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Nomination Background: Pentachlorophenol, technical (CASRN: 87... 4.6MB
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/pentachlorophenol_508.pdf
... URINARY METABOLITES COOH O H Glucuronic H OH Acid HOH O H HO Cl Cl Cl Cl OH URINE OH H Cl Cl Cl Cl PCP Cl Cl H 2 SO 4 PCP -Glu HOH O SO 3 H Cytochrome P450 Cl Cl Cl Cl Cl PCP - S ...
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RoC Monograph: Pentachlorophenol and By-products of Its Synthesis... 2.9MB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/monographs_final/pentachlorophenol_508.pdf
... United States, ppm ...... 8 Table 1-5. PCP By-products in Different Geographic (United ... Table 2-3. Excretion of PCP in Laboratory Animals ......
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TR-483: Pentachlorophenol (CASRN 87-86-5) in F344/N Rats (Feed... 7.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr483.pdf
PENTACHLOROPHENOL (CAS NO. 87-86-5) IN F344/N RATS (FEED STUDIES) NATIONAL TOXICOLOGY ... STUDIES OF PENTACHLOROPHENOL (CAS NO. 87-86-5) IN F344/N RATS (FEED STUDIES) NATIONAL ...
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TR-349: Two Pentachlorophenol Technical-Grade Mixtures (CASRN... 30.4MB
https://ntp.niehs.nih.gov/go/tr349
TWO PENTACHLOROPHENOL TECHNICAL-GRADE MIXTURES (CAS NO. 87-86-5) IN B6C3FI MICE (FEED ... STUDIES OF TWO PENTACHLOROPHENOL TECHNICAL-GRADE MIXTURES (CAS NO. 87-86-5) IN B6C3Ft MICE ...
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RoC Profile: Pentachlorophenol and By-products of Its Synthesis... 220KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/pentachlorophenol.pdf
Pentachlorophenol and By-products of Its Synthesis CAS No. 87-86-5 (Pentachlorophenol) CAS ... Also known as Dowicide EC-7 (a registered trademark of Dow Chemical Company) or PCP OH Cl ...
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RoC Concept: Pentachlorophenol 299KB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/concepts/pcp_concdocroc8-30-12_508.pdf
NIEHS 1. Rationale Pentachlorophenol (PCP) and its sodium salts are chlorinated ... animals specific for PCP that are adequate for evaluating its potential carcinogenicity. ...
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Draft RoC Monograph for Pentachlorophenol: Literature Search... 2.0MB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/litsearchstrategy/pcpliteraturesearch20130815_508.pdf
used to identify literature for the draft monograph on pentachlorophenol (CASRN 87-86-
5). ... using the synonyms "pentachlorophenol," "87-86-5 (CASRN)," "hydroxypentachlorobenzene," ...
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Protocol: Evaluation of Human Cancer Studies on Exposure to Pentachlor... 363KB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/protocols/pcphumanstudies20130815_508.pdf
Information Pentachlorophenol (CASRN 87-86-5) is a wide spectrum biocide that has been ... Other Sources.) 1 pentachlorophenol , 87-86-5 (CASRN), hydroxypentachlorobenzene, ...
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Abstract for TR-349 66KB
https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr349
CASRN: 87-86-5 Chemical Formula: C6HOCl5 Molecular Weight: 266.3 Synonyms/Common Names: Chlorophen; PCP; penchlorol; penta; pentachlorofenol; pentachlorofenolo; pentachlorphenol; ...
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RoC Review of Pentachlorophenol and By-products of its Synthesis... 72KB
https://ntp.niehs.nih.gov/whatwestudy/assessments/cancer/completed/pcp
its Synthesis (PCP) Power lines against a blue sky Substance Overview Status: RoC: Reasonably anticipated to be a human carcinogen Profile: Pentachlorophenol (PCP) (220.13 KB) ...
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Pentachlorophenol, Dowicide EC-7 10429-G 35KB
https://ntp.niehs.nih.gov/go/ts-10429-g
Pentachlorophenol, Dowicide EC-7 10429-G CASRN: 87-86-5 Formula: C6-H-Cl5-O Synonyms/Common Names PCP Short-Term Toxicity 2 weeks (Dosed-Feed) (C55389) Completed Mice: B6C3F1 26 ...
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Pentachlorophenol, technical 11614-A 37KB
https://ntp.niehs.nih.gov/go/ts-11614-a
technical 11614-A CASRN: 87-86-5 Formula: C6-H-Cl5-O Synonyms/Common Names Phenol, pentachloro- Short-Term Toxicity 4 weeks (Dosed-Feed) (C55378) Completed Mice: B6C3F1 26 weeks ...
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Pentachlorophenol, purified 11616-H 36KB
https://ntp.niehs.nih.gov/go/ts-11616-h
purified 11616-H CASRN: 87-86-5 Formula: C6-H-Cl5-O Short-Term Toxicity 4 weeks (Dosed-Feed) (C54933) Completed Mice: B6C3F1 4 weeks (Dosed-Feed) (C89002) Completed Rats: F344/N ...
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Transgenic LECM (Pentachlorophenol) M960065 33KB
https://ntp.niehs.nih.gov/go/ts-m960065
Pentachlorophenol) M960065 CASRN: 87-86-5 Related: PENTACHLOROPHENOL Formula: C6-H-Cl5-O Synonyms/Common Names Pentachlorophenol (Transgenic LECM) Transgenic-Laboratory of ...
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Nomination Summary for Pentachlorophenol, dowicide EC-7 (N77215... 34KB
https://ntp.niehs.nih.gov/go/nm-n77215
Back to Top CASRN: 87-86-5 Agent Name: Pentachlorophenol, Dowicide EC-7 Testing Status Back to Top CASRN: 87-86-5 Agent Name: Pentachlorophenol, DP-2 Testing Status Back to Top ...
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Pentachlorophenol, DP-2 11615-E 33KB
https://ntp.niehs.nih.gov/go/ts-11615-e
DP-2 11615-E CASRN: 87-86-5 Formula: C6-H-Cl5-O Synonyms/Common Names Phenol, 2,3,4,5,6-pentachloro- Short-Term Toxicity 26 weeks (Dosed-Feed) (C56655) Completed Mice: B6C3F1 Share ...
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Peer Review Report: RoC Peer Review; Dec. 12-13, 2013 287KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2013/december/peerreviewrpt20131213_508.pdf
... NI, Baecher-Steppan L, Schmitz JA. 1982. Immunotoxicity of pentachlorophenol (PCP): increased susceptibility to tumor growth in adult mice fed technical PCP- contaminated diets. ...
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Abstract for TR-483 66KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr483
CASRN: 87-86-5 Chemical Formula: C6HOCl5 Molecular Weight: 266.3 Synonyms/Common Names: Chlorophen; PCP; penchlorol; penta; pentachlorofenol; pentachlorofenolo; ...
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Protocol: Evaluation of Cancer Studies in Experimental Animals... 294KB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/protocols/pcpanimalcancer20130815_508.pdf
Information Pentachlorophenol (CASRN 87-86-5), including its sodium salt (CASRN ... chlorophenol synonyms Pentachlorophenol, 87-86-5 (CASRN), hydroxypentachlorobenzene, ...
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TR 349 Mouse Pathology Tables 571KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr349/path/05074mp04
DOSED FEED Time: 14:43:51 Facility: Battelle Columbus Laboratory Chemical CAS #: 87-86-5 Lock Date: None Cage Range: All Reasons For Removal: All Removal Date Range: All ...
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TR 349 Mouse Pathology Tables 589KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr349/path/05074mp09
DOSED FEED Time: 14:47:10 Facility: Battelle Columbus Laboratory Chemical CAS #: 87-86-5 Lock Date: None Cage Range: All Reasons For Removal: All Removal Date Range: All ...
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TR 349 Mouse Pathology Tables 456KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr349/path/05073mp04
DOSED FEED Time: 13:53:04 Facility: Battelle Columbus Laboratory Chemical CAS #: 87-86-5 Lock Date: None Cage Range: All Reasons For Removal: All Removal Date Range: All ...
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TR 349 Mouse Pathology Tables 456KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr349/path/05073mp09
DOSED FEED Time: 13:53:06 Facility: Battelle Columbus Laboratory Chemical CAS #: 87-86-5 Lock Date: None Cage Range: All Reasons For Removal: All Removal Date Range: All ...
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Nomination Summary for Pentachlorophenol (N20318) 33KB
https://ntp.niehs.nih.gov/go/nm-n20318
The following information relates to the specific agent and may include history from earlier or later nominations for this same agent. Back to Top CASRN: 87-86-5 Agent Name: ...
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Nomination Summary for Pentachlorophenol, technical (N77209) 32KB
https://ntp.niehs.nih.gov/go/nm-n77209
The following information relates to the specific agent and may include history from earlier or later nominations for this same agent. Back to Top CASRN: 87-86-5 Agent Name: ...
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Nomination Summary for Pentachlorophenol, purified (N88312) 32KB
https://ntp.niehs.nih.gov/go/nm-n88312
The following information relates to the specific agent and may include history from earlier or later nominations for this same agent. Back to Top CASRN: 87-86-5 Agent Name: ...
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Minutes: BSC TRRS; Dec. 9, 1997 1.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1997/dec/trrs9dec1997mins_508.pdf
Alcohol Pyridine 1-Chloro-2-propanol, Technical 111-42-2 68603-42-9 120-40-1 93-83-4 87-86-5 115-11-7 78-79-5 98-00-0 110-86-1 127-00-4 Presentations Dermal Dermal Dermal Dermal ...
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TR 349 Mouse Pathology Tables 164KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr349/path/05073mp08
PATHOLOGIST: R. PERSING S. EUSTIS CAS: 87-86-5 ---...PATHOLOGIST: R. PERSING S. EUSTIS CAS: 87-86-5 MICE(B6C3F1) ---...
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Response Peer Review Report: RoC Peer Review; Dec. 12-13, 2013 238KB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2013/december/responsepeerrevrep20131212_508.pdf
... Technical-Grade Mixtures (CAS No. 87-86-5) Administered in B6C3F1 Mice (Feed Studies). ... NTP. 1999. Toxicology and Carcinogenesis Studies of Pentachlorophenol (CAS No. 87-86-5) in ...
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Agenda: Human cancer studies on exposure to pentachlorophenol... 184KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/thirteenth/webinars/2013/draftagendapcp20130411_508.pdf
Public Webinar (via Adobe ® Acrobat ® Connect TM ) Human cancer studies on exposure to pentachlorophenol (PCP): Differentiating potential cancer effects of PCP exposure from ...
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Target Organs and Levels of Evidence for TR-349 59KB
https://ntp.niehs.nih.gov/data/tr/300s/tr349levels
(CASRN 87-86-5) in B6C3F1 Mice (Feed Studies) Chemical (Study Title) CASRN Peer Review Date Route/Exposure Levels Study Laboratory Pentachlorophenol, Dowicide EC-7 87-86-5 04/18/...
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TR 349 Mouse Pathology Tables 158KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr349/path/05074mp08
PATHOLOGIST: R. PERSING S. EUSTIS CAS: 87-86-5 ---...PATHOLOGIST: R. PERSING S. EUSTIS CAS: 87-86-5 MICE(B6C3F1) ---...
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Agenda: Peer Review of Draft RoC Monographs on ortho-Toluidine... 166KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2013/december/agenda20131212_508.pdf
Peer Review of Draft Report on Carcinogens (RoC) Monographs on ortho-Toluidine and Pentachlorophenol and By-products of its Synthesis 1 December 12-13, 2013 Agenda National ...
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TR-349 Pathology Tables and Curves 55KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr349
9 Pathology Tables and Curves TR-349 PENTACHLOROPHENOL PENTACHLOROPHENOL, TECHNICAL Pathology Tables - Mice P03 - Incidence Rates of Non-Neoplastic Lesions By Anatomic Site P04 - ...
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TR 349 Mouse Pathology Tables 108KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr349/path/05073mp03
DOSED FEED Time: 05:28:03 Facility: Battelle Columbus Laboratory Chemical CAS #: 87-86-5 Lock Date: None Cage Range: All Reasons For Removal: All Removal Date Range: All ...
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TR 349 Mouse Pathology Tables 100KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr349/path/05073mp05
DOSED FEED Time: 05:28:16 Facility: Battelle Columbus Laboratory Chemical CAS #: 87-86-5 Lock Date: None Cage Range: All Reasons For Removal: All Removal Date Range: All ...
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TR 349 Mouse Pathology Tables 115KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr349/path/05074mp03
DOSED FEED Time: 06:47:16 Facility: Battelle Columbus Laboratory Chemical CAS #: 87-86-5 Lock Date: None Cage Range: All Reasons For Removal: All Removal Date Range: All ...
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TR 349 Mouse Pathology Tables 94KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr349/path/05074mp05
DOSED FEED Time: 06:47:19 Facility: Battelle Columbus Laboratory Chemical CAS #: 87-86-5 Lock Date: None Cage Range: All Reasons For Removal: All Removal Date Range: All ...
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TR 349 Mouse Pathology Tables 75KB
https://ntp.niehs.nih.gov/data/tables/tr/300s/tr349/path/05073mp11
PAGE: 1 TEST TYPE: CHRONIC ROUTE: DOSED FEED NTP C#: 55378 CONT: N01-ES-38068 CAS: 87-86-5 ... NTP C#: 55378 CONT: N01-ES-38068 CAS: 87-86-5 PATHOLOGIST: R. PERSING S. EUSTIS ...
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Target Organs and Levels of Evidence for TR-483 54KB
https://ntp.niehs.nih.gov/data/tr/400s/tr483levels
(CASRN 87-86-5) in F344/N Rats (Feed Studies) Chemical (Study Title) CASRN Peer Review Date Route/Exposure Levels Study Laboratory Pentachlorophenol, purified 87-86-5 12/10/1997 ...
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Abstract for TR-198 61KB
https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr198
8abs Abstract for TR-198 Bioassay of a Mixture of 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin and 1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin (Gavage) for Possible Carcinogenicity ...
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Actions: RoC Peer Review; Dec. 12-13, 2013 49KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2013/december/actions20131212_508.pdf
Actions from Peer Review of the Draft Report on Carcinogens (RoC) Monographs for ortho-Toluidine and Pentachlorophenol and By-products of its Synthesis December 12 - 13, 2013 The ...
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TR-414: Pentachloroanisole (CASRN 1825-21-4) in F344 Rats and... 15.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr414.pdf
... Isolation and identification o f a conjugated PCP excreted by goldfish. Bull. Jap. Soc. ... Effect o f pe,ntachloroanisole (PCA) and pentachlorophenol (PCP) upon in vitro respiration ...
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Minutes: BSC; June 21-22, 2012 280KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2012/june/bscminutes20120622_508.pdf
... Safety and Health Administration PCP pentachlorophenol PETA People for the ... Gloria Jahnke, ORoC, presented the pentachlorophenol (PCP) draft concept. PCP and its ...
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Protocol for Cancer Assessment of Animal Studies for the RoC... 338KB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/protocols/pcp_animalcancer_508.pdf
! !"#$#%#&'(#"')*+%,"'-..,../,+$'#('-+0/*&'1$230,.'(#"'$4,'5,6#"$'#+')*"%0+#7,+.' 8#+#7"*64'#+'!)!' 9*%:7"#2+3';+(#"/*$0#+' "#$%&'()*+*,(#$*)!-"."/!.0123!45647689!:$');<:$=!:%>!>*<...
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NTP Systematic Evaluation of the Application of Zebrafish in... 36KB
https://ntp.niehs.nih.gov/go/ts-18013
58-89-9 - Lindane 330-55-2 - Linuron 76738-62-0 - Paclobutrazol 87-86-5 - Pentachlorophenol, Dowicide EC-7 87-86-5 - Pentachlorophenol, DP-2 87-86-5 - Pentachlorophenol, purified ...
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Minutes: BSC; April 17-18, 2014 253KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2014/april/minutes20140418_508.pdf
on o-Toluidine and Pentachlorophenol (PCP) and By-products of its ... KSHV Kaposi sarcoma-associated herpes virus PCP pentachlorophenol IRIS Integrated Risk ...
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Minutes: BSC TRRS; April 18, 1988 4.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1988/apr/88apr18trrsmins_508.pdf
8-Methoxypsoralen 298-81-7 Ochratoxin A 303-47-9 Pentachlorophenol, Tecmical and 87-86-5 Oowicide EC-7 Tribromomethane 75-25-2 (BrOfOOform) PREVIOUSLY APPROVED SMIES- NEW DATA ...
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Abstract for TR-123 59KB
https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr123
3abs Abstract for TR-123 Bioassay of 2,7-Dichlorodibenzo-p-dioxin (DCDD) for Possible Carcinogenicity CASRN: 33857-26-0 Chemical Formula: C12H6Cl2O2 Molecular Weight: 253.0834 ...
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Abstract for TR-414 69KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr414
4abs Abstract for TR-414 Toxicology and Carcinogenesis Studies of Pentachloroanisole in F344/N Rats and B6C3F1 Mice (Gavage Studies) CASRN: 1825-21-4 Chemical Formula: C7H3Cl5O ...
