-
Appendices for NTP Monograph on Developmental Effects and Pregnancy... 11.1MB
https://ntp.niehs.nih.gov/ntp/ohat/cancer_chemo_preg/cancerchemo_appendfinal_508.pdf
... 3 NA NA Trofosfamide NA NA NA Vinblastine 3 NA D Vincristine 3 NA D Vindesine NA ... OR velcade OR vepesid OR vesanoid OR vinblastine OR vincasar OR vincrex OR vincristine ...
-
NTP Monograph: Developmental Effects and Pregnancy Outcomes Associated... 23.8MB
https://ntp.niehs.nih.gov/ntp/ohat/cancer_chemo_preg/chemopregnancy_monofinal_508.pdf
......... 155 5.32 Vinblastine ......Table 75: Pharmacology of vinblastine in adult humans ......
-
RoC Profile: Dacarbazine; 15th RoC 2021 122KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/dacarbazine.pdf
subpopulation of patients treated with dacarbazine plus adriamycin, bleomycin, and vinblastine (ABVD therapy) alone or in combination with radiother- apy; however, the number of ...
-
Testis, Germ Cell - Exfoliation - Nonneoplastic Lesion Atlas 287KB
https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-male/testis/GermCell-Exfoliation
Russell LD, Malone JP, MacCurdy DS. 1981. Effect of the microtubule disrupting agents, colchicine and vinblastine, on seminiferous tubule structure in the rat. Tissue Cell ...
-
Testis, Germ Cell - Exfoliation 687KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/male_reproductive/testis/gcexfol/testis_germ_cell-exfoliation_508.pdf
... JP, MacCurdy DS. 1981. Effect of the microtubule disrupting agents, colchicine and vinblastine, on seminiferous tubule structure in the rat. Tissue Cell 13:349-367. Abstract: ...
-
RoC Profile: Azacitidine; 15th RoC 2021 129KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/azacitidine.pdf
... Azacitidine is also used in clinical trials in combina- tion with other antineoplastic agents, such as vincristine, prednisone, vinblastine, cytarabine, or amsacrine (IARC 1990). ...
-
RoC Background Document: Azacitidine; Nov. 18-19, 1996 3.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/azacitidine1_508.pdf
... It is used 4 NTP Report on Carcinogens 1996 Background Document for Azacitidine alone or in combination with vincristine, vinblastine, prednisone, cytarabine, or amsacrine, at a ...
-
OHAT Evaluation: Protocol for a Systematic Review to Evaluate... 1018KB
https://ntp.niehs.nih.gov/ntp/ohat/aheaoecca/protocol201510_508.pdf
... OR vepesid[tiab] OR vesanoid[tiab] OR vinblastine[tiab] OR vincasar[tiab] OR ... OR velcade OR vepesid OR vesanoid OR vinblastine OR vincasar OR vincrex OR vincristine ...
-
OHAT Evaluation: Protocol for a Systematic Review to Evaluate... 1.1MB
https://ntp.niehs.nih.gov/ntp/ohat/aheaoecca/protocol201812_508.pdf
... OR vepesid[tiab] OR vesanoid[tiab] OR vinblastine[tiab] OR vincasar[tiab] OR ... OR velcade OR vepesid OR vesanoid OR vinblastine OR vincasar OR vincrex OR vincristine ...
-
TR-415: Polysorbate 80 (CASRN 9005-65-6) in F344/N Rats and B6C3F1Mice... 12.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr415.pdf
... drugs colcemid, colchicine, and 16 Polysorbate SO, NTP TR 415 vinblastine resulted in increased sensitivity of the cells to the effects o f these drugs (Stavrovskaya et aL, 1975). ...
-
Minutes: MPRP; Oct. 1-2, 2012 559KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2012/october/minutes20121002_508.pdf
... Microtubule Function Inhibitors: Vinblastine First reviewer Dr. Polifka said her only ... patients with Hodgkin's lymphoma of which 6 were treated with single agent vinblastine. ...
-
NTP Monograph: Systematic Review of Occupational Exposure to... 6.2MB
https://ntp.niehs.nih.gov/ntp/ohat/oeccaaho/mgraph/occchemo_final20190300_508.pdf
... OR vepesid[tiab] OR vesanoid[tiab] OR vinblastine[tiab] OR vincasar[tiab] OR Systematic ... OR velcade OR vepesid OR vesanoid OR vinblastine OR vincasar OR vincrex OR vincristine ...
-
TOX-59: Chloral Hydrate (CASRN 302-17-0) 10.8MB
https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox059.pdf
... Res. 198, 145-152. Mailhes, J.B., Aardema, M.J., and Marchetti, F. (1993). Investigation of aneuploidy induction in mouse oocytes following exposure to vinblastine-sulfate, ...
-
TR-503: Chloral Hydrate (Ad Libitum and Dietary Controlled) ... 5.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr503.pdf
... Res. 198, 145-152. Mailhes, J.B., Aardema, M.J., and Marchetti, F. (1993). Investigation of aneuploidy induction in mouse oocytes following exposure to vinblastine-sulfate, ...
-
TR-502: Chloral Hydrate (CASRN 302-17-0) in B6C3F1Mice (Gavage... 8.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr502.pdf
... Res. 198, 145-152. Mailhes, J.B., Aardema, M.J., and Marchetti, F. (1993). Investigation of aneuploidy induction in mouse oocytes following exposure to vinblastine-sulfate, ...
-
CERHR Monograph: Hydroxyurea 3.6MB
https://ntp.niehs.nih.gov/ntp/ohat/hydroxyurea/humonograph20090401.pdf
... II-33 Appendix II 292 LIEBELT ET AL. was discontinued after the diagnosis, and therapy with adriamycin, bleomycin, vinblastine, and dacarbazine was given for the Hodgkin's disease. ...
-
TOX-35: Chemical Mixture of 25 Groundwater Contaminants 11.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox35.pdf
... Bone marrow has less reserve in patients with prior exposure to irradiation and it is thus more sensitive to the myelotoxic effects of subsequent treatment of vinblastine [22] . ...
-
RoC Background Document for Lead and Lead Compounds - May 8,... 3.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/lead-public_508.pdf
... Toxicol Lett 8:165-169. 166. Jagetia, G.C. and P.S. Jacob. 1992. Vinblastine treatment induces dose-dependent increases in the frequency of micronuclei in mouse bone marrow. Mutat ...
