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Search suggestions for "83-79-4".

  1. CEBS Data Related to Rotenone (83-79-4) https://cebs.niehs.nih.gov/cebs/test_article/83-79-4


124 results found for "83-79-4".

  1. TR-320: Rotenone (CASRN 83-79-4) in F344/N Rats and B6C3F1Mice... 11.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr320.pdf

    0 ¥- SERVI(£s (/e ~-.--~~ TOXICOLOGY AND CARCINOGENESIS STUDIES OF ROTENONE (CAS NO. 83-79-4) IN F344/N RATS AND B6C3Ft MICE (FEED STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN ...

  2. Abstract for TR-320 65KB

    https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr320

    Abstract for TR-320 Toxicology and Carcinogenesis Studies of Rotenone in F344/N Rats and B6C3F1 Mice (Feed Studies) CASRN: 83-79-4 Chemical Formula: C23H22O6 Molecular Weight: ...

  3. Target Organs and Levels of Evidence for TR-320 57KB

    https://ntp.niehs.nih.gov/data/tr/300s/tr320levels

    Target Organs and Levels of Evidence for TR-320 Toxicology and Carcinogenesis Studies of Rotenone (CASRN 83-79-4) in F344/N Rats and B6C3F1 Mice (Feed Studies) Chemical (Study ...

  4. Minutes: BSC TRRS; Aug. 19, 1986 686KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1986/aug/86aug19trrsmins_508.pdf

    h a l a t i o n Methyl Carbarnate Gavage Rotenone Feed Trichloroethylene Gavage ( 4 Rat S ... Perera seconded the motion and i t was approved unanimously M a t i v e votes. Rotenone. ...

  5. Developmental Neurotoxicity Health Effects Innovation Program... 3.4MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/bsc/2020/december/presentations/13behl_bsc_508.pdf

    ... Objective 1: Building on DNTP's Past Experience Aschner et al., 2017 & Mundy 2015 5- FU Paraquat Rotenone Colchicine Valproic acid Lead acetate BDE-99 , BDE-47, EHDP ...

  6. TOWARD VALIDATION OF A HUMAN IN... 1.1MB

    https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-15444/stemina/egnashposter-2014-wc.pdf

    ... NON 300 Pyridaben Environmental TER 0.006 Tetrabromobisphenol A Environmental NON 293 Rotenone Environmental TER 0.01 Triclopyr Environmental NON 300 Spiroxamine Environmental TER ...

  7. RR-16: Scoping Review of Paraquat Dichloride Exposure and Parkinson... 2.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr16_508.pdf

    ... associations for one or more, including rotenone, although adjustment for co-exposures ... Cuadrado A. 2007. Chronic inhalation of rotenone or paraquat does not induce Parkinson's ...

  8. Presentation: Setting the Stage: Purpose, Definitions, Scope... 2.1MB

    https://ntp.niehs.nih.gov/iccvam/meetings/ivive-wksp-2016/webinar-slides/1-wetmore-07oct2015-fd-508.pdf

    ... APR_MitoticArrest 1 1.4569 57-83-0 Progesterone 0.2007 APR_MitoMembPot 1 4.9835 83-79-4 Rotenone 0.3131 APR_MitoticArrest 1 3.1941 79902-63-9 Simvastatin 0.6379 ...

  9. Minutes: BSC; Feb. 5, 1998 713KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1998/february/19980205bscmins_508.pdf

    ... in Salmonella while resorcinol and rotenone were negative. p -Anisidine and ... Tg.AC. Topical exposure of Tg.AC mice to rotenone resulted in a systemic disease known as ...

  10. Protocol: Evidence Map of Inflammation-Based Atherosclerosis... 643KB

    https://ntp.niehs.nih.gov/sites/default/files/2023-07/protocol_atherosclerosis_supplementaljuly2023_508.pdf

    ... OR rodenticide*[tiab] OR rotenone[tiab] OR secondhand-smoke[tiab] OR ... radon OR repellent* OR rodenticide* OR rotenone OR secondhand-smoke OR second-hand-smoke ...

  11. Validation of an In Vitro Gastrointestinal Digestion and Co-culture... 19.2MB

    https://ntp.niehs.nih.gov/sites/default/files/2023-12/Wksp_06_Sayes_GutModels2023_508.pdf

    ... cell model used in this study .The positive control material used in this study was rotenone and it induced the least resistance Pro-inflammatory response via interleukin 6 ...

  12. In Vitro to In Vivo Extrapolation for Developmental Neurotoxicity... 1.7MB

    https://ntp.niehs.nih.gov/sites/default/files/2024-03/SOT2024-Kreutz-poster.pdf

    ... Heptachlor Methotrexate o,p-DDT Rotenone S-Bioallethrin Tebuconazole 10 -5 10 -4 ... ,5 -Diphe ny lhy da ntoin Tebuc ona zole Rotenone Em ame ctin benzoate Pir im iphos -me ...

  13. Developmental Neurotoxicity Assessment Using In Vitro Assays 6.8MB

    https://ntp.niehs.nih.gov/iccvam/meetings/commprac-2022/20220125-iccvam-cop-hogberg-508.pdf

    ... Valinomycin Bis(tributyhin)oxide Rotenone Meth~ mercuric (II) clllonde Berberine ... Valinomycin Bis(tributyhin)oxide Rotenone Meth~ mercuric (II) clllonde Berberine ...

  14. Comparison of devTOX quickPredict Assay With Other Methods 1.0MB

    https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2016-15444/stemina/comparisonspreadsheet-508.pdf

    ... DT NON Retinol 2.4 N/A N/A C NON NON (1) DT (3) DT (3) DT (2,6,14) NON (4) DT (7) NON NON Rotenone N/A N/A N/A n.d. DT n.d. DT (6) n.d. DT (5,12,14) n.d. n.d. DT DT Saccharin 1.4 ...

  15. Comparison of the Stemina devTOX quickPredict system with other... 2.1MB

    https://ntp.niehs.nih.gov/iccvam/pubcomment/fr-2018-09961/palmer-stemina-spreadsheet.pdf

    ... Retinol* NON A/C/X NON (1) DT (3) DT (3) DT (2,6,14) DT (4) DT (7) 0.84 NON NON 2.4 N/A N/A Exposure (Cmax) Human Rotenone DT n.d. n.d. DT (6) n.d. DT (5,12,14) n.d. n.d. 0.84 DT ...

  16. TR-388: Ethylene Thiourea (CASRN 96-45-7) in F344 Rats and B6C3F1Mice... 13.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr388.pdf

    ... 0/50 N-P henyl-2-Naphthylamine 1/50 Rotenone 1/50 I-Ascorbic Acid 1/50 Total 3 m ... N-Phenyl-2-Naphthylamine 2/50 1/50 3/50 Rotenone 0150 1/50 1/50 I-Ascorbic Acid 0149 0149 ...

  17. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... Evidence P Clear Evidence P Clear Evidence P Clear Evidence TR-320 08/19/86 Rotenone 83-79-4 EE Equivocal Evidence NE No Evidence NE No Evidence NE No Evidence TR-319 03/26/86 ...

  18. GMM-03: Genetically Modified Model Report on Trimethylolpropane... 7.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm03_508.pdf

    ... in a Tg.AC mouse treated with 166 mg/kg rotenone in the 24-week skin application study. ... However, in an NTP dermal carcinogenicity study on rotenone in Tg.AC mice, no skin ...

  19. Draft RoC Monograph Cobalt Appendix: RoC Peer Review; July 22... 1.7MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_draftmonograph_appen.pdf

    ... Confounding + Animals and bedding periodically dusted with rotenone powder; not clear if ... Animal bedding was periodically dusted with rotenone powder and half of the exposed group ...

  20. Revised Draft RoC Monograph Cobalt Appendix: RoC Peer Review... 1.7MB

    https://ntp.niehs.nih.gov/ntp/roc/draftmono/revised_cobalt_append.pdf

    ... Confounding + Animals and bedding periodically dusted with rotenone powder; not clear if ... Animal bedding was periodically dusted with rotenone powder and half of the exposed group ...

  21. GMM-04: Genetically Modified Model Report on Pentaerythritol... 5.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm04_508.pdf

    ... However, in NTP dermal car- cinogenicity studies on rotenone in Tg.AC mice, no papillomas ... previously reported in only one other Tg.AC mouse study of rotenone (Mahler et al., 1998). ...

  22. TR-349: Two Pentachlorophenol Technical-Grade Mixtures (CASRN... 30.4MB

    https://ntp.niehs.nih.gov/go/tr349

    ... 4/50 C.I. Solvent Yellow 14 5/49 10/49 Rotenone 7/47 6/47 L-Ascorbic ac1d 6/50 10/50 ... 3 D&CRedNo.9 C.I. Solvent Yell ow 14 Rotenone L.Ascorbic acid TOTAL SD(bl Range(c) ...

  23. RoC Monograph: Cobalt and Cobalt Compounds; April 2016 3.5MB

    https://ntp.niehs.nih.gov/ntp/roc/monographs/cobalt_final_508.pdf

    ... Animal bedding was periodically dusted with rotenone powder. Other comments: Results were ... Bedding was periodically dusted with rotenone powder. Incomplete reporting for many ...

  24. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... Report TR-320 PDF (11.5 MB) Toxicology and Carcinogenesis Studies of Rotenone (CASRN 83-79-4) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1988 Technical Report TR-319 ...

  25. Background: Dimethylethanolamine (DMAE) [108-01-0] and Selected... 1.3MB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/dmae_update_110002_508.pdf

    ... 27 nmol/minute per mg, p<0.025), rotenone-insensitive NADH-dependent cytochrome-c reductase (276 ± 24 nmol/minute per mg, p<0.025), and rotenone-sensitive NADH-dependent ...

  26. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... Report TR-320 PDF (11.5 MB) Toxicology and Carcinogenesis Studies of Rotenone (CASRN 83-79-4) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1988 Technical Report TR-319 ...

  27. Guidance Document on Using In Vitro Data to Estimate In Vivo... 6.5MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/guidance0801/iv_guide.pdf

    ... 36.0 8 Digitoxin 0.00011 0.073 55.8 134 Rotenone 0.00013 0.33 130.2 9 Amethopterin ... 124.9 23 Daraprim 0.0089 0.51 126.9 134 Rotenone 0.00013 0.33 130.2 9 Amethopterin ...

  28. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... Carcinogenicity TR-320 PDF (11.5 MB) Toxicology and Carcinogenesis Studies of Rotenone (CASRN 83-79-4) in F344/N Rats and B6C3F1 Mice (Feed Studies) 1988 Long-Term Carcinogenicity ...

  29. TR-393: Sodium Fluoride (CASRN 7681-49-4)in F344/N Rats and B6C3F1Mice... 21.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr393.pdf

    ... N-phenyl-2-naphthylamine Rotenone 1-ascorbic acid f4-Dichlomphend Diphenylhydantoin ... 1/49 N-phenyl-&naphthylamine 1/49 Rotenone 0/50 I-arcorbi acid 0149 ...

  30. ICCVAM Biennial Progress Report 2012-2013 3.0MB

    https://ntp.niehs.nih.gov/iccvam/docs/annrpt/iccvam-bienrpt-2014-508.pdf

    ... The initial focus is on two registered fish toxicants, rotenone and antimycin-A, but the 35 ICCVAM Biennial Progress Report 2012-2013 35 ICCVAM Agency Activities 2012-2013 ICCVAM ...

  31. Report: International Workshop on In Vitro Methods for Assessing... 25.4MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/finalrpt/finalall0801.pdf

    ... 507.68 0.071 8 Digitoxin 71-63-6 0.08 0.00011 55.8 0.073 NA NA 765.05 0.073 134 Rotenone 83-79-4 0.05 0.00013 130.2 0.33 351.1 0.89 394.45 0.33 9 Amethopterin 59-05-2 0.06 0.00014 ...

  32. Minutes: BSC; March 27, 1984 3.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1984/march/bsc_minutes19840327_508.pdf

    ... A chronic study on rotenone was analyzed to determine effects produced by long-term exposure . Data from large NCTR experiments were analyzed in order to study experimental ...

  33. GMM-09: Genetically Modified Model Report on Dicyclohexylcarbodiimide... 1.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm09_508.pdf

    ... However, co-occurrence of these lesions is not always the case. For example, in the NTP dermal carcinogenicity studies on rotenone in Tg.AC hemizygous mice (Eastin et al., 1998), ...

  34. TR-338: Erythromycin Stearate (CASRN 643-22-1) in F344/N Rats... 10.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr338.pdf

    ... weeks (b)Squamous cell carcinoma ofthe tongue observed in the rotenone study TABLE B4b. ... 247 L-Ascorbic Acid 320 Rotenone 248 4,4'-Methylenedianiline ...

  35. TOX-79: Genistein (CASRN 446-72-0) 2.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox079.pdf

    ... Metab. 84, 4017-4024. Harvey, J.S., Howe, J.R., Lynch, A.M., and Rees, R.W. (2005). The results of five coded compounds: Genistein, metaproterenol, rotenone, p-anisidine and ...

  36. ICCVAM Background Review Document (Vol 2): In Vitro Cytotoxicity... 61.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/brd_tmer/brdvol2_nov2006.pdf

    ... bromoxynil (phenol), fipronil, carbaryl, rotenone, metaldehyde, molinate, ... TESS, NTP DEA Pharmaceutical (stimulant) Rotenone 60 RC, TESS, EPA, NTP Pesticide ...

  37. Draft RoC Monograph Cobalt: RoC Peer Review; July 22, 2015 2.8MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_draftmonograph.pdf

    ... Animal bedding was periodically dusted with rotenone powder. Other comments: Results were ... Bedding was periodically dusted with rotenone powder. Incomplete reporting for many ...

  38. Revised Draft RoC Monograph Cobalt: RoC Peer Review; July 22... 3.0MB

    https://ntp.niehs.nih.gov/ntp/roc/draftmono/revised_cobalt.pdf

    ... Animal bedding was periodically dusted with rotenone powder. Other comments: Results were ... Bedding was periodically dusted with rotenone powder. Incomplete reporting for many ...

  39. GMM-11: Genetically Modified Model Report on Dichloroacetic Acid... 1.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm11_508.pdf

    ... The severity of the hyper- keratosis and hyperplasia was generally minimal to mild. In a previous NTP study, rotenone applied to the skin caused hyperplasia, hyperkeratosis, and ...

  40. TR-545: Genistein (CASRN 446-72-0) in Sprague-Dawley Rats (feed... 11.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr545.pdf

    ... Metab. 84, 4017-4024. Harvey, J.S., Howe, J.R., Lynch, A.M., and Rees, R.W. (2005). The results of five coded compounds: Genistein, metaproterenol, rotenone, p-anisidine and ...

  41. CERHR Monograph: Potential Human Reproductive and Developmental... 6.3MB

    https://ntp.niehs.nih.gov/ntp/ohat/bisphenol/bisphenol.pdf

    ... Mechanistic.investigations.of.low.dose.ex- posures.to.the.genotoxic.compounds.bis- phenol-A.and.rotenone..651:56.-.63. 244..George.O,.Bryant.BK,.Chinnasamy.R,.Co- ...

  42. TR-417: p-Nitrophenol (CASRN 100-02-7) in Swiss Webster Mice... 7.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr417.pdf

    ... 317 Chlorpheniramine Maleate 318 Ampicillin Trihydrate 319 1,4-Dichlorobenzene 320 Rotenone 321 Bromodichloromethane 322 Phenylephrine Hydrochloride 323 Dimethyl ...

  43. TR-444: Initiation/Promotion Study of o-Benzyl-p-Chlorophenol... 6.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr444.pdf

    ... 317 Chlorpheniramine Maleate 318 Ampicillin Trihydrate 319 1,4-Dichlorobenzene 320 Rotenone 321 Bromodichloromethane 322 Phenylephrine Hydrochloride 323 Dimethyl ...

  44. TR-389: Sodium Azide (CASRN 26628-22-8) in F344 Rats (Gavage... 8.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr389.pdf

    ... 317 Chlorpheniramine Maleate 318 Ampicillin Trihydrate 319 1,4-Dichlorobenzene 320 Rotenone 321 Bromodichloromethane 322 Phenylephrine Hydrochloride 323 Dimethyl ...

  45. TR-409: Quercetin (CASRN 117-39-5) in F344 Rats (Feed Studies... 9.6MB

    https://ntp.niehs.nih.gov/go/tr409

    ... Chlorpheniramine Maleate Ampicillin Trihydrate 1,4-Dichlorobenzene Rotenone Bromodichloromethane Phenylephrine Hydrochloride Dimethyl Methylphosphonate Boric ...

  46. TR-410: Naphthalene (CASRN 91-20-3) in B6C3F1Mice (Inhalation... 8.6MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr410.pdf

    ... Chlorpheniramine Maleate Ampicillin Trihydrate 1,4-Dichlorobenzene Rotenone Bromodichloromethane Phenylephrine Hydrochloride Dimethyl Methylphosphonate Boric ...

  47. TR-278: 2,6-Xylidine (2,6-Dimethylaniline) (CASRN 87-62-7) in... 9.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr278.pdf

    ... Chlorpheniramine Maleate Ampicillin Trihydrate 1,4-DichIorobenzene Rotenone Bromodichloromethane Phenylephrine Hydrochloride Dimethyl Methylphosphonate Boric Acid ...

  48. TR-335: C.I. Acid Orange 3 (CASRN 6373-74-6) in F344/N Rats and... 12.4MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr335.pdf

    ... Ampicillin Trihydrate 245 Melamine 319 1,4-Dichlorobenzene 247 L-Ascorbic Acid 320 Rotenone 248 4,4' -Methylenediani!ine Dihydrochloride 321 Bromodichloromethane 249 Amosite ...

  49. TR-353: 2,4-Dichlorophenol (CASRN 120-83-2) in F344/N Rats and... 10.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr353.pdf

    ... 0143 C.I. Disperse Yellow 3 0/50 D & C Red No. 9 0147 C.I. Solvent Yellow 14 0147 Rotenone (b, 1/45 I-Ascorbic acid 0150 TOTAL 1/329 (0.3%) SD (c) 0.84% Range (d) High 1/45 Low ...

  50. TR-359: 8-Methoxypsoralen (CASRN 298-81-7) in F344/N Rats (Gavage... 7.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr359.pdf

    ... 317 Chlorpheniramine Maleate 318 Ampicillin Trihydrate 319 1,4-Dichlorobenzene 320 Rotenone 321 Bromodichloromethane 322 Phenylephrine Hydrochloride 323 Dimethyl ...

 
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