Skip to Main Navigation Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

We welcome your feedback!

Contact us with your comments.

QUICK TIPS
 
of 3

Refine

  • Categories
  • Content Type
  • Reports and Publications
  • Years
  • Formats

Search suggestions for "98-01-1".

  1. CEBS Data Related to Furfural (98-01-1) https://cebs.niehs.nih.gov/cebs/test_article/98-01-1


138 results found for "98-01-1".

  1. TR-382: Furfural (CASRN 98-01-1) in F344/N Rats and B6C3F1Mice... 11.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr382.pdf

    3 TOXICOLOGY AND CARCINOGENESIS STUDIES OF FURFURAL (CAS NO. 98-01-1) IN F344/N RATS AND B6C3F1 MICE (GAVAGE STUDIES) U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health ...

  2. TR-554: 5-(Hydroxymethyl)-2-furfural (CASRN 67-47-0) in F344... 7.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr554.pdf

    5-(HYDROXYMETHYL)-2-FURFURAL (CAS NO. 67-47-0) IN F344/N RATS AND B6C3F1 MICE (GAVAGE ... TOXICOLOGY AND CARCINOGENESIS STUDIES OF 5-(HYDROXYMETHYL)-2-FURFURAL (CAS NO. 67-47-0) IN ...

  3. TR-482: Furfural Alcohol (CASRN 98-00-0) in F344/N Rats and B6C3F1... 27.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr482.pdf

    ... as part of a class study with furan and furfural, noting that cholangiocarcinomas and other hepatocellular neoplasms were significant neoplastic findings with furan and furfural. ...

  4. Abstract for TR-554 72KB

    https://ntp.niehs.nih.gov/publications/reports/tr/500s/tr554

    Toxicology and Carcinogenesis Studies of 5-(Hydroxymethyl)-2-Furfural in F344/N Rats and ... Full Report PDF Abstract 5-(Hydroxymethyl)-2-furfural is formed when reducing sugars such ...

  5. Abstract for TR-382 65KB

    https://ntp.niehs.nih.gov/publications/reports/tr/300s/tr382

    Abstract for TR-382 Toxicology and Carcinogenesis Studies of Furfural in F344/N Rats and B6C3F1 Mice (Gavage Studies) CASRN: 98-01-1 Chemical Formula: C5H4O2 Molecular Weight: 96.1 ...

  6. Target Organs and Levels of Evidence for TR-382 58KB

    https://ntp.niehs.nih.gov/data/tr/300s/tr382levels

    Target Organs and Levels of Evidence for TR-382 Toxicology and Carcinogenesis Studies of Furfural (CASRN 98-01-1) in F344/N Rats and B6C3F1 Mice (Gavage Studies) Chemical (Study ...

  7. Target Organs and Levels of Evidence for TR-554 60KB

    https://ntp.niehs.nih.gov/data/tr/500s/tr554levels

    Toxicology and Carcinogenesis Studies of 5-(Hydroxymethyl)-2-furfural (CASRN 67-47-0) in ... Study Laboratory 5-(Hydroxymethyl)-2-furfural 67-47-0 02/27/2008 Gavage R&M: 0, 188, ...

  8. Target Organs and Levels of Evidence for TR-482 60KB

    https://ntp.niehs.nih.gov/data/tr/400s/tr482levels

    Target Organs and Levels of Evidence for TR-482 Toxicology and Carcinogenesis Studies of Furfural Alcohol (CASRN 98-00-0) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) ...

  9. Minutes: BSC TRRS; Feb. 27, 2008 112KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2008/feb/trrs27feb2008mins_508.pdf

    12 5-(Hydroxymethyl)-2-furfural ......carried with 8 yes votes, 0 no vote, and 0 abstentions. 5-(HYDROXYMETHYL)-2-FURFURAL Dr. ...

  10. Historical Controls: Pathology Tables by Gavage/Water for B6C3F1... 85KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/mice_gavh2o_path_hist09.pdf

    50 (1) 40(702) 52.3 5-(Hydroxymethyl)-2-furfural Female Battelle Columbus Laboratory ... 50 (5) 39(694) 64.4 5-(Hydroxymethyl)-2-furfural Version: May2009 Toxicology Data ...

  11. Historical Controls: Pathology Tables by Gavage/Water for Fischer... 85KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/rats_gavh2o_path_hist09.pdf

    50 (3) 22(673) 510.3 5-(Hydroxymethyl)-2-furfural Female Battelle Columbus Laboratory ... 50 (5) 31(679) 332.2 5-(Hydroxymethyl)-2-furfural Version: May2009 Toxicology Data ...

  12. Historical Controls: Chemicals by Species/Route/Vehicle for Fischer... 206KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009_byroute.pdf

    Mice Gavage Water 5-(Hydroxymethyl) -2-furfural Mice Inhalation Air 1-Bromopropane Mice ... Rats Gavage Water 5-(Hydroxymethyl) -2-furfural Rats Inhalation Air 1-Bromopropane Rats ...

  13. Historical Controls: Pathology Tables by Gavage/Water for B6C3F1... 139KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/gavwatermice2010mar.pdf

    50(1) 40(702) 52.3 5-(Hydroxymethyl)-2-furfural Female Battelle Columbus Laboratory ... 50(5) 39(694) 64.4 5-(Hydroxymethyl)-2-furfural NOTE: The text on page 2 ("Report ...

  14. Historical Controls: Pathology Tables by Gavage/Water for Fischer... 139KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/gavwaterrats2010mar.pdf

    50(3) 22(673) 510.3 5-(Hydroxymethyl)-2-furfural Female Battelle Columbus Laboratory ... 50(5) 31(679) 332.2 5-(Hydroxymethyl)-2-furfural NOTE: The text on page 2 ("Report ...

  15. Historical Controls: Pathology Tables by Gavage/Water for Fischer... 135KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/ratsgavwater.pdf

    50(3) 22(673) 510.3 5-(Hydroxymethyl)-2-furfural Female Battelle Columbus Laboratory ... 50(5) 31(679) 332.2 5-(Hydroxymethyl)-2-furfural NOTE: The text on page 2 ("Report ...

  16. Historical Controls: Chemicals by Sex/Species/Route/Vehicle for... 14KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/histcont_2010_studies.pdf

    Female Gavage Water 5-(Hydroxymethyl)-2-furfural Mice B6C3F1 Male and Female Inhalation ... Female Gavage Water 5-(Hydroxymethyl)-2-furfural Rats F 344/N Male and Female Inhalation ...

  17. TR-402: Furan (CASRN 110-00-9) in F344 Rats and B6C3F1 Mice(Gavage... 31.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr402.pdf

    ... Commercial production of furan is performed by the decarbonylation of furfural, which can be accom- plished by a number of processes. Steam distillation of furfural over catalysts ...

  18. Nose - Polyp, Inflammatory - Nonneoplastic Lesion Atlas 288KB

    https://ntp.niehs.nih.gov/atlas/nnl/respiratory-system/nose/PolypInflammatory

    National Toxicology Program. 2010. NTP TR-554. Toxicology and Carcinogenesis Studies of 5-(Hydroxymethyl)-2-furfural (CAS No. 67-47-0) in F344/N Rats and B6C3F1 Mice (Gavage ...

  19. Historical Controls: All Routes and Vehicles for Mice; Studies... 211KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/m_hcrpt_allrte20071000_508.pdf

    ... 50(1) 40(702) 52.3 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810504 ... 50(5) 39(694) 64.4 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810504 ...

  20. Historical Controls: All Routes and Vehicles for Rats; Studies... 252KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/r_hcrpt_allrte20070300_508.pdf

    ... 50(3) 22(673) 510.3 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810503 ... 50(5) 31(679) 332.2 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810503 ...

  21. Historical Controls: All Routes and Vehicles for Rats; Studies... 225KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/r_hcrpt_allrte20071000_508.pdf

    ... 50(3) 22(673) 510.3 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810503 ... 50(5) 31(679) 332.2 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810503 ...

  22. Historical Controls: All Route and Vehicles for Rats; Studies... 162KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2008/r_hcrtp_allrte_20081100.pdf

    ... 50 (3) 22(673) 510.3 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810503 ... 50 (5) 31(679) 332.2 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810503 ...

  23. Nose - Polyp, Inflammatory 270KB

    https://ntp.niehs.nih.gov/sites/default/files/nnl/respiratory/nose/polyp/nose-polyp-inflammatory-pdf_508.pdf

    Toxicology Program. 2010. NTP TR-554. Toxicology and Carcinogenesis Studies of 5- (Hydroxymethyl)-2-furfural (CAS No. 67-47-0) in F344/N Rats and B6C3F1 Mice (Gavage Studies). ...

  24. Agenda: BSC TRRS; Feb. 27-28, 2008 36KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/2008/feb/trrs27feb2008agendafnl_508.pdf

    John Peckham Dr. Kenny Crump Dr. Michael Pino Dr. Christopher Bradfield 5-(Hydroxymethyl)-2- furfural (67-47-0) TR 554 Gavage Male and female F-344/N rats and B6C3F1 mice Dr. ...

  25. Historical Controls: All Routes and Vehicles for Mice; Studies... 317KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2007/m_hcrpt_allrte20070300_508.pdf

    ... 50(1) 40(702) 52.3 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810504 ... 50(5) 39(694) 64.4 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810504 ...

  26. Historical Controls: Pathology Tables for All Routes/Vehicles... 176KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009-05-14-hist-miceallroutes.pdf

    ... 50 (1) 40(702) 52.3 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810504 ... 50 (5) 39(694) 64.4 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810504 ...

  27. Historical Controls: Pathology Tables for All Routes/Vehicles... 174KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2009/2009-05-14-hist-ratsallroutes.pdf

    ... 50 (3) 22(673) 510.3 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810503 ... 50 (5) 31(679) 332.2 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810503 ...

  28. Historical Controls: Pathology Tables for All Routes/Vehicles... 307KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/2010-03-22-hist-miceallroutes.pdf

    ... 50(1) 40(702) 52.3 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810504 ... 50(5) 39(694) 64.4 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810504 ...

  29. Historical Controls: Pathology Tables for All Routes/Vehicles... 309KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2010/2010-03-22-hist-ratsallroutes.pdf

    ... 50(3) 22(673) 510.3 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810503 ... 50(5) 31(679) 332.2 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810503 ...

  30. Historical Controls: Pathology Tables All Routes/Vehicles for... 309KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont2011_rats_allroutes.pdf

    ... 50(3) 22(673) 510.3 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810503 ... 50(5) 31(679) 332.2 5-(Hydroxymethyl)-2-furfural Battelle Columbus Laboratory 058810503 ...

  31. Historical Controls: Chemicals by Sex/Species/Route/Vehicle for... 83KB

    https://ntp.niehs.nih.gov/ntp/historical_controls/ntp2000_2011/histcont_2011_studies.pdf

    Gavage Water Ginseng Rats F 344/N Male and Female Gavage Water 5-(Hydroxymethyl)-2-furfural Rats F 344/N Male and Female Inhalation Air 1-Bromopropane Rats F 344/N Male and ...

  32. NTP Technical Reports Index 1.5MB

    https://ntp.niehs.nih.gov/data/tr

    ... TR-554 02/28/08 5-(Hydroxymethyl)-2-Furfural 67-47-0 NE No Evidence NE No Evidence NE ... P Clear Evidence TR-382 11/20/89 Furfural 98-01-1 SE Some Evidence NE No Evidence ...

  33. Technical Reports 903KB

    https://ntp.niehs.nih.gov/publications/reports/tr

    ... Studies of 5-(Hydroxymethyl)-2-furfural (CASRN 67-47-0) in F344/N Rats and ... Toxicology and Carcinogenesis Studies of Furfural Alcohol in F344/N Rats and B6C3F1 Mice ...

  34. RoC Background Document: 1,3-Butadiene; Oct. 30-31, 1997 9.0MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/butadiene_508.pdf

    ... norbornene, butadiene-furfural cotrimer, sulfolane, and 1,3-butadiene cylinders. ... In the extraction plants, solvents such as dimethylformamide, acetonitrile, furfural, ...

  35. RoC Background Document: Furan; Nov. 18-19, 1996 3.0MB

    https://ntp.niehs.nih.gov/ntp/newhomeroc/other_background/furan1_508.pdf

    ... Commercial production of furan involves decarbonylation of furfural over a palladium/... .This table could include studies on furfural, tetrahydrofuran, o-anisidine, other ...

  36. Study Reports 1.1MB

    https://ntp.niehs.nih.gov/publications/reports

    ... Studies of 5-(Hydroxymethyl)-2-furfural (CASRN 67-47-0) in F344/N Rats and ... Toxicology and Carcinogenesis Studies of Furfural Alcohol in F344/N Rats and B6C3F1 Mice ...

  37. Toxicology/Carcinogenicity 1.1MB

    https://ntp.niehs.nih.gov/whatwestudy/testpgm/cartox

    ... Studies of 5-(Hydroxymethyl)-2-furfural (CASRN 67-47-0) in F344/N Rats and ... Toxicology and Carcinogenesis Studies of Furfural Alcohol in F344/N Rats and B6C3F1 Mice ...

  38. TR-005: Proflavine (CASRN 952-23-8) 3.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr005.pdf

    ... Thin-layer chromatography in a 1,4-dioxane : ammonium hydroxide solvent system, as visualized by ultraviolet light and furfural, showed three trace impurities. A second analysis in ...

  39. Minutes: BSC; Sept. 27, 1983 638KB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/archives/1983/september/bsc_mins19830927_508.pdf

    ... butyralde hyde, crotonaldehyde and furfural, recommended to be tested for various ... Citra l Butyraldehyde Crotonaldehyde Furfural BOARD OF SCIENTIFIC COUNSELOR S ON ...

  40. Minutes: BSC TRRS; April 18, 1988 4.9MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1988/apr/88apr18trrsmins_508.pdf

    ... Bucher saicrlrtJrosemide would be considered for bone marrow studies. The link with other furans such as furfural recently reported to be carcinogenic might be explored. Dr . ...

  41. TR-105: m-Cresidine (CASRN 102-50-1) 4.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr105.pdf

    ... two solvent systems (chloroform and benzene:ethyl acetate), and each plate was visualized with ultra- violet light and furfural. TLC results indicated the presence of one impurity. ...

  42. TR-109: 4-Nitroanthranilic Acid (CASRN 619-17-0) 4.3MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr109.pdf

    ... Each plate was visualized by ultraviolet light and by furfural. The presence of three impurities of lower motility than the major compound was indicated by these analyses. ...

  43. TR-085: 4-Chloro-m-phenylenediamine (CASRN 5131-60-2) 3.1MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr085.pdf

    ... Thin-layer chromatography utilizing two solvent systems (benzene:methanol and methanol:acetic acid) and visualized with ultraviolet light and furfural revealed, respectively, one ...

  44. TR-130: Aniline Hydrochloride (CASRN 142-04-1) 3.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr130.pdf

    ... (acetone:benzene:ammonia and ethyl acetate:chloroform), and plates were visualized with ultraviolet light and furfural. Each plate showed one or more nonmotile impuri- ties. ...

  45. TR-171: 2,4-Dimethoxyaniline Hydrochloride (CASRN 54150-69-5... 3.0MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr171.pdf

    ... TLC was performed utilizing two solvent systems (i.e., ethanol:water and chloroform). Each plate was visualized with iodine vapor, furfural and UV light of 254 and 366 nm. Using ...

  46. TR-180: 4-Nitro-o-phenylenediamine (CASRN 99-56-9) 2.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr180.pdf

    ... Each plate, visualized with 254 and 367 nm light and furfural, revealed one major spot and one trace impurity. Vapor-phase chromatography revealed one homogeneous peak. The results ...

  47. TOX-104: (+)-Usnic Acid (CASRN 7562-61-0) Administered in Feed... 4.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/st_rpts/tox104_508.pdf

    ... ethyl acetate, and more soluble in tetrahydrofuran (+)-Usnic Acid, NTP TOX 104 2 and furfural. 11; 12 The sodium dihydrate salt of usnic acid is slightly soluble in water. 11 ...

  48. Nomination Background: 2,3-Butanedione (CASRN: 431-03-8) 1.8MB

    https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/artificial_butter_flavoring_508be.pdf

    ... Minor NL Furfural; 2-Furaldehyde; 2-Hydroxymethylfuran 98-01-1 7362 x 150 NL Minor (w/ octane) ? Major Major NL Hexane 110-54-3 8058 100 NL ? ? Major Major NL 32 Chemical ...

  49. Minutes: BSC TRRS; Dec. 9, 1997 1.8MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/about_ntp/bsc/trrs/1997/dec/trrs9dec1997mins_508.pdf

    ... as part of a class study with furan and furfural, noting that cholangiocarcinomas and other hepatocellular neoplasms were significant neoplastic findings with furan and furfural. ...

  50. TR-356: Furosemide (CASRN 54-31-9) in F344/N Rats and B6C3F1Mice... 11.6MB

    https://ntp.niehs.nih.gov/sites/default/files/ntp/htdocs/lt_rpts/tr356.pdf

    ... Bucher said that furosemide would bo considered for bone marrow studies. The link with other furans such as furfural, recently reported ta be carcinogenic, tnight be explored. Dr. ...

 
of 3