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RoC Background Document for Naphthalene; Sept. 19, 2002 4.0MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/naphthalenepub_508.pdf
... compound, as metabolites (including 1-naphthol, 2-naphthol, naphthoquinones, and ... and related products (tetralin and 1-naphthol), 10% for production of dispersant ...
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Abstract for TR-430 75KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr430
...bis(azo)]bis[5-amino-4-hdroxy-2,7-naphthalenedisulfonato](4-)]di-, tetrasodium salt; 1-naphthol-3,6-disulfonic acid, 2,2'-(3,3'-dihydroxy-4,4'-biphenylylenebisazo)bis[8-amino-, ...
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RoC Profile: Naphthalene; 15th RoC 2021 147KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/naphthalene.pdf
... and (3) spontaneous rearrangement into 1-naphthol and 2-naph- thol, which are converted ... compound or as metabolites, including 1-naphthol, 2-naphthol, naphthoquinones, ...
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TR-500: Naphthalene (CASRN 91-20-3) in F344/N Rats (Inhalation... 8.6MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr500.pdf
... for the metabolites of naphthalene, 1-naphthol, and 2-naphthol, and found metabolites ... for Disease Control and Prevention. 1-Naphthol was detected in 86% of 983 urine ...
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TR-410: Naphthalene (CASRN 91-20-3) in B6C3F1Mice (Inhalation... 8.6MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr410.pdf
... Species' Rat Mouse Rabbit Guinea Pig 1-Naphthol + + + + I-Naphthylsulfuric acid + + + + ... 1-chloronaphthalene and the metabolites 1-naphthol and 2-naphthol showed no mutagenic ...
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Minutes: BSC RoC; Nov. 11, 2008 624KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/draftbackgrounddocs/roc_minutes20021120.pdf
... He said that absorption and disposition studies show metabolites in the urine of workers with good correlation between naphthalene exposure and the amounts of 1-naphthol. ...
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Minutes: BSC TRRS; May 18, 2000 94KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2000/may/trrs18may2000mins_508.pdf
... He noted that the CDC had analyzed urine samples from nearly 1,000 adults for the metabolites of naphthalene, 1-naphthol and 2-naphthol, and found metabolites in over 80% of the ...
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TR-513: Decalin (CASRN 91-17-8) in F344/N Rats and B6C3F1Mice... 11.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr513.pdf
... EC 3.2.1.31; and arylsulfate sulfohydrolase, EC 3.1.6.1; Boehringer Mannheim, GmbH, Germany); 100 µL 0.2 M acetate buffer (pH 5.4); and 3.27 µg 1,2,3,4-tetrahydro-1-naphthol. ...
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RoC Background Document: Phenolphthalein; Oct. 30-31, 1997 2.1MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/phenolphthalein1_508.pdf
... transport in the small and large intestine: Experiments with 1-naphthol and phenolphthalein by luminal and contraluminal administration in the isolated guinea pig mucosa. ...
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RoC Background Document: Dyes Metabolized to Benzidine (Benzidine... 8.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/dyesmetabenzidine_508.pdf
... benzidine with 1 mol H- acid (8-amino-1-naphthol-3,6-disulphonic acid) under acid ... (8-amino- 1-naphthol-3,6-disulphonic acid) under alkaline conditions (Richter, 1951). ...
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Comment: Meat-related exposures; Robert Turesky, University of... 4.6MB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/turesky20161005.pdf
... and ring-oxidation of 2-NA; 2-amino-1-
naphthol is a major ring-oxidation product. 319 ... also formed from 2-imino-1-naphthoquinone, the oxidative product of 2-amino- 1-naphthol. ...
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GMM-12: Genetically Modified Model Report on Phenolphthalein... 768KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/gmm_rpts/gmm12_508.pdf
... Drug metabo- lism and metabolite transport in the small and large intestine: Experiments with 1-naphthol and phenol- phthalein by luminal and contraluminal administration in the ...
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RoC Background Document: Diesel Exhaust Particulates; Dec. 2... 5.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/dieselexhaust_508.pdf
... ROC Background Document for Diesel Exhaust Particulates naphthoic acid (IARC 1989) 1-naphthol (IARC 1989) 2-naphthol (IARC 1989) naphtho[1,8-cd]pyrene 1,3-dione (Schuetzle 1983; ...
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ICCVAM Test Method Evaluation Report on the Reduced LLNA 21.6MB
https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ld/tmer.pdf
... Nitroso Compounds Gerberick 1-Napthol - 90-15-3 144.17 2.54 Solid Hydrocarbons, Cyclic ... 6 Conc. (%) 6 SI Data Source 1-Napthol 90-15-3 AOO + + 1.3 0.1 1.40 0.25 1.00 0.5 1.20 1 ...
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TR-465: Phenolphthalein (CASRN 77-09-8) in F344 Rats and B6C3F1Mice... 18.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr465.pdf
... Drug Lauterbach, metabolism and metabolite transport in the small and large intestine: Experiments with 1-naphthol and phenolphthalein by and luminal contraluminal administration ...
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CERHR Monograph: Potential Human Reproductive and Developmental... 6.3MB
https://ntp.niehs.nih.gov/ntp/ohat/bisphenol/bisphenol.pdf
... Activities increased with age for the isoenzymes catalyzing glucuronidation of bilirubin (B80% of adult levels by 8-15 weeks of age) and 1-naphthol (B30% of adult levels at 8-15 ...
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CERHR Monograph: Soy Infant Formula 122.6MB
https://ntp.niehs.nih.gov/ntp/ohat/genistein-soy/soyformula/soymonograph2010_508.pdf
... Activities increased with age for the isoenzymes catalyzing glucuronidation of bilirubin, primarily UGT1A1 (~80% of adult levels by 8 - 15 weeks of age) and 1-naphthol (~30% of ...
