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RoC Profile: 2-Acetylaminofluorene; 15th RoC 2021 124KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/acetylaminofluorene.pdf
Dietary administration of 2-acetylamino fluorene caused cancer of the liver ... In hamsters of both sexes, intratracheal instillation of 2-acetylamino fluorene caused ...
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RoC Profile: Norethisterone; 15th RoC 2021 125KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/norethisterone.pdf
Studies on Mechanisms of Carcinogenesis In female rats orally exposed first to the carcinogen N-2-acetylamino- fluorene at a non-tumorigenic dose and then to norethisterone, be- ...
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Poster: Use of Survey Sampling to Develop an Evidence Map of... 1.7MB
https://ntp.niehs.nih.gov/ntp/results/pubs/posters/wang_gems_20221101.pdf
... 0) 0 (0 - 0) 0 (0 - 0) - - - 11H-Benzo[a]fluorene 1 (1 - 1) 1 (1 - 1) 0 (0 - 0) 0 (0 - 0) ... Benzo[c]fluorene 7 (7 - 7) 3 (3 - 3) 0 (0 - 0) 0 (0 - 0) 0 (0 - 0) 0 (0 - 0) 0 (0 - 0) 0 ...
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Poster: An Evaluation of The Performance of Survey Sampling in... 953KB
https://ntp.niehs.nih.gov/sites/default/files/2024-03/Wang_SOT20240310.pdf
... 1000 2000 3000 4000 Pyrene Phenanthrene Fluorene Fluoranthene Dibenzo[a,l]pyrene ... 305 248 57 Benz[a]anthracene 941 357 584 Fluorene 496 65 431 Sheet3 (2) Benz[a]anthracene ...
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RoC Background Document: Diesel Exhaust Particulates; Dec. 2... 5.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/dieselexhaust_508.pdf
... Compound Molecular Weight CAS number Concentration (ng/mg extract) Acenaphthalene 152 208-96-8 30 Trimethylnaphthalene 170 28652-77-9 140-200 Fluorene 166 86-73-7 100-168 ...
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TOX-13: Trinitrofluorenone (CASRN 129-79-3) 2.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox013.pdf
... (TNF) is a trinitro-derivative of fluorene that was used extensively as a toning ... is well established that various nitro and amine derivatives of fluorene are carcinogenic. ...
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Polycyclic Aromatic Compounds 83KB
https://ntp.niehs.nih.gov/whatwestudy/topics/pacs
... 82-86-0 Ongoing Pyrene 129-00-0 Ongoing Dibenzo[a,l]pyrene 191-30-0 Ongoing Benzo[c]fluorene 205-12-9 Ongoing Chrysene 218-01-9 Ongoing Benzo[k]fluoranthene 207-08-9 Ongoing ...
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Protocol: Systematic Review of Inflammation-based Atherosclerosis... 1001KB
https://ntp.niehs.nih.gov/sites/default/files/2023-07/protocol_atherosclerosisjuly2023_508.pdf
... OR 'Anthanthrene':ti,ab OR "Benzo[c]fluorene":ti,ab OR "Dibenzo[a,e]fluoranthene":ti,... OR 'Nitrochrysene':ti,ab OR "Benzo(j,k)fluorene":ti,ab OR "1-Nitropyrene":ti,ab OR ...
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RR-11: The Chemical and Physical Characterization of Recycled... 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr11_508.pdf
... - 2.00 0.214 - 2.72 279 - 2.73 31.9 Fluorene 0.00158 0.0608 ND 0.00114 0.0602 ND ND ... - 6.46 I ND - 19.9 I NDI - 17.7 I NDI Fluorene ND ND ND ND ND ND ND ND 0.491 ND ND ...
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TR-062: Endosulfan (CASRN 115-29-7) 3.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr062.pdf
... clonitralid (1420-04-8); nitrofen (1836-75-5); chlorobenzilate (510-15-6); mexacarbate (315-18-4); amitrole (61-82-5); acetylamino- fluorene (53-96-3); and safrole (94-59-7). ...
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TR-147: Mexacarbate (CASRN 315-18-4) 3.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr147.pdf
... endosulfan (115-29-7); trifluralin (1582-0908); amitrole (61-82-5); acetylamino- fluorene (53-96-3); safrole (94-59-7); and sulfallate (95-06-7). * CAS registry numbers are ...
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TR-085: 4-Chloro-m-phenylenediamine (CASRN 5131-60-2) 3.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr085.pdf
... rats were housed * in a room with other rats receiving diets containing acetylamino- fLuorene (53-96-3); p-cresidine (120-71-8); 2,3,5,6-tetrachloro-4- nitroanisole (2438-88-2); ...
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TR-125: Dioxathion (CASRN 78-34-2) 1.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr125.pdf
... (82-68-8); clonitralid (1420-04-8); nitrofen (1836-75-5); endosulfan (115-29-7); mexacarbate (315-18-4); amitrole (61-82-5); safrole (94-59-7); and acetylamino- fluorene (53-96-3). ...
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TR-064: 1-Nitronaphthalene (CASRN 86-57-7) 3.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr064.pdf
... High dose control mice were in a room in which other mice were receiving diets treated with 2-methyl-l-nitroanthraquinone (129-15-7); acetylamino- fluorene (53-96-3); p-cresidine ...
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TR-101: Formulated Fenaminosulf (CASRN 140-56-7) 3.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr101.pdf
... mice receiving diets containing 2-methyl-l-nitroanthraquinone (129-15-7); acetylamino- fluorene (53-96-3); p-cresidine (120-71-8); and 4-chloro-m-phenylene- diamine (5131-60-2). ...
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ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential... 10.6MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edfinalrpt0503/edfinrpt.pdf
... 6 Androstene 2 Flavone 4 Anilide 3 Fluorene 1 Anthracene 1 Glutaramide 1 Aromatic ... Polycyclic aromatic hydrocarbon; Fluorene None Fluoxymestrone 76-43-7 Steroid, ...
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TR-000: Technical Grade Chlordecone (Kepone) (CASRN 143-50-0... 994KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/trchlordecone(kepone).pdf
... Cancer Inst., 44: 419-423, 1970. 8. Symeonidis, A.: Tumors Induced by 2-Acetyl amino-fluorene in Virgin and Breeding Females of Five Strains of Rats and in their Offspring. J. ...
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RoC Background Document: Tobacco Smoking; Dec. 2-3, 1998 3.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/environmentalts_noapps_508.pdf
... 4.40 4.80 0.15 9.20 16.00 mg/m 3 µg/m 3 µg/m 3 µg/cm 3 µg/m 3 Benzo[a]fluorene Benzo[a]fluorene IA IA 39.00 Qual (ng/m 3 ) ng/m 3 Benzo[a]fluorene MS 184.00 ng/cig ...
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TR-036: Anthranilic Acid (CASRN 118-92-3) 2.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr036.pdf
... Methuen & Co. , Ltd., London, 1970, pp. 48-52. Dunning, W. F., Curtis, M. R., and Maun, M. E. , The effect of added dietary tryptophan on the occurrence of 2-acetylamino- fluorene-...
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TR-071: L-Tryptophan (CASRN 73-22-3) 2.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr071.pdf
... Dunning, W. F., Curtis, M. R. , and Maun, M. E. , The effect of added dietary tryptophane on the occurrence of 2-acetylamino- fluorene-induced liver and bladder cancer in rats. ...
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XDS Submission of the LUMI-CELL ER Test Method 3.2MB
https://ntp.niehs.nih.gov/iccvam/methods/endocrine/endodocs/iccvamsubmission28jan05.pdf
... - 1.95E+04 1.00E+02 - 4.88E-02 2.63E-04 - 1.28E-07 > 95% Chem Service liquid Fluorene 86-73-7 Natural Product environmental contaminant 4.00E+07 - 1.95E+04 1.00E+02 - 4.88E-02 ...
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Submission of XDS's LUMI-CELL ER High-Throughput System for Screening... 2.4MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/erta-tmer/appxc/annexa/xds-sub.pdf
... - 1.95E+04 1.00E+02 - 4.88E-02 2.63E-04 - 1.28E-07 > 95% Chem Service liquid Fluorene 86-73-7 Natural Product environmental contaminant 4.00E+07 - 1.95E+04 1.00E+02 - 4.88E-02 ...
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Comment: Meat-related exposures; Robert Turesky, University of... 4.6MB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/turesky20161005.pdf
... years of research on N-acetyl-2-amino- fluorene, one of the most versatile compounds in ... form of the carcinogen N-acetyl-2-amino- fluorene to rat liver DNA in vivo. Chem.-Biol. ...
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TOX-34: 1-Nitropyrene (CASRN 5522-43-0) 1.1MB
https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox034.pdf
... Belges 74, pp. 418-425. MATSUOKA, A., SOFUNI, T., MIYATA, N., AND ISHIDATE, M., JR. (1991). Clastogenicity of 1-nitropyrene, dinitropyrenes, fluorene and mononitrofluorenes in ...
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TOX-17: Black Newsprint Inks 2.1MB
https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox017.pdf
... 1, 2-Dimethylnaphthalene " ~5 3 0.8 Acenaphthylene " ND c 2 2 Acenaphthene " " 2 1 Fluorene " 12 4 3 Phenanthrene " 21 16 4 Anthracene " ND c 1 0.2 2-Methylphenanthrene " 14 13 ...
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Independent Peer Review Evaluation of the Murine Local Lymph... 13.1MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna/llnarep.pdf
... et al. (1995) 2-(N- Acetoxyacetamido)fluorene// 2- AAAF amide// PAH// ?acetylated ... al. (1995) 2-Nitrofluorene// 2-Nitro-9H- fluorene 607-57-8 nitroaromatic// PAH - Ashby et ...
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TR-476: Primidone (CASRN 125-33-7) in F344/N Rats and B6C3F1Mice... 13.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr476.pdf
... Effects of varying the dietary concentration of phenobarbital on its enhancemant of 2-acetylamino- fluorene-induced hepatic tumorigenesis. Cancer Res. 40, 3268-3273. Physicians' ...
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TR-494: Anthraquinone (CASRN 84-65-1) in F344/N Rats and B6C3F1Mice... 10.7MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr494.pdf
... and not mutagenic in the presence of S9. 9-Nitroanthracene induced 53 revertants/µg in TA98 without S9 while the positive control, 2-nitro- fluorene, induced 370 revertants/µg. ...
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TR-044 In Vitro Carcinogenesis: Guide to the Literature, Recent... 18.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr044.pdf
... Z. Krebsforsch, 81 (1974), 75-78. 4. Brusick, D., and H. Andrews. "Comparison of the Genetic Activity of Dimethylnitrosamine, Ethyl Methanesulphonate, 2-acetylamino- fluorene and ...
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Peer Review Evaluation Report: Oral Up-and-down Procedure (NIH... 2.1MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/udpproc/udpfin01/vol_2.pdf
... amide. 721.3740 Bisalkylated fatty alkyl amine oxide 721.3760 Fluorene-containing diaromatic amines. 721.3764 Fluorene substituted aromatic amine. 721.3790 Polyfluorocarboxylates. ...