 9.3MB

    https://ntp.niehs.nih.gov/go/tr537

    ... 4-methylimidazole study and sug- gested equivocal evidence might be more appropriate. Dr. Elwell noted that the statistical support was slightly stronger for the 4-methylimidazole ...

  41. TR-562: Goldenseal Root Powder (GOLDENSEALRT) in F344/N Rats... 6.4MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr562.pdf

    ... Goldenseal root powder 1/50 1/50 4-Methylimidazole 0/50 0/50 Milk thistle extract 3/50 ... 20/50 Goldenseal root powder 8/50 4-Methylimidazole 16/49 Milk thistle extract 13/50 ...

  42. TR-184: Nitrofen (CASRN 1836-75-5) 4.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr184.pdf

    ... NUMBER OF ANIMALS NECROPSIED ** EXCLUDES PARTIALLY AUTOLYZED ANIMALS EIGE DOSE 22-2141 50 2 48 48 (48) 1 (2%) (46) ' 2 (4%) 1 (238) (48) 1 (2*) (44) 1 12%) <<*7) (48) 4 mi, . . . ...

  43. Public Health Impact 1.5MB

    https://ntp.niehs.nih.gov/media/impact

    ... January 7, 2011 as Known to the State of California to Cause Cancer: 4-Methylimidazole 4-Methylimidazole meets the criteria for listing as known to the State to cause cancer ...

  44. TR-550: Cresols (CASRN 1319-77-3) in Male F344/N Rats and Female... 3.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr550.pdf

    ... cresols and cresol mixtures totaled 132.4 million pounds in 1984 (40 CFR, Part 799). ... Date of Last Exposure Rats: August 4, 2004 Mice: August 19, 2004 Necropsy Dates Rats: ...

  45. TR-556: Chromium Picolinate Monohydrate (CASRN 27882-76-4) in... 6.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr556.pdf

    ... 2002 Mice: July 26 to August 2, 2004 Mice: January 15 (males) or 14 (females), ... Necropsy Dates Rats: January 16 (males) or 17 (females), 2002 Rats: August 9-17, 2004 Mice...

  46. TR-203: Phenol for Possible Carcinogenicity (CASRN108-95-2) 4.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr203.pdf

    ... Program: 75°C for 5 min; 75 to 250 C at 10 C/minute Results: One homogeneous peak at 6.4 minutes System 2: Instrument: Bendix 2500 Detection:' Flame lonization Column: Chromosorb ...

  47. TR-523: Diisopropylcarbodiimide (CASRN 693-13-0) in F344/N Rats... 10.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr523.pdf

    ... 7 weeks Date of First Dose Rats: June 6, 1994 Mice: June 8, 1994 Duration of Dosing 16 days Date of Last Dose Rats: June 21, 1994 Mice: June 23, 1994 Necropsy Dates Rats: June ...

  48. Historical Controls: By Route and Vehicle for Mice; Studies started... 644KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/m_hcrpt_rte20071000_508.pdf

    ... 02/03/00 729 50(1) 45(717) 46.1 4-Methylimidazole Female Battelle Columbus Laboratory ... 02/03/00 734 50(5) 42(706) 45.6 4-Methylimidazole NOTE: The text on page 2 ("Report ...

  49. TOX-71: Malachite Green Chloride and Leucomalachite Green (CASRNs... 2.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox071.pdf

    ... 3,3N,4,4N-Tetrachloroazobenzene 65 3,3N,4,4N-Tetrachloroazoxybenzene 66 2- and 4-Methylimidazole 67 Butanal Oxime 69 p-tert-Butylcatechol 70 Malachite Green Chloride and ...

  50. Historical Controls: By Route and Vehicle for Rats; Studies started... 624KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/r_hcrpt_rte20071000_508.pdf

    ... 01/20/00 730 50(3) 31(702) 448.0 4-Methylimidazole Female Battelle Columbus Laboratory ... 01/20/00 735 50(5) 40(702) 311.3 4-Methylimidazole NOTE: The text on page 2 ("Report ...

 
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