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38 results found for "91-22-5".
  1. RoC Profile: Heterocyclic Amines (Selected); 15th RoC 2021 184KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/heterocyclicamines.pdf

    . 2-Amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ) was first listed in the Eleventh ... (2004). . 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) was first listed in the Tenth ...

  2. Minutes: BSC RoC; Nov. 11, 2008 624KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/draftbackgrounddocs/roc_minutes20021120.pdf

    2-Amino-3,4-dimethylamidazo{4,5-f}quinoline (MeIQ); 2-Amino-3,8-dimethylimidazo{4,5-... Selected Heterocyclic Amines (HCAs): 2-Amino-3,4-dimethylamidazo{4,5-f}quinoline (MeIQ) ; ...

  3. Background Document for Selected Heterocyclic Amines: PhIP, MeIQ... 3.3MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/hcaspub_508.pdf

    ... 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ), and 2-amino-3,8- ... Another HCA, 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) was reviewed by the National ...

  4. 15th RoC: Appendix F 174KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf

    2-amino-3,4-dimethylimidazo[4,5-f]quinoline see Heterocyclic Amines (Selected) ... 2-amino-3-methyl-3H-imidazo(4,5-f)quinoline see Heterocyclic Amines (Selected), ...

  5. TR-456: 1,2-Dihydro-2,2,4-Trimethylquinoline (CASRN 147-47-7... 17.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr456.pdf

    ... It was selected for evaluation because it is a derivative of quinoline, a known rodent ...,4-trimethylquinoline for 13 weeks. . . quinoline by dermal application in acetone for 2 ...

  6. TOX-8: D&C Yellow No. 11 (CASRN 8003-22-3) 2.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox008.pdf

    ... SL; Oil Yellow SIS; Petrol Yellow C; Quinolin Yellow A Spirit Soluble; Quinoline Yellow Base; Quinoline Yellow Spirit Soluble; Quinoline Yellow SS; Solvent Yellow 33; Waxoline ...

  7. Comment: Meat-related exposures; Robert Turesky, University of... 4.6MB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/turesky20161005.pdf

    ... to form 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino- 3-methylimidazo[4,5-f]... imidazo[4,5-f]quinoline and 2-nitrosoamino-3,8-dimethylimidazo- [4,5-f]quinoxaline. ...

  8. Agenda: BSC RoC; Nov. 19-20, 2002 50KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/meetings/2002/nov2002rocagenda.pdf

    Listing in the 11th Report (three nominations)\ 2-Amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ) (77094-11-2) 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) ...

  9. TR-463: D&C Yellow No. 11 (CASRN 8003-22-3) in F344 Rats (Feed... 12.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr463.pdf

    ... Yellow 33, Nitro Fast Yellow SL, Oil Yellow SIS, Petrol Yellow C, Quinoline Yellow A Spirit Soluble, Quinoline Yellow Base, Quinoline Yellow Spirit Soluble, Quinoline Yellow SS, ...

  10. Abstract for TR-456 77KB

    https://ntp.niehs.nih.gov/publications/reports/tr/400s/tr456

    It was selected for evaluation because it is a derivative of quinoline, a known rodent carcinogen, and was regarded as having potential carcinogenic activity. Because of the ...

  11. Completed RoC Evaluations 119KB

    https://ntp.niehs.nih.gov/whatwestudy/assessments/cancer/completed/roc

    Request Archived Materials 2-Amino-3,4-dimethylimidazo[4-5-f]quinoline (MeIQ) Reasonably ... Background Document Request Archived Materials 2-Amino-3-methylimidazo[4,5-f]quinoline ...

  12. Listed Substances; 15th RoC 2021 76KB

    https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf

    ... 2-Amino-3,4-dimethylimidazo[4,5-f] quinoline (see Heterocyclic Amines [Selected]) ... 2-Amino-3-methylimidazo[4,5-f]quinoline (see Heterocyclic Amines [Selected]) ...

  13. TR-276: 8-Hydroxyquinoline (CASRN 148-24-3) in F344/N Rats and... 8.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr276.pdf

    ... unknown) fed 100-250mg/kg 8-hydroxy- quinoline for 30-40days (Galea and Popa, 1972). ... Neurotoxic effects of halogenated 8-hydroxy- quinoline (5-chloro-7-iodo-8-hydroxyquinoline...

  14. RoC Profile: Nitrobenzene; 15th RoC 2021 133KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/nitrobenzene.pdf

    ... Most nitrobenzene (97%) is used in the manufacture of aniline (IARC 1996, HSDB 2009). Miscellaneous uses include the manufacture of benzidine, quinoline, azobenzene, pyroxylin ...

  15. Appendices A-G; 15th RoC 2021 448KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf

    ... 2-amino-3,4-dimethylimidazo[4,5-f]quinoline see Heterocyclic Amines (Selected) ... 2-amino-3-methyl-3H-imidazo(4,5-f)quinoline see Heterocyclic Amines (Selected), ...

  16. Comment: Meat-related exposures; Claire Kruger, Spherix Consulting... 87KB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/kruger20161010.pdf

    ... ML, Chang WC, Zenser TV. Hemin potentiates nitric oxide-mediated nitrosation of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) to 2-nitrosoamino-3- methylimidazo[4,5-f]quinoline. ...

  17. RoC Background Document for Nitrobenzene; Sept. 19, 2002 1.3MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/nbpub_no_appendices_508.pdf

    ... of compounds including benzidine and quinoline, in the production of isocyanates, ... Nitrobenzene also is used in the manufacture of benzidine, quinoline, azobenzene, and ...

  18. Appendix G; 15th RoC 2021 73KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf

    ... (2-amino-3-methylimidazo-[4,5-f]quinoline [IQ]) see Heterocyclic Amines (Selected) 77094-11-2 (2-amino-3,4-dimethylimidazo[4,5-f]quinoline [MeIQ]) see Heterocyclic Amines ...

  19. RoC Background Document: Tobacco Smoking; Dec. 2-3, 1998 3.5MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/environmentalts_noapps_508.pdf

    ... Aromatic Compounds Benzene Fluoranthene Benzo[a]pyrene o-Toluidine 2-Napthylamine Quinoline 400-500 µg 1.3 µg 0.2 µg 3.0 µg 0.06 µg 18 µg 50 µg 0.27 µg 0.04 µg 0.16 µg ...

  20. ICCVAM Evaluation of In Vitro Test Methods for Detecting Potential... 10.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/endo_docs/edfinalrpt0503/edfinrpt.pdf

    ... 1 Terpene 1 Pyrimidine 3 Triazine 1 Quinoline 1 Triazole 1 Resorcylic acid lactone 1 ... Apomorphine 58-00-4 Heterocycle; Quinoline Pharmaceutical Atrazine 1912-24-9 ...

  21. Minutes: BSC; June 29, 2004 883KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2004/june/20040629_508.pdf

    ... Three heterocyclic amines 2-Amino--methyl-6-phenylimidazo[4,5-b] pyridine (PhIP), 2- Amino-3,4-dimethylimidazo[4,5-f] quinoline (MeIQ), and 2-Amino-3,8- dimethylimidazo[4,5-f] ...

  22. National Toxicology Program, Board of Scientific Counselors 106KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2001/may/2001052501bscsummmins_508.pdf

    ... The initial list of nominations for the 11 th Edition of the RoC includes the following: 1-Amino- 2,4-dibromoanthraquinone, 2-Amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ), ...

  23. TR-584: Indole-3-Carbinol (CASRN 700-06-1) in F344/N Rats and... 4.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr584_508.pdf

    ... benzo[a] pyrene, 2-amino-3-methylimidazo[4,5-f]quinoline, and tobacco smoke 66-71 . ... of 2- amino-3-methylimidazo[4,5-f]quinoline-DNA adducts by indole-3-carbinol: ...

  24. TR-565: Milk Thistle Extract (CASRN 84604-20-6) in F344/N Rats... 7.6MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr565.pdf

    ... induced in human sperm exposed in vitro to the known food mutagens 3-amino-1-methyl-5H-pyrido [4,3-b] indole and 2-amino-3-methylimidazo [4,5-f] quinoline (Anderson et al., 1997). ...

  25. TR-143: 1,5-Naphthalenediamine (CASRN 2243-62-1) 4.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr143.pdf

    ... International Statistical Institute Review 39:148-169, 1971. Hall, C.M., "Pharmaceutical Compositions Containing 1,4,7,10-Tetra- hydro-1,7-dioxoquino-8,7-h quinoline-3,9-dicarboxyl...

  26. ICCVAM Test Method Evaluation Report on the Reduced LLNA 21.6MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ld/tmer.pdf

    ... nitro-5-[3-(trifluoromethyl)- phenoxy]quinoline - 189746-15-4 408.34 6.09 Solid ... trifluoromethylphenoxy) quinoline - 106635-87-4 593.61 8.70 Solid ...

  27. TR-359: 8-Methoxypsoralen (CASRN 298-81-7) in F344/N Rats (Gavage... 7.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr359.pdf

    ... Cryobiology 11:160- 169. 10. Ashwood-Smith, M.J.; Towers, G.H.N.; Abramowski, Z.; Poulton, G.A.; Liu, M. (1982) PhotDbiological studies with dictamnine, a furo- quinoline alkaloid. ...

  28. TR-044 In Vitro Carcinogenesis: Guide to the Literature, Recent... 18.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr044.pdf

    ... Here I described the outline of our experimental procedures and results of the chemical transformation. CHEMICALS 4-nitorquinoline-1-oxide (UNQO) and 4-amino-quinoline- 1-oxide ...

  29. RoC Background Document for Naphthalene; Sept. 19, 2002 4.0MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/naphthalenepub_508.pdf

    ... LaVoie, E.J., S. Dolan, P. Little, C.X. Wang, S. Sugie, and A. Rivenson. 1988. Carcinogenicity of quinoline, 4- and 8-methylquinoline and benzoquinolines in newborn mice and rats. ...

  30. Background Document: RoC: Captafol; 2010 1.1MB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/captafol_final_508.pdf

    ... Yamamoto A, Cui L, Ogiso T, Ito N, Shirai T. 1996. Low susceptibility of the spontaneously hypertensive rat (SHR) to quinoline- induction of hepatic hemangioendothelial sarcomas. ...

  31. TR-470: Pyridine (CASRN 110-86-1) in F344/N Rats, Wistar Rats... 16.2MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr470.pdf

    ... Guidelines for combining neoplasms for evaluation of rodent carcinogenesis studies. JNCI 76, 283-289. McFee, A.F. (1989). Genotoxic potency of three quinoline compounds evaluated ...

  32. TR-553: Photococarcinogenesis Study of Aloe Vera[CASRN 481-72... 6.7MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr553.pdf

    ... T. (1990). Formation of a nitro derivative of 2-amino-3,4- dimethylimidazo[4,5-f]quinoline by photo-irradiation. Carcinogenesis 11, 869-871. Hunter, D., and Frumkin, A. (1991). ...

  33. TR-601: Di(2-ethylhexyl) Phthalate Administered in Feed to Sprague... 4.5MB

    https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr601_508.pdf

    ... analysis of liver DNA in gpt delta transgenic rats treated with the hepatocarcinogens N-nitrosopyrrolidine, 2-amino-3-methylimidazo[4,5-f]quinoline, and di(2- ethylhexyl)phthalate. ...

  34. Draft TR-601: Di(2-ethylhexyl) Phthalate (CASRN 117-81-7) Administered... 3.6MB

    https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2021/april/tr601_508.pdf

    ... of liver DNA in gpt delta transgenic rats treated with the 36 hepatocarcinogens N-nitrosopyrrolidine, 2-amino-3-methylimidazo[4,5-f]quinoline, and di(2- 37 ethylhexyl)phthalate. ...

  35. ICCVAM Test Method Evaluation Report on the Applicability Domain... 16.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-ad/tmer-revmay2012.pdf

    ... fluorophenoxy)quinoline 124495-18-7 308.14 5.69 Liquid Heterocyclic Compounds Quinoxyfen / 5,7-dichloro-4-(4- fluorophenoxy)quinoline/ 124495-18-7 308.14 5.69 ...

  36. DART-08: Modified One-Generation Study of Bisphenol AF (CASRN... 5.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/dart/dart08_508.pdf

    ... (dimethyl sulfoxide). b The positive controls in the absence of metabolic activation were 2-nitrofluorene (TA98), sodium azide (TA100), and 4-nitro- quinoline-N-oxide (E. coli). ...

  37. Usefulness and Limitations of the LLNA for Potency Categorization... 25.3MB

    https://ntp.niehs.nih.gov/iccvam/docs/immunotox_docs/llna-pot/tmer.pdf

    ... Intermediate in chemical synthesis Quinoxyfen SC 5,7-dichloro-4-(4- fluorophenoxy) quinoline 124495-18-7 308.10 5.69 Liquid NA Formulations; Heterocyclic compounds Herbicide ...

  38. Peer Review Evaluation Report: Oral Up-and-down Procedure (NIH... 2.1MB

    https://ntp.niehs.nih.gov/iccvam/docs/acutetox_docs/udpproc/udpfin01/vol_2.pdf

    ... ammonium salt of fluorinated alkylaryl amide. 721.9080 Nitro methyl quinoline. 721.9100 Substituted quinoline. 721.9220 Reaction products of secondary alkyl amines with a ...

 
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