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TR-500: Naphthalene (CASRN 91-20-3) in F344/N Rats (Inhalation... 8.6MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr500.pdf
NAPHTHALENE (CAS NO. 91-20-3) IN F344/N RATS (INHALATION STUDIES) NATIONAL TOXICOLOGY PROGRAM P.O. Box 12233 Research Triangle Park, NC 27709 December 2000 NTP TR 500 NIH ...
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TR-410: Naphthalene (CASRN 91-20-3) in B6C3F1Mice (Inhalation... 8.6MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr410.pdf
TOXICOLOGY PROGRAM Technical Report Series No. 410 TOXICOLOGY AND CARCINOGENESIS STUDIES OF NAPHTHALENE (CAS NO. 91-20-3) IN B6C3Fl MICE (INHALATION STUDIES) U . S . DEPARTMENT OF ...
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RoC Background Document for Naphthalene; Sept. 19, 2002 4.0MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/naphthalenepub_508.pdf
FINAL Report on Carcinogens Background Document for Naphthalene September 19, 2002 ... 9/19/02 RoC Background Document for Naphthalene FOREWORD The Report on Carcinogens ...
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RoC Profile: Naphthalene; 15th RoC 2021 147KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/naphthalene.pdf
Naphthalene CAS No. 91-20-3 Reasonably anticipated to be a human carcinogen First listed in the Eleventh Report on Carcinogens (2004) Carcinogenicity Naphthalene is reasonably ...
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Abstract for TR-500 69KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr500
Abstract for TR-500 Toxicology and Carcinogenesis Studies of Naphthalene in F344/N Rats (Inhalation Studies) CASRN: 91-20-3 Chemical Formula: C10H8 Molecular Weight: 128.18 ...
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Abstract for TR-410 63KB
https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr410
Abstract for TR-410 Toxicology and Carcinogenesis Studies of Naphthalene in B6C3F1 Mice (Inhalation Studies) CASRN: 91-20-3 Chemical Formula: C10H8 Molecular Weight: 128.16 ...
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Abstract for TER91006 61KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter91006
6abs Abstract for TER91006 Developmental Toxicity Studies of Naphthalene in Sprague Dawley (CD) Rats CASRN: 91-20-3 Chemical Formula: C10H8 Molecular Weight: 128.173 Report Date: ...
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Abstract for TER91021 60KB
https://ntp.niehs.nih.gov/publications/abstracts/dev/ter91021
1abs Abstract for TER91021 Developmental Toxicity of Naphthalene in New Zealand White Rabbits CASRN: 91-20-3 Chemical Formula: C10H8 Molecular Weight: 128.173 Report Date: July ...
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Abstract for TR-561 77KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr561
CASRN: 119-64-2 Chemical Formula: C10H12 Molecular Weight: 132.21 Synonyms/Common Names: Benzocyclohexane; delta 5,7,9-naphthalene; naphthalene 1,2,3,4-tetrahydride; ...
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Target Organs and Levels of Evidence for TR-410 57KB
https://ntp.niehs.nih.gov/data/tr/400s/tr410levels
Target Organs and Levels of Evidence for TR-410 Toxicology and Carcinogenesis Studies of Naphthalene (CASRN 91-20-3) in B6C3F1 Mice (Inhalation Studies) Chemical (Study Title) ...
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Target Organs and Levels of Evidence for TR-500 58KB
https://ntp.niehs.nih.gov/data/tr/500s/tr500levels
Target Organs and Levels of Evidence for TR-500 Toxicology and Carcinogenesis Studies of Naphthalene (CASRN 91-20-3) in F344/N Rats (Inhalation Studies) Chemical (Study Title) ...
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Minutes: BSC TRRS; May 18, 2000 94KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2000/may/trrs18may2000mins_508.pdf
Chloral Hydrate 302-17-0 Gavage 3 Indium Phosphide 22398-80-7 Inhalation 5 Naphthalene 91-20-3 Inhalation 6 Sodium Nitrite 7632-00-0 Drinking Water 8 p,p'-Dichlorodiphenyl ...
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Minutes: BSC RoC; Nov. 11, 2008 624KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/draftbackgrounddocs/roc_minutes20021120.pdf
......... 3 Naphthalene ......Frumkin seconded the motion, which was accepted unanimously with 9 yes votes. Naphthalene ...
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Abstract for TR-513 73KB
https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr513
Full Report PDF Abstract Decalin is used as an industrial solvent for naphthalene, fats, resins, oils, and waxes. It is also used as a substitute for turpentine in lacquers, ...
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TR-561: Tetralin (CASRN 119-64-2) in F344/N Rats and B6C3F1 Mice... 13.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr561.pdf
... Background Tetralin is widely used as a solvent for naphthalene, waxes, resins, oils, ... Synonyms: Benzocyclohexane; ) 5,7,9 -naphthalene; naphthalene 1,2,3,4-tetrahydride; ...
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Minutes: BSC TRRS; March 11, 1991 723KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1991/mar/trrs11mar1991mins_508.pdf
Pigment Red 23 2,4-Diaminophenol D i h y d r o c h l o r i d e Furan Naphthalene Q u e r c ... Feed 137-09-7 Gavage 110-00-9 Gavage 91-20-3 I n h a l a t i o n 117-39-5 Feed ...
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TR-143: 1,5-Naphthalenediamine (CASRN 2243-62-1) 4.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr143.pdf
... Fischer 344 rats and B6C3F1 mice. 1,5-Naphthalene- diamine was administered in the feed, ... RATS 21 SURVIVAL COMPARISONS OF 1,5-NAPHTHALENE- DIAMINE CHRONIC STUDY RATS 22 GROWTH ...
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RoC Profile: Coal Tars and Coal-Tar Pitches; 15th RoC 2021 134KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/coaltars.pdf
... including benzene, naphthalene, and other polycyclic aromatic hydrocarbons (PAHs). ... viscous liquids or semisolids with a characteristic naphthalene-like odor (ATSDR 2002). ...
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Agenda: BSC RoC; Nov. 19-20, 2002 50KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/meetings/2002/nov2002rocagenda.pdf
for 1-Amino,4-dibromoanthraquinone (81-49-2) Listing in the 11th Report Naphthalene (91-20-3) Listing in the 11th Report Selected Heterocyclic Amines Listing in the 11th ...
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TR-064: 1-Nitronaphthalene (CASRN 86-57-7) 3.8MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr064.pdf
... IN RATS TREATED WITH 1-NITRO- NAPHTHALENE C-l APPENDIX D SUMMARY OF THE INCIDENCE OF NONNEOPLASTIC LESIONS IN MICE TREATED WITH 1-NITRO- NAPHTHALENE D-l vii LIST OF ILLUSTRATIONS ...
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TR-513: Decalin (CASRN 91-17-8) in F344/N Rats and B6C3F1Mice... 11.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr513.pdf
... Decalin is used as an industrial solvent for naphthalene, fats, resins, oils, and waxes. ... by complete catalytic hydrogenation of naphthalene or tetrahydronaphtha lene (tetralin). ...
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Polycyclic Aromatic Compounds 83KB
https://ntp.niehs.nih.gov/whatwestudy/topics/pacs
... of marine diesel fuel and JP-5 Naphthalene (TR-410 and TR-500) Napthalene (a white ... Developmental Toxicity Abstract Studies on Naphthalene Developmental Toxicity Abstract ...
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Appendix G; 15th RoC 2021 73KB
https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf
... Michler's Ketone 91-08-7 (2,6-toluene diisocyanate) see Toluene Diisocyanates 91-20-3 see Naphthalene 91-23-6 see o-Nitroanisole 91-59-8 see 2-Naphthylamine 91-94-1 ...
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Agenda: BSC TRRS; Feb. 25, 2009 125KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2009/feb/trrs25feb2009agenda_508.pdf
a solvent for waxes, polishes, rubber, asphalt, and aromatic hydrocarbons and in paints; derived from naphthalene and structurally related to decalin, which are rodent carcinogens
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Nose, Olfactory Epithelium, Glands - Metaplasia - Nonneoplastic... 297KB
https://ntp.niehs.nih.gov/atlas/nnl/respiratory-system/nose/OlfactoryEpitheliumGlands-Metaplasia
Long PH, Herbert RA, Peckham JC, Grumbein SL, Shackelford CC, Abdo Kl. 2003. Morphology of nasal lesions in F344/N rats following chronic inhalation exposure to naphthalene vapors. ...
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Eye, Cornea - Metaplasia, Goblet Cell - Nonneoplastic Lesion... 288KB
https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/eye/Cornea-MetaplasiaGobletCell
National Toxicology Program. 1992. NTP TR-410. Toxicology and Carcinogenesis Studies of Naphthalene (CAS No. 91-20-3) in B6C3F1 Mice (Inhalation Studies). NTP, Research Triangle ...
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Eye, Cornea - Metaplasia 243KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/special_senses/eye/crmeta/eye-cornea-metaplasia_508.pdf
Program. 1992. NTP TR-410. Toxicology and Carcinogenesis Studies of Naphthalene (CAS No. 91-20-3) in B6C3F 1 Mice (Inhalation Studies). NTP, Research Triangle Park, NC. ...
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RoC Profile: Coke-Oven Emissions; 15th RoC 2021 121KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/cokeovenemissions.pdf
... Coke-oven gas tar includes pyridine, tar acids, naphthalene, creosote oil, and coal-tar ... toluene, naphthalene, sulfur, and ammonium sulfate) (IARC 1984, Kaegi et al. 2000). ...
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Historical Controls: All Routes and Vehicles for Rats; Studies... 270KB
https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2006/r_hcrpt_allrte2006_508.pdf
... 03/28/96 733 49(5) 24(681) 507.1 Naphthalene Southern Research Institute 050520308 ... 03/28/96 734 49(5) 28(700) 325.2 Naphthalene Southern Research Institute 050520308 ...
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RR-11: The Chemical and Physical Characterization of Recycled... 3.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/results/pubs/rr/reports/rr11_508.pdf
...4,4,-trimethylpentene (~19.5 minutes), naphthalene (~51.5 minutes), methyl vinyl ketone ... 0.00994 0.00814 0.00904 93.6 Naphthalene 0.00689 0.00599 0.00644 99.9 Styrene ...
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Lung - Vacuolization, Cytoplasmic - Nonneoplastic Lesion Atlas 294KB
https://ntp.niehs.nih.gov/atlas/nnl/respiratory-system/lung/VacuolizationCytoplasmic
Plopper CG, Van Winkle LS, Fanucchi MV, Malburg SR, Nishio SJ, Chang A, Buckpitt AR. 2001. Early events in naphthalene-induced acute Clara cell toxicity. II. Comparison of ...
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Eye - Phthisis Bulbi - Nonneoplastic Lesion Atlas 293KB
https://ntp.niehs.nih.gov/atlas/nnl/special-senses-system/eye/PhthisisBulbi
National Toxicology Program. 1992. NTP TR-410. Toxicology and Carcinogenesis Studies of Naphthalene (CAS No. 91-20-3) in B6C3F1 Mice (Inhalation Studies). NTP, Research Triangle ...
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Lung - Vacuolization, Cytoplasmic 313KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/respiratory/lung/vaccyto/lung-vacuolization-cytoplasmic-508.pdf
... Cytoplasmic References: Plopper CG, Van Winkle LS, Fanucchi MV, Malburg SR, Nishio SJ, Chang A, Buckpitt AR. 2001. Early events in naphthalene-induced acute Clara cell toxicity. ...
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Eye - Phthisis Bulbi 383KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/special_senses/eye/phthisis/eye-pthisis-bulbi_508.pdf
... Bulbi References: National Toxicology Program. 1992. NTP TR-410. Toxicology and Carcinogenesis Studies of Naphthalene (CAS No. 91-20-3) in B6C3F 1 Mice (Inhalation Studies). ...
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NTP Technical Reports Index 1.5MB
https://ntp.niehs.nih.gov/data/tr
... NE No Evidence NE No Evidence NE No Evidence NE No Evidence TR-500 05/18/00 Naphthalene 91-20-3 P Clear Evidence P Clear Evidence NT Chemical Not Tested in Species/Sex NT ...
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Minutes: BSC TRRS; Jan. 08, 1986 1.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1986/minutesbsctrrs19860108_508.pdf
... Benjamin Jackson, CFSAN, presented an overview of the toxicolog of Yellow 6 which chemically is the disodium salt of 6-hydroxy-5-((4-sulfophenyl)azo)-2-naphthalene sulfonic acid. ...
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Nose, Olfactory Epithelium, Glands - Metaplasia 520KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/respiratory/nose/oepgmeta/nose-olfactory-epithelium-glands-metaplasia-pdf_508.pdf
... Long PH, Herbert RA, Peckham JC, Grumbein SL, Shackelford CC, Abdo Kl. 2003. Morphology of nasal lesions in F344/N rats following chronic inhalation exposure to naphthalene vapors. ...
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Nose, Epithelium - Hyperplasia - Nonneoplastic Lesion Atlas 300KB
https://ntp.niehs.nih.gov/atlas/nnl/respiratory-system/nose/Epithelium-Hyperplasia
... National Toxicology Program. 1992. NTP TR-410. Toxicology and Carcinogenesis Studies of Naphthalene (CAS No. 91-20-3) in B6C3F1 Mice (Inhalation Studies). NTP, Research Triangle ...
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RoC Background Document: Diesel Exhaust Particulates; Dec. 2... 5.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/dieselexhaust_508.pdf
... 182 28013-11-8 30-91 C 4 Naphthalene 184 2717-39-7 285-351 ... napthaldehyde isomers (Newton 1982) naphthalene (ARB 1993; Jensen 1983; Yergey 1982) ...
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Protocol for a Systematic Review of Traffic-Related Air Pollution... 1.3MB
https://ntp.niehs.nih.gov/ntp/ohat/airpollchildhealth/protocol_20160616_508.pdf
... key: benzene, 1,3-butadiene, formaldehyde, acetaldehyde, acrolein, polycyclic organic matter, naphthalene, and diesel exhaust (http://www3.epa.gov/otaq/toxics-regs.htm#02262007). ...
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Poster: Scoping review of polycyclic aromatic hydrocarbons (PAH... 19.6MB
https://ntp.niehs.nih.gov/ntp/results/pubs/posters/wang_sot20200315.pdf
... Dibenzo[a,h]pyrene Indeno[1,2,3-cd]pyrene Benzo[j]fluoranthene Dibenz[a,h]anthracene Dibenzo[a,i]pyrene 5-Methylchrysene 1 listed since 2004 Naphthalene A n t h r a c e n e B e n z ...
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Ovary - Inflammation - Nonneoplastic Lesion Atlas 305KB
https://ntp.niehs.nih.gov/atlas/nnl/reproductive-system-female/ovary/Inflammation
... National Toxicology Program. 2000. NTP TR-500. Toxicology and Carcinogenesis Studies of Naphthalene (CAS No. 91-20-3) in F344/N Rats (Inhalation Studies). NTP, Research Triangle ...
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Nose, Epithelium - Hyperplasia 482KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/respiratory/nose/ephyp/nose-epithelium-hyperplasia-pdf_508.pdf
.../go/8892 National Toxicology Program. 1992. NTP TR-410. Toxicology and Carcinogenesis Studies of Naphthalene (CAS No. 91-20-3) in B6C3F1 Mice (Inhalation Studies). ...
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Poster: Use of Survey Sampling to Develop an Evidence Map of... 1.7MB
https://ntp.niehs.nih.gov/ntp/results/pubs/posters/wang_gems_20221101.pdf
... Naphthalene 33 (5.76 - 112.35) 66 (20.95 - 160.03) 0 (0 - 56.56) 0 (0 - 56.56) 181 (96.96 ... (not shown, 4832 references) 2. Naphthalene 3. Pyrene Number of references Next steps... ...
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Public Health Impact 1.5MB
https://ntp.niehs.nih.gov/media/impact
... Type: Final rule April 30, 2020 85 FR 24174 75-07-0 71-43-2 106-99-0 50-00-0 91-20-3 2020 ... NTP (National Toxicology Program). Naphthalene. Report on Carcinogens, Twelfth Edition.; ...
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National Institute of Environmental Health Sciences: Suramya... 198KB
https://www.niehs.nih.gov/research/atniehs/dtt/assoc/opo/staff/suramya
... Y., Rappaport S.M. (2009) Urinary naphthalene and phenanthrene as biomarkers of ... Y., Rappaport S.M. (2009) Urinary naphthalene and phenanthrene as biomarkers of ...
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RoC Background Document for 1-Amino-2,4-dibromoanthraquinone... 941KB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/adbaqpub_no_appendices_508.pdf
... that can be derived from aromatic molecules such as benzene, naphthalene, and anthracene. ... that can be derived from aromatic molecules such as benzene, naphthalene, and anthracene. ...
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Ovary - Inflammation 759KB
https://ntp.niehs.nih.gov/sites/default/files/nnl/female_reproductive/ovary/inflamm/ovary-inflammation-pdf-508.pdf
.../go/6969 National Toxicology Program. 1992. NTP TR-410. Toxicology and Carcinogenesis Studies of Naphthalene (CAS No. 91-20-3) in B6C3F 1 Mice (Inhalation Studies). ...
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TR-534: Divinylbenzene-HP (CASRN 1321-74-0) in F344/N Rats and... 10.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr534.pdf
... product. o-Diethylbenzene in the starting material is converted to naphthalene. ... area percent of 0.13%; the retention time of this minor peak matched that of naphthalene. ...
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Listed Substances; 15th RoC 2021 76KB
https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf
... (see N-Nitrosamines: 15 Listings) Metronidazole Michler's Ketone Mirex Naphthalene Nickel, Metallic (see Nickel Compounds and Metallic Nickel) Nitrilotriacetic Acid ...