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RoC Background Document: Nickel Compounds; Dec. 2-3, 1998 6.7MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/nickelcompds1_oneapp_508.pdf
NICKEL COMPOUNDS FINAL MARCH 1999 Prepared for the December 2-3, 1998, Meeting of the Report on Carcinogens Subcommittee of the NTP Board of Scientific Counselors Prepared by ...
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RoC Profile: Nickel Compounds and Metallic Nickel; 15th RoC 2021 170KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/nickel.pdf
Nickel Compounds and Metallic Nickel Introduction Nickel compounds and metallic nickel have many industrial and com- mercial applications, including use in stainless steel and ...
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Minutes: BSC TRRS; May 21, 1999 160KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1999/may/trrs21may1999mins_508.pdf
National Toxicology Program Board of Scientific Counselors Summary Minutes from Peer Review of Draft Technical Reports of Long-Term Toxicology and Carcinogenesis Studies by the ...
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Background Document: Styrene oxide; BSC RoC, Jan. 20-21, 2000 267KB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/bg_styrene_oxide_508.pdf
FINAL Report on Carcinogens Background Document for Styrene-7,8-oxide Meeting of the NTP Board of Scientific Counselors Report on Carcinogens Subcommittee Prepared for the: U.S. ...
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Background Document: RoC: Glass Wool Fibers; 2010 3.7MB
https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/glasswoolbd20100408_508.pdf
Report on Carcinogens Background Document for Glass Wool Fibers September 2009 National Toxicology Program U.S. Department of Health and Human Services Public Health Service ...
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TR592: Dietary Zinc (CASRN 5263-02-5) In Sprague Dawley Rats... 2.0MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr592_508.pdf
oN The Toxicology aNd caRciNogeNesis sTudy of dieTaRy ZiNc (casRN 5263-02-5) iN sPRague dawley (hsd:sPRague dawley ® sd ® ) RaTs (feed sTudy) NTP TR 592 JANUARY 2019 NTP ...
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Draft RoC Monograph for Pentachlorophenol: Literature Search... 2.0MB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/litsearchstrategy/pcpliteraturesearch20130815_508.pdf
... induces the formation of 8-hydroxy-2-
deoxyguanosine in liver DNA of male B6C3F 1 mice. ... KE. 1995. Induction of 8-hydroxy-2-deoxyguanosine and single-strand breaks in DNA of ...
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Minutes: BSC RoC; Nov. 11, 2008 624KB
https://ntp.niehs.nih.gov/sites/default/files/ntp/roc/twelfth/draftbackgrounddocs/roc_minutes20021120.pdf
National Toxicology Program Board of Scientific Counselors Report on Carcinogens Subcommittee Meeting November 19-20, 2002 Hyatt Regency Bethesda, Bethesda, Maryland Summary ...
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TR-459: t-Butylhydroquinone (CASRN 1948-33-0) in F344 Rats and... 25.3MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr459.pdf
NATIIONAL T O X I I C O L O G ~ PII~OGII~L~]~'iI T e c ~ e ~ ~ o ~ ~erb~ , Ne. 459 ~ST-~VICI~$04 " T © X J I C © L © G Y ANII> CAXCIIN©GENIZSff$ $ T ~ f f E 5 ©~ ...
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TOX-87: Fullerene C60 (1 μm and 50 nm) (CASRN 99685-96-8) Administere... 3.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox087_508.pdf
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TR-453: Nickel Subsulfide (CASRN 12035-72-2) in F344 Rats and... 17.9MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr453.pdf
3 TOXICOLOGY AND CARCINOGENESIS STUDIES OF NICKEL SUBSULFIDE (CAS NO. 12035-72-2) IN F344/N RATS AND B6C3Fl M I C E (INHALATION STUDIES) U . S . DEPARTMENT OF HEALTH ...
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TR-454: Nickel Sulfate Hexahydrate (CASRN 10101-97-0) in F344... 19.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr454.pdf
NATIONALTOXICOLOGY PROGRAM Technical Report Series No. 454 TOXICOLOGY AND CARCINOGENESIS STUDIES OF NICKEL SULFATE HEXAHYDRATE (CAS NO. 10101-97-0) IN F344/N RATS AND B6C3F, MICE ...
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TR-451: Nickel Oxide (CASRN 1313-99-1) in F344 Rats and B6C3F1... 27.7MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr451.pdf
1 .~, ~t~vn(/:s e,~ °~22Z'~-~ T O X I C O L O G Y A N D C A R C I N O G E N E S I S S T U D I E S O F N I C K E L O X I D E (CAS NO. 1313-99-1) IN F344/N R A T S A N D B6C3F 1 M I ...
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RoC Background Document: 1-Nitropyrene; Nov. 18-19, 1996 4.3MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/nitropyrene-1_508.pdf
... In addition to the formation of this DNA adduct, two N 2
-deoxyguanosine adducts, ... In addition to the formation ofXVI, two N 2
-deoxyguanosine adducts, 6-(deoxyguanosin-N 2 ...
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Public Comment: Ruth Danzeisen of Cobalt Development Institute... 1.1MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/publiccomm/cdi20150708.pdf
the Cobalt Development Institute 8 July 2015 18 Jeffries Passage, Guildford, Surrey, GU1 4AP, United Kingdom Tel: +44 1483 578877 e-mail: info@thecdi.com Fax: +44 1483 567042 ...
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TR-583: Bromodichloroacetic Acid (CASRN 71133-14-7) in F344/N... 4.7MB
https://ntp.niehs.nih.gov/go/tr583
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Styrene Expert Panel Report Part A; RoC; July 21-22, 2008 756KB
https://ntp.niehs.nih.gov/ntp/roc/twelfth/2008/expertpanelmtgs/styrene_panelreportparta_508.pdf
Styrene Expert Panel Report Part A - Peer Review of the draft background document on styrene The Report on Carcinogens (RoC) expert panel for styrene met at the Radisson Hotel, ...
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TR-483: Pentachlorophenol (CASRN 87-86-5) in F344/N Rats (Feed... 7.7MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr483.pdf
... induces the formation of 8-hydroxy-2-
deoxyguanosine in liver DNA of male B6C3F1 mice. ... Induction of 8-hydroxy-2-deoxyguanosine and single-strand breaks in DNA of V79 cells by ...
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RoC Background Document: Ultraviolet (UV) Radiation, Broad Spectrum... 3.0MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc10/uv_no_appendices_508.pdf
Broad-Spectrum Ultraviolet (UV) Radiation and UVA, and UVB, and UVC December 13-14, 2000 Meeting of the NTP Board of Scientific Counselors Report on Carcinogens Subcommittee ...
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RoC Profile: Cobalt-Related Exposures; 15th RoC 2021 409KB
https://ntp.niehs.nih.gov/ntp/roc/content/profiles/cobalt.pdf
Genomic stability Oxidative damage Hypoxia-responsive target genes Resistance to apoptosis Accumulation of critical mutations Dysregulation of cell growth and proliferation Tumor ...
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RoC Monograph: 1-Bromopropane; September 2013 1.9MB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/monographs_final/1bromopropane_508.pdf
1-BRoMopRopane ROC MONOGRAPH 01 SEPTEMBER 2013 Report on Carcinogens Monograph on 1-Bromopropane RoC Monograph 01 September 2013 National Toxicology Program Public Health Service ...
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Background Document: RoC: Riddelliine; 2010 1.7MB
https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/riddelliine_final_508.pdf
Riddelliine August 11, 2008 U.S. Department of Health and Human Services Public Health Services National Toxicology Program Research Triangle Park, NC 27709 This Page Intentionally ...
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RoC Background Document: Tobacco Smoking; Dec. 2-3, 1998 3.5MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/environmentalts_noapps_508.pdf
Environmental Tobacco Smoke December 2 - 3, 1998 Meeting of the NTP Board of Scientific Counselors Report on Carcinogens Subcommittee Prepared for the: U.S. Department of Health ...
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TR-509: 2,4-Hexadienal (89% trans,trans Isomer, CASRN 142-83... 10.5MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr509.pdf
... Cancer Res. 46, 5029-5034. Dahlhaus, M., Almstadt, E., Henschke, P., Luttgert, S., and Appel, K.E. (1995). Induction of 8-hydroxy-2-
deoxyguanosine and single-strand breaks in DNA ...
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TR-593: NTP Technical Report on the Toxicology and Carcinogenesis... 7.2MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr593_508.pdf
... shown to form adducts with 2-deoxyguanosine and to disrupt DNA ternary structure 151 . ... forms a covalent adduct with 2-
deoxyguanosine, uncoils DNA, and leads to cell death. ...
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RoC Monograph: Pentachlorophenol and By-products of Its Synthesis... 2.9MB
https://ntp.niehs.nih.gov/ntp/roc/thirteenth/monographs_final/pentachlorophenol_508.pdf
... induces the formation of 8-hydroxy-2-deoxyguanosine in liver DNA of male B6C3F1 mice. ... KE. 1995. Induction of 8-hydroxy-2-
deoxyguanosine and single-strand breaks in DNA of ...
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Comment: Meat-related exposures; Robert Turesky, University of... 4.6MB
https://ntp.niehs.nih.gov/ntp/roc/nominations/2016/publiccomm/turesky20161005.pdf
... Soc. 126, 11189-11201. (488) Stover, J. S., and Rizzo, C. J. (2007) Synthesis of oligonucleo- tides containing the N 2
-deoxyguanosine adduct of the dietary carcino- gen ...
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TR-588: Glycidamide (CASRN 5694-00-8) in F344/N Nctr Rats and... 3.6MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr588_508.pdf
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TR-598: Perfluorooctanoic Acid (CASRN 335-67-1) Administered... 5.5MB
https://ntp.niehs.nih.gov/ntp/htdocs/lt_rpts/tr598_508.pdf
PeRfluoRoocTaNoic acid (casRN 335-67-1) admiNisTeRed iN feed To sPRague dawley (hsd:sPRague dawley ® sd ® ) RaTs (Revised) NTP TR 598 MAY 2020 REVISED FEBRUARY 2023 NTP Technical ...
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Draft TR-598: Perfluorooctanoic Acid (CASRN 335-67-1) Administered... 5.1MB
https://ntp.niehs.nih.gov/ntp/about_ntp/trpanel/2019/december/tr598draft.pdf
NTP Technical Report on the Toxicology and Carcinogenesis Studies of Perfluorooctanoic Acid (CAS No. 335-67-1) Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley ® SD ® ...
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Background Document: RoC: Cobalt-Tungsten Carbide: Powders and... 1.9MB
https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/hardmetalsbd20100408_508.pdf
Report on Carcinogens Background Document for Cobalt-Tungsten Carbide: Powders and Hard Metals March 2009 National Toxicology Program U.S. Department of Health and Human Services ...
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TOX-97: Toxicity Studies of Perfluoroalkyl Carboxylates (Perfluorohexa... 8.6MB
https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox097_508.pdf
caRboxylaTeS (PeRfluoRohexaNoic acid, PeRfluoRoocTaNoic acid, PeRfluoRoNoNaNoic acid, aNd PeRfluoRodecaNoic acid) admiNiSTeRed by GavaGe To SPRaGue dawley (hSd:SPRaGue dawley Sd) ...
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RoC Monograph: Cobalt and Cobalt Compounds; April 2016 3.5MB
https://ntp.niehs.nih.gov/ntp/roc/monographs/cobalt_final_508.pdf
Cobalt and Cobalt CoMpounds that Release Cobalt ions in ViVo ROC MONOGRAPH 06 APRIL 2016 Report on Carcinogens Monograph on Cobalt and Cobalt Compounds That Release Cobalt Ions In ...
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Background Document for Selected Heterocyclic Amines: PhIP, MeIQ... 3.3MB
https://ntp.niehs.nih.gov/ntp/newhomeroc/roc11/hcaspub_508.pdf
FINAL Report on Carcinogens Background Document for Selected Heterocyclic Amines: PhIP, MeIQ, and MeIQx September 19, 2002 Prepared for the: U.S. Department of Health and Human ...
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Draft RoC Monograph Cobalt: RoC Peer Review; July 22, 2015 2.8MB
https://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_draftmonograph.pdf
Cobalt and Certain Cobalt Compounds June 5, 2015 Office of the Report on Carcinogens Division of the National Toxicology Program National Institute of Environmental Health ...
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RoC Monograph: Trichloroethylene; January 2015 4.6MB
https://ntp.niehs.nih.gov/ntp/roc/monographs/finaltce_508.pdf
RepoRt on CaRCinogens MonogRaph on tRiChloRoethylene ROC MONOGRAPH 05 JANUARY 2015 Report on Carcinogens Monograph on Trichloroethylene RoC Monograph 05 January 2015 National ...
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Revised Draft RoC Monograph Cobalt: RoC Peer Review; July 22... 3.0MB
https://ntp.niehs.nih.gov/ntp/roc/draftmono/revised_cobalt.pdf
Monograph on Cobalt and Cobalt Compounds That Release Cobalt Ions In Vivo November 6, 2015 Office of the Report on Carcinogens Division of the National Toxicology Program National ...
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Background Document: RoC: Styrene; 2010 4.3MB
https://ntp.niehs.nih.gov/ntp/roc/twelfth/2010/finalbds/styrene_final_508.pdf
FINAL Report on Carcinogens Background Document for Styrene September 29, 2008 U.S. Department of Health and Human Services Public Health Servces National Toxicology Program ...