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TR-513: Decalin (CASRN 91-17-8) in F344/N Rats and B6C3F1Mice... 11.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr513.pdf
REPORT ON THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF DECALIN (CAS NO. 91-17-8) IN F344/N RATS AND B6C3F 1 MICE AND A TOXICOLOGY STUDY OF DECALIN IN MALE NBR RATS (INHALATION ...
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Abstract for TR-513 73KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr513
Abstract for TR-513 Toxicology and Carcinogenesis Studies of Decalin in F344/N Rats and B6C3F1 Mice and a Toxicology Study of Decalin in Male NBR Rats (Inhalation Studies) CASRN: ...
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Target Organs and Levels of Evidence for TR-513 58KB
https://ntp.niehs.nih.gov/data/tr/500s/tr513levels
Target Organs and Levels of Evidence for TR-513 Toxicology and Carcinogenesis Studies of Decalin (CASRN 91-17-8) in F344/N Rats and B6C3F1 Mice and a Toxicology Study of Decalin in ...
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Minutes: BSC TRRS; Sept. 5, 2002 128KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2002/sept/trrs5sept2002mins_508.pdf
.........2 III. Decalin......The original motion was then approved unanimously with 10 votes. Decalin Dr. Po-Chuen ...
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TR-561: Tetralin (CASRN 119-64-2) in F344/N Rats and B6C3F1 Mice... 13.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr561.pdf
... the kidney, and female rats exposed to decalin had increased rates of rare tumors in the ... Sherley, the second primary reviewer, inquired if the presence of decalin contamination in ...
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Spleen - Hyperplasia, Mast Cell - Nonneoplastic Lesion Atlas 287KB
https://ntp.niehs.nih.gov/atlas/nnl/immune-system/spleen/HyperplasiaMastCell
National Toxicology Program. 2005. NTP TR-513. Toxicology and Carcinogenesis Studies of Decalin (CAS No. 91-7-8) in F344/N Rats and B6C3F1 Mice (Feed Studies). NTP, Research ...
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Historical Controls: All Routes and Vehicles for Rats; Studies... 252KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/r_hcrpt_allrte20070300_508.pdf
08/14/97 733 50(5) 28(684) 509.1 Decalin Southern Research Institute 059302007 04/... 08/14/97 734 50(5) 32(700) 346.6 Decalin Southern Research Institute 059302007 04/...
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Historical Controls: All Routes and Vehicles for Mice; Studies... 255KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2006/m_hcrpt_allrte2006_508.pdf
08/28/97 733 50(5) 40(701) 54.4 Decalin Battelle Columbus Laboratory 058812004 ... 08/28/97 735 49(5) 37(708) 61.5 Decalin Battelle Columbus Laboratory 058812004 ...
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Historical Controls: All Routes and Vehicles for Rats; Studies... 270KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2006/r_hcrpt_allrte2006_508.pdf
08/14/97 733 50(5) 28(684) 509.1 Decalin Battelle Columbus Laboratory 058812003 ... 08/14/97 734 50(5) 32(700) 346.6 Decalin Battelle Columbus Laboratory 058812003 ...
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Historical Controls: All Routes and Vehicles for Mice; Studies... 317KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/m_hcrpt_allrte20070300_508.pdf
08/28/97 733 50(5) 40(701) 54.4 Decalin Battelle Columbus Laboratory 059700308 ... 08/28/97 735 49(5) 37(708) 61.5 Decalin Battelle Columbus Laboratory 059700308 ...
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Spleen - Hyperplasia, Mast Cell 303KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/immune/spleen/hypermc/spleen-hyperplasia-mast-cell-pdf_508.pdf
Cell References: National Toxicology Program. 2005. NTP TR-513. Toxicology and Carcinogenesis Studies of Decalin (CAS No. 91-7-8) in F344/N Rats and B6C3F1 Mice (Feed Studies). ...
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Agenda: BSC TRRS; Feb. 25, 2009 125KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2009/feb/trrs25feb2009agenda_508.pdf
a solvent for waxes, polishes, rubber, asphalt, and aromatic hydrocarbons and in paints; derived from naphthalene and structurally related to decalin, which are rodent carcinogens
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Minutes: BSC TRRS; Feb. 25, 2009 76KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2009/feb/minutes_final0209.pdf
... Sherley, the second primary reviewer, inquired if the presence of decalin contamination in ... He suggested that more discussion be provided regarding the concentration of decalin in ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... NE No Evidence NE No Evidence NE No Evidence NE No Evidence TR-513 09/05/02 Decalin 91-17-8 P Clear Evidence NE No Evidence NE No Evidence EE Equivocal Evidence TR-512 09/05/...
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Technical Reports 903KB
https://ntp.niehs.nih.gov/publications/reports/tr
... Report TR-513 PDF (12.03 MB) Toxicology and Carcinogenesis Studies of Decalin (CASRN 91-17-8) in F344/N Rats and B6C3F1 Mice and a Toxicology Study of Decalin in Male NBR ...
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TR-519: Stoddard Solvent IIC (CASRN 64742-88-7) in F344/N Rats... 8.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr519.pdf
... Decalin contamination in lot 00106808 was determined by the analytical chemistry laboratory using GC; approxi- mately 0.56% decalin was detected. To ensure stability, the bulk ...
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Study Reports 1.1MB
https://ntp.niehs.nih.gov/publications/reports
... Report TR-513 PDF (12.03 MB) Toxicology and Carcinogenesis Studies of Decalin (CASRN 91-17-8) in F344/N Rats and B6C3F1 Mice and a Toxicology Study of Decalin in Male NBR ...
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Toxicology/Carcinogenicity 1.1MB
https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox
... TR-513 PDF (12.03 MB) Toxicology and Carcinogenesis Studies of Decalin (CASRN 91-17-8) in F344/N Rats and B6C3F1 Mice and a Toxicology Study of Decalin in Male NBR ...
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TR-347: d-Limonene (CASRN 5989-27-5) in F344/N Rats and B6C3F1Mice... 9.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr347.pdf
... Chemicals studied by other investigators, including decalin (Stone et al., 1987a,b; ... After short-term exposure to decalin, unleaded gasoline, or trimethylpentane, azp-globulin ...
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TR-543: alpha-Methylstyrene (CASRN 98-83-9) in F344/N Rats and... 8.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr543.pdf
... In contrast, decalin and d-limonene, two compounds that have been demonstrated to interact ... Toxicology and Carcinogenesis Studies of Decalin (CAS No. 91-17-8) in F344/N Rats and ...
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TR-361: Hexachloroethane (CASRN 67-72-1) in F344/N Rats (Gavage... 7.2MB
https://ntp.niehs.nih.gov/go/tr361
... a variety of other compounds, including decalin (Kanerva e t al., 1987a,b,c; Stone et ... Short-term expo- sure to decalin, unleaded gasoline, or trimethyl- pentane (Charbonneau et ...
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TR-542: Cumene (CASRN 98-82-8) in F344/N Rats and B6C3F1 Mice... 9.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr542.pdf
... Historical Incidence: Inhalation Studies Cumene 0/50 Decalin 0/49 Divinylbenzene 0/50 ... Historical Incidence: Inhalation Studies Cumene 1/50 1/50 1/50 2/50 Decalin 0/50 1/50 0/50 ...
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TR-552: Propargyl Alcohol (CASRN 107-19-7) in F344/N Rats and... 3.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr552.pdf
... Study Incidence in Controls Historical Incidence: Inhalation Studies Cumene 0/50 Decalin ... Study Incidence in Controls Historical Incidence: Inhalation Studies Cumene 26/50 Decalin ...
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TR-538: Methyl Isobutyl Ketone (CASRN 108-10-1) in F344/N Rats... 13.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr538.pdf
... in Chamber Controls Given NTP-2000 Diet Decalin Divinylbenzene Indium phosphide Methyl ... in Chamber Controls Given NTP-2000 Diet Decalin 19/50 Divinylbenzene 22/50 Indium ...
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TOX-14: p-Chloro-a,a,a-Trifluorotoluene (CASRN 98-56-6) 2.2MB
https://ntp.niehs.nih.gov/ntp/htdocs/st_rpts/tox014.pdf
... 2,2,4-trimethylpentane, limonene, and decalin (Borghoff et al., 1988; Swenberg et al., ... formation in male rats exposed to decalin is dependent on the presence of α2u globulin. ...
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TR-515: Propylene Glycol Mono-t-Butyl Ether (CASRN 57018-52-7... 9.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr515.pdf
... Historical Incidence: Inhalation Studies Decalin 1/50 0/50 1/50 Indium phosphide 0/50 0/50 ... Historical Incidence: Inhalation Studies Decalin Indium phosphide Naphthalene Propylene ...
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TR-534: Divinylbenzene-HP (CASRN 1321-74-0) in F344/N Rats and... 10.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr534.pdf
... Historical Incidence: Inhalation Studies Decalin 1/50 0/50 1/50 Divinylbenzene 0/50 0/50 ... Historical Incidence: Inhalation Studies Decalin 0/50 0/50 0/50 Divinylbenzene 0/49 0/49 ...
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Minutes: BSC; Sept. 17, 2002 762KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2002/september/20020917bscsummmins_508.pdf
... Decalin - used as a solvent, in fuel and stain removal- exposure by inhalation - clear evidence in male rats (kidney and adrenal medulla neoplasms), equivocal evidence in female ...
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TR-518: Triethanolamine (CASRN 102-71-6) in B6C3F1Mice (Dermal... 5.0MB
https://ntp.niehs.nih.gov/go/tr518
... 0/100 Citral (feed) 0/100 2/100 0/100 Decalin (inhalation) 0/50 1/50 0/50 ... 5/100 Citral (feed) 2/100 3/100 5/100 Decalin (inhalation) 0/50 1/50 1/50 ...
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TR-319: 1,4-Dichlorobenzene (CASRN 106-46-7) in F344/N Rats and... 17.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr319.pdf
... cyclo- paraffins, or alkyl aromatic hydrocarbons, and decalin (Mehlman et al., 1984). ... cells of male rats following exposure to decalin were reported to be primarily a-2-micro- ...
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Historical Controls: By Route and Vehicle for Mice; Studies started... 775KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2006/m_hcrpt_rte2006_508.pdf
... 08/28/97 733 50(5) 40(701) 54.4 Decalin Battelle Northwest 058800406 09/27/99 729 ... 08/28/97 735 49(5) 37(708) 61.5 Decalin Battelle Northwest 058800406 09/27/99 731 ...
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Historical Controls: By Route and Vehicle for Rats; Studies started... 733KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2006/r_hcrpt_rte2006_508.pdf
... 08/14/97 733 50(5) 28(684) 509.1 Decalin Battelle Northwest 058800405 09/13/99 729 ... 08/14/97 734 50(5) 32(700) 346.6 Decalin Battelle Northwest 058800405 09/13/99 731 ...
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TR-512: Elmiron (CASRN 37319-17-8) in F344/N Rats and B6C3F1Mice... 12.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr512.pdf
... Citral (feed) 2/100 20/100 13/100 28/100 Decalin (inhalation) 1/50 22/50 10/50 28/50 ... 1/100 5/100 Citral (feed) 1/99 0/99 1/99 Decalin (inhalation) 1/50 1/50 2/50 ...
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TR-523: Diisopropylcarbodiimide (CASRN 693-13-0) in F344/N Rats... 10.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr523.pdf
... Citral (feed) 10/100 1/100 0/100 11/100 Decalin (inhalation) 7/49 0/49 2/49 8/49 ... (feed) 2/100 Citral (feed) 6/99 Decalin (inhalation) 6/49 Dibromoacetic acid ...
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TOX-7: 1,2,4,5-Tetrachlorobenzene (CASRN 95-94-3) 4.1MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox007.pdf
... Teratology 29:21-27. 56. Kanerva, R.L.; Ridder, G.M.; Lefever, F.R.; Alden, C.L. (1987) Comparison of short-term re- nal effects due to oral administration of decalin or d-limonene ...
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TOX-81: α-Pinene (CASRN 80-56-8) Administered by Inhalation... 2.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox081_508.pdf
... The kidney lesions observed in the current study are consistent with those observed in 90-day studies of d-limonene, decalin, and propylene glycol mono-t-butyl ether for which the ...
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TOX-86: Toxicity Studies of Cedarwood Oil (Virginia) (CASRN 8000... 5.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox086_508.pdf
... This mechanism has been demonstrated in 3-month studies with several structurally diverse chemicals, including α-pinene, decalin, and propylene glycol mono-t-butyl ether 58 ; the ...
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Historical Controls: By Route and Vehicle for Mice; Studies started... 790KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/m_hcrpt_rte20070300_508.pdf
... 08/28/97 733 50(5) 40(701) 54.4 Decalin Battelle Northwest 058800406 09/27/99 729 ... 08/28/97 735 49(5) 37(708) 61.5 Decalin Battelle Northwest 058800406 09/27/99 731 ...
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Historical Controls: By Route and Vehicle for Rats; Studies started... 685KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/r_hcrpt_rte20070300_508.pdf
... 08/14/97 733 50(5) 28(684) 509.1 Decalin Battelle Northwest 058800405 09/13/99 729 ... 08/14/97 734 50(5) 32(700) 346.6 Decalin Battelle Northwest 058800405 09/13/99 731 ...
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TR-323: Dimethyl Methylphosphonate (CASRN 756-79-6) in F344/N... 9.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr323.pdf
... naphthas, or light hydrocarbons consisting of paraffins or cycloparaffins or to alkyl aromatic hydrocarbons, decalin (Mehlman et al., 19841, or 1,4-dichlorobenzene (NTP, 1987). ...
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TOX-23: o-,m-, and p- Nitrotoluenes (CASRNs 88-72-2, 99-08-1... 15.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox023.pdf
... Schaeffer, D.J., Mattie, D.R., and Alden, C.L. (1990) Lysosomal changes in renal proximal tubular epithelial cells of male Sprague Dawley rats following Decalin exposure. Toxicol. ...
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TR-514: trans-Cinnamaldehyde (Microencapsulated) (CASRN 14371... 8.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr514.pdf
... 11/100 Citral (feed) 7/100 1/100 8/100 Decalin (inhalation) 0/50 0/50 0/50 ... (feed) 4/100 Citral (feed) 0/100 Decalin (inhalation) 0/50 p,pN-Dichlorodiphenyl ...
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TR-476: Primidone (CASRN 125-33-7) in F344/N Rats and B6C3F1Mice... 13.4MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr476.pdf
THE TOXICOLOGY AND CARCINOGENESIS STUDIES OF PRIMIDONE (CAS NO. 125-33-7) IN F344/N RATS AND B6C3F 1 MICE (FEED STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research ...
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TR-527: Malachite Green Chloride and Leucomalachite Green (CASRNs... 7.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr527.pdf
... 426 Coumarin 422 CS2 377 Cytembena 207 D&C Red No. 9 225 D&C Yellow No. 11 463 Decalin 513 Decabromodiphenyl Oxide 309 Diallyl Phthalate (Mice) 242 Diallyl Phthalate (Rats) ...