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Risk Assessment of Exposure to Triazole Fungicides by Human Biomonitor... 1.3MB
https://ntp.niehs.nih.gov/sites/default/files/2024-03/SOT2024-Marciano-poster.pdf
Acknowledgments Risk Assessment of Exposure to Triazole Fungicides by Human Biomonitoring ... scenario marked by the highest urinary triazole values, indicative of more intense ...
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RoC Profile: Amitrole; 15th RoC 2021 127KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/amitrole.pdf
Properties Amitrole is a triazole compound that is a colorless to white crystalline solid ... Hirose M, Hirao K. 1976. Tumorigenic effect of 3-amino-1H-1,2,4- triazole on rat thyroid. ...
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TR-088: 1H-Benzotriazole (CASRN 95-14-7) 3.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr088.pdf
... in Rats IH-Benzo- Sex and Initial triazole Test No. of in Diet b Group Animals 3 ... m - Rpm^n- JJ\ZlL£i\J Sex and Initial triazole Time on Study Time-Weighted Test No. of ...
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TR-081: Trimethylphosphate (CASRN 512-56-1) 3.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr081.pdf
... Animals administered trimethylphosphate were housed in the same room as animals of the same species administered the following chemicals: RATS Feed Studies l-H-l,2,4-triazole-3-ami...
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SACATM 2020: Public Comments from HSUS/HSLF 467KB
https://ntp.niehs.nih.gov/ntp/about_ntp/sacatm/2020/september/publiccomm/katrinak20200820_sacatm_508.pdf
.../rapid-chemical-exposure-and-dose-research 15 Friedman et al. 2016. A predictive data-driven framework for endocrine prioritization: a triazole fungicide case study. ...
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Poster Abstracts: In Vitro to In Vivo Extrapolation for High... 132KB
https://ntp.niehs.nih.gov/iccvam/meetings/ivive-wksp-2016/posterabstracts-all-508.pdf
... Framework for Endocrine Prioritization: Triazole Fungicide Case Study K Paul Friedman 1 , ... Evaluation of relevant data for three triazole fungicides, triadimefon, propiconazole, and ...
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ICCVAM Test Method Evaluation Report on the Applicability Domain... 16.1MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ad/tmer-revmay2012.pdf
... Neg CBA BALBc 3-Amino-5- mercapto- 1,2,4-triazole DMSO 2 1 1 0 1 1 0 11.6 5.2 Benzocaine ... Two substances, 3-Amino-5-mercapto-1,2,4-triazole and 2,4- dinitrofluorobenzene, had ...
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ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential... 10.6MB
https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edfinalrpt0503/edfinrpt.pdf
... 1 Pyrimidine 3 Triazine 1 Quinoline 1 Triazole 1 Resorcylic acid lactone 1 ... Anastrazole 120511-73-1 Nitrile; Triazole Pharmaceutical 4-Androstenedione 63-05-8 ...
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TR-093: 3-Amino-9-ethylcarbazole Hydrochloride (CASRN 132-32... 6.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr093.pdf
... in feed: (CAS 61-82-5) 3-amino-s-triazole (positive control) (CAS 129-15-7) ... in feed: (CAS 61-82-5) 3-amino-s-triazole (positive control) (CAS 138-89-6) ...
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ICCVAM Evaluation of In Vitro Test Methods for Assessing Dermal... 3.1MB
https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/cwgfinal02/cwgfinal.pdf
... amine ORGBA NC NC NC NC 59 4-Amino-1,2,4-triazole ORGBA NC NC NC NC 8 Isopropanol NORG NC ... amine ORGBA NC NC NC NC 59 4-Amino-1,2,4-triazole ORGBA NC NC NC NC 8 Isopropanol NORG NC ...
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Background Review Document: In Vitro Test Methods for Assessing... 2.4MB
https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/epis_brd0801.pdf
... amine ORGBA NC NC NC NC 59 4-Amino-1,2,4-triazole ORGBA NC NC NC NC 8 Isopropanol NORG NC ... amine ORGBA NC NC NC NC 59 4-Amino-1,2,4-triazole ORGBA NC NC NC NC 8 Isopropanol NORG NC ...
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RR-05: National Toxicology Program Approach to Genomic Dose-Response... 574KB
https://ntp.niehs.nih.gov/ntp/results/pubs/rr/reports/rr05_508.pdf
... Toxicological Sciences. 2017; 158(1):199-212. http://dx.doi.org/10.1093/toxsci/kfx085 9. Robinson JF, Tonk ECM, Verhoef A, Piersma AH Triazole induced concentration-related gene ...
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Minutes: BSC; Feb. 5, 1998 713KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1998/february/19980205bscmins_508.pdf
... Chemicals Deferred for Additional Information are: (1) 3-Amino-5-mercapto-1,2,4-triazole ... Chemical Nomin. by Testing for Information needed 5-Amino-5-mercapto-1,2,4-triazole ...
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ICCVAM Report: Corrositex: An In Vitro Method for Assessing Dermal... 5.1MB
https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/corprrep.pdf
... NP 1996 Submission alkylphosphoric acid 4M - NP 1996 Submission 4-amino-1,2,4-triazole - ... therefore, not included (4-amino-1,2,4-triazole; butylbenzene; 4-(methylthio)benzaldehyd...
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Performance Standards for In Vitro Test Methods for Skin Corrosion 6.3MB
https://ntp.niehs.nih.gov/iccvam/docs/dermal_docs/ps/ps044510.pdf
... neutral organic NC 4.5 4-Amino-1,2,4-triazole 584-13-4 organic base NC 5.5 ... neutral organic NC 4.5 4-Amino-1,2,4-triazole 584-13-4 organic base NC 5.5 ...
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Nomination Background: 1,3-Dichloro-2-propanol (CASRN: 96-23... 1.5MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/dichloropropanol_508.pdf
... Pretreatment of cultures with 1-aminobenzo- triazole (a cytochrome P450 inhibitor) prevented the toxicity of 1,3-DCP, while pretreatment with diethyl maleate or buthionine ...
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TR-412: 4,4'-Diamino-2,2'-Stilbenedisulfonic Acid Disodium Salt... 11.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr412.pdf
... toxic and carcinogenic effects: sodium 2-(4-styryl-3- sulfophenyl)-2H-naphtho[1,2-d]triazole; disodium 4,4'-bis[(4-anilino-6-morpholino-1,3,5-triazin- 2-yl)amino]stilbene-2,2'-di...
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Peer Review Evaluation Report: Oral Up-and-down Procedure (NIH... 2.1MB
https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/udpproc/udpfin01/vol_2.pdf
... 9.30 3. Flusilazole (97%) Fluorophenyl triazole silane Fungicide 1110.00 674.00 4. ... methylsilyl] methyl]-1H-1,2,4-triazole CAS No. 85509-19-9 Common Name: ...
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CERHR Monograph: Potential Human Reproductive and Developmental... 4.8MB
https://ntp.niehs.nih.gov/ntp/ohat/acrylamide/acrylamide_monograph.pdf
... source not indicated Mouse, (102/E1 × C3H/E1)F 1 males and females Exp 1 Exp2 ABT = 3 × 50 mg/kg 1-aminobenzo- triazole to inhibit metabolism to glycidamide 125 mg/kg i.p. ...
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OECD Guidance Document 34: Validation and International Acceptance... 1.0MB
https://ntp.niehs.nih.gov/iccvam/suppdocs/feddocs/oecd/oecd-gd34.pdf
... Corrosive Octanoic acid (caprylic acid) CAS-No. 124-07-02 Corrosive 4-Amino-1,2,4-triazole CAS-No. 584-13-4 Not corrosive Eugenol CAS-No. 97-53-0 Not corrosive Phenethyl ...
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CERHR Monograph: Potential Human Reproductive and Developmental... 1.4MB
https://ntp.niehs.nih.gov/ntp/ohat/egpg/propylene/pg_monograph.pdf
... examined on day 19. Teratogens tested were: bidrin, 6-aminonicotinamide, 3-acetylpyridine, sulfanilamide, 3-amino-1,2,4 triazole, physostigmine sulfate, and nicotine sulfate. ...
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ICCVAM Test Method Evaluation Report on the Reduced LLNA 21.6MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ld/tmer.pdf
... chemicals GSK Ethyl 1h-1,2,4-triazole-3- carboxylate - 64922-04-9 141.13 -0.02 ... Submitted by M.J. Olson Ethyl 1h-1,2,4- triazole-3- carboxylate 64922- 04-9 DMF - - NC ...
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ICCVAM Test Method Evaluation Report: In Vitro Ocular Toxicity... 5.9MB
https://ntp.niehs.nih.gov/iccvam/docs/ocutox_docs/oteval/otevalrpt.pdf
... Category 1 4 1,2,4-Triazole, sodium salt 41253-21-8 ECETOC Elf Atochem, Inc. Sigma-Aldrich ... data not located Category 1 4 1,2,4-Triazole, sodium salt - - - - - Category I R41 ...
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Usefulness and Limitations of the LLNA for Potency Categorization... 25.3MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-pot/tmer.pdf
... Quinoxyfen/ cyproconazole 6 5,7-dichloro-4-(4- fluorophenoxy)quino- line/1H-1,2,4-Triazole- 1-ethanol, alpha-(4- chlorophenyl)-alpha- (1-cyclopropylethyl)- 124495-18-7/ ...
