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Abstract for TOX-46 68KB
https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox046
In most cases, methapyrilene hydrochloride was replaced by pyrilamine maleate, a ... could also be compared with similar data on the structural analogue pyrilamine maleate. ...
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TOX-46: Hepathe Liver Carcinogen Methapyrilene Hydrochloride... 1.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox046.pdf
...thyl-aminoethyl)-2-thenylamino]pyridine PYRILAMINE MALEATE CAS No. 59-33-6 Chemical ... In most cases, methapyrilene hydrochloride was replaced by pyrilamine maleate, a ...
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TR-317: Chlorpheniramine Maleate (CASRN 113-92-8) in F344/N Rats... 10.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr317.pdf
... hydro- chloride were inactive, whereas pyrilamine maleate and tripelennamine ... maleate, methapyrilene hy- drochloride, pyrilamine maleate, and tripelen- namine ...
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TR-588: Glycidamide (CASRN 5694-00-8) in F344/N Nctr Rats and... 3.6MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr588_508.pdf
... 0/40 (0.0%) 0/40 (0.0%) 0/40 (0.0%) Pyrilamine (July 1991) Diet 0/42 (0.0%) 0/42 ... (June 1991) Diet 3/47 (6.4%) Pyrilamine (July 1991) Diet 2/48 (4.2%) Fumonisin ...
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TR-575: Acrylamide (CASRN 79-06-1) in F344/N Rats and B6C3F1... 9.9MB
https://ntp.niehs.nih.gov/go/tr575
... 2001) Diet 0/47 (0.0%) 0/47 (0.0%) Pyrilamine (July 1991) Diet 0/42 (0.0%) 0/42 ... Green (June 2001) Diet 2/48 (4.2%) Pyrilamine (July 1991) Diet 2/48 (4.2%) ...
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TR-355: Diphenhydramine Hydrochloride (CASRN 147-24-0) in F344... 10.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr355.pdf
... NTP for carcinogenicity include doxylamine, pyrilamine, tripelennamine, and triprolidine. ... Ther. 95:45-52. 47 Lijinsky, W. (1984a) Chronic toxicity tests of pyrilamine maleate and ...
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Minutes: BSC; Sept. 17, 2002 762KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/2002/september/20020917bscsummmins_508.pdf
... Tennant briefly described NCT studies with methapyrilene, a species-specific carcinogen, and pyrilamine, its non-carcinogenic analog. Methapyrilene has specific effects on the ...
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TR-527: Malachite Green Chloride and Leucomalachite Green (CASRNs... 7.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr527.pdf
... 0/48 Gentian violet 1/163 0/163 1/163 Pyrilamine 0/42 0/42 0/42 Sulfamethazine 0/170 0/... B 1 33/48 Gentian violet 160/177 Pyrilamine 39/48 Sulfamethazine 161/179 ...
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TR-502: Chloral Hydrate (CASRN 302-17-0) in B6C3F1Mice (Gavage... 8.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr502.pdf
... Study Adenoma or Carcinoma Doxylamine 2/38 Fumonisin B 1 0/29 Pyrilamine 2/45 ... Study Incidence in Controls Doxylamine 13/48 Fumonisin B 1 20/47 Pyrilamine 10/48 ...
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TR-510: Urethane + Ethanol (CASRNs. 51-79-6 & 64-17-5) in F344... 17.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr510.pdf
... 1/48 Doxylamine 0/48 Fumonisin B 1 0/48 Pyrilamine 0/47 Sulfamethazine 3/187 Triprolidine ... 4/48 9/48 Fumonisin B 1 9/47 4/47 12/47 Pyrilamine 10/46 3/46 13/46 Sulfamethazine 25/185 ...
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TR-503: Chloral Hydrate (Ad Libitum and Dietary Controlled) ... 5.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr503.pdf
... 4/48 9/48 Fumonisin B 1 9/47 4/47 12/47 Pyrilamine 10/46 3/46 13/46 Sulfamethazine 25/185 ... 150 mice from each of the doxylamine, pyrilamine, and triprolidine bioassays a NTP ...
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TR-569: Mixtures of 3'-Azido-3'-Deoxythymidine (AZT), Lamivudine... 7.9MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr569_508.pdf
... - b 4/48 (8.3%) 1/47 (2.1%) 0/48 (0.0%) Pyrilamine - 3/46 (6.5%) 0/47 (0.0%) 0/47 (0.0%) ... 0/44 (0.0%) 1/48 (2.1%) 3/48 (6.3%) Pyrilamine 0/47 (0.0%) 0/47 (0.0%) 1/48 (2.1%) 1/...
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TR 577: Nondecolorized Whole Leaf Extract of Aloe Barbadensis... 11.3MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr577_508.pdf
... Green (June 2001) Diet 0/48 Pyrilamine (July 1991) Diet 0/40 0/44 ... Malachite Green (June 2001) Diet 0/48 Pyrilamine (July 1991) Diet 0/48 0/48 ...
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Public Health Impact 1.5MB
https://ntp.niehs.nih.gov/media/impact
... Technical Report 409. https://ntp.niehs.nih.gov/go/tr409abs Type: Final Rule January 28, 1994 59 FR 4216 469-21-6 91-84-9 1994 FDA Indirect Food Additives: Adjuvants, Production ...