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TR-574: Pyrogallol (CASRN 87-66-1) in F344/N Rats and B6C3F1... 13.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr574_508.pdf
PYROGALLOL (CAS NO. 87-66-1) IN F344/N RATS AND B6C3F1/N MICE (DERMAL STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 February 2013 NTP TR 574 ...
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Abstract for TR-574 72KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr574
Abstract for TR-574 Toxicology and Carcinogenesis Studies of Pyrogallol in F344/N Rats and B6C3F1/N Mice (Dermal Studies) CASRN: 87-66-1 Chemical Formula: C6H6O3 Molecular Weight: ...
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Target Organs and Levels of Evidence for TR-574 59KB
https://ntp.niehs.nih.gov/data/tr/500s/tr574levels
Target Organs and Levels of Evidence for TR-574 Toxicology and Carcinogenesis Studies of Pyrogallol (CASRN 87-66-1) in F344/N Rats and B6C3F1 Mice (Topical Application Studies) ...
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Minutes: TR Panel; Feb. 8-9, 2012 371KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2012/february/minutes20120209_508.pdf
VIII. Draft NTP Technical Report TR-574 on Pyrogallol ......VIII. Draft NTP Technical Report TR-574 on Pyrogallol Study Scientist Dr. Minerva ...
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Historical Controls: Pathology Tables by Skin Application/Ethanol... 208KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/path_miceskin_ethanol2014_508.pdf
Battelle Columbus Laboratory 059903204 09/21/04 729 50(1) 37(698) 56.4 Pyrogallol Female Battelle Columbus Laboratory 059903204 09/20/04 729 50(1) 33(675) 69.3 Pyrogallol NOTE: The ...
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Historical Controls: Pathology Tables by Skin Application/Ethanol... 132KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/miceskinethanol2013_508.pdf
09/21/04 729 50(1) 37(698) 56.4 Pyrogallol Female Southern Research Institute ... 09/20/04 729 50(1) 33(675) 69.3 Pyrogallol NOTE: The text on page 2 ("Report ...
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Historical Controls: Pathology Tables by Skin Application/Ethanol... 109KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/ratsf344skinethanol2013_508.pdf
09/15/04 727 50(1) 23(651) 510.1 Pyrogallol Female Southern Research Institute ... 09/16/04 728 50(1) 29(670) 351.0 Pyrogallol NOTE: The text on page 2 ("Report ...
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Historical Controls: Pathology Tables by Skin Application/Ethanol... 140KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/skinethanolrats2010mar.pdf
09/15/04 727 50(1) 23(651) 510.1 Pyrogallol Female Battelle Columbus Laboratory ... 09/16/04 728 50(1) 29(670) 351.0 Pyrogallol NOTE: The text on page 2 ("Report ...
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Historical Controls: Pathology Tables by Skin Application/Ethanol... 161KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/miceskinethanol.pdf
09/21/04 729 50(1) 37(698) 56.4 Pyrogallol Female Battelle Columbus Laboratory ... 09/20/04 729 50(1) 33(675) 69.3 Pyrogallol NOTE: The text on page 2 ("Report ...
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Historical Controls: Pathology Tables by Skin Application/Ethanol... 157KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/ratsskinethanol.pdf
09/15/04 727 50(1) 23(651) 510.1 Pyrogallol Female Battelle Columbus Laboratory ... 09/16/04 728 50(1) 29(670) 351.0 Pyrogallol NOTE: The text on page 2 ("Report ...
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P08: Statistical Analysis of Primary Tumors for Male & Female... 180KB
https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20523_tables/04_f1_m3_p08.pdf
(DE 71) (GAVAGE CORN OIL) 20009-04 -- beta-Picoline (ORAL WATER) 99032-04 -- Pyrogallol (SKIN ETHANOL) 20320-04 -- Tetrabromobisphenol A (GAVAGE CORN OIL) 88133-08 -- ...
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Historical Controls: Studies on 2014 Reports 20KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/histcont2014_studylist_508.pdf
Skin Acetone Trimethylolpropane triacrylate Mice B6C3F1 Male and Female Skin Ethanol Pyrogallol List of Studies - Wistar Han Rats Species Strain Sex Route Vehicle Chemical Rats ...
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P08: Statisitical Analysis of Primary Tumors for Mice (20209... 159KB
https://ntp.niehs.nih.gov/ntp-db/ntp_reports/ntp_pathology_tbls/20209_tables/04_f1_m3_p08.pdf
(GAVAGE CORN OIL) 20009-04 -- beta-Picoline (ORAL WATER) 99032-04 -- Pyrogallol (SKIN ETHANOL) 20320-04 -- Tetrabromobisphenol A (GAVAGE CORN OIL) 93025-06 -- ...
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Historical Controls: Chemicals by Sex/Species/Route/Vehicle for... 15KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont_2013_by_list_of_studies_508.pdf
B6C3F1 Male and Female Skin Ethanol Pyrogallol List of Studies - F 344/N Rats Species ... F 344/N Male and Female Skin Ethanol Pyrogallol Version: Jun2013 Toxicology Data ...
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Historical Controls: Chemicals by Sex/Species/Route/Vehicle for... 83KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont_2011_studies.pdf
B6C3F1 Male and Female Skin Ethanol Pyrogallol Version: May2011 Toxicology Data ... F 344/N Male and Female Skin Ethanol Pyrogallol Version: May2011 Toxicology Data ...
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TR Panel: Actions; TRs 574, 576, 578, 579, 580, GMM 14, GMM 16... 73KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2012/february/actions_feb2012.pdf
TR-574: Pyrogallol The Panel accepted unanimously (10 yes, 0 no, 0 abstentions) the conclusions as written, no evidence of carcinogenic activity in male or female F344/N rats, ...
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Agenda: TR Peer Review; Feb. 8-9, 2012 91KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/trpanel/2012/february/agenda20120209.pdf
Wyde · Public comment · Peer review comments Panel · Panel discussion Dr. Roberts Draft NTP Technical Report TR-574 on Pyrogallol Study scientists: Dr. Minerva ...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 276KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont2013_mice_allroutes_508.pdf
... 09/21/04 729 50(1) 37(698) 56.4 Pyrogallol Battelle Columbus Laboratory 052032004 ... 09/20/04 729 50(1) 33(675) 69.3 Pyrogallol Battelle Columbus Laboratory 052032004 ...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 189KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont2013_ratsf344_allroutes_508.pdf
... 09/15/04 727 50(1) 23(651) 510.1 Pyrogallol Battelle Columbus Laboratory 059901305 ... 09/16/04 728 50(1) 29(670) 351.0 Pyrogallol Battelle Columbus Laboratory 059901305 ...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 196KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/histcont2014mice_all_routes_508.pdf
... 09/21/04 729 50(1) 37(698) 56.4 Pyrogallol Battelle Columbus Laboratory 052032004 ... 09/20/04 729 50(1) 33(675) 69.3 Pyrogallol Battelle Columbus Laboratory 052032004 ...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 308KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_mice_allroutes.pdf
... 09/21/04 729 50(1) 37(698) 56.4 Pyrogallol Southern Research Institute 052011406 ... 09/20/04 729 50(1) 33(675) 69.3 Pyrogallol Southern Research Institute 052011406 ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... Evidence P Clear Evidence P Clear Evidence P Clear Evidence TR-574 02/08/12 Pyrogallol 87-66-1 NE No Evidence NE No Evidence EE Equivocal Evidence SE Some Evidence TR-573 01/...
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Historical Controls: Pathology Tables for All Routes/Vehicles... 309KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/2010-03-22-hist-ratsallroutes.pdf
... 09/15/04 727 50(1) 23(651) 510.1 Pyrogallol Southern Research Institute 052011407 ... 09/16/04 728 50(1) 29(670) 351.0 Pyrogallol Southern Research Institute 052011407 ...
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Historical Controls: Pathology Tables All Routes/Vehicles for... 309KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_rats_allroutes.pdf
... 09/15/04 727 50(1) 23(651) 510.1 Pyrogallol Southern Research Institute 052011407 ... 09/16/04 728 50(1) 29(670) 351.0 Pyrogallol Southern Research Institute 052011407 ...
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Historical Controls: Chemicals by Sex/Species/Route/Vehicle for... 14KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/histcont_2010_studies.pdf
... Male and Female Skin Ethanol bis(2-Chloroethoxy)methane Rats F 344/N Male and Female Skin Ethanol 1,2-Dibromo-2,4-dicyanobutane Rats F 344/N Male and Female Skin Ethanol Pyrogallol
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National Institute of Environmental Health Sciences: Michelle... 161KB
https://www.niehs.nih.gov/research/atniehs/dtt/assoc/opo/staff/michelle
... ME, Gerken DK, Hejtmancik MR, Hooth MJ. Pyrogallol-associated dermal toxicity and ... ME, Gerken DK, Hejtmancik MR, Hooth MJ. Pyrogallol-associated dermal toxicity and ...
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Technical Reports 903KB
https://ntp.niehs.nih.gov/publications/reports/tr
... Report TR-574 PDF (13.36 MB) Toxicology and Carcinogenesis Studies of Pyrogallol (CASRN 87-66-1) in F344/N Rats and B6C3F1 Mice (Dermal Studies) 2013 Technical Report TR-573 ...
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TR-403: Resorcinol (CASRN 108-46-3) in F344 Rats and B6C3F1Mice... 15.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr403.pdf
... for three metabolites of resorcinol: hydroxyquinol, 3-methoxyphenol, and pyrogallol. ... Pyrogallol was positive, with the most consistent responses recorded in the base ...
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Minutes: BSC; Dec. 9-10, 2009 394KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2009/december/minutes20091210.pdf
... methyl trans- styryl ketone, styrene acrylonitrile trimer, and pyrogallol, would be held in late 2010. Summary Minutes December 9-10, 2009 NTP Board of Scientific Counselors 6 Dr. ...
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Study Reports 1.1MB
https://ntp.niehs.nih.gov/publications/reports
... Report TR-574 PDF (13.36 MB) Toxicology and Carcinogenesis Studies of Pyrogallol (CASRN 87-66-1) in F344/N Rats and B6C3F1 Mice (Dermal Studies) 2013 Technical Report TR-573 ...
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Toxicology/Carcinogenicity 1.1MB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox
... TR-574 PDF (13.36 MB) Toxicology and Carcinogenesis Studies of Pyrogallol (CASRN 87-66-1) in F344/N Rats and B6C3F1 Mice (Dermal Studies) 2013 Long-Term ...
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TR-240: Propyl Gallate (CASRN 121-79-9) in F344/N Rats and B6C3F1Mice... 6.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr240.pdf
... Humans consume con- siderable amounts of gallic acid as a consequence of their consumption of these foods (Singleton and Katzer, 1973). Pyrogallol detected in human urine was ...
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All Past Events 1004KB
https://ntp.niehs.nih.gov/events/past
... Ginkgo Biloba Extract, β-Picoline, Pyrogallol, Trimethylolpropane Triacrylate, ... Ginkgo Biloba Extract, β-Picoline, Pyrogallol, Trimethylolpropane Triacrylate, ...
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TR-513: Decalin (CASRN 91-17-8) in F344/N Rats and B6C3F1Mice... 11.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr513.pdf
... The protein content of each supernatant was measured in a 1:50 dilution in phosphate-buffered saline-Tween using a Pyrogallol Red Assay. Homogenates diluted to 1:50,000 were ...
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TR-515: Propylene Glycol Mono-t-Butyl Ether (CASRN 57018-52-7... 9.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr515.pdf
... The protein content of each supernatant was measured in a 1:50 dilution (in phosphate-buffered saline-Tween) using the Pyrogallol Red Assay. Homogenates diluted to 1:50,000 were ...
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TR-561: Tetralin (CASRN 119-64-2) in F344/N Rats and B6C3F1 Mice... 13.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr561.pdf
... The protein content of each supernatant was measured in a 1:50 dilution in phosphate-buffered saline (PBS)-Tween using the Pyrogallol Red Assay. Analysis of "2u-globulin concen- ...
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TR-494: Anthraquinone (CASRN 84-65-1) in F344/N Rats and B6C3F1Mice... 10.7MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr494.pdf
... Soluble protein content was measured in a 1:50 dilution with phosphate-buffered saline/Tween using a pyrogallol assay. Concentrations of 2u-globulin were measured using a validated ...
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TR-576: Trimethylolpropane Triacrylate (Technical Grade) (CASRN... 6.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr576_508.pdf
... trans-styryl ketone (April 2004) 4/50 Pyrogallol (September 2004) 2/50 ... ketone (April 2004) 23/50 0/50 0/50 Pyrogallol (September 2004) 17/50 1/50 0/50 ...
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RoC References: Antimony and Other Antimony Compounds; Aug. 17... 830KB
https://ntp.niehs.nih.gov/ntp/roc/references/antimonyreferences_508.pdf
... MJ. 2007. Speciation of antimony by adsorptive stripping voltammetry using pyrogallol. ... 2006. Speciation of antimony by adsorptive stripping voltammetry using pyrogallol red. ...
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TR-519: Stoddard Solvent IIC (CASRN 64742-88-7) in F344/N Rats... 8.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr519.pdf
... 4° C, and the supernatant was drawn off and stored at -70° C. The protein content of each supernatant was measured in a 1:50 dilution in PBS-Tween using a pyrogallol red assay. ...
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TR 577: Nondecolorized Whole Leaf Extract of Aloe Barbadensis... 11.3MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr577_508.pdf
... Systems, Sommerville, NJ), with Roche Diagnostic Systems reagents (creatinine, Jaffe method; glucose, Hexokinase method) and Wako reagents (micro protein, pyrogallol red method). ...
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TOX-9: Cresols (CASRNs 95-48-7, 108-39-4, 106-44-5) 6.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox009.pdf
... Set Technol. 18, 953-961. Rogers, KJ M Angel, A., and Butterfield, L. (1968). The penetration of catechol and pyrogallol into mouse brain and the effect on cerebral monoamine ...
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TR-572: Methyl trans-styryl ketone (CASRN 1896-62-4) in F344... 8.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr572_508.pdf
... 2002) 3/50 0/50 3/50 1,2-Dibromo-2,4-dicyanobutane (July 2002) 6/50 0/50 6/50 Pyrogallol (September 2004) 3/50 0/50 3/50 Total (%) 12/150 (8.0%) 0/150 12/150 (8.0%) Mean ± ...
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Historical Controls: Pathology Tables by Route/Vehicle for B6C3F1... 684KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2014/histcont2014mice_byroute_508.pdf
... Battelle Columbus Laboratory 059903204 09/21/04 729 50(1) 37(698) 56.4 Pyrogallol Female Battelle Columbus Laboratory 059903204 09/20/04 729 50(1) 33(675) 69.3 Pyrogallol NOTE: The ...
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Historical Controls: Pathology Tables by Route/Vehicle for Fischer344N... 846KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont2013_ratsf344_by_route_508.pdf
... 09/15/04 727 50(1) 23(651) 510.1 Pyrogallol Female Southern Research Institute ... 09/16/04 728 50(1) 29(670) 351.0 Pyrogallol NOTE: The text on page 2 ("Report ...
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Historical Controls: Pathology Tables by Route/Vehicle for B6C3F1... 1.2MB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_mice_byroute.pdf
... 09/21/04 729 50(1) 37(698) 56.4 Pyrogallol Female Battelle Columbus Laboratory ... 09/20/04 729 50(1) 33(675) 69.3 Pyrogallol NOTE: The text on page 2 ("Report ...
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Historical Controls: Pathology Tables by Route/Vehicle for B6C3F1... 950KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2013/histcont2013_mice_byroute_508.pdf
... 09/21/04 729 50(1) 37(698) 56.4 Pyrogallol Female Southern Research Institute ... 09/20/04 729 50(1) 33(675) 69.3 Pyrogallol NOTE: The text on page 2 ("Report ...
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Historical Controls: Pathology Tables by Route/Vehicle for Fischer... 1.1MB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/2010-03-22-hist-ratsbyroute.pdf
... 09/15/04 727 50(1) 23(651) 510.1 Pyrogallol Female Battelle Columbus Laboratory ... 09/16/04 728 50(1) 29(670) 351.0 Pyrogallol NOTE: The text on page 2 ("Report ...
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Historical Controls: Pathology Tables by Route/Vehicle for Fischer... 1.2MB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_rats_byroute.pdf
... 09/15/04 727 50(1) 23(651) 510.1 Pyrogallol Female Battelle Columbus Laboratory ... 09/16/04 728 50(1) 29(670) 351.0 Pyrogallol NOTE: The text on page 2 ("Report ...