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Search suggestions for "95-53-4".

  1. Report on Carcinogens o-Toluidine hydrochloride https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/toluidine.pdf
  2. CEBS Data Related to 5-Nitro-o-toluidine (99-55-8) https://cebs.niehs.nih.gov/cebs/test_article/99-55-8
  3. CEBS Data Related to Acetyl-o-toluidine (120-66-1) https://cebs.niehs.nih.gov/cebs/test_article/120-66-1
  4. CEBS Data Related to o-Toluidine (95-53-4) https://cebs.niehs.nih.gov/cebs/test_article/95-53-4
  5. Report on Carcinogens 4-Chloro-o-toluidine hydrochloride https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/content/profiles/chlorotoluidine.pdf


127 results found for "95-53-4".

  1. TR-153: o-Toluidine Hydrochloride (CASRN 636-21-5) 2.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr153.pdf

    Series NO. 153 1979 M BIOASSAY OF o-TOLUIDINE HYDROCHLORIDE FOR POSSIBLE ... Institutes of Health BIOASSAY OF o-TOLUIDINE HYDROCHLORIDE FOR POSSIBLE ...

  2. RoC Profile: o-Toluidine; 15th RoC 2021 192KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/toluidine.pdf

    o-Toluidine CAS No. 95-53-4 Known to be a human carcinogen o-Toluidine was first listed in the Third Annual Report on Carcinogens (1982), and its hydrochloride was first listed in ...

  3. RoC Background Document: p-Chloro-o-toluidine and its Hydrochloride... 2.6MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/chloro-o-toluidine_508.pdf

    p-CHLORO-o-TOLUIDINE and ITS HYDROCHLORIDE SALT FINAL MARCH 1999 Prepared for the November ... N01-ES-25346 NTP Report on Carcinogens 1996 Background Document for p-Chloro-o-toluidine ...

  4. TR-107: 5-Nitro-o-toluidine (CASRN 99-55-8) 3.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr107.pdf

    No. 107 1978 BIOASSAY OF 5-NITRO-o-TOLUIDINE FOR POSSIBLE CARCINOGENICITY CAS No. ... of Health :>x; BIOASSAY OF 5-NITRO-o-TOLUIDINE FOR POSSIBLE CARCINOGENICITY ...

  5. TR-165: 4-Chloro-o-toluidine Hydrochloride (CASRN 3165-93-3) 3.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr165.pdf

    OFFICE NO. 165 BIOASSAY OF 4-CHLORO-o-TOLUIDINE HYDROCHLORIDE FOR POSSIBLE ... of Health BIOASSAY OF 4-CHLORO-o-TOLUIDINE HYDROCHLORIDE FOR POSSIBLE ...

  6. TR-187: 5-Chloro-o-toluidine (CASRN 95-79-4) 2.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr187.pdf

    OFFICE No. 187 BIOASSAY OF 5-CHLORO-o-TOLUIDINE FOR POSSIBLE CARCINOGENICITY CAS No. ... of Health BIOASSAY OF 5-CHLORO-o-TOLUIDINE FOR POSSIBLE CARCINOGENICITY ...

  7. RoC Profile: p-Chloro-o-toluidine and Its Hydrochloride; 15th... 142KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/chlorotoluidine.pdf

    p-Chloro-o-toluidine and Its Hydrochloride CAS Nos. 95-69-2 and 3165-93-3 Reasonably ... First listed in the Eighth Report on Carcinogens (1998) Also known as 4-chloro-o-toluidine ...

  8. o-Toluidine hydrochloride: Target Organs and Levels of Evidence... 58KB

    https://ntp.niehs.nih.gov/data/tr/100s/tr153levels

    9 o-Toluidine hydrochloride: Target Organs and Levels of Evidence for TR-153 Bioassay of o-Toluidine Hydrochloride for Possible Carcinogenicity (CASRN 636-21-5) Chemical (Study ...

  9. TOX-44: o-Nitrotoluene (CASRN 88-72-2) ando-Toluidine Hydrochloride... 1.5MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox044.pdf

    Studies of o-Nitrotoluene and o-Toluidine Hydrochloride (CAS Nos. 88-72-2 and ... Studies of o-Nitrotoluene and o-Toluidine Hydrochloride (CAS Nos. 88-72-2 and ...

  10. Abstract for TOX-44 66KB

    https://ntp.niehs.nih.gov/publications/reports/tox/000s/tox044

    of o-Nitrotoluene and o-Toluidine Hydrochloride Administered in Feed to Male F344/N Rats Substances: o-Nitrotoluene (CASRN 88-72-2) o-Toluidine hydrochloride (CASRN ...

  11. RoC Review of o-Toluidine 71KB

    https://ntp.niehs.nih.gov/whatwestudy/assessments/cancer/completed/otoluidine

    5 RoC Review of o-Toluidine Substance Overview CASRN: 95-53-4 Status: RoC: Known to be a human carcinogen Profile: o-Toluidine (192.44 KB) Primary Uses or Exposures An arylamine ...

  12. 5-Nitro-o-toluidine: Target Organs and Levels of Evidence for... 57KB

    https://ntp.niehs.nih.gov/data/tr/100s/tr107levels

    7 5-Nitro-o-toluidine: Target Organs and Levels of Evidence for TR-107 Bioassay of 5-Nitro-o-toluidine for Possible Carcinogenicity (CASRN 99-55-8) Chemical (Study Title) CASRN ...

  13. 4-Chloro-o-toluidine hydrochloride: Target Organs and Levels... 57KB

    https://ntp.niehs.nih.gov/data/tr/100s/tr165levels

    3 4-Chloro-o-toluidine hydrochloride: Target Organs and Levels of Evidence for TR-165 Bioassay of 4-Chloro-o-toluidine Hydrochloride for Possible Carcinogenicity (CASRN 3165-93-3) ...

  14. 5-Chloro-o-toluidine: Target Organs and Levels of Evidence for... 57KB

    https://ntp.niehs.nih.gov/data/tr/100s/tr187levels

    7 5-Chloro-o-toluidine: Target Organs and Levels of Evidence for TR-187 Bioassay of 5-Chloro-o-toluidine for Possible Carcinogenicity (CASRN 95-79-4) Chemical (Study Title) CASRN ...

  15. Use of Toluidine in the Manufacture of Dyes 253KB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/protocols/otolconsultant_report_508.pdf

    Integrated Laboratory Systems, Inc. Use of o-Toluidine in the Manufacture of Dyes and on the Potential for Exposure to other Chemicals in the Processes involving o-Toluidine Prof. ...

  16. Abstract for TR-153 62KB

    https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr153

    3abs Abstract for TR-153 Bioassay of o-Toluidine Hydrochloride for Possible ... Full Report PDF Abstract o-Toluidine and its hydrochloride salt are dye intermediates used ...

  17. Abstract for TR-187 63KB

    https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr187

    Abstract for TR-187 Bioassay of 5-Chloro-o-toluidine for Possible Carcinogenicity CASRN: ... Full Report PDF Abstract 5-Chloro-o-toluidine, an aromatic amine and dye intermediate, was ...

  18. Abstract for TR-107 62KB

    https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr107

    Abstract for TR-107 Bioassay of 5-Nitro-o-toluidine for Possible Carcinogenicity CASRN: ... Full Report PDF Abstract 5-Nitro-o-toluidine, an intermediate in the synthesis of azo ...

  19. Abstract for TR-165 62KB

    https://ntp.niehs.nih.gov/publications/reports/tr/100s/tr165

    Abstract for TR-165 Bioassay of 4-Chloro-o-toluidine Hydrochloride for Possible ... Full Report PDF Abstract 4-Chloro-o-toluidine hydrochloride is used commercially as an ...

  20. Peer Review Report: RoC Peer Review; Dec. 12-13, 2013 287KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2013/december/peerreviewrpt20131213_508.pdf

    ... for o- toluidine and pentachlorophenol. In January 2012, a Federal Register notice was published inviting public comment on 20 nominations, including o-toluidine and ...

  21. Draft RoC Monograph for ortho-Toluidine: Literature Search Strategy... 1.1MB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/litsearchstrategy/otol_literaturesearch20130815_508.pdf

    used to identify literature for the draft monograph on ortho-toluidine (CASRN 95-53-4). ... o-nitrosotoluene, N-acetyl-o-toluidine, N-acetyl-o-aminobenzyl alcohol, ...

  22. RoC Monograph: ortho-Toluidine; July 2014 2.4MB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/monographs_final/otoluidine_508.pdf

    ... of evidence for the carcinogenicity of o-toluidine from studies in experimental animals ... (ortho-methylaniline, CASRN 95-53-4) is a synthetic chemical that is ...

  23. Minutes: BSC RoC; Nov. 18-19, 1996 149KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1996/dec/brc_minutes19961119_508.pdf

    A Thiotepa Azactidine p-Chloro-o-toluidine and its hydrochloride salt ... The motion was seconded and accepted unanimously with five votes. p-Chloro-o-toluidine and ...

  24. Background Document: RoC: o-Nitrotoluene ; 2010 1.5MB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/o-nt-final_508.pdf

    ... exposed to other chemicals, such as o-toluidine, 2,5-diaminotoluene, and ... workers exposed to dinitrotoluenes or o-toluidine ...... 21 ...

  25. Minutes: BSC; April 17-18, 2014 253KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2014/april/minutes20140418_508.pdf

    (ORoC) Peer-Review Meeting on o-Toluidine and Pentachlorophenol (PCP) and ... VI. Office of the Report on Carcinogens (ORoC) Peer-Review Meeting on o- Toluidine and ...

  26. Appendix G; 15th RoC 2021 73KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_g.pdf

    ... Benzidine 93-15-2 see Methyleugenol 94-59-7 see Safrole 95-06-7 see Sulfallate 95-53-4 (o-toluidine) see o-Toluidine and Its Hydrochloride 95-69-2 (p-chloro-o-toluidine) see ...

  27. Completed RoC Evaluations 119KB

    https://ntp.niehs.nih.gov/whatwestudy/assessments/cancer/completed/roc

    ... Background Document Request Archived Materials p-Chloro-o-toluidine and its Hydrochloride ... Appendix A Appendix B Request Archived Materials o-Toluidine Known to be a human ...

  28. 15th RoC: Appendix F 174KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendix_f.pdf

    ... 4-chloro-2-methylaniline see p-Chloro-o-toluidine and Its Hydrochloride 4-chloro-2-methylbenzenamine see p-Chloro-o-toluidine and Its Hydrochloride 4-chloro-2-methylbenzena...

  29. Listed Substances; 15th RoC 2021 76KB

    https://ntp.niehs.nih.gov/ntp/roc/content/listed_substances_508.pdf

    ... (see Tobacco-Related Exposures) o-Toluidine Trichloroethylene Ultraviolet ... Chloroprene p-Chloro-o-toluidine and Its Hydrochloride Chlorozotocin ...

  30. Captafol/o-Nitrotoluene Expert Panel Report Part A - Peer Review... 138KB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2007/expertpanelmtgs/o_nitrotolouene_reportparta_508.pdf

    ... although also exposed to o-toluidine and 4,4'- methylene ... by the expert panel) 4. Section 5.5.3 o-Toluidine hydrochloride 2 Note: Section number, ...

  31. Comment: Meat-related exposures; Robert Turesky, University of... 4.6MB

    https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/turesky20161005.pdf

    ... μg/L, and the urinary levels of o-toluidine reached up to 132 μg/L from workers, ... respectively, whereas the amounts of o-toluidine range from 9 to 144 ng per cigarette. ...

  32. Captafol/o-Nitrotoluene Expert Panel Report Part B; RoC; Oct... 169KB

    https://ntp.niehs.nih.gov/ntp/roc/twelfth/2007/expertpanelmtgs/o_nitrotolouene_reportpartb_508.pdf

    ... this subgroup was also exposed to o-toluidine and 4,4'-methylene bis(2- methylaniline). ... Two studies that involved o-toluidine exposure reported excess bladder cancer incidence. ...

  33. RoC Profile: o-Nitrotoluene; 15th RoC 2021 162KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/nitrotoluene.pdf

    ... were also exposed to other chemicals - o-toluidine (2-methylani- line) and ... Use o-Nitrotoluene is used primarily in the production of o-toluidine (also known as ...

  34. Monographs 71KB

    https://ntp.niehs.nih.gov/publications/monographs

    and By-Products of Its Synthesis (PCP) Monograph (Abstract) RoC 2014 o-Toluidine Monograph (Abstract) RoC 2014 Cumene Monograph (Abstract) RoC 2013 Cancer ...

  35. Agenda: Peer Review of Draft RoC Monographs on ortho-Toluidine... 166KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/monopeerrvw/2013/december/agenda20131212_508.pdf

    The chair will set time for breaks and lunch. Agenda - Draft Report on Carcinogens Monographs for o-Toluidine and Pentachlorophenol Peer Review December 12-13, 2013 D. Disposition ...

  36. Spleen - Adipocyte Metaplasia - Nonneoplastic Lesion Atlas 288KB

    https://ntp.niehs.nih.gov/atlas/nnl/immune-system/spleen/AdipocyteMetaplasia

    Goodman DG, Ward JM, Reichardt WD. 1984. Splenic fibrosis and sarcomas in F344 rats fed diets containing aniline hydrochloride, p-chloroaniline, azobenzene, o-toluidine ...

  37. Spleen - Hemorrhage - Nonneoplastic Lesion Atlas 288KB

    https://ntp.niehs.nih.gov/atlas/nnl/immune-system/spleen/Hemorrhage

    References: National Cancer Institute. 1979. NCI-CG-TR-153. Bioassay of o-Toluidine Hydrochloride for Possible Carcinogenicity (CAS No. 636-21-5) in F344/N Rats and B6C3F1 Mice ...

  38. Spleen - Hemorrhage 290KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/immune/spleen/hemorr/spleen-hemorrhage-pdf_508.pdf

    References: National Cancer Institute. 1979. NCI-CG-TR-153. Bioassay of o-Toluidine Hydrochloride for Possible Carcinogenicity (CAS No. 636-21-5) in F344/N Rats and B6C3F1 Mice ...

  39. RoC Concept: ortho-Toluidine 318KB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/concepts/otolconcdocroc8-30-12_508.pdf

    1. Rationale ortho-Toluidine (CASRN 95-53-4) is an arylamine used (either directly or ... bladder cancer risk among workers exposed to o-toluidine and aniline: a reanalysis. ...

  40. Spleen - Adipocyte Metaplasia 314KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/immune/spleen/admetap/spleen-adipocyte-metaplasia-pdf_508.pdf

    F344 rats fed diets containing aniline hydrochloride, p-chloroaniline, azobenzene, o-toluidine hydrochloride, 4,4'- sulfonyldianiline, or D&C red no. 9. J Natl Cancer Inst ...

  41. Protocol: Evaluation of Human Cancer Studies on Exposure to ortho... 518KB

    https://ntp.niehs.nih.gov/ntp/roc/thirteenth/protocols/ortho-toluidineprotocol_508.pdf

    information ortho---Toluidine (CASRN 95---53---4) is an arylamine used (either directly ... chemicals OR ortho toluidine OR o---toluidine OR chloro---o--- toluidine OR ...

  42. RoC Profile: Basic Red 9 Monohydrochloride; 15th RoC 2021 121KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/basicred9.pdf

    increased incidence of cancer in magenta workers was attributable to exposure to magenta or to one or more of its interme- diates and impurities, such as o-toluidine or aniline. ...

  43. Agenda: BSC; Apr. 14, 2016 94KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/2014/april/agenda20140416_508.pdf

    Birnbaum Dr. Peterson 2:15 Office of Report on Carcinogens (ORoC) Peer- Review Meeting on o-Toluidine and Pentachlorophenol and By-products of its Synthesis . Public Comments . BSC ...

  44. TR-504: o-Nitrotoluene (CASRN 88-72-2) in F344/N Rats and B6C3F1... 14.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr504.pdf

    ... not identified by Chism et al. (1984). o-Toluidine was also identified as a minor ... The National Cancer Institute (1979) reported that o-toluidine hydrochloride was ...

  45. Spleen - Fibrosis - Nonneoplastic Lesion Atlas 292KB

    https://ntp.niehs.nih.gov/atlas/nnl/immune-system/spleen/Fibrosis

    Goodman DG, Ward JM, Reichardt WD. 1984. Splenic fibrosis and sarcomas in F344 rats fed diets containing aniline hydrochloride, p-chloroaniline, azobenzene, o-toluidine ...

  46. Spleen - Fibrosis 442KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/immune/spleen/fibrosis/spleen-fibrosis-pdf_508.pdf

    ... References: Goodman DG, Ward JM, Reichardt WD. 1984. Splenic fibrosis and sarcomas in F344 rats fed diets containing aniline hydrochloride, p-chloroaniline, azobenzene, o-toluidine ...

  47. RoC Profile: 3,3'-Dichlorobenzidine and Its Dihydrochloride;... 146KB

    https://ntp.niehs.nih.gov/ntp/roc/content/profiles/dichlorobenzidine.pdf

    ... to 3,3'-dichloro benzidine; however, the workers potentially were also exposed to other substances associated with uri- nary-bladder cancer, such as o-toluidine or benzidine. ...

  48. TOX-23: o-,m-, and p- Nitrotoluenes (CASRNs 88-72-2, 99-08-1... 15.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox023.pdf

    ... The NCI has reported that o-toluidine was positive in 2-year studies in male rats ... Chronic exposure of rats to this group of chemicals, which includes o-toluidine, has ...

  49. TOX-43: o-,m-, and p-Chloroanilines (CASRNs 95-51-2; 108-42-9... 5.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox043.pdf

    ... Azobenzene, D & C Red No. 9, dapsone, and o-toluidine hydrochloride, all structurally ... (Ward et al., 1980; Chhabra, 1990). o-Toluidine hydrochloride and azobenzene, compounds ...

  50. Appendices A-G; 15th RoC 2021 448KB

    https://ntp.niehs.nih.gov/ntp/roc/content/appendices_508.pdf

    ... 4-chloro-2-methylaniline see p-Chloro-o-toluidine and Its Hydrochloride 4-chloro-2-methylbenzenamine see p-Chloro-o-toluidine and Its Hydrochloride 4-chloro-2-methylbenzena...

 
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